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The map label for this gene is sapD [H]

Identifier: 15602779

GI number: 15602779

Start: 1073738

End: 1074787

Strand: Direct

Name: sapD [H]

Synonym: PM0914

Alternate gene names: 15602779

Gene position: 1073738-1074787 (Clockwise)

Preceding gene: 15602778

Following gene: 15602780

Centisome position: 47.56

GC content: 39.14

Gene sequence:

>1050_bases
ATGGCGCTATTAGATATTCGAAACCTGTGTATTGAAATTGAAACATCGCAAGGGCGTATCAAGGTTGTCGATAATGTCAA
TCTTACCCTTAACGAAGGCGAAATTTGTGGTTTAGTCGGAGAATCAGGTTCAGGAAAAAGCTTAATCGCAAAAGTAATTT
GTAATGTGTTTCGTGACTCTTGGATTGTCACCGCCGACCGTTTCCGTTTTGACAACATTGAATTACTAAAATTACCGCCC
AAAAAACGACGTAAATTAATTGGGCAAGAAATATCAATGATCTTCCAAGACCCACTGACTTGTTTAGACCCGAGCAAAAC
GATTGGCAAACAAATCATCCAGAATATCCCCTCATGGACATTTAAAGGTCGTTGGTGGCAGTGGTTTGGTTGGAAAAAAC
GTCGTGCAATCGAATTATTGCACAAAGTAGGCATTAAAGAACACGAGGATATCATGCAAAGTTATCCTGAAGAGATTACC
GAAGGTGAAGGACAAAAAGTCATGATCGCCATTGCCGTTGCGAATCAGCCTCGTTTACTCATTGCTGATGAGCCTACTAA
CTCTGTGGAATCAATCACTAAAGCTCAGATCTTTCGCTTACTCTCAAGTATGAACCAAAATCAAGGCACATCTATTTTAC
TGACCAGTAACGATATCAAGAGTATCAGTGAATGGTGTGATACATTTTCTGTACTTTACTGTGGACAAAATGCCGAATCT
GGACCAAAAGAAGAGATTTTAGAACACCCACATCATCCCTATACACAAGCCTTGTTACATTCGATTCCAGACTTTAGTCA
ACCATTACCCTTGAAAAGTCGCTTGAATACATTAAAAGGCACCGTTCCTTTATTAGAACAAATGCCAATTGGTTGTCGCC
TTGGACCAAGATGCCCCTTTGCGCAAAAAAAATGTATTGTAAAACCTACAAGGTATCGTATTAAACAGCATGAATTTTCC
TGTCACTACCCTTTAAATTTACGCGAAAAACAATTTAAAGAAAAACAGGTTAGCGCCCCTTTAATACTCCAAAATGCAAA
ATCAGAATAG

Upstream 100 bases:

>100_bases
ATTCTCCCCGGCATCGCCATTATTTTAACCATTTTAGTCGTTTTTATTTTCAGCCAAGGCCTGTGTAAAGCGATAGAGAA
ATATTACGAGTAGGTGAATC

Downstream 100 bases:

>100_bases
AAGGTAAAGAGAATGGCACTATTACAAGTTGAAGATCTGTCAAAATCTTTTACTGATACGATGAGCTTATTTGGCGCCAG
CCAATTTAATGCTGTAGAAA

Product: SapD

Products: ADP; phosphate; peptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 349; Mature: 348

Protein sequence:

>349_residues
MALLDIRNLCIEIETSQGRIKVVDNVNLTLNEGEICGLVGESGSGKSLIAKVICNVFRDSWIVTADRFRFDNIELLKLPP
KKRRKLIGQEISMIFQDPLTCLDPSKTIGKQIIQNIPSWTFKGRWWQWFGWKKRRAIELLHKVGIKEHEDIMQSYPEEIT
EGEGQKVMIAIAVANQPRLLIADEPTNSVESITKAQIFRLLSSMNQNQGTSILLTSNDIKSISEWCDTFSVLYCGQNAES
GPKEEILEHPHHPYTQALLHSIPDFSQPLPLKSRLNTLKGTVPLLEQMPIGCRLGPRCPFAQKKCIVKPTRYRIKQHEFS
CHYPLNLREKQFKEKQVSAPLILQNAKSE

Sequences:

>Translated_349_residues
MALLDIRNLCIEIETSQGRIKVVDNVNLTLNEGEICGLVGESGSGKSLIAKVICNVFRDSWIVTADRFRFDNIELLKLPP
KKRRKLIGQEISMIFQDPLTCLDPSKTIGKQIIQNIPSWTFKGRWWQWFGWKKRRAIELLHKVGIKEHEDIMQSYPEEIT
EGEGQKVMIAIAVANQPRLLIADEPTNSVESITKAQIFRLLSSMNQNQGTSILLTSNDIKSISEWCDTFSVLYCGQNAES
GPKEEILEHPHHPYTQALLHSIPDFSQPLPLKSRLNTLKGTVPLLEQMPIGCRLGPRCPFAQKKCIVKPTRYRIKQHEFS
CHYPLNLREKQFKEKQVSAPLILQNAKSE
>Mature_348_residues
ALLDIRNLCIEIETSQGRIKVVDNVNLTLNEGEICGLVGESGSGKSLIAKVICNVFRDSWIVTADRFRFDNIELLKLPPK
KRRKLIGQEISMIFQDPLTCLDPSKTIGKQIIQNIPSWTFKGRWWQWFGWKKRRAIELLHKVGIKEHEDIMQSYPEEITE
GEGQKVMIAIAVANQPRLLIADEPTNSVESITKAQIFRLLSSMNQNQGTSILLTSNDIKSISEWCDTFSVLYCGQNAESG
PKEEILEHPHHPYTQALLHSIPDFSQPLPLKSRLNTLKGTVPLLEQMPIGCRLGPRCPFAQKKCIVKPTRYRIKQHEFSC
HYPLNLREKQFKEKQVSAPLILQNAKSE

Specific function: Involved in a peptide intake transport system that plays a role in the resistance to antimicrobial peptides [H]

COG id: COG4170

COG function: function code V; ABC-type antimicrobial peptide transport system, ATPase component

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Escherichia coli, GI1787548, Length=330, Percent_Identity=64.5454545454545, Blast_Score=474, Evalue=1e-135,
Organism=Escherichia coli, GI1789963, Length=328, Percent_Identity=37.1951219512195, Blast_Score=240, Evalue=1e-64,
Organism=Escherichia coli, GI1787759, Length=306, Percent_Identity=36.2745098039216, Blast_Score=201, Evalue=6e-53,
Organism=Escherichia coli, GI48994883, Length=308, Percent_Identity=32.7922077922078, Blast_Score=188, Evalue=4e-49,
Organism=Escherichia coli, GI145693107, Length=285, Percent_Identity=32.280701754386, Blast_Score=162, Evalue=4e-41,
Organism=Escherichia coli, GI1787500, Length=330, Percent_Identity=31.2121212121212, Blast_Score=162, Evalue=4e-41,
Organism=Escherichia coli, GI1787758, Length=291, Percent_Identity=30.5841924398625, Blast_Score=143, Evalue=2e-35,
Organism=Escherichia coli, GI1789962, Length=280, Percent_Identity=30.7142857142857, Blast_Score=142, Evalue=3e-35,
Organism=Escherichia coli, GI1788506, Length=318, Percent_Identity=30.8176100628931, Blast_Score=141, Evalue=7e-35,
Organism=Escherichia coli, GI1786398, Length=273, Percent_Identity=29.3040293040293, Blast_Score=104, Evalue=1e-23,
Organism=Escherichia coli, GI1789890, Length=260, Percent_Identity=27.6923076923077, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1789891, Length=219, Percent_Identity=28.310502283105, Blast_Score=99, Evalue=6e-22,
Organism=Escherichia coli, GI1787547, Length=263, Percent_Identity=26.9961977186312, Blast_Score=98, Evalue=9e-22,
Organism=Escherichia coli, GI48994997, Length=260, Percent_Identity=26.5384615384615, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI87081834, Length=218, Percent_Identity=30.7339449541284, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI1789032, Length=253, Percent_Identity=24.901185770751, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI87081791, Length=269, Percent_Identity=24.5353159851301, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1789873, Length=211, Percent_Identity=31.7535545023697, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1787029, Length=246, Percent_Identity=26.4227642276423, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI1787370, Length=251, Percent_Identity=23.9043824701195, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1788450, Length=239, Percent_Identity=24.6861924686192, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI1788225, Length=261, Percent_Identity=24.904214559387, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1790544, Length=228, Percent_Identity=25, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1786703, Length=234, Percent_Identity=25.2136752136752, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1789672, Length=265, Percent_Identity=26.7924528301887, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI1789991, Length=237, Percent_Identity=28.2700421940928, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1789593, Length=254, Percent_Identity=28.3464566929134, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1790525, Length=237, Percent_Identity=28.6919831223629, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI48994943, Length=232, Percent_Identity=23.7068965517241, Blast_Score=72, Evalue=7e-14,
Organism=Escherichia coli, GI1787712, Length=246, Percent_Identity=23.1707317073171, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1790467, Length=245, Percent_Identity=22.0408163265306, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1790190, Length=232, Percent_Identity=27.1551724137931, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1786563, Length=218, Percent_Identity=26.1467889908257, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI87082267, Length=245, Percent_Identity=22.0408163265306, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1788644, Length=264, Percent_Identity=24.6212121212121, Blast_Score=62, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6324498, Length=254, Percent_Identity=23.2283464566929, Blast_Score=66, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24641565, Length=237, Percent_Identity=24.4725738396624, Blast_Score=68, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR003593
- InterPro:   IPR010066
- InterPro:   IPR013563 [H]

