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The map label for this gene is gapdH [H]

Identifier: 15602789

GI number: 15602789

Start: 1089501

End: 1090505

Strand: Direct

Name: gapdH [H]

Synonym: PM0924

Alternate gene names: 15602789

Gene position: 1089501-1090505 (Clockwise)

Preceding gene: 15602780

Following gene: 15602790

Centisome position: 48.26

GC content: 40.9

Gene sequence:

>1005_bases
ATGGCAATTAAAATTGGTATCAACGGCTTTGGCCGTATCGGTCGTATCGTATTTCGTGCTGCACAACATCGTGATGACAT
CGAAGTAGTCGGTATCAACGACTTAATCGATGTTGAATATATGGCTTATATGCTTAAATACGATTCAACTCATGGTCGTT
TCGATGGTACTGTTGAAGTAAAAGATGGCAACTTAGTGGTAAATGGTAAAACTATCCGTGTCACTGCTGAGCGTGATCCA
GCTAACTTAAAATGGAACGAAATCGGTGTGGAAATTGCCGTTGAAGCGACTGGTTTATTCTTAGATGATGCAACTGCACG
TAAACACATTACTGCTGGTGCGAAAAAAGTCGTATTAACTGGTCCATCTAAAGATGCTACTCCAATGTTTGTCAGCGGTG
TAAACTTTGACACTTATGCAGGTCAAGATATCGTGTCTAACGCCTCTTGTACAACAAACTGCTTAGCACCATTAGCGAAA
GTGATCAACGACAAATTTGGTATCAAAGACGGTTTAATGACAACAGTTCACGCAACGACTGCAACGCAAAAAACTGTTGA
TGGTCCATCTGCAAAAGACTGGCGTGGTGGCCGTGGTGCGGCACAAAACATCATCCCATCATCAACAGGTGCAGCGAAAG
CAGTAGGTAAAGTTATCCCTGCATTAAATGGTAAATTAACGGGTATGGCGTTCCGTGTTCCTACACCAAACGTATCTGTT
GTTGACTTAACTGTTAACTTAGAAAAACCAGCAACTTATGCTGAAATCTGTGCAGAAATCAAACGCGCATCTGAAAACGA
AATGAAAGGTGTGTTAGGTTACACTGAAGATGCTGTTGTTTCTACAGACTTCAATGGTTGTGCATTAACATCTGTATTTG
ATGCAGCAGCAGGTATTGCATTAACCGATACATTCGTGAAATTAGTTTCTTGGTATGATAACGAAACCGGCTACTCAAAC
AAAGTATTAGACTTAGTCGCACACGTTTATAACTACAAAGGTTAA

Upstream 100 bases:

>100_bases
AAACCGTGCTATAATCCTCCGCGACAAAAACAAAAATGAAACACACCATTTTTGTTCTCTGTAACCGTTTTGTTTAACTT
TAAATATAGGTGAAAATCTT

Downstream 100 bases:

>100_bases
TTACTAACCTAAATAAACACGAAGCCTCTTGTCAGAACAAGGGGCTTCTTTTTTGCTGTCAACAAAAACGAAAAGCTGGA
TTTTATAAGAAAACCCAGCT

Product: glyceraldehyde-3-phosphate dehydrogenase

Products: NA

Alternate protein names: GAPDH [H]

Number of amino acids: Translated: 334; Mature: 333

Protein sequence:

>334_residues
MAIKIGINGFGRIGRIVFRAAQHRDDIEVVGINDLIDVEYMAYMLKYDSTHGRFDGTVEVKDGNLVVNGKTIRVTAERDP
ANLKWNEIGVEIAVEATGLFLDDATARKHITAGAKKVVLTGPSKDATPMFVSGVNFDTYAGQDIVSNASCTTNCLAPLAK
VINDKFGIKDGLMTTVHATTATQKTVDGPSAKDWRGGRGAAQNIIPSSTGAAKAVGKVIPALNGKLTGMAFRVPTPNVSV
VDLTVNLEKPATYAEICAEIKRASENEMKGVLGYTEDAVVSTDFNGCALTSVFDAAAGIALTDTFVKLVSWYDNETGYSN
KVLDLVAHVYNYKG

