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The map label for this gene is yaeL [C]

Identifier: 15603856

GI number: 15603856

Start: 2231151

End: 2232479

Strand: Direct

Name: yaeL [C]

Synonym: PM1991

Alternate gene names: 15603856

Gene position: 2231151-2232479 (Clockwise)

Preceding gene: 15603855

Following gene: 15603857

Centisome position: 98.83

GC content: 41.23

Gene sequence:

>1329_bases
ATGTCATTTTTATGGTCATTTGCGTCGTTTATTATTGTTATTAGTGTACTTGTTGCAGTCCATGAGTATGGGCACTTTTG
GGCTGCGAGAAAGTGCGGTATTCAGGTTCATCGTTTTTCAATTGGTTTTGGTAAAGTACTTTGGTCGCGCACAGATAAAC
AGGGAACTGAATTTGTCATATCTGCGATTCCACTCGGTGGTTATGTCAAAATGCTAGATGGACGTAATGAAGTGGTTCCG
CCTGAATTGAGCTCACGTGCATTTGATCAAAAAAGTGTACTACAGCGCGCTTTCGTGATTGCAGCAGGTCCTATCGCGAA
CTTCTTATTTGCGATTCTGGCATATTTTACGATTTATACTGTGGGTATCCCGACAGTAAAACCTGTCATTGCGGACATTT
CATCAAATTCTATTGCTGCCCAAGCCCAGATTGAACCGAATACACAAATTATGGCGGTAGATGGCACAAAAGTGAGCGAT
TGGGAAACCATTAATATGTTGTTGGCAACTAAGATGGGAAATGATGAAATTCACCTAACGTTATCGCCTTTTGGCTCGTC
TATTGAGCAACATAAAGTACTCAATACGAAAGACTGGCGTTTTGATCCTGAAAAAGAAAGTGCCATGAGCTCACTTGGTC
TGCAACCTGTGAGAACTAAAGTGGACATGATTTTGTCTAAGGTCGAGGTCAACTCACCTGCCGATAAAGCAGGCTTAAAA
GCCGGTGATCGCATTTATGCGGGAGAGCAGTTAATTAGTTGGCAACAATTTGTACAGTTTGTACAAGAAGGAAAACCGTT
TAATGTTAAGGTTGAACGTGATGGTCAGTTTTCCTTTGTTGTTCTGACACCAGAATTAAACAAAAAAGGACGCTGGTATG
TGGGGATTGCGCCGACGGCAGCCCCGATCTCTGATATATATCGAACCGAATTAAAATATGGTATTCTTGAGGCCTTACAG
AAAGGGGTTGAGAAGACGATACAGCTTTCATGGTTAACGATAAAAGTGATTGGCAAGCTCTTTACCGGTGATCTGGCTTT
GAAGAATTTAGGTGGTCCGATTTCTATTGCGAAAGGTGCGGGCATCTCTTCTGAAATTGGGTTGATTTATTACCTCGGTT
TTATGGCATTGATCAGTGTGAATTTAGGCATAATGAACTTATTTCCATTACCTGTTCTTGATGGTGGTCATTTAGTCTTT
TTAGCGGCTGAGGCGGTCCGAGGTAAACCACTCTCAGAACGTATTCAAAATTTGAGTTATCGAATTGGTGCAGCGATATT
AATGGCTTTAATGGGATTTGCACTCTTTAATGATTTCTTACGTTTATAA

Upstream 100 bases:

>100_bases
TGGTATTTTAGATCGGATTGATAGTTTAACGGCGGCCGTTCCGTTCTTTGCTTATTTTTACTTTTTCGTGATTTCATGAT
GCATTAGGAACAACAGATTT

Downstream 100 bases:

>100_bases
TTAATTTTACTCACAGGATAACATTCACGATGAAAAAACTTTTAATTGCGAGCTTATTATTTGGTTCAACCACTGCATTT
GCTGCGCCGTTTGTAGTGAA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 442; Mature: 441

Protein sequence:

>442_residues
MSFLWSFASFIIVISVLVAVHEYGHFWAARKCGIQVHRFSIGFGKVLWSRTDKQGTEFVISAIPLGGYVKMLDGRNEVVP
PELSSRAFDQKSVLQRAFVIAAGPIANFLFAILAYFTIYTVGIPTVKPVIADISSNSIAAQAQIEPNTQIMAVDGTKVSD
WETINMLLATKMGNDEIHLTLSPFGSSIEQHKVLNTKDWRFDPEKESAMSSLGLQPVRTKVDMILSKVEVNSPADKAGLK
AGDRIYAGEQLISWQQFVQFVQEGKPFNVKVERDGQFSFVVLTPELNKKGRWYVGIAPTAAPISDIYRTELKYGILEALQ
KGVEKTIQLSWLTIKVIGKLFTGDLALKNLGGPISIAKGAGISSEIGLIYYLGFMALISVNLGIMNLFPLPVLDGGHLVF
LAAEAVRGKPLSERIQNLSYRIGAAILMALMGFALFNDFLRL

Sequences:

>Translated_442_residues
MSFLWSFASFIIVISVLVAVHEYGHFWAARKCGIQVHRFSIGFGKVLWSRTDKQGTEFVISAIPLGGYVKMLDGRNEVVP
PELSSRAFDQKSVLQRAFVIAAGPIANFLFAILAYFTIYTVGIPTVKPVIADISSNSIAAQAQIEPNTQIMAVDGTKVSD
WETINMLLATKMGNDEIHLTLSPFGSSIEQHKVLNTKDWRFDPEKESAMSSLGLQPVRTKVDMILSKVEVNSPADKAGLK
AGDRIYAGEQLISWQQFVQFVQEGKPFNVKVERDGQFSFVVLTPELNKKGRWYVGIAPTAAPISDIYRTELKYGILEALQ
KGVEKTIQLSWLTIKVIGKLFTGDLALKNLGGPISIAKGAGISSEIGLIYYLGFMALISVNLGIMNLFPLPVLDGGHLVF
LAAEAVRGKPLSERIQNLSYRIGAAILMALMGFALFNDFLRL
>Mature_441_residues
SFLWSFASFIIVISVLVAVHEYGHFWAARKCGIQVHRFSIGFGKVLWSRTDKQGTEFVISAIPLGGYVKMLDGRNEVVPP
ELSSRAFDQKSVLQRAFVIAAGPIANFLFAILAYFTIYTVGIPTVKPVIADISSNSIAAQAQIEPNTQIMAVDGTKVSDW
ETINMLLATKMGNDEIHLTLSPFGSSIEQHKVLNTKDWRFDPEKESAMSSLGLQPVRTKVDMILSKVEVNSPADKAGLKA
GDRIYAGEQLISWQQFVQFVQEGKPFNVKVERDGQFSFVVLTPELNKKGRWYVGIAPTAAPISDIYRTELKYGILEALQK
GVEKTIQLSWLTIKVIGKLFTGDLALKNLGGPISIAKGAGISSEIGLIYYLGFMALISVNLGIMNLFPLPVLDGGHLVFL
AAEAVRGKPLSERIQNLSYRIGAAILMALMGFALFNDFLRL

Specific function: Unknown

COG id: COG0750

COG function: function code M; Predicted membrane-associated Zn-dependent proteases 1

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PDZ (DHR) domain

Homologues:

Organism=Escherichia coli, GI1786373, Length=449, Percent_Identity=53.2293986636971, Blast_Score=480, Evalue=1e-137,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y1991_PASMU (Q9CJL2)

Other databases:

- EMBL:   AE004439
- RefSeq:   NP_246930.1
- ProteinModelPortal:   Q9CJL2
- MEROPS:   M50.004
- GeneID:   1245338
- GenomeReviews:   AE004439_GR
- KEGG:   pmu:PM1991
- NMPDR:   fig|272843.1.peg.1992
- HOGENOM:   HBG664087
- OMA:   HGTEFVV
- ProtClustDB:   CLSK870688
- BioCyc:   PMUL272843:PM1991-MONOMER
- GO:   GO:0006508
- InterPro:   IPR001478
- InterPro:   IPR004387
- InterPro:   IPR008915
- SMART:   SM00228
- TIGRFAMs:   TIGR00054

