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The map label for this gene is cmoA

Identifier: 15602850

GI number: 15602850

Start: 1155241

End: 1155966

Strand: Direct

Name: cmoA

Synonym: PM0985

Alternate gene names: 15602850

Gene position: 1155241-1155966 (Clockwise)

Preceding gene: 15602849

Following gene: 15602852

Centisome position: 51.17

GC content: 41.32

Gene sequence:

>726_bases
ATGACAAAAGATACTCTATTTTCGACTCCCATTGCTAAATTGGGGGATTTTACTTTTGATGAAAGCGTAGCTGAAGTCTT
TCCCGACATGATCCAACGCTCTATTCCCGGCTATGCCAACATCATTACCGCTATTGGGATGTTGGCATCACGCTTTGTTA
CGGCGAATAGCAACGTCTATGATCTGGGGTGCTCGCGCGGTGCAGCAACATTATCTGCACGTCGTCATATTAATCAGCCC
GGCGTCAAGATCATTGGTGTTGATAACTCACAACCCATGGTCGATCGTTGTCGCCAGCATGTTAGTGCCTATCAAAGTAC
AATACCTGTGGACATTATTTGTGATGATATACGCCATATCGAAATCGAAAATGCCTCTATGGTAATTTTAAATTTCACTT
TGCAATTTCTGCCACCTGAAGATCGTCGATCCTTATTAAGTAAGATTTACCAAGGCTTACAACCGAATGGGATCTTGGTA
CTATCCGAGAAATTTCATTTTGAAGATCAAAACATGAATGCCTTGTTGATTGATTTACATCATCAATTTAAACGCGCGAA
TGGATACAGTGAACTTGAAGTCAGCCAAAAACGCACCGCACTTGAAAATGTGATGCGTACAGACAGCATTCAAGCCCATA
AAATGCGTTTAGCCGAAGTCGGTTTTCAACAAGTGGAATTATGGTTTCAATGCTTTAATTTTGGCTCAATGATTGCAGTG
AAGTAA

Upstream 100 bases:

>100_bases
AAAGTGCCATGGCGCATTTATTCCCGAAATCATAATTTATTTGTGATAGGTCGAAACTTCTTCTAAAATGACCGCACTTT
TTCTCGGTCTTTAATACATT

Downstream 100 bases:

>100_bases
GTGGCATACAACATAAAGGCGGTTCACTACCGCCTTTTGTTTTATAATGCTTTTAAATTTTTATCTAGTAAGCGGAACAA
CAACGCTTTTCCCCCTTTAA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 241; Mature: 240

Protein sequence:

>241_residues
MTKDTLFSTPIAKLGDFTFDESVAEVFPDMIQRSIPGYANIITAIGMLASRFVTANSNVYDLGCSRGAATLSARRHINQP
GVKIIGVDNSQPMVDRCRQHVSAYQSTIPVDIICDDIRHIEIENASMVILNFTLQFLPPEDRRSLLSKIYQGLQPNGILV
LSEKFHFEDQNMNALLIDLHHQFKRANGYSELEVSQKRTALENVMRTDSIQAHKMRLAEVGFQQVELWFQCFNFGSMIAV
K

Sequences:

>Translated_241_residues
MTKDTLFSTPIAKLGDFTFDESVAEVFPDMIQRSIPGYANIITAIGMLASRFVTANSNVYDLGCSRGAATLSARRHINQP
GVKIIGVDNSQPMVDRCRQHVSAYQSTIPVDIICDDIRHIEIENASMVILNFTLQFLPPEDRRSLLSKIYQGLQPNGILV
LSEKFHFEDQNMNALLIDLHHQFKRANGYSELEVSQKRTALENVMRTDSIQAHKMRLAEVGFQQVELWFQCFNFGSMIAV
K
>Mature_240_residues
TKDTLFSTPIAKLGDFTFDESVAEVFPDMIQRSIPGYANIITAIGMLASRFVTANSNVYDLGCSRGAATLSARRHINQPG
VKIIGVDNSQPMVDRCRQHVSAYQSTIPVDIICDDIRHIEIENASMVILNFTLQFLPPEDRRSLLSKIYQGLQPNGILVL
SEKFHFEDQNMNALLIDLHHQFKRANGYSELEVSQKRTALENVMRTDSIQAHKMRLAEVGFQQVELWFQCFNFGSMIAVK

Specific function: Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U)

COG id: COG0500

COG function: function code QR; SAM-dependent methyltransferases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. CmoA family

Homologues:

Organism=Escherichia coli, GI1788177, Length=239, Percent_Identity=67.3640167364017, Blast_Score=351, Evalue=2e-98,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CMOA_PASMU (Q9CM57)

Other databases:

- EMBL:   AE004439
- RefSeq:   NP_245922.1
- HSSP:   P43985
- ProteinModelPortal:   Q9CM57
- SMR:   Q9CM57
- GeneID:   1244332
- GenomeReviews:   AE004439_GR
- KEGG:   pmu:PM0985
- NMPDR:   fig|272843.1.peg.985
- HOGENOM:   HBG296860
- OMA:   YSELEVS
- ProtClustDB:   CLSK870321
- BioCyc:   PMUL272843:PM0985-MONOMER
- HAMAP:   MF_01589
- InterPro:   IPR013216
- InterPro:   IPR005271
- PIRSF:   PIRSF006325
- TIGRFAMs:   TIGR00740

Pfam domain/function: PF08241 Methyltransf_11

EC number: NA

Molecular weight: Translated: 27213; Mature: 27081

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: NA

Important sites: BINDING 38-38 BINDING 88-88 BINDING 131-131 BINDING 198-198

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKDTLFSTPIAKLGDFTFDESVAEVFPDMIQRSIPGYANIITAIGMLASRFVTANSNVY
CCCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHEECCCCEE
DLGCSRGAATLSARRHINQPGVKIIGVDNSQPMVDRCRQHVSAYQSTIPVDIICDDIRHI
ECCCCCCHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCHHEEECCCEEE
EIENASMVILNFTLQFLPPEDRRSLLSKIYQGLQPNGILVLSEKFHFEDQNMNALLIDLH
EECCCCEEEEEEEEEECCCHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCEEEEEHH
HQFKRANGYSELEVSQKRTALENVMRTDSIQAHKMRLAEVGFQQVELWFQCFNFGSMIAV
HHHHHCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEE
K
C
>Mature Secondary Structure 
TKDTLFSTPIAKLGDFTFDESVAEVFPDMIQRSIPGYANIITAIGMLASRFVTANSNVY
CCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHEECCCCEE
DLGCSRGAATLSARRHINQPGVKIIGVDNSQPMVDRCRQHVSAYQSTIPVDIICDDIRHI
ECCCCCCHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCHHEEECCCEEE
EIENASMVILNFTLQFLPPEDRRSLLSKIYQGLQPNGILVLSEKFHFEDQNMNALLIDLH
EECCCCEEEEEEEEEECCCHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCEEEEEHH
HQFKRANGYSELEVSQKRTALENVMRTDSIQAHKMRLAEVGFQQVELWFQCFNFGSMIAV
HHHHHCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEE
K
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11248100