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The map label for this gene is nagA [H]

Identifier: 15602739

GI number: 15602739

Start: 1028200

End: 1029336

Strand: Reverse

Name: nagA [H]

Synonym: PM0874

Alternate gene names: 15602739

Gene position: 1029336-1028200 (Counterclockwise)

Preceding gene: 15602740

Following gene: 15602736

Centisome position: 45.6

GC content: 40.28

Gene sequence:

>1137_bases
ATGTACGCGTTTGTTAATGCCGTAATTTACACTGCAAAAGACGTACTTTATGGTAAAGCGCTTGTTGTCGATGGCGATAA
AATTAGTGCAATTCTACCCGTAGAAGACGTGCCAGAAAATCTTCAGAAAATTGATTTACAAGGGAATAATTTAACTGCAG
GTTTTATTGATCTTCAATTAAATGGCTGTGGTGGTGTGATGTTTAATGAAGATATTAGCGTGAAGACGTTAGAGATCATG
CAAGAAACTAATTTGAAATCCGGCACGACAAGTTATTTACCAACCTTTATTACGTCACCTGATGAAGGAATGAAAGACGC
GGTGAAGGTGATGCGTGAGTATTTAACTCAGTATAAAAATCAAGCATTAGGTTTACACTTTGAAGGACCATATTTGAGTG
TTGAGAAAAAAGGGGTACATCGCGAAGAATATATTCGTGCGATAAGCCCAGAAATGAAAACATTCTTGTGTGATAATGCA
