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The map label for this gene is rnpA [H]

Identifier: 15603028

GI number: 15603028

Start: 1358802

End: 1359194

Strand: Direct

Name: rnpA [H]

Synonym: PM1163

Alternate gene names: 15603028

Gene position: 1358802-1359194 (Clockwise)

Preceding gene: 15603027

Following gene: 15603029

Centisome position: 60.19

GC content: 40.46

Gene sequence:

>393_bases
ATCGTTATCAGCATAATCTTAATCCCTATTGGTGTGATTAAGCTGAATTTTTCGAGGGAGTTACGTTTGTTAACTCCCCT
TCATTTTAAATACGTCTTCGAACAGCCGTTCCGTGCTAGTACACCTGAACTTACCATTCTTGCTCGTCCCAATAATCTCG
CTCATCCTCGCTTAGGGTTAACTGTCGCGAAAAAGCATTTAAAAAAAGCACATGATCGCAATCGCATCAAACGCTTATGC
CGAGAAAGTTTCCGCCTAGCACAGTATAAACTCCCCAATTGCGATTTTGTTATTGTGGCGAAACAGGGAATTGGTAAATT
AGACAACAGGACACTCACACAAACATTGGATAAATTATGGCAAAGACACATTCGCTTAGCTCAAAAATCTTGA

Upstream 100 bases:

>100_bases
CATCAGTGTTAAAACGTAGTCGTACACACGGTTTCCGTGCTCGTATGGCAACTAAAAACGGCCGCCAAGTTTTAGCTCGT
CGTCGTGCTAAAGGTCGTAA

Downstream 100 bases:

>100_bases
TTGGGTTAATTCGTGTCTATCAAGTTGTCATTAGCCCACTCATTGGCCCCCGTTGTCGTTTCACACCGACATGTTCTTGC
TATGGGATTGAAGCAGTAAA

Product: ribonuclease P

Products: NA

Alternate protein names: RNase P protein; RNaseP protein; Protein C5 [H]

Number of amino acids: Translated: 130; Mature: 130

Protein sequence:

>130_residues
MVISIILIPIGVIKLNFSRELRLLTPLHFKYVFEQPFRASTPELTILARPNNLAHPRLGLTVAKKHLKKAHDRNRIKRLC
RESFRLAQYKLPNCDFVIVAKQGIGKLDNRTLTQTLDKLWQRHIRLAQKS

Sequences:

>Translated_130_residues
MVISIILIPIGVIKLNFSRELRLLTPLHFKYVFEQPFRASTPELTILARPNNLAHPRLGLTVAKKHLKKAHDRNRIKRLC
RESFRLAQYKLPNCDFVIVAKQGIGKLDNRTLTQTLDKLWQRHIRLAQKS
>Mature_130_residues
MVISIILIPIGVIKLNFSRELRLLTPLHFKYVFEQPFRASTPELTILARPNNLAHPRLGLTVAKKHLKKAHDRNRIKRLC
RESFRLAQYKLPNCDFVIVAKQGIGKLDNRTLTQTLDKLWQRHIRLAQKS

Specific function: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-lead

COG id: COG0594

COG function: function code J; RNase P protein component

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rnpA family [H]

Homologues:

Organism=Escherichia coli, GI1790139, Length=119, Percent_Identity=63.8655462184874, Blast_Score=164, Evalue=1e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020568
- InterPro:   IPR014721
- InterPro:   IPR000100
- ProDom:   PD003629 [H]

Pfam domain/function: PF00825 Ribonuclease_P [H]

EC number: =3.1.26.5 [H]

Molecular weight: Translated: 15158; Mature: 15158

Theoretical pI: Translated: 11.64; Mature: 11.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVISIILIPIGVIKLNFSRELRLLTPLHFKYVFEQPFRASTPELTILARPNNLAHPRLGL
CEEEEEEEEEEEEEECCCCCEEECCHHHHHHHHCCCCCCCCCCEEEEECCCCCCCCCHHH
TVAKKHLKKAHDRNRIKRLCRESFRLAQYKLPNCDFVIVAKQGIGKLDNRTLTQTLDKLW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHH
QRHIRLAQKS
HHHHHHHCCC
>Mature Secondary Structure
MVISIILIPIGVIKLNFSRELRLLTPLHFKYVFEQPFRASTPELTILARPNNLAHPRLGL
CEEEEEEEEEEEEEECCCCCEEECCHHHHHHHHCCCCCCCCCCEEEEECCCCCCCCCHHH
TVAKKHLKKAHDRNRIKRLCRESFRLAQYKLPNCDFVIVAKQGIGKLDNRTLTQTLDKLW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHH
QRHIRLAQKS
HHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11248100 [H]