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The map label for this gene is uup1 [H]

Identifier: 15602742

GI number: 15602742

Start: 1032003

End: 1033952

Strand: Reverse

Name: uup1 [H]

Synonym: PM0877

Alternate gene names: 15602742

Gene position: 1033952-1032003 (Counterclockwise)

Preceding gene: 15602743

Following gene: 15602740

Centisome position: 45.8

GC content: 40.31

Gene sequence:

>1950_bases
ATGGCACTCATTTCTCTCACCAATGGATATCTTTCCTTTAGTGATCATCCTTTATTAGATCATACCGACTTGCATATTGA
AGCCGGTGAGCGGGTTTGTTTAGTTGGACGTAATGGCGCAGGTAAATCTACGCTAATGAAAATCTTGGCGGGTGATGTCA
TTATGGATGACGGGCGTTTGCAGTTTGAAAAAGAGATTGTCGTTTCCCGTTTAGAGCAGGATCCACCGCGTCATGCGAGT
GGCAATGTGTTTGATTATGTCGCTGAAGGCATTGAACATTTAGCCGATTTATTAAAAGATTACCATCGCATTTCTTTGTT
ATTGGAACAGGACTGCAGTGATGCGGTCTTAAATCAATTGGCACAAGTGCAAGCGAAGTTAGATCATGCAGACGCTTGGC
GTTTTGAAAGTAAAATTAAAGACGTGTTGGCGACATTATCTTTACATCCGGATACCTTGTTATCTGAATTATCGGGTGGT
TGGTTACGTAAAGCCGCATTAGCCCGTGCGCTTGTTTGTGATCCTGATGTGTTGTTATTAGATGAACCGACCAACCATTT
AGATGTGGATGCGATTGAATGGTTAGAAAACTTTTTACTTGGTTTTTCGGGTAGCATTATTTTTATTTCTCATGACCGCG
CTTTTATTCGTAAAATGGCGACCCGTATTGTGGATTTAGACCGTGGCAAATTAGTGTCTTATCCGGGGGATTATGATTTA
TATCTTAGTACAAAAGAAGAAAATCTTCGCGTAGAGGCTCTACAAAATGAGTTATTTGATAAAAAATTGGCTCAAGAAGA
AGTTTGGATTCGACAGGGGATTAAAGCACGTAGAACGCGTAATGAGGGACGAGTTCGCGCCTTAAAAGCTTTGCGTGAAG
AACGTCGTCAACGTCGTGAAGTACTTGGTACGGCAAAACTCCAACTCGATAATTCTAGTCGTTCAGGCAAAATGGTGTTT
GAGATGGACAATGTGACTTATCAAGTGGCAGGCAAAACCTTATTAAAAGATTTCAGTACCACCATTTTACGAGGTGATAA
AATTGCCTTAGTGGGACCGAATGGTTGTGGTAAGACGACATTTATTAAATTGTTACTTGGTGAAATTCAACCAACTTCAG
GTACTGTACGTTGTGGGACCAAATTGGATATTGCTTATTTTGATCAATATCGTGCCGAACTCGATCCAGAAAAAACGGTG
ATGGATAATGTGGCTGACGGTAAACAAGATATTGAAGTGAATGGCATTAAACGTCATGTCTTAGGTTATTTACAAGATTT
TCTCTTTCCTCCGAAGCGGGCGATGACACCTGTGAAAGCGTTATCAGGTGGAGAGCGGAACCGTTTATTGTTAGCAAAAT
TATTACTCAAACCTAACAACTTATTGATTTTGGATGAACCGACCAATGATCTTGATGTTGAAACGCTGGAACTATTAGAA
GAAATTCTAACAGACTATCAGGGTACGCTATTAATCGTGAGTCACGATCGCCAATTTATTGATAATACCGCTGCGGAATG
TTTCATTTTTGAAGGCGAAGGGATTGTGAATGAATATGTCGGTGGATTCCATGAAGCGAAACAGCAACAAGCTAACTCTT
TTGCGCATAAAGCAGAACAAGCTGCGTTGAAACAGAAAAAGCCTGCTAGTTTAGAAAGTGCGGTCGATATCACGAAAAAT
TCTGTTTCCAACAAATCTCAAACCAAAGCAATAAAACTGACTTATAAAGAACAACGCGAGTTAGAACAATTGCCTCAACG
TTTGGAAACGTTAGAAGCGGAAATCAATTCCTTACAAGCTGAAATTGCGGGTAGTGAATTTTTTCAGCAATCGCATGAAT
ACACCTCTGCAAAATTGCAAGCATTAGCCGAAGCCGAGCAAGCGTTAGAAGAAGCGTTTATGCGTTGGGAAACCTTAGAG
GAAAAACAAAATTTAAGTAAATCAGGCTAA