Pfam domain/function: PF00595 PDZ; PF02163 Peptidase_M50; SSF50156 PDZ

EC number: NA

Molecular weight: Translated: 48609; Mature: 48478

Theoretical pI: Translated: 9.46; Mature: 9.46

Prosite motif: PS50106 PDZ; PS00142 ZINC_PROTEASE

Important sites: ACT_SITE 22-22

Signals:

None

Transmembrane regions:

HASH(0xd6eda80)-; HASH(0xea4c760)-; HASH(0xf1eff90)-;

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFLWSFASFIIVISVLVAVHEYGHFWAARKCGIQVHRFSIGFGKVLWSRTDKQGTEFVI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHCCCCCCCCEEEE
SAIPLGGYVKMLDGRNEVVPPELSSRAFDQKSVLQRAFVIAAGPIANFLFAILAYFTIYT
EEECCCCEEEEECCCCCCCCCCHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
VGIPTVKPVIADISSNSIAAQAQIEPNTQIMAVDGTKVSDWETINMLLATKMGNDEIHLT
CCCCCHHHHHHHCCCCCEEEEEEECCCCEEEEECCCCCCCHHHHEEEEEEECCCCEEEEE
LSPFGSSIEQHKVLNTKDWRFDPEKESAMSSLGLQPVRTKVDMILSKVEVNSPADKAGLK
ECCCCCCHHHHCCCCCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCHHCCC
AGDRIYAGEQLISWQQFVQFVQEGKPFNVKVERDGQFSFVVLTPELNKKGRWYVGIAPTA
CCCEEECCHHHHHHHHHHHHHHCCCCEEEEEECCCCEEEEEECCCCCCCCCEEEEECCCC
APISDIYRTELKYGILEALQKGVEKTIQLSWLTIKVIGKLFTGDLALKNLGGPISIAKGA
CHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEHHHHHHHHHHCCHHHHHCCCCEEEECCC
GISSEIGLIYYLGFMALISVNLGIMNLFPLPVLDGGHLVFLAAEAVRGKPLSERIQNLSY
CCCCCHHHHHHHHHHHHHHHCCCCEEECCCCEECCCCEEEEEEHHHCCCCHHHHHHHHHH
RIGAAILMALMGFALFNDFLRL
HHHHHHHHHHHHHHHHHHHHCH
>Mature Secondary Structure 
SFLWSFASFIIVISVLVAVHEYGHFWAARKCGIQVHRFSIGFGKVLWSRTDKQGTEFVI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHCCCCCCCCEEEE
SAIPLGGYVKMLDGRNEVVPPELSSRAFDQKSVLQRAFVIAAGPIANFLFAILAYFTIYT
EEECCCCEEEEECCCCCCCCCCHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
VGIPTVKPVIADISSNSIAAQAQIEPNTQIMAVDGTKVSDWETINMLLATKMGNDEIHLT
CCCCCHHHHHHHCCCCCEEEEEEECCCCEEEEECCCCCCCHHHHEEEEEEECCCCEEEEE
LSPFGSSIEQHKVLNTKDWRFDPEKESAMSSLGLQPVRTKVDMILSKVEVNSPADKAGLK
ECCCCCCHHHHCCCCCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCHHCCC
AGDRIYAGEQLISWQQFVQFVQEGKPFNVKVERDGQFSFVVLTPELNKKGRWYVGIAPTA
CCCEEECCHHHHHHHHHHHHHHCCCCEEEEEECCCCEEEEEECCCCCCCCCEEEEECCCC
APISDIYRTELKYGILEALQKGVEKTIQLSWLTIKVIGKLFTGDLALKNLGGPISIAKGA
CHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEHHHHHHHHHHCCHHHHHCCCCEEEECCC
GISSEIGLIYYLGFMALISVNLGIMNLFPLPVLDGGHLVFLAAEAVRGKPLSERIQNLSY
CCCCCHHHHHHHHHHHHHHHCCCCEEECCCCEECCCCEEEEEEHHHCCCCHHHHHHHHHH
RIGAAILMALMGFALFNDFLRL
HHHHHHHHHHHHHHHHHHHHCH

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11248100