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The map label for this gene is sotB

Identifier: 15602814

GI number: 15602814

Start: 1120303

End: 1121517

Strand: Reverse

Name: sotB

Synonym: PM0949

Alternate gene names: 15602814

Gene position: 1121517-1120303 (Counterclockwise)

Preceding gene: 15602815

Following gene: 15602813

Centisome position: 49.68

GC content: 40.33

Gene sequence:

>1215_bases
ATGTTACCTTTTCAGGCCGCTCGTCAACGTCAATTTGCGCGTGTTATCACCTTTGCGCTTGCTGGGTTTGTGTTTAATAC
AACAGAGTTTATTCCTGTTGCCTTACTCTCTGATATTGCGCAAAGCTTTGCGATGCCCGTATCACAAACGGGTTTAATAA
TTACTGTTTATGCTTGGGTAGTGTCATTAATGTCATTGCCTTTTATGTTACTGACTGCAAAAGCAGAGCGTAGAGGGTTA
TTGATTAAATTACTGGTGTTATTTATTTTAAGTCATCTGTTATCGGTGATCGCTTGGGATTTTTGGGTATTAGTATTAGC
CAGAATAGGTGTCGCATTAACCCATTCTATTTTTTGGGCAATTACTGCGTCTTTAGTCATTCGGGTTGCGCCTAAAGATA
AAAAATCACAGGCAATTGGACTACTTGCTATAGGTTGTTCTTTGGCAATGATTTTAGGCTTGCCCCTCGGACGTTTGATT
GGGCAATTCTTTGGTTGGCGTGCAACCTTTGCCATTATTGCCCTTATTGCGATAGGCATTTTATGCTTGTTTTATCAACT
TTTACCGCACTTACCAAGTAAGAATGCGGGTTCTTTAAATAGTCTGCCAACGCTTTTTAAACGTCCATTATTGCTTGGGC
TTTATGCGCTTACTATGATTATTATTTCGGCTCATTTTACTGCGTATAGCTATATTGAACCCTTTATGCTCAATATCAGC
ACAATGAGTCATAGTATGGCAACTTTTGTTCTCTTCGTCTTCGGTCTTTCTGGCATTACCGCTAGTTTGTTATTTAATCG
CTATTATAATGCAGGACCGATCCGTTTTATTTTGTTTTCAATGGGACTACTCACCGCTACACTTTTGCTCTTATTCATTG
CGAGCCAACAAACGTGGACAATGTTTTTATTAACCTTCTTCTGGGGAATTGGCATAGCAGGCATTGGCTTAGGATTACAA
ATTCGAGTGTTACACCTTGCCCCTGATGCTACAGACGTCGCGATGGCAATCTATTCTGGGATTTATAATATTGGCATTGG
GGCTGGCGCATTGCTAGGTAATCAAGTGATGCAACATTATGGGCTAGCCTATATTGGTGTTGCTGGGGCGTTATTTGCAG
TATTCGGGCTTGTTTTATTTATTTTAGTCCAGTGGAAATATGGTCACTTAGCGCCAAATAAGCTATCGACTGAAGAGAAG
AAAAAGTGCGGTTAA

Upstream 100 bases:

>100_bases
CTTTTTCGACAGTTGTTCTTCTCCGCAATATAAAGTGGAATTTAATCAGAATTTACGTCATCAATTAAAAGATCTTATTA
AAGAAAAATTGAGGTAATTT

Downstream 100 bases:

>100_bases
TATGAATCATATTATTGAATGGCGGTGAGAGAGGGATTCGAACCCTCGATACACTTTCGCATATACACGCTTTCCAGGCG
TGCTCCTTCAACCACTCGGA

Product: sugar efflux transporter

Products: arabinose [Periplasm]; Proton [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 404; Mature: 404

Protein sequence:

>404_residues
MLPFQAARQRQFARVITFALAGFVFNTTEFIPVALLSDIAQSFAMPVSQTGLIITVYAWVVSLMSLPFMLLTAKAERRGL
LIKLLVLFILSHLLSVIAWDFWVLVLARIGVALTHSIFWAITASLVIRVAPKDKKSQAIGLLAIGCSLAMILGLPLGRLI
GQFFGWRATFAIIALIAIGILCLFYQLLPHLPSKNAGSLNSLPTLFKRPLLLGLYALTMIIISAHFTAYSYIEPFMLNIS
TMSHSMATFVLFVFGLSGITASLLFNRYYNAGPIRFILFSMGLLTATLLLLFIASQQTWTMFLLTFFWGIGIAGIGLGLQ
IRVLHLAPDATDVAMAIYSGIYNIGIGAGALLGNQVMQHYGLAYIGVAGALFAVFGLVLFILVQWKYGHLAPNKLSTEEK
KKCG

Sequences:

