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The map label for this gene is glpT [H]

Identifier: 15603308

GI number: 15603308

Start: 1629582

End: 1631027

Strand: Direct

Name: glpT [H]

Synonym: PM1443

Alternate gene names: 15603308

Gene position: 1629582-1631027 (Clockwise)

Preceding gene: 15603304

Following gene: 15603309

Centisome position: 72.19

GC content: 43.5

Gene sequence:

>1446_bases
ATGATTGGTCCATTTAAACCCGCACCGCATATTGCGGAACTTCCCGCGGATAAAATTGATGCACGCTATCGTTTCTTACG
TTGGCAAGTGTTTGCTGGCATCTTTTTTGGTTACGCCGCTTATTATTTCGTCCGTGCAAACTTCGATTTAGCACAAAAAG
GCTTGATTGAAGCTGGTATGTATAACAAAGCTGAACTTGGGATTATCGGTACAGGGGCGGGTTTGGCATACGGCTTATCG
AAATTCTTTATGGCATCCATTTCCGATCGCTCAAACCCAAAAGTCTTTTTACCTTTCGGTTTGCTCTTATCTGGTTTGTG
TATGACGATGATGGGTCTCATGCCATGGGCAACCTCAGGGATTGCTGTGATGTTCATCATGATTTTCTTAAACGGTTGGT
TCCAAGGTATGGGTTGGCCACCATGTGGTCGTACAATGGTGCATTGGTGGTCTAAATCTGAACGTGGTTCGATCGTGTCA
ATTTGGAATACCGCGCATAACTTAGGGGGAATGGTACCAGGGGCGATGGTGTTACTCGCCAGTGCCGTTTACTTCAGCAC
ACATGGTGTTGAAGCGACCGCAAAAGACGTTTGGCAACAAGCTCTTTATTATCCAGGTATTGCAGCCATGATTGCGGCGA
TTCCAATTTATTTTATGATGAAAGACACACCACAATCTTGTGGTTTACCTCCTATCGAAAAATGGCGTAATGATTACCCA
GACGATTACAACGAAAAAACCTATGAGCATGATTTAAGCACAAAAGATATTTTCGTGACTTACGTCTTAAAAAATCGCCT
ACTTTGGTATATCGCGATTGCTAACGTATTCGTGTATTTAATCCGCTACGGTGTCTTAAAATGGTCGCCAGTGTACCTTG
GCGAAGTGAAACACTTCAACATCAAAGGGACTGCTTGGGCGTACACTATTTATGAATTAGCCGCGGTTCCAGGGACTTTA
TTATGTGGTTGGGTCTCTGATAAAGTGTTCAAAGGTAAACGTGGTTTAACAGGTTTCATTTTCATGATTTTAACCACTGC
CGCCGTCGTAGCATTATGGTTAAACCCAGCAACACCAGAAGCTGAATTAGCTAAATATGCAGGTCATGCATGGTATGAAA
ACCCATATCAGTTAATGGACTTCATTCTCATGACAACCATTGGTTTCTTAATCTACGGTCCTGTGATGCTTATCGGTTTA
CATGCGCTTGAGCTTGCGCCGAAAAAAGCGGCAGGGACATCTGCAGGTTTCACCGGTTTATTTGGTTACTTAGGTGGTAC
TGTATCTGCATCAGCCGTAGTGGGTTGGGCTGCCGAATATTATGGCTGGGACGGTGGTTTCTACGTCATGATCGCAGGTG
GGGTACTCGCTATCTTATTAATGTTCATCACTATGATTGAAGAAAGTAAACATAAAGCCCGTTTAGAAGATCATTACGGC
AAATAA

Upstream 100 bases:

>100_bases
TCAGTTTTTTCTTTTCCCTTATTATTTATGCGAGATTCTTGTAAAAAGAACGCAGTATAACAACGTCAAAAATCTTAATT
AAACCCTATTGGAGAAGAGT

Downstream 100 bases:

>100_bases
AAAATGAATAAAAAGGAAGAATCACTATTCTTCCTTTTTTTCTTTCTCATCGCATTGCAATGAAATCATTTTACACTTCA
TTCTGTTTAACACAGCAGTA

Product: GlpT

Products: Proton [Cytoplasm]; glycerol-3-phosphate [Cytoplasm] [C]

Alternate protein names: G-3-P transporter; G-3-P permease [H]

Number of amino acids: Translated: 481; Mature: 481

Protein sequence:

>481_residues
MIGPFKPAPHIAELPADKIDARYRFLRWQVFAGIFFGYAAYYFVRANFDLAQKGLIEAGMYNKAELGIIGTGAGLAYGLS
KFFMASISDRSNPKVFLPFGLLLSGLCMTMMGLMPWATSGIAVMFIMIFLNGWFQGMGWPPCGRTMVHWWSKSERGSIVS
IWNTAHNLGGMVPGAMVLLASAVYFSTHGVEATAKDVWQQALYYPGIAAMIAAIPIYFMMKDTPQSCGLPPIEKWRNDYP
DDYNEKTYEHDLSTKDIFVTYVLKNRLLWYIAIANVFVYLIRYGVLKWSPVYLGEVKHFNIKGTAWAYTIYELAAVPGTL
LCGWVSDKVFKGKRGLTGFIFMILTTAAVVALWLNPATPEAELAKYAGHAWYENPYQLMDFILMTTIGFLIYGPVMLIGL
HALELAPKKAAGTSAGFTGLFGYLGGTVSASAVVGWAAEYYGWDGGFYVMIAGGVLAILLMFITMIEESKHKARLEDHYG
K

Sequences:

>Translated_481_residues
MIGPFKPAPHIAELPADKIDARYRFLRWQVFAGIFFGYAAYYFVRANFDLAQKGLIEAGMYNKAELGIIGTGAGLAYGLS
KFFMASISDRSNPKVFLPFGLLLSGLCMTMMGLMPWATSGIAVMFIMIFLNGWFQGMGWPPCGRTMVHWWSKSERGSIVS
IWNTAHNLGGMVPGAMVLLASAVYFSTHGVEATAKDVWQQALYYPGIAAMIAAIPIYFMMKDTPQSCGLPPIEKWRNDYP
DDYNEKTYEHDLSTKDIFVTYVLKNRLLWYIAIANVFVYLIRYGVLKWSPVYLGEVKHFNIKGTAWAYTIYELAAVPGTL
LCGWVSDKVFKGKRGLTGFIFMILTTAAVVALWLNPATPEAELAKYAGHAWYENPYQLMDFILMTTIGFLIYGPVMLIGL
HALELAPKKAAGTSAGFTGLFGYLGGTVSASAVVGWAAEYYGWDGGFYVMIAGGVLAILLMFITMIEESKHKARLEDHYG
K
>Mature_481_residues
MIGPFKPAPHIAELPADKIDARYRFLRWQVFAGIFFGYAAYYFVRANFDLAQKGLIEAGMYNKAELGIIGTGAGLAYGLS
KFFMASISDRSNPKVFLPFGLLLSGLCMTMMGLMPWATSGIAVMFIMIFLNGWFQGMGWPPCGRTMVHWWSKSERGSIVS
IWNTAHNLGGMVPGAMVLLASAVYFSTHGVEATAKDVWQQALYYPGIAAMIAAIPIYFMMKDTPQSCGLPPIEKWRNDYP
DDYNEKTYEHDLSTKDIFVTYVLKNRLLWYIAIANVFVYLIRYGVLKWSPVYLGEVKHFNIKGTAWAYTIYELAAVPGTL
LCGWVSDKVFKGKRGLTGFIFMILTTAAVVALWLNPATPEAELAKYAGHAWYENPYQLMDFILMTTIGFLIYGPVMLIGL
HALELAPKKAAGTSAGFTGLFGYLGGTVSASAVVGWAAEYYGWDGGFYVMIAGGVLAILLMFITMIEESKHKARLEDHYG
K

Specific function: Responsible for glycerol-3-phosphate uptake [H]

COG id: COG2271

COG function: function code G; Sugar phosphate permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family [H]

Homologues:

Organism=Homo sapiens, GI256219543, Length=452, Percent_Identity=25.4424778761062, Blast_Score=135, Evalue=8e-32,
Organism=Homo sapiens, GI256219598, Length=435, Percent_Identity=25.0574712643678, Blast_Score=131, Evalue=1e-30,
Organism=Homo sapiens, GI4503847, Length=435, Percent_Identity=25.0574712643678, Blast_Score=131, Evalue=1e-30,
Organism=Homo sapiens, GI256219483, Length=435, Percent_Identity=25.0574712643678, Blast_Score=131, Evalue=1e-30,
Organism=Homo sapiens, GI256219564, Length=358, Percent_Identity=23.463687150838, Blast_Score=89, Evalue=7e-18,
Organism=Escherichia coli, GI1788573, Length=481, Percent_Identity=59.2515592515593, Blast_Score=581, Evalue=1e-167,
Organism=Escherichia coli, GI87082310, Length=466, Percent_Identity=33.6909871244635, Blast_Score=254, Evalue=1e-68,
Organism=Escherichia coli, GI2367259, Length=455, Percent_Identity=32.7472527472527, Blast_Score=206, Evalue=3e-54,
Organism=Caenorhabditis elegans, GI133930953, Length=483, Percent_Identity=21.1180124223602, Blast_Score=78, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17564204, Length=414, Percent_Identity=24.1545893719807, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17542316, Length=474, Percent_Identity=21.5189873417722, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17564202, Length=408, Percent_Identity=24.0196078431373, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI133901856, Length=470, Percent_Identity=21.9148936170213, Blast_Score=72, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI133901854, Length=470, Percent_Identity=21.9148936170213, Blast_Score=72, Evalue=9e-13,
Organism=Drosophila melanogaster, GI24656866, Length=542, Percent_Identity=20.479704797048, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI45550478, Length=542, Percent_Identity=20.479704797048, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24656861, Length=542, Percent_Identity=20.2952029520295, Blast_Score=78, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005267
- InterPro:   IPR000849
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR021159 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 53410; Mature: 53410

Theoretical pI: Translated: 8.66; Mature: 8.66

Prosite motif: PS50850 MFS ; PS00942 GLPT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIGPFKPAPHIAELPADKIDARYRFLRWQVFAGIFFGYAAYYFVRANFDLAQKGLIEAGM
CCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCC
YNKAELGIIGTGAGLAYGLSKFFMASISDRSNPKVFLPFGLLLSGLCMTMMGLMPWATSG
CCCCCEEEEECCCHHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHHCCHH
IAVMFIMIFLNGWFQGMGWPPCGRTMVHWWSKSERGSIVSIWNTAHNLGGMVPGAMVLLA
HHHHHHHHHHHHHHCCCCCCCCCCHHHHHHCCCCCCCEEEEEHHHHHHCCCCHHHHHHHH
SAVYFSTHGVEATAKDVWQQALYYPGIAAMIAAIPIYFMMKDTPQSCGLPPIEKWRNDYP
HHHHHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHEEECCCCCCCCCCCHHHHCCCCC
DDYNEKTYEHDLSTKDIFVTYVLKNRLLWYIAIANVFVYLIRYGVLKWSPVYLGEVKHFN
CCCCCCCHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCEEEEE
IKGTAWAYTIYELAAVPGTLLCGWVSDKVFKGKRGLTGFIFMILTTAAVVALWLNPATPE
CCCCHHHHHHHHHHHCCHHEEEHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCH
AELAKYAGHAWYENPYQLMDFILMTTIGFLIYGPVMLIGLHALELAPKKAAGTSAGFTGL
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHH
FGYLGGTVSASAVVGWAAEYYGWDGGFYVMIAGGVLAILLMFITMIEESKHKARLEDHYG
HHHHCCCHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
K
C
>Mature Secondary Structure
MIGPFKPAPHIAELPADKIDARYRFLRWQVFAGIFFGYAAYYFVRANFDLAQKGLIEAGM
CCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCC
YNKAELGIIGTGAGLAYGLSKFFMASISDRSNPKVFLPFGLLLSGLCMTMMGLMPWATSG
CCCCCEEEEECCCHHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHHCCHH
IAVMFIMIFLNGWFQGMGWPPCGRTMVHWWSKSERGSIVSIWNTAHNLGGMVPGAMVLLA
HHHHHHHHHHHHHHCCCCCCCCCCHHHHHHCCCCCCCEEEEEHHHHHHCCCCHHHHHHHH
SAVYFSTHGVEATAKDVWQQALYYPGIAAMIAAIPIYFMMKDTPQSCGLPPIEKWRNDYP
HHHHHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHEEECCCCCCCCCCCHHHHCCCCC
DDYNEKTYEHDLSTKDIFVTYVLKNRLLWYIAIANVFVYLIRYGVLKWSPVYLGEVKHFN
CCCCCCCHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCEEEEE
IKGTAWAYTIYELAAVPGTLLCGWVSDKVFKGKRGLTGFIFMILTTAAVVALWLNPATPE
CCCCHHHHHHHHHHHCCHHEEEHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCH
AELAKYAGHAWYENPYQLMDFILMTTIGFLIYGPVMLIGLHALELAPKKAAGTSAGFTGL
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHH
FGYLGGTVSASAVVGWAAEYYGWDGGFYVMIAGGVLAILLMFITMIEESKHKARLEDHYG
HHHHCCCHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
K
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; glycerol-3-phosphate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + glycerol-3-phosphate [Periplasm] = Proton [Cytoplasm] + glycerol-3-phosphate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800; 9714837 [H]