Sequences:

>Translated_334_residues
MAIKIGINGFGRIGRIVFRAAQHRDDIEVVGINDLIDVEYMAYMLKYDSTHGRFDGTVEVKDGNLVVNGKTIRVTAERDP
ANLKWNEIGVEIAVEATGLFLDDATARKHITAGAKKVVLTGPSKDATPMFVSGVNFDTYAGQDIVSNASCTTNCLAPLAK
VINDKFGIKDGLMTTVHATTATQKTVDGPSAKDWRGGRGAAQNIIPSSTGAAKAVGKVIPALNGKLTGMAFRVPTPNVSV
VDLTVNLEKPATYAEICAEIKRASENEMKGVLGYTEDAVVSTDFNGCALTSVFDAAAGIALTDTFVKLVSWYDNETGYSN
KVLDLVAHVYNYKG
>Mature_333_residues
AIKIGINGFGRIGRIVFRAAQHRDDIEVVGINDLIDVEYMAYMLKYDSTHGRFDGTVEVKDGNLVVNGKTIRVTAERDPA
NLKWNEIGVEIAVEATGLFLDDATARKHITAGAKKVVLTGPSKDATPMFVSGVNFDTYAGQDIVSNASCTTNCLAPLAKV
INDKFGIKDGLMTTVHATTATQKTVDGPSAKDWRGGRGAAQNIIPSSTGAAKAVGKVIPALNGKLTGMAFRVPTPNVSVV
DLTVNLEKPATYAEICAEIKRASENEMKGVLGYTEDAVVSTDFNGCALTSVFDAAAGIALTDTFVKLVSWYDNETGYSNK
VLDLVAHVYNYKG

Specific function: Second phase of glycolysis; first step. [C]

COG id: COG0057

COG function: function code G; Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI7669492, Length=329, Percent_Identity=64.4376899696049, Blast_Score=432, Evalue=1e-121,
Organism=Homo sapiens, GI7657116, Length=332, Percent_Identity=60.5421686746988, Blast_Score=407, Evalue=1e-114,
Organism=Escherichia coli, GI1788079, Length=329, Percent_Identity=84.4984802431611, Blast_Score=577, Evalue=1e-166,
Organism=Escherichia coli, GI1789295, Length=329, Percent_Identity=39.5136778115502, Blast_Score=244, Evalue=6e-66,
Organism=Caenorhabditis elegans, GI32566163, Length=333, Percent_Identity=62.4624624624625, Blast_Score=407, Evalue=1e-114,
Organism=Caenorhabditis elegans, GI17568413, Length=333, Percent_Identity=62.4624624624625, Blast_Score=407, Evalue=1e-114,
Organism=Caenorhabditis elegans, GI17534677, Length=334, Percent_Identity=61.0778443113772, Blast_Score=402, Evalue=1e-112,
Organism=Caenorhabditis elegans, GI17534679, Length=334, Percent_Identity=60.4790419161677, Blast_Score=400, Evalue=1e-112,
Organism=Saccharomyces cerevisiae, GI6322409, Length=329, Percent_Identity=66.2613981762918, Blast_Score=433, Evalue=1e-122,
Organism=Saccharomyces cerevisiae, GI6322468, Length=329, Percent_Identity=65.6534954407295, Blast_Score=429, Evalue=1e-121,
Organism=Saccharomyces cerevisiae, GI6321631, Length=329, Percent_Identity=65.9574468085106, Blast_Score=428, Evalue=1e-121,
Organism=Drosophila melanogaster, GI85725000, Length=328, Percent_Identity=67.0731707317073, Blast_Score=431, Evalue=1e-121,
Organism=Drosophila melanogaster, GI22023983, Length=328, Percent_Identity=67.0731707317073, Blast_Score=431, Evalue=1e-121,
Organism=Drosophila melanogaster, GI17933600, Length=328, Percent_Identity=66.7682926829268, Blast_Score=427, Evalue=1e-120,
Organism=Drosophila melanogaster, GI18110149, Length=328, Percent_Identity=66.7682926829268, Blast_Score=427, Evalue=1e-120,
Organism=Drosophila melanogaster, GI19922412, Length=326, Percent_Identity=62.8834355828221, Blast_Score=408, Evalue=1e-114,

