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The map label for this gene is fabZ

Identifier: 15603860

GI number: 15603860

Start: 2236708

End: 2237166

Strand: Direct

Name: fabZ

Synonym: PM1995

Alternate gene names: 15603860

Gene position: 2236708-2237166 (Clockwise)

Preceding gene: 15603859

Following gene: 15603861

Centisome position: 99.08

GC content: 41.83

Gene sequence:

>459_bases
GTGACAACTGAAACTACCACAACAAAAATCATTGAAGCAAATGAAATTATGAAATTGCTTCCTCACCGTTATCCTTTTTT
ATTAGTGGATCGTGTGGTGGATTATGAAGAAGGTAAATGGCTTAAAGCTGTAAAAAATATTAGCGTAAATGAGCCTTGCT
TTACGGGACATTTCCCAGAACAACCGATTTTTCCGGGTGTGTTGATTTTGGAAGCCATGGCACAAGCGACGGGGGTGCTC
GCCTGTAAAACTTACCGTCAATTAGAAAATGAAATTTATTATTTTGCTGCAATTGATAATGCGCGCTTTAAACGTCCTGT
GTTGCCTGGTGATCAAATGGTGTTAGAAGTTCACTTCTTGAAAGAGCGTCGCGGTATTACGCGTTTCACTGGTGTGGCAA
CCGTAGATGGTCAAGTGGTGTGCGAAGCAGAATTAATGTGTGCTCGTCGTCCCGCATAA

Upstream 100 bases:

>100_bases
AAACGAACCGCACTTTTTTGTGGTGCGTTTTGTATTCAGCACGTAAATACCGTATAATTTTGAATGTTTTATCGTTTTAT
TTTTATTGGAAGGTACTATT

Downstream 100 bases:

>100_bases
TAAGCAAGGAGTAAAATATGATCCACCCAACCGCACAGATTCATCCTACCTCAATTGTGGAGGCTGGAGCAAAAATTGGT
GAGAATGTTGTTATCGGTCC

Product: (3R)-hydroxymyristoyl-ACP dehydratase

Products: NA

Alternate protein names: (3R)-hydroxymyristoyl ACP dehydrase

Number of amino acids: Translated: 152; Mature: 151

Protein sequence:

>152_residues
MTTETTTTKIIEANEIMKLLPHRYPFLLVDRVVDYEEGKWLKAVKNISVNEPCFTGHFPEQPIFPGVLILEAMAQATGVL
ACKTYRQLENEIYYFAAIDNARFKRPVLPGDQMVLEVHFLKERRGITRFTGVATVDGQVVCEAELMCARRPA

Sequences:

>Translated_152_residues
MTTETTTTKIIEANEIMKLLPHRYPFLLVDRVVDYEEGKWLKAVKNISVNEPCFTGHFPEQPIFPGVLILEAMAQATGVL
ACKTYRQLENEIYYFAAIDNARFKRPVLPGDQMVLEVHFLKERRGITRFTGVATVDGQVVCEAELMCARRPA
>Mature_151_residues
TTETTTTKIIEANEIMKLLPHRYPFLLVDRVVDYEEGKWLKAVKNISVNEPCFTGHFPEQPIFPGVLILEAMAQATGVLA
CKTYRQLENEIYYFAAIDNARFKRPVLPGDQMVLEVHFLKERRGITRFTGVATVDGQVVCEAELMCARRPA

Specific function: Involved in saturated fatty acids biosynthesis

COG id: COG0764

COG function: function code I; 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioester dehydratase family. FabZ subfamily

Homologues:

Organism=Escherichia coli, GI1786377, Length=146, Percent_Identity=70.5479452054795, Blast_Score=221, Evalue=2e-59,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FABZ_PASMU (Q9CJK9)

Other databases:

- EMBL:   AE004439
- RefSeq:   NP_246934.1
- ProteinModelPortal:   Q9CJK9
- SMR:   Q9CJK9
- GeneID:   1245342
- GenomeReviews:   AE004439_GR
- KEGG:   pmu:PM1995
- NMPDR:   fig|272843.1.peg.1996
- HOGENOM:   HBG433282
- OMA:   KERRGVA
- ProtClustDB:   PRK00006
- BioCyc:   PMUL272843:PM1995-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00406
- InterPro:   IPR013114
- InterPro:   IPR010084
- TIGRFAMs:   TIGR01750

Pfam domain/function: PF07977 FabA

EC number: 4.2.1.-

Molecular weight: Translated: 17291; Mature: 17160

Theoretical pI: Translated: 6.76; Mature: 6.76

Prosite motif: NA

Important sites: ACT_SITE 57-57

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTETTTTKIIEANEIMKLLPHRYPFLLVDRVVDYEEGKWLKAVKNISVNEPCFTGHFPE
CCCCCCCEEEECHHHHHHHCCCCCCHHHHHHHHCCCCCCHHHHHHCCCCCCCCCCCCCCC
QPIFPGVLILEAMAQATGVLACKTYRQLENEIYYFAAIDNARFKRPVLPGDQMVLEVHFL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCCCCCCEEEEEEEH
KERRGITRFTGVATVDGQVVCEAELMCARRPA
HHCCCCCCCCCEEEECCEEEEHHHHHHCCCCC
>Mature Secondary Structure 
TTETTTTKIIEANEIMKLLPHRYPFLLVDRVVDYEEGKWLKAVKNISVNEPCFTGHFPE
CCCCCCEEEECHHHHHHHCCCCCCHHHHHHHHCCCCCCHHHHHHCCCCCCCCCCCCCCC
QPIFPGVLILEAMAQATGVLACKTYRQLENEIYYFAAIDNARFKRPVLPGDQMVLEVHFL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCCCCCCEEEEEEEH
KERRGITRFTGVATVDGQVVCEAELMCARRPA
HHCCCCCCCCCEEEECCEEEEHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Carbon-Oxygen Lyases; Hydro-Lyases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11248100