Pfam domain/function: PF00005 ABC_tran; PF08352 oligo_HPY [H]

EC number: NA

Molecular weight: Translated: 39796; Mature: 39665

Theoretical pI: Translated: 8.84; Mature: 8.84

Prosite motif: PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALLDIRNLCIEIETSQGRIKVVDNVNLTLNEGEICGLVGESGSGKSLIAKVICNVFRDS
CCCEEEECEEEEEECCCCEEEEEECCEEEECCCCEEEEECCCCCCHHHHHHHHHHHHHCC
WIVTADRFRFDNIELLKLPPKKRRKLIGQEISMIFQDPLTCLDPSKTIGKQIIQNIPSWT
EEEEECCEECCCEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCE
FKGRWWQWFGWKKRRAIELLHKVGIKEHEDIMQSYPEEITEGEGQKVMIAIAVANQPRLL
ECCCEEEECCHHHHHHHHHHHHCCCCHHHHHHHHCCHHHHCCCCCEEEEEEEECCCCEEE
IADEPTNSVESITKAQIFRLLSSMNQNQGTSILLTSNDIKSISEWCDTFSVLYCGQNAES
EECCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEECCHHHHHHHHHHHHEEEEECCCCCC
GPKEEILEHPHHPYTQALLHSIPDFSQPLPLKSRLNTLKGTVPLLEQMPIGCRLGPRCPF
CCHHHHHHCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHCCHHHHHCCCCCCCCCCCCCC
AQKKCIVKPTRYRIKQHEFSCHYPLNLREKQFKEKQVSAPLILQNAKSE
CCCCCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCEEECCCCCC
>Mature Secondary Structure 
ALLDIRNLCIEIETSQGRIKVVDNVNLTLNEGEICGLVGESGSGKSLIAKVICNVFRDS
CCEEEECEEEEEECCCCEEEEEECCEEEECCCCEEEEECCCCCCHHHHHHHHHHHHHCC
WIVTADRFRFDNIELLKLPPKKRRKLIGQEISMIFQDPLTCLDPSKTIGKQIIQNIPSWT
EEEEECCEECCCEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCE
FKGRWWQWFGWKKRRAIELLHKVGIKEHEDIMQSYPEEITEGEGQKVMIAIAVANQPRLL
ECCCEEEECCHHHHHHHHHHHHCCCCHHHHHHHHCCHHHHCCCCCEEEEEEEECCCCEEE
IADEPTNSVESITKAQIFRLLSSMNQNQGTSILLTSNDIKSISEWCDTFSVLYCGQNAES
EECCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEECCHHHHHHHHHHHHEEEEECCCCCC
GPKEEILEHPHHPYTQALLHSIPDFSQPLPLKSRLNTLKGTVPLLEQMPIGCRLGPRCPF
CCHHHHHHCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHCCHHHHHCCCCCCCCCCCCCC
AQKKCIVKPTRYRIKQHEFSCHYPLNLREKQFKEKQVSAPLILQNAKSE
CCCCCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; peptides [Periplasm]; H2O [C]

Specific reaction: ATP + peptides [Periplasm] + H2O = ADP + phosphate + peptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]