Paralogues:

None

Copy number: 220 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 740 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1660 Molecules/Cell In: Growth Phase, Min

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020831
- InterPro:   IPR020830
- InterPro:   IPR020829
- InterPro:   IPR020828
- InterPro:   IPR006424
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02800 Gp_dh_C; PF00044 Gp_dh_N [H]

EC number: =1.2.1.12 [H]

Molecular weight: Translated: 35618; Mature: 35487

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: PS00071 GAPDH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIKIGINGFGRIGRIVFRAAQHRDDIEVVGINDLIDVEYMAYMLKYDSTHGRFDGTVEV
CEEEEECCCCCHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHCCCCCCCCCCEEEE
KDGNLVVNGKTIRVTAERDPANLKWNEIGVEIAVEATGLFLDDATARKHITAGAKKVVLT
ECCCEEECCEEEEEEECCCCCCCEEEEECEEEEEEEEEEEEECCHHHHHHCCCCCEEEEE
GPSKDATPMFVSGVNFDTYAGQDIVSNASCTTNCLAPLAKVINDKFGIKDGLMTTVHATT
CCCCCCCCEEEECCCCCCCCCCHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEEECC
ATQKTVDGPSAKDWRGGRGAAQNIIPSSTGAAKAVGKVIPALNGKLTGMAFRVPTPNVSV
CCCCCCCCCCCCCCCCCCCCHHCCCCCCCCHHHHHHHHHHCCCCCEEEEEEECCCCCCEE
VDLTVNLEKPATYAEICAEIKRASENEMKGVLGYTEDAVVSTDFNGCALTSVFDAAAGIA
EEEEEECCCCCHHHHHHHHHHHCCHHHHHHHCCCCCCCEEECCCCCEEHHHHHHHHCCCH
LTDTFVKLVSWYDNETGYSNKVLDLVAHVYNYKG
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCC
>Mature Secondary Structure 
AIKIGINGFGRIGRIVFRAAQHRDDIEVVGINDLIDVEYMAYMLKYDSTHGRFDGTVEV
EEEEECCCCCHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHCCCCCCCCCCEEEE
KDGNLVVNGKTIRVTAERDPANLKWNEIGVEIAVEATGLFLDDATARKHITAGAKKVVLT
ECCCEEECCEEEEEEECCCCCCCEEEEECEEEEEEEEEEEEECCHHHHHHCCCCCEEEEE
GPSKDATPMFVSGVNFDTYAGQDIVSNASCTTNCLAPLAKVINDKFGIKDGLMTTVHATT
CCCCCCCCEEEECCCCCCCCCCHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEEECC
ATQKTVDGPSAKDWRGGRGAAQNIIPSSTGAAKAVGKVIPALNGKLTGMAFRVPTPNVSV
CCCCCCCCCCCCCCCCCCCCHHCCCCCCCCHHHHHHHHHHCCCCCEEEEEEECCCCCCEE
VDLTVNLEKPATYAEICAEIKRASENEMKGVLGYTEDAVVSTDFNGCALTSVFDAAAGIA
EEEEEECCCCCHHHHHHHHHHHCCHHHHHHHCCCCCCCEEECCCCCEEHHHHHHHHCCCH
LTDTFVKLVSWYDNETGYSNKVLDLVAHVYNYKG
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]