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The map label for this gene is cpg2 [H]

Identifier: 15602797

GI number: 15602797

Start: 1099957

End: 1101096

Strand: Direct

Name: cpg2 [H]

Synonym: PM0932

Alternate gene names: 15602797

Gene position: 1099957-1101096 (Clockwise)

Preceding gene: 15602796

Following gene: 15602798

Centisome position: 48.72

GC content: 41.75

Gene sequence:

>1140_bases
ATGATATTAAATGCCTTTCTGAAAGATCTAGAATCTCTCGTCAATATTGATAGCTATAGCTATGATCCTGTTGGTAAAGC
ACGTGTTGTCCAATTTTTTAAAGAAAAATTCCAGTCCATTGGTTGGCTTGTAGAAGAACGTTTTCTTGATGAAAAAGTGG
GCTCTGCGCTGATTTGTAAAAATACGCCTTCTGATACATTTGATGTGGTTTTATCAGGACATATGGATACCGTGTTTAAA
ACTGGAACAGTCAATGAACGCCCATTTAGAATTGAGCAAGATAAAGCTTTTGGACCGGGAATTGCTGATATGAAAGCCGG
TCTCTTAGCTGGATTTTACGCTTGTAAACAGTTAACTGAAGAAAATGCGCTACAAGATGCAAAAGTCTGCGTGCTTTTCA
ATCCCGATGAAGAAATTAGTTCTATCTTCTCTCGCCCATTGTTAGAGGACTATGCGAAAAAAACACGCTATGCCATTATT
CTAGAAGCCGCCAGAATTAACGGTAACCTAGTCAACGAAAGAAAAGGGATTGGAAAGTACGTAATTGAATTTTTTGGCAA
ATCTGCTCACGCGGCAGTCGATCCACAAAACGGAGCAAATGCCATCAATGCGTTTATTCGTATCGCGCAAGATTTACTAA
AAAGTACCGCACCCGACAAAGGTACCACAATGAACATTGGTACTGTTGAAGGAGGGACCACGCCAAATACTGTACCTGAC
TATGTCAAAACACAAATTGATTGTCGCTTTACTTGTCTTGAAGAAAGTCAACGACTCAATCAACTTATTTACGCCCTAAA
TGACACTGTGACCGAAGAACGCGTCAAAATCAAAGTAACAGGGGGCATTACTCGTCCACCTTGGCGACGTACTGAAGCCG
GTCTTCAATTCTGCGCCGCTGTCGATAAAATCAAAGAAAAACTCGGCATACAAGCTGAATGGGAATCCACTGCTGGGGGG
TCTGATGGGAATTTCTTTGCTGCACTCGGTGTCACTGTCATTGATGGCATGGGACCAAGCGGTGGAAAATGGCACAGTCC
TGATGAATACTTAAATATCGACTCCATCGAACCGAGAGTCAAACTCGTATCTGAAGTCATAAAATATTGTACTCAACATA
AAGGAGGCACGTCATGCTAG

Upstream 100 bases:

>100_bases
TATTTTCTGACCGAATATGTCACTATGCCTATTGAGTAATATTGTGCTGTTTGCTTTTTAATTTGATTTTACATAAGTCA
TAAATAAGAAGGAAAAGTCT

Downstream 100 bases:

>100_bases
GACTACTGCTTGGATTAGCGGTAACCATTCTTGTTGGTTATCTCATTGTCAAAAAGTACAAAGCACAATTTGTGTTACTG
TGTGGTGGTATTATCTTGAT

Product: hypothetical protein

Products: NA

Alternate protein names: CPDG2; Folate hydrolase G2; Glutamate carboxypeptidase; Pteroylmonoglutamic acid hydrolase G2; Glucarpidase [H]

Number of amino acids: Translated: 379; Mature: 379

Protein sequence:

>379_residues
MILNAFLKDLESLVNIDSYSYDPVGKARVVQFFKEKFQSIGWLVEERFLDEKVGSALICKNTPSDTFDVVLSGHMDTVFK
TGTVNERPFRIEQDKAFGPGIADMKAGLLAGFYACKQLTEENALQDAKVCVLFNPDEEISSIFSRPLLEDYAKKTRYAII
LEAARINGNLVNERKGIGKYVIEFFGKSAHAAVDPQNGANAINAFIRIAQDLLKSTAPDKGTTMNIGTVEGGTTPNTVPD
YVKTQIDCRFTCLEESQRLNQLIYALNDTVTEERVKIKVTGGITRPPWRRTEAGLQFCAAVDKIKEKLGIQAEWESTAGG
SDGNFFAALGVTVIDGMGPSGGKWHSPDEYLNIDSIEPRVKLVSEVIKYCTQHKGGTSC

Sequences:

>Translated_379_residues
MILNAFLKDLESLVNIDSYSYDPVGKARVVQFFKEKFQSIGWLVEERFLDEKVGSALICKNTPSDTFDVVLSGHMDTVFK
TGTVNERPFRIEQDKAFGPGIADMKAGLLAGFYACKQLTEENALQDAKVCVLFNPDEEISSIFSRPLLEDYAKKTRYAII
LEAARINGNLVNERKGIGKYVIEFFGKSAHAAVDPQNGANAINAFIRIAQDLLKSTAPDKGTTMNIGTVEGGTTPNTVPD
YVKTQIDCRFTCLEESQRLNQLIYALNDTVTEERVKIKVTGGITRPPWRRTEAGLQFCAAVDKIKEKLGIQAEWESTAGG
SDGNFFAALGVTVIDGMGPSGGKWHSPDEYLNIDSIEPRVKLVSEVIKYCTQHKGGTSC
>Mature_379_residues
MILNAFLKDLESLVNIDSYSYDPVGKARVVQFFKEKFQSIGWLVEERFLDEKVGSALICKNTPSDTFDVVLSGHMDTVFK
TGTVNERPFRIEQDKAFGPGIADMKAGLLAGFYACKQLTEENALQDAKVCVLFNPDEEISSIFSRPLLEDYAKKTRYAII
LEAARINGNLVNERKGIGKYVIEFFGKSAHAAVDPQNGANAINAFIRIAQDLLKSTAPDKGTTMNIGTVEGGTTPNTVPD
YVKTQIDCRFTCLEESQRLNQLIYALNDTVTEERVKIKVTGGITRPPWRRTEAGLQFCAAVDKIKEKLGIQAEWESTAGG
SDGNFFAALGVTVIDGMGPSGGKWHSPDEYLNIDSIEPRVKLVSEVIKYCTQHKGGTSC

Specific function: Catalyzes the hydrolysis of reduced and non-reduced folates to pteroates and L-glutamate. This enzyme has a broad specificity [H]

COG id: COG0624

COG function: function code E; Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20A family [H]

Homologues:

Organism=Escherichia coli, GI1790395, Length=374, Percent_Identity=28.8770053475936, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1788816, Length=378, Percent_Identity=23.2804232804233, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001261
- InterPro:   IPR017150
- InterPro:   IPR002933
- InterPro:   IPR011650 [H]

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20 [H]

EC number: =3.4.17.11 [H]

Molecular weight: Translated: 41746; Mature: 41746

Theoretical pI: Translated: 5.34; Mature: 5.34

Prosite motif: PS00759 ARGE_DAPE_CPG2_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILNAFLKDLESLVNIDSYSYDPVGKARVVQFFKEKFQSIGWLVEERFLDEKVGSALICK
CCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEC
NTPSDTFDVVLSGHMDTVFKTGTVNERPFRIEQDKAFGPGIADMKAGLLAGFYACKQLTE
CCCCCCCHHEEECCHHHHEECCCCCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHH
ENALQDAKVCVLFNPDEEISSIFSRPLLEDYAKKTRYAIILEAARINGNLVNERKGIGKY
HHCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHCEEEEEEEEECCCCCCCHHHHHHHHH
VIEFFGKSAHAAVDPQNGANAINAFIRIAQDLLKSTAPDKGTTMNIGTVEGGTTPNTVPD
HHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCHH
YVKTQIDCRFTCLEESQRLNQLIYALNDTVTEERVKIKVTGGITRPPWRRTEAGLQFCAA
HHHHHHCEEEEHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHH
VDKIKEKLGIQAEWESTAGGSDGNFFAALGVTVIDGMGPSGGKWHSPDEYLNIDSIEPRV
HHHHHHHHCCCEECCCCCCCCCCCEEEEEHHHHCCCCCCCCCCCCCCHHCCCCCCCCHHH
KLVSEVIKYCTQHKGGTSC
HHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MILNAFLKDLESLVNIDSYSYDPVGKARVVQFFKEKFQSIGWLVEERFLDEKVGSALICK
CCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEC
NTPSDTFDVVLSGHMDTVFKTGTVNERPFRIEQDKAFGPGIADMKAGLLAGFYACKQLTE
CCCCCCCHHEEECCHHHHEECCCCCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHH
ENALQDAKVCVLFNPDEEISSIFSRPLLEDYAKKTRYAIILEAARINGNLVNERKGIGKY
HHCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHCEEEEEEEEECCCCCCCHHHHHHHHH
VIEFFGKSAHAAVDPQNGANAINAFIRIAQDLLKSTAPDKGTTMNIGTVEGGTTPNTVPD
HHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCHH
YVKTQIDCRFTCLEESQRLNQLIYALNDTVTEERVKIKVTGGITRPPWRRTEAGLQFCAA
HHHHHHCEEEEHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHH
VDKIKEKLGIQAEWESTAGGSDGNFFAALGVTVIDGMGPSGGKWHSPDEYLNIDSIEPRV
HHHHHHHHCCCEECCCCCCCCCCCEEEEEHHHHCCCCCCCCCCCCCCHHCCCCCCCCHHH
KLVSEVIKYCTQHKGGTSC
HHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 6396165; 3838935; 9083113 [H]