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The map label for this gene is orn

Identifier: 15602765

GI number: 15602765

Start: 1059010

End: 1059564

Strand: Direct

Name: orn

Synonym: PM0900

Alternate gene names: 15602765

Gene position: 1059010-1059564 (Clockwise)

Preceding gene: 15602757

Following gene: 15602766

Centisome position: 46.91

GC content: 36.94

Gene sequence:

>555_bases
ATGCAGTTGGATAAACAAAATCTGATTTGGATTGATTTAGAAATGACCGGCTTAGACCCTGAAAGTGAACGTATTATTGA
GATTGCAACTATTGTGACCGATAAACATCTCAATATTTTGGCAGAAGGACCTGTACTTGCGATTCATCAATCAGATGAAT
GTTTAGCGAAAATGAACGACTGGTGTATGAAAACCCATACAGAGAACGGCTTAGTTGAACGTGTAAAAAACAGTCGTTTA
ACTGAACGAGCGGCAGAATTACAAACGCTAGATTTTCTAAAAAAATGGGTACCTAAAGGTGTTTCCCCCATTTGTGGAAA
TAGTGTTTCGCAAGATAAACGCTTTTTATTCAAATACATGCCTGAGTTAGCCGATTATTTTCACTATCGTCACCTAGATG
TCAGTACGTTAAAAGAATTAGCGAGTCGTTGGAAACCTGATGTGTTAAAAGGCTTTACTAAGAAAAACACTCACCTTGCG
TTAGATGACATACGTGAATCTATCGCTGAACTGGCTTACTACCGCGAACATTTTATTAATTTGAAAAATGAATAA

Upstream 100 bases:

>100_bases
TAATTTACGTTTACTCAATGACTTATCCTTAAAAGTGCGGTCGTTTTTTATCAGATTTTCCGCTAGAATAGCGACAAAAC
AATTTACATAGGATAGCACC

Downstream 100 bases:

>100_bases
TCTGAAAAAGTGACTTTCAATCAAACGAAAAGTCACTTTTCTTTTTAAGAGCAACATAAAAAGCCTAACTGATGCACTGT
TTCATTAGCCAAAGAATACC

Product: oligoribonuclease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 184; Mature: 184

Protein sequence:

>184_residues
MQLDKQNLIWIDLEMTGLDPESERIIEIATIVTDKHLNILAEGPVLAIHQSDECLAKMNDWCMKTHTENGLVERVKNSRL
TERAAELQTLDFLKKWVPKGVSPICGNSVSQDKRFLFKYMPELADYFHYRHLDVSTLKELASRWKPDVLKGFTKKNTHLA
LDDIRESIAELAYYREHFINLKNE

Sequences:

>Translated_184_residues
MQLDKQNLIWIDLEMTGLDPESERIIEIATIVTDKHLNILAEGPVLAIHQSDECLAKMNDWCMKTHTENGLVERVKNSRL
TERAAELQTLDFLKKWVPKGVSPICGNSVSQDKRFLFKYMPELADYFHYRHLDVSTLKELASRWKPDVLKGFTKKNTHLA
LDDIRESIAELAYYREHFINLKNE
>Mature_184_residues
MQLDKQNLIWIDLEMTGLDPESERIIEIATIVTDKHLNILAEGPVLAIHQSDECLAKMNDWCMKTHTENGLVERVKNSRL
TERAAELQTLDFLKKWVPKGVSPICGNSVSQDKRFLFKYMPELADYFHYRHLDVSTLKELASRWKPDVLKGFTKKNTHLA
LDDIRESIAELAYYREHFINLKNE

Specific function: 3'-to-5' exoribonuclease specific for small oligoribonucleotides

COG id: COG1949

COG function: function code A; Oligoribonuclease (3'->5' exoribonuclease)

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 exonuclease domain

Homologues:

Organism=Homo sapiens, GI224496106, Length=175, Percent_Identity=50.8571428571429, Blast_Score=184, Evalue=6e-47,
Organism=Escherichia coli, GI87082382, Length=181, Percent_Identity=73.4806629834254, Blast_Score=290, Evalue=5e-80,
Organism=Caenorhabditis elegans, GI17557752, Length=172, Percent_Identity=51.1627906976744, Blast_Score=166, Evalue=7e-42,
Organism=Saccharomyces cerevisiae, GI6323088, Length=191, Percent_Identity=37.17277486911, Blast_Score=127, Evalue=1e-30,
Organism=Drosophila melanogaster, GI21355135, Length=174, Percent_Identity=48.8505747126437, Blast_Score=179, Evalue=9e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ORN_PASMU (P57885)

Other databases:

- EMBL:   AE004439
- RefSeq:   NP_245837.1
- ProteinModelPortal:   P57885
- SMR:   P57885
- PRIDE:   P57885
- GeneID:   1244247
- GenomeReviews:   AE004439_GR
- KEGG:   pmu:PM0900
- NMPDR:   fig|272843.1.peg.900
- HOGENOM:   HBG448545
- OMA:   WNKGTHG
- ProtClustDB:   PRK05359
- BioCyc:   PMUL272843:PM0900-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00045
- InterPro:   IPR006055
- InterPro:   IPR013520
- InterPro:   IPR022894
- InterPro:   IPR012337
- SMART:   SM00479

Pfam domain/function: PF00929 Exonuc_X-T; SSF53098 RNaseH_fold

EC number: 3.1.-.- [C]

Molecular weight: Translated: 21428; Mature: 21428

Theoretical pI: Translated: 6.40; Mature: 6.40

Prosite motif: NA

Important sites: ACT_SITE 129-129

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLDKQNLIWIDLEMTGLDPESERIIEIATIVTDKHLNILAEGPVLAIHQSDECLAKMND
CCCCCCCEEEEEEEEECCCCCHHHHHHHHHHHHCCCCEEEECCCEEEEECCHHHHHHHHH
WCMKTHTENGLVERVKNSRLTERAAELQTLDFLKKWVPKGVSPICGNSVSQDKRFLFKYM
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHH
PELADYFHYRHLDVSTLKELASRWKPDVLKGFTKKNTHLALDDIRESIAELAYYREHFIN
HHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHC
LKNE
CCCC
>Mature Secondary Structure
MQLDKQNLIWIDLEMTGLDPESERIIEIATIVTDKHLNILAEGPVLAIHQSDECLAKMND
CCCCCCCEEEEEEEEECCCCCHHHHHHHHHHHHCCCCEEEECCCEEEEECCHHHHHHHHH
WCMKTHTENGLVERVKNSRLTERAAELQTLDFLKKWVPKGVSPICGNSVSQDKRFLFKYM
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHH
PELADYFHYRHLDVSTLKELASRWKPDVLKGFTKKNTHLALDDIRESIAELAYYREHFIN
HHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHC
LKNE
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11248100