Upstream 100 bases:

>100_bases
TGTTGGTCAACGCAGTCTAGACAATGTGGATAATGTGCTTATCCCTGTTGTGAAAACAGCATTTGTATTTTTATAAAAAG
TATTTTAACAAAGAGGCATT

Downstream 100 bases:

>100_bases
TTGATGTCGTAGGATTTGACGGTATTTACAAAAGAGAAAAGGGCGAAAAATTATTATTTTTCGCCCTTGTTTTCAAGTAA
ATATGTTACTTGACTTGTTG

Product: ABC transporter ATPase component

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 649; Mature: 648

Protein sequence:

>649_residues
MALISLTNGYLSFSDHPLLDHTDLHIEAGERVCLVGRNGAGKSTLMKILAGDVIMDDGRLQFEKEIVVSRLEQDPPRHAS
GNVFDYVAEGIEHLADLLKDYHRISLLLEQDCSDAVLNQLAQVQAKLDHADAWRFESKIKDVLATLSLHPDTLLSELSGG
WLRKAALARALVCDPDVLLLDEPTNHLDVDAIEWLENFLLGFSGSIIFISHDRAFIRKMATRIVDLDRGKLVSYPGDYDL
YLSTKEENLRVEALQNELFDKKLAQEEVWIRQGIKARRTRNEGRVRALKALREERRQRREVLGTAKLQLDNSSRSGKMVF
EMDNVTYQVAGKTLLKDFSTTILRGDKIALVGPNGCGKTTFIKLLLGEIQPTSGTVRCGTKLDIAYFDQYRAELDPEKTV
MDNVADGKQDIEVNGIKRHVLGYLQDFLFPPKRAMTPVKALSGGERNRLLLAKLLLKPNNLLILDEPTNDLDVETLELLE
EILTDYQGTLLIVSHDRQFIDNTAAECFIFEGEGIVNEYVGGFHEAKQQQANSFAHKAEQAALKQKKPASLESAVDITKN
SVSNKSQTKAIKLTYKEQRELEQLPQRLETLEAEINSLQAEIAGSEFFQQSHEYTSAKLQALAEAEQALEEAFMRWETLE
EKQNLSKSG

Sequences:

>Translated_649_residues
MALISLTNGYLSFSDHPLLDHTDLHIEAGERVCLVGRNGAGKSTLMKILAGDVIMDDGRLQFEKEIVVSRLEQDPPRHAS
GNVFDYVAEGIEHLADLLKDYHRISLLLEQDCSDAVLNQLAQVQAKLDHADAWRFESKIKDVLATLSLHPDTLLSELSGG
WLRKAALARALVCDPDVLLLDEPTNHLDVDAIEWLENFLLGFSGSIIFISHDRAFIRKMATRIVDLDRGKLVSYPGDYDL
YLSTKEENLRVEALQNELFDKKLAQEEVWIRQGIKARRTRNEGRVRALKALREERRQRREVLGTAKLQLDNSSRSGKMVF
EMDNVTYQVAGKTLLKDFSTTILRGDKIALVGPNGCGKTTFIKLLLGEIQPTSGTVRCGTKLDIAYFDQYRAELDPEKTV
MDNVADGKQDIEVNGIKRHVLGYLQDFLFPPKRAMTPVKALSGGERNRLLLAKLLLKPNNLLILDEPTNDLDVETLELLE
EILTDYQGTLLIVSHDRQFIDNTAAECFIFEGEGIVNEYVGGFHEAKQQQANSFAHKAEQAALKQKKPASLESAVDITKN
SVSNKSQTKAIKLTYKEQRELEQLPQRLETLEAEINSLQAEIAGSEFFQQSHEYTSAKLQALAEAEQALEEAFMRWETLE
EKQNLSKSG
>Mature_648_residues
ALISLTNGYLSFSDHPLLDHTDLHIEAGERVCLVGRNGAGKSTLMKILAGDVIMDDGRLQFEKEIVVSRLEQDPPRHASG
NVFDYVAEGIEHLADLLKDYHRISLLLEQDCSDAVLNQLAQVQAKLDHADAWRFESKIKDVLATLSLHPDTLLSELSGGW
LRKAALARALVCDPDVLLLDEPTNHLDVDAIEWLENFLLGFSGSIIFISHDRAFIRKMATRIVDLDRGKLVSYPGDYDLY
LSTKEENLRVEALQNELFDKKLAQEEVWIRQGIKARRTRNEGRVRALKALREERRQRREVLGTAKLQLDNSSRSGKMVFE
MDNVTYQVAGKTLLKDFSTTILRGDKIALVGPNGCGKTTFIKLLLGEIQPTSGTVRCGTKLDIAYFDQYRAELDPEKTVM
DNVADGKQDIEVNGIKRHVLGYLQDFLFPPKRAMTPVKALSGGERNRLLLAKLLLKPNNLLILDEPTNDLDVETLELLEE
ILTDYQGTLLIVSHDRQFIDNTAAECFIFEGEGIVNEYVGGFHEAKQQQANSFAHKAEQAALKQKKPASLESAVDITKNS
VSNKSQTKAIKLTYKEQRELEQLPQRLETLEAEINSLQAEIAGSEFFQQSHEYTSAKLQALAEAEQALEEAFMRWETLEE
KQNLSKSG

Specific function: Unknown

COG id: COG0488

COG function: function code R; ATPase components of ABC transporters with duplicated ATPase domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ABC transporter domains [H]

Homologues:

Organism=Homo sapiens, GI148612853, Length=542, Percent_Identity=33.3948339483395, Blast_Score=240, Evalue=3e-63,
Organism=Homo sapiens, GI27881506, Length=533, Percent_Identity=29.4559099437148, Blast_Score=200, Evalue=4e-51,
Organism=Homo sapiens, GI10947137, Length=533, Percent_Identity=29.4559099437148, Blast_Score=199, Evalue=6e-51,
Organism=Homo sapiens, GI69354671, Length=550, Percent_Identity=31.0909090909091, Blast_Score=194, Evalue=3e-49,
Organism=Homo sapiens, GI10947135, Length=550, Percent_Identity=31.0909090909091, Blast_Score=193, Evalue=4e-49,
Organism=Homo sapiens, GI156105685, Length=257, Percent_Identity=29.9610894941634, Blast_Score=76, Evalue=1e-13,
Organism=Homo sapiens, GI171184400, Length=250, Percent_Identity=28, Blast_Score=75, Evalue=2e-13,
Organism=Escherichia coli, GI1787182, Length=644, Percent_Identity=65.3726708074534, Blast_Score=825, Evalue=0.0,
Organism=Escherichia coli, GI2367384, Length=538, Percent_Identity=34.2007434944238, Blast_Score=307, Evalue=1e-84,
Organism=Escherichia coli, GI1787041, Length=521, Percent_Identity=32.4376199616123, Blast_Score=273, Evalue=3e-74,
Organism=Escherichia coli, GI1789751, Length=644, Percent_Identity=29.5031055900621, Blast_Score=267, Evalue=2e-72,
Organism=Escherichia coli, GI1788506, Length=538, Percent_Identity=23.7918215613383, Blast_Score=95, Evalue=1e-20,
Organism=Escherichia coli, GI145693107, Length=539, Percent_Identity=24.4897959183673, Blast_Score=90, Evalue=6e-19,
Organism=Escherichia coli, GI1788165, Length=192, Percent_Identity=31.25, Blast_Score=86, Evalue=9e-18,
Organism=Escherichia coli, GI87081791, Length=204, Percent_Identity=31.3725490196078, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1789672, Length=260, Percent_Identity=23.8461538461538, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI1788761, Length=234, Percent_Identity=27.7777777777778, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1790190, Length=218, Percent_Identity=27.0642201834862, Blast_Score=77, Evalue=5e-15,
Organism=Escherichia coli, GI1789891, Length=224, Percent_Identity=27.6785714285714, Blast_Score=74, Evalue=4e-14,
Organism=Escherichia coli, GI1787029, Length=241, Percent_Identity=29.045643153527, Blast_Score=73, Evalue=7e-14,
Organism=Escherichia coli, GI1786872, Length=203, Percent_Identity=31.0344827586207, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1787164, Length=184, Percent_Identity=33.695652173913, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI1788225, Length=248, Percent_Identity=26.6129032258064, Blast_Score=70, Evalue=6e-13,
Organism=Escherichia coli, GI87081709, Length=209, Percent_Identity=28.7081339712919, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI1786975, Length=185, Percent_Identity=28.6486486486486, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI1786563, Length=194, Percent_Identity=27.8350515463918, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI87081834, Length=211, Percent_Identity=31.7535545023697, Blast_Score=67, Evalue=4e-12,
Organism=Escherichia coli, GI1787712, Length=193, Percent_Identity=29.5336787564767, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1789962, Length=237, Percent_Identity=24.4725738396624, Blast_Score=64, Evalue=3e-11,
Organism=Escherichia coli, GI1786698, Length=197, Percent_Identity=27.4111675126904, Blast_Score=63, Evalue=5e-11,
Organism=Escherichia coli, GI1786398, Length=227, Percent_Identity=25.1101321585903, Blast_Score=63, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI17559834, Length=556, Percent_Identity=28.0575539568345, Blast_Score=218, Evalue=9e-57,
Organism=Caenorhabditis elegans, GI17555318, Length=556, Percent_Identity=27.6978417266187, Blast_Score=198, Evalue=8e-51,
Organism=Caenorhabditis elegans, GI17553372, Length=561, Percent_Identity=31.1942959001783, Blast_Score=191, Evalue=9e-49,
Organism=Saccharomyces cerevisiae, GI6320874, Length=526, Percent_Identity=29.0874524714829, Blast_Score=208, Evalue=2e-54,
Organism=Saccharomyces cerevisiae, GI6321121, Length=535, Percent_Identity=29.5327102803738, Blast_Score=206, Evalue=1e-53,
Organism=Saccharomyces cerevisiae, GI6323278, Length=383, Percent_Identity=27.4151436031332, Blast_Score=124, Evalue=4e-29,
Organism=Saccharomyces cerevisiae, GI6324314, Length=384, Percent_Identity=28.6458333333333, Blast_Score=124, Evalue=5e-29,
Organism=Saccharomyces cerevisiae, GI6325030, Length=388, Percent_Identity=26.8041237113402, Blast_Score=122, Evalue=3e-28,
Organism=Drosophila melanogaster, GI24641342, Length=553, Percent_Identity=29.4755877034358, Blast_Score=223, Evalue=3e-58,
Organism=Drosophila melanogaster, GI24666836, Length=539, Percent_Identity=31.5398886827458, Blast_Score=221, Evalue=2e-57,
Organism=Drosophila melanogaster, GI24642252, Length=558, Percent_Identity=30.2867383512545, Blast_Score=219, Evalue=4e-57,
Organism=Drosophila melanogaster, GI18859989, Length=558, Percent_Identity=30.2867383512545, Blast_Score=219, Evalue=4e-57,
Organism=Drosophila melanogaster, GI281363262, Length=230, Percent_Identity=26.9565217391304, Blast_Score=75, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24653245, Length=232, Percent_Identity=27.1551724137931, Blast_Score=74, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 72972; Mature: 72841

Theoretical pI: Translated: 5.12; Mature: 5.12

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALISLTNGYLSFSDHPLLDHTDLHIEAGERVCLVGRNGAGKSTLMKILAGDVIMDDGRL
CEEEEEECCEECCCCCCCCCCCCEEEECCCEEEEEECCCCCHHHHHHHHHCCEEECCCCH
QFEKEIVVSRLEQDPPRHASGNVFDYVAEGIEHLADLLKDYHRISLLLEQDCSDAVLNQL
HHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
AQVQAKLDHADAWRFESKIKDVLATLSLHPDTLLSELSGGWLRKAALARALVCDPDVLLL
HHHHHHHCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHCCCCCEEEE
DEPTNHLDVDAIEWLENFLLGFSGSIIFISHDRAFIRKMATRIVDLDRGKLVSYPGDYDL
ECCCCCCCCHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHCCCCCCEECCCCCEEE
YLSTKEENLRVEALQNELFDKKLAQEEVWIRQGIKARRTRNEGRVRALKALREERRQRRE
EEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCCHHHHHHHHHHHHHHHHHH
VLGTAKLQLDNSSRSGKMVFEMDNVTYQVAGKTLLKDFSTTILRGDKIALVGPNGCGKTT
HHHHHEEEECCCCCCCCEEEEECCEEEEHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHH
FIKLLLGEIQPTSGTVRCGTKLDIAYFDQYRAELDPEKTVMDNVADGKQDIEVNGIKRHV
HHHHHHHHCCCCCCCEEECCEEEHHHHHHHHHCCCCHHHHHHHHCCCCCCCEECHHHHHH
LGYLQDFLFPPKRAMTPVKALSGGERNRLLLAKLLLKPNNLLILDEPTNDLDVETLELLE
HHHHHHHCCCCHHHCCHHHHHCCCCCCHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHH
EILTDYQGTLLIVSHDRQFIDNTAAECFIFEGEGIVNEYVGGFHEAKQQQANSFAHKAEQ
HHHHCCCCEEEEEECCHHHHCCCCCEEEEECCCCHHHHHHCCHHHHHHHHHHHHHHHHHH
AALKQKKPASLESAVDITKNSVSNKSQTKAIKLTYKEQRELEQLPQRLETLEAEINSLQA
HHHHCCCCCCHHHHHHHHHHCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHH
EIAGSEFFQQSHEYTSAKLQALAEAEQALEEAFMRWETLEEKQNLSKSG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
ALISLTNGYLSFSDHPLLDHTDLHIEAGERVCLVGRNGAGKSTLMKILAGDVIMDDGRL
EEEEEECCEECCCCCCCCCCCCEEEECCCEEEEEECCCCCHHHHHHHHHCCEEECCCCH
QFEKEIVVSRLEQDPPRHASGNVFDYVAEGIEHLADLLKDYHRISLLLEQDCSDAVLNQL
HHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
AQVQAKLDHADAWRFESKIKDVLATLSLHPDTLLSELSGGWLRKAALARALVCDPDVLLL
HHHHHHHCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHCCCCCEEEE
DEPTNHLDVDAIEWLENFLLGFSGSIIFISHDRAFIRKMATRIVDLDRGKLVSYPGDYDL
ECCCCCCCCHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHCCCCCCEECCCCCEEE
YLSTKEENLRVEALQNELFDKKLAQEEVWIRQGIKARRTRNEGRVRALKALREERRQRRE
EEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCCHHHHHHHHHHHHHHHHHH
VLGTAKLQLDNSSRSGKMVFEMDNVTYQVAGKTLLKDFSTTILRGDKIALVGPNGCGKTT
HHHHHEEEECCCCCCCCEEEEECCEEEEHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHH
FIKLLLGEIQPTSGTVRCGTKLDIAYFDQYRAELDPEKTVMDNVADGKQDIEVNGIKRHV
HHHHHHHHCCCCCCCEEECCEEEHHHHHHHHHCCCCHHHHHHHHCCCCCCCEECHHHHHH
LGYLQDFLFPPKRAMTPVKALSGGERNRLLLAKLLLKPNNLLILDEPTNDLDVETLELLE
HHHHHHHCCCCHHHCCHHHHHCCCCCCHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHH
EILTDYQGTLLIVSHDRQFIDNTAAECFIFEGEGIVNEYVGGFHEAKQQQANSFAHKAEQ
HHHHCCCCEEEEEECCHHHHCCCCCEEEEECCCCHHHHHHCCHHHHHHHHHHHHHHHHHH
AALKQKKPASLESAVDITKNSVSNKSQTKAIKLTYKEQRELEQLPQRLETLEAEINSLQA
HHHHCCCCCCHHHHHHHHHHCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHH
EIAGSEFFQQSHEYTSAKLQALAEAEQALEEAFMRWETLEEKQNLSKSG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Endonuclease; Excision [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]