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The map label for this gene is sapB [H]

Identifier: 15602777

GI number: 15602777

Start: 1071888

End: 1072853

Strand: Direct

Name: sapB [H]

Synonym: PM0912

Alternate gene names: 15602777

Gene position: 1071888-1072853 (Clockwise)

Preceding gene: 15602776

Following gene: 15602778

Centisome position: 47.48

GC content: 40.06

Gene sequence:

>966_bases
ATGATCGTTGCTTTATTACGCCAAGTTTTCCTTGTGTTTCTGACATTACTGATTCTGTCTTTGCTCAGTTATATGATTTT
AATCCAAGACCCGCTGAATGAAGAACTAATGCAGCCAAGTCTCCTACAAGGCTATATCTCGCATATTACTCACTTACTAC
AAGGGGATTTTGGCATTACGTACAACGGAGGCGATTCACTGAATGCCATTATCCAAACCGTTTTACCGCCTACCCTCGAA
CTTTGCTTCAGCGCTATTTTACTTGCCGTATTATTTGGCATCCCATTAGGGCTCATGGGCGCAATGAAAAGCCACACTTT
TTTAGGGAAGGGAATTCGCACTATGTCTGCTTTAGGTTTATCTATGCCAGTATTTTGGATCGCACCTATTGCACTGTATT
TTTCTGCTATTCATAGTTGGGAAATTTCAGCGATCGGGCAATATAACTTACTTTATGCGATCAAACCAATCACTGGCTTT
CCTATTATTGATGTCTGGTTTATGGACGAATTTTACCGCACCAAAGTCATTCAGAATGTCCTACAGCATCTTGTCTTACC
CACTTTAGTGCTGACAATTTTGCCAACAATGGAGATCACAAGAATTGTGCAGCAACGGGCTGAAGATGTGTTAACGAAAA
ATTATATCAAGATGGCAATGACCCGGGGGTGGTCACAAAATAAGATCTTACGCAAACATGTTTTACGTAACACACTTCCA
CTATTAATTCCTCAATCGACACGTTTATTTACACTTGTCCTAACGCAATGTATGTTAGTGGAAAGCACATTTGGCTGGCC
TGGTATCGGTCGCTGGTTAATTGATGCCGTTACACAACAAGACTATAATAGTATTTCTGTGGGCGTGATCGTTATTGGCT
TATGTATTATCATCGTTGATGTATTATCAGAAAGTTTTGCCTTTATGCTCGATCCATTTAATAAGAAAGGCTGGTATGCA
AGATAA

Upstream 100 bases:

>100_bases
AACGGATGTTGGTGGTTAGCCCAAATGTGCAAGGCGTGAAAATGAGTCCATTTGGCAGTATTAATTTTGAAAACTTATCT
TTACGTAAAGGAGCAAAACC

Downstream 100 bases:

>100_bases
AGAACCTGATGAATTTCGCGAAAGTGCTGCAATAAAACATATCTGGCTATTATTTAGACAAGATCGTATCGCGCTATTTA
GCTTCTACCTTTTTATTGTT

Product: hypothetical protein

Products: ADP; phosphate; peptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 321; Mature: 321

Protein sequence:

>321_residues
MIVALLRQVFLVFLTLLILSLLSYMILIQDPLNEELMQPSLLQGYISHITHLLQGDFGITYNGGDSLNAIIQTVLPPTLE
LCFSAILLAVLFGIPLGLMGAMKSHTFLGKGIRTMSALGLSMPVFWIAPIALYFSAIHSWEISAIGQYNLLYAIKPITGF
PIIDVWFMDEFYRTKVIQNVLQHLVLPTLVLTILPTMEITRIVQQRAEDVLTKNYIKMAMTRGWSQNKILRKHVLRNTLP
LLIPQSTRLFTLVLTQCMLVESTFGWPGIGRWLIDAVTQQDYNSISVGVIVIGLCIIIVDVLSESFAFMLDPFNKKGWYA
R

Sequences:

>Translated_321_residues
MIVALLRQVFLVFLTLLILSLLSYMILIQDPLNEELMQPSLLQGYISHITHLLQGDFGITYNGGDSLNAIIQTVLPPTLE
LCFSAILLAVLFGIPLGLMGAMKSHTFLGKGIRTMSALGLSMPVFWIAPIALYFSAIHSWEISAIGQYNLLYAIKPITGF
PIIDVWFMDEFYRTKVIQNVLQHLVLPTLVLTILPTMEITRIVQQRAEDVLTKNYIKMAMTRGWSQNKILRKHVLRNTLP
LLIPQSTRLFTLVLTQCMLVESTFGWPGIGRWLIDAVTQQDYNSISVGVIVIGLCIIIVDVLSESFAFMLDPFNKKGWYA
R
>Mature_321_residues
MIVALLRQVFLVFLTLLILSLLSYMILIQDPLNEELMQPSLLQGYISHITHLLQGDFGITYNGGDSLNAIIQTVLPPTLE
LCFSAILLAVLFGIPLGLMGAMKSHTFLGKGIRTMSALGLSMPVFWIAPIALYFSAIHSWEISAIGQYNLLYAIKPITGF
PIIDVWFMDEFYRTKVIQNVLQHLVLPTLVLTILPTMEITRIVQQRAEDVLTKNYIKMAMTRGWSQNKILRKHVLRNTLP
LLIPQSTRLFTLVLTQCMLVESTFGWPGIGRWLIDAVTQQDYNSISVGVIVIGLCIIIVDVLSESFAFMLDPFNKKGWYA
R

Specific function: Involved in a peptide intake transport system that plays a role in the resistance to antimicrobial peptides [H]

COG id: COG4168

COG function: function code V; ABC-type antimicrobial peptide transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787550, Length=288, Percent_Identity=38.5416666666667, Blast_Score=229, Evalue=2e-61,
Organism=Escherichia coli, GI1789965, Length=291, Percent_Identity=29.553264604811, Blast_Score=129, Evalue=3e-31,
Organism=Escherichia coli, GI1789888, Length=287, Percent_Identity=27.1777003484321, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1787053, Length=277, Percent_Identity=24.5487364620939, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1787497, Length=332, Percent_Identity=22.5903614457831, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI1787761, Length=288, Percent_Identity=28.8194444444444, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1788504, Length=271, Percent_Identity=23.2472324723247, Blast_Score=66, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 36189; Mature: 36189

Theoretical pI: Translated: 8.44; Mature: 8.44

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIVALLRQVFLVFLTLLILSLLSYMILIQDPLNEELMQPSLLQGYISHITHLLQGDFGIT
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCHHHHHHHHHHHHHHHHCCCCEE
YNGGDSLNAIIQTVLPPTLELCFSAILLAVLFGIPLGLMGAMKSHTFLGKGIRTMSALGL
ECCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
SMPVFWIAPIALYFSAIHSWEISAIGQYNLLYAIKPITGFPIIDVWFMDEFYRTKVIQNV
CCHHHHHHHHHHHHHHHHCCCHHCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHH
LQHLVLPTLVLTILPTMEITRIVQQRAEDVLTKNYIKMAMTRGWSQNKILRKHVLRNTLP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCC
LLIPQSTRLFTLVLTQCMLVESTFGWPGIGRWLIDAVTQQDYNSISVGVIVIGLCIIIVD
CEECCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
VLSESFAFMLDPFNKKGWYAR
HHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MIVALLRQVFLVFLTLLILSLLSYMILIQDPLNEELMQPSLLQGYISHITHLLQGDFGIT
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCHHHHHHHHHHHHHHHHCCCCEE
YNGGDSLNAIIQTVLPPTLELCFSAILLAVLFGIPLGLMGAMKSHTFLGKGIRTMSALGL
ECCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
SMPVFWIAPIALYFSAIHSWEISAIGQYNLLYAIKPITGFPIIDVWFMDEFYRTKVIQNV
CCHHHHHHHHHHHHHHHHCCCHHCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHH
LQHLVLPTLVLTILPTMEITRIVQQRAEDVLTKNYIKMAMTRGWSQNKILRKHVLRNTLP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCC
LLIPQSTRLFTLVLTQCMLVESTFGWPGIGRWLIDAVTQQDYNSISVGVIVIGLCIIIVD
CEECCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
VLSESFAFMLDPFNKKGWYAR
HHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; peptides [Periplasm]; H2O [C]

Specific reaction: ATP + peptides [Periplasm] + H2O = ADP + phosphate + peptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]