>Translated_404_residues
MLPFQAARQRQFARVITFALAGFVFNTTEFIPVALLSDIAQSFAMPVSQTGLIITVYAWVVSLMSLPFMLLTAKAERRGL
LIKLLVLFILSHLLSVIAWDFWVLVLARIGVALTHSIFWAITASLVIRVAPKDKKSQAIGLLAIGCSLAMILGLPLGRLI
GQFFGWRATFAIIALIAIGILCLFYQLLPHLPSKNAGSLNSLPTLFKRPLLLGLYALTMIIISAHFTAYSYIEPFMLNIS
TMSHSMATFVLFVFGLSGITASLLFNRYYNAGPIRFILFSMGLLTATLLLLFIASQQTWTMFLLTFFWGIGIAGIGLGLQ
IRVLHLAPDATDVAMAIYSGIYNIGIGAGALLGNQVMQHYGLAYIGVAGALFAVFGLVLFILVQWKYGHLAPNKLSTEEK
KKCG
>Mature_404_residues
MLPFQAARQRQFARVITFALAGFVFNTTEFIPVALLSDIAQSFAMPVSQTGLIITVYAWVVSLMSLPFMLLTAKAERRGL
LIKLLVLFILSHLLSVIAWDFWVLVLARIGVALTHSIFWAITASLVIRVAPKDKKSQAIGLLAIGCSLAMILGLPLGRLI
GQFFGWRATFAIIALIAIGILCLFYQLLPHLPSKNAGSLNSLPTLFKRPLLLGLYALTMIIISAHFTAYSYIEPFMLNIS
TMSHSMATFVLFVFGLSGITASLLFNRYYNAGPIRFILFSMGLLTATLLLLFIASQQTWTMFLLTFFWGIGIAGIGLGLQ
IRVLHLAPDATDVAMAIYSGIYNIGIGAGALLGNQVMQHYGLAYIGVAGALFAVFGLVLFILVQWKYGHLAPNKLSTEEK
KKCG

Specific function: Involved in the efflux of sugars. The physiological role may be the reduction of the intracellular concentration of toxic sugars or sugar metabolites

COG id: COG2814

COG function: function code G; Arabinose efflux permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. SotB (TC 2.A.1.2) family

Homologues:

Organism=Escherichia coli, GI1787808, Length=377, Percent_Identity=53.5809018567639, Blast_Score=364, Evalue=1e-102,
Organism=Escherichia coli, GI1787947, Length=339, Percent_Identity=29.4985250737463, Blast_Score=115, Evalue=6e-27,
Organism=Escherichia coli, GI1786595, Length=355, Percent_Identity=24.7887323943662, Blast_Score=108, Evalue=6e-25,
Organism=Escherichia coli, GI145693198, Length=339, Percent_Identity=27.7286135693215, Blast_Score=108, Evalue=7e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SOTB_PASMU (Q9CM87)

Other databases:

- EMBL:   AE004439
- RefSeq:   NP_245886.1
- ProteinModelPortal:   Q9CM87
- GeneID:   1244296
- GenomeReviews:   AE004439_GR
- KEGG:   pmu:PM0949
- NMPDR:   fig|272843.1.peg.949
- HOGENOM:   HBG732715
- OMA:   NISTMSH
- ProtClustDB:   PRK03545
- BioCyc:   PMUL272843:PM0949-MONOMER
- HAMAP:   MF_00517
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196

Pfam domain/function: PF07690 MFS_1; SSF103473 MFS_gen_substrate_transporter

EC number: NA

Molecular weight: Translated: 44208; Mature: 44208

Theoretical pI: Translated: 10.36; Mature: 10.36

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xc331614)-; HASH(0xc9a9a74)-; HASH(0xde7c564)-; HASH(0xd27ed30)-; HASH(0xca45aa0)-; HASH(0xd9bf9ac)-; HASH(0xd1418ec)-; HASH(0xd2b2720)-; HASH(0xc52c4ac)-; HASH(0xd8bfaf4)-; HASH(0xcb5cd70)-; HASH(0xd97f2c4)-;

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLPFQAARQRQFARVITFALAGFVFNTTEFIPVALLSDIAQSFAMPVSQTGLIITVYAWV
CCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHH
VSLMSLPFMLLTAKAERRGLLIKLLVLFILSHLLSVIAWDFWVLVLARIGVALTHSIFWA
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ITASLVIRVAPKDKKSQAIGLLAIGCSLAMILGLPLGRLIGQFFGWRATFAIIALIAIGI
HHHHHHHEECCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
LCLFYQLLPHLPSKNAGSLNSLPTLFKRPLLLGLYALTMIIISAHFTAYSYIEPFMLNIS
HHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TMSHSMATFVLFVFGLSGITASLLFNRYYNAGPIRFILFSMGLLTATLLLLFIASQQTWT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHH
MFLLTFFWGIGIAGIGLGLQIRVLHLAPDATDVAMAIYSGIYNIGIGAGALLGNQVMQHY
HHHHHHHHHHHHHHHCCCEEEEEEEECCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
GLAYIGVAGALFAVFGLVLFILVQWKYGHLAPNKLSTEEKKKCG
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCH
>Mature Secondary Structure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CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: arabinose [Cytoplasm]; Proton [Periplasm] [C]

Specific reaction: arabinose [Cytoplasm] + Proton [Periplasm] = arabinose [Periplasm] + Proton [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11248100