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The map label for this gene is htrB [H]

Identifier: 15602750

GI number: 15602750

Start: 1040790

End: 1041731

Strand: Direct

Name: htrB [H]

Synonym: PM0885

Alternate gene names: 15602750

Gene position: 1040790-1041731 (Clockwise)

Preceding gene: 15602748

Following gene: 15602757

Centisome position: 46.1

GC content: 42.68

Gene sequence:

>942_bases
ATGGCGAACGATAAACTCCCAACATTTCAAAAAAGATTTCTAAAACCAAAACACTGGGGATTTTGGTTAGGCGTTGCCTT
ATGGCGTCTGATCGTATGTTTACCCTACCCGATTTTACACAAACTCGGGAACGGACTAGGCTGGTTACTCGCAAAATCAA
CAGTAGGTCAACGTCGCGCCAACATTGCACGTCGCAATTTACAGCTCTGTTTTCCCCACTATTCTGCGGATCAAATTGAA
ACCTTATTACATGCGAATTTAAAAGCCACCGGCATGGCGATTATTGAAACGGGTATGGCTTGGTTTTGGTCTGATGCAAG
AATAAAAAAATGGTCAAAAATCGAAGGTCTTGAATACTTAAAAGAATATAAACAAGATGGTGTGATTCTTGTTGGGGTAC
ATTTCCTAACCTTAGAATTGGGCGCCCGTATTGTTGGCTTGCATCAACCGGGCATAGGGGTTTACCGCCCGAATGACAAT
CCTTTAATGGACTGGTTACAAGTGCAAGGTCGCTTACGTTCTAATAAAGATCTGCTCGATCGTAAAGATTTACGTGGCAT
GATTCGTGCGTTACGCCAAGGTGAAATTATTTGGTATGCGCCTGATCATGATTATGGACGTAAAAATGCGGTCTTTGTGC
CCTTTTTTGCTGTCCCTGATGCAGCGACTACAACGGGGAGCTATTATTTATTAAAATCCTCACCAACAAGTAAGGTGATC
CCTTTTGCCCCATTACGCAATAGCGATGGGTCGGGTTATACCGTCAAAATCTCCCCCCCAGTGGATTTTTCCGATATTAC
AGATGAAACTCGTATTGCCACACGCATGAACCAAGTCGTAGAAACGGAAATTATGAAAGGAGTGGAACAATATATGTGGC
TACACCGCCGTTTTAAAACACGACCTGATGAAAATCAGCCAAGTTTATATGATGAGGAATAA

Upstream 100 bases:

>100_bases
AATATTCACGCCCTATTTATGCGATAATTCGTAATATGATTACAAGTTGAGTTATGTTTTCTCATTCTCAATTTATTACT
GAAGATACTCAAGCAATTTT

Downstream 100 bases:

>100_bases
GACCCCATCGTTCTTATGCGACAAAAAGTGCGGTGAGTTTTGGACAAAAATTAAAAGCAGCGTCGTAACGCTGCTTTTTT
AGCATGACAAGAAAATGCTT

Product: lipid A biosynthesis lauroyl acyltransferase

Products: NA

Alternate protein names: Heat shock protein B [H]

Number of amino acids: Translated: 313; Mature: 312

Protein sequence:

>313_residues
MANDKLPTFQKRFLKPKHWGFWLGVALWRLIVCLPYPILHKLGNGLGWLLAKSTVGQRRANIARRNLQLCFPHYSADQIE
TLLHANLKATGMAIIETGMAWFWSDARIKKWSKIEGLEYLKEYKQDGVILVGVHFLTLELGARIVGLHQPGIGVYRPNDN
PLMDWLQVQGRLRSNKDLLDRKDLRGMIRALRQGEIIWYAPDHDYGRKNAVFVPFFAVPDAATTTGSYYLLKSSPTSKVI
PFAPLRNSDGSGYTVKISPPVDFSDITDETRIATRMNQVVETEIMKGVEQYMWLHRRFKTRPDENQPSLYDEE

Sequences:

>Translated_313_residues
MANDKLPTFQKRFLKPKHWGFWLGVALWRLIVCLPYPILHKLGNGLGWLLAKSTVGQRRANIARRNLQLCFPHYSADQIE
TLLHANLKATGMAIIETGMAWFWSDARIKKWSKIEGLEYLKEYKQDGVILVGVHFLTLELGARIVGLHQPGIGVYRPNDN
PLMDWLQVQGRLRSNKDLLDRKDLRGMIRALRQGEIIWYAPDHDYGRKNAVFVPFFAVPDAATTTGSYYLLKSSPTSKVI
PFAPLRNSDGSGYTVKISPPVDFSDITDETRIATRMNQVVETEIMKGVEQYMWLHRRFKTRPDENQPSLYDEE
>Mature_312_residues
ANDKLPTFQKRFLKPKHWGFWLGVALWRLIVCLPYPILHKLGNGLGWLLAKSTVGQRRANIARRNLQLCFPHYSADQIET
LLHANLKATGMAIIETGMAWFWSDARIKKWSKIEGLEYLKEYKQDGVILVGVHFLTLELGARIVGLHQPGIGVYRPNDNP
LMDWLQVQGRLRSNKDLLDRKDLRGMIRALRQGEIIWYAPDHDYGRKNAVFVPFFAVPDAATTTGSYYLLKSSPTSKVIP
FAPLRNSDGSGYTVKISPPVDFSDITDETRIATRMNQVVETEIMKGVEQYMWLHRRFKTRPDENQPSLYDEE

Specific function: Acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(lauroyl)-lipid IVA [H]

COG id: COG1560

COG function: function code M; Lauroyl/myristoyl acyltransferase

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the htrB/msbB family [H]

Homologues:

Organism=Escherichia coli, GI1787292, Length=307, Percent_Identity=53.0944625407166, Blast_Score=339, Evalue=1e-94,
Organism=Escherichia coli, GI87082094, Length=304, Percent_Identity=47.6973684210526, Blast_Score=304, Evalue=6e-84,
Organism=Escherichia coli, GI1788161, Length=314, Percent_Identity=31.2101910828025, Blast_Score=122, Evalue=2e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004960
- InterPro:   IPR011920 [H]

Pfam domain/function: PF03279 Lip_A_acyltrans [H]

EC number: 2.3.1.-

Molecular weight: Translated: 35957; Mature: 35826

Theoretical pI: Translated: 9.92; Mature: 9.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANDKLPTFQKRFLKPKHWGFWLGVALWRLIVCLPYPILHKLGNGLGWLLAKSTVGQRRA
CCCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHCCHHHHHHHCCCHHHHHHHHHHHHHHH
NIARRNLQLCFPHYSADQIETLLHANLKATGMAIIETGMAWFWSDARIKKWSKIEGLEYL
HHHHCCCEEEECCCCHHHHHHHHHCCCCCCCHHHHHHCHHHEECCHHHHHHHHHHHHHHH
KEYKQDGVILVGVHFLTLELGARIVGLHQPGIGVYRPNDNPLMDWLQVQGRLRSNKDLLD
HHHHHCCEEEEEHHHHHHHHCCEEEEEECCCCEEECCCCCHHHHHHHHHHHHCCCCHHHH
RKDLRGMIRALRQGEIIWYAPDHDYGRKNAVFVPFFAVPDAATTTGSYYLLKSSPTSKVI
HHHHHHHHHHHHCCCEEEECCCCCCCCCCCEEEEEEECCCCCCCCCCEEEEECCCCCCCC
PFAPLRNSDGSGYTVKISPPVDFSDITDETRIATRMNQVVETEIMKGVEQYMWLHRRFKT
CCCCCCCCCCCCEEEEECCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
RPDENQPSLYDEE
CCCCCCCCCCCCC
>Mature Secondary Structure 
ANDKLPTFQKRFLKPKHWGFWLGVALWRLIVCLPYPILHKLGNGLGWLLAKSTVGQRRA
CCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHCCHHHHHHHCCCHHHHHHHHHHHHHHH
NIARRNLQLCFPHYSADQIETLLHANLKATGMAIIETGMAWFWSDARIKKWSKIEGLEYL
HHHHCCCEEEECCCCHHHHHHHHHCCCCCCCHHHHHHCHHHEECCHHHHHHHHHHHHHHH
KEYKQDGVILVGVHFLTLELGARIVGLHQPGIGVYRPNDNPLMDWLQVQGRLRSNKDLLD
HHHHHCCEEEEEHHHHHHHHCCEEEEEECCCCEEECCCCCHHHHHHHHHHHHCCCCHHHH
RKDLRGMIRALRQGEIIWYAPDHDYGRKNAVFVPFFAVPDAATTTGSYYLLKSSPTSKVI
HHHHHHHHHHHHCCCEEEECCCCCCCCCCCEEEEEEECCCCCCCCCCEEEEECCCCCCCC
PFAPLRNSDGSGYTVKISPPVDFSDITDETRIATRMNQVVETEIMKGVEQYMWLHRRFKT
CCCCCCCCCCCCEEEEECCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
RPDENQPSLYDEE
CCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Acyltransferases [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800; 7592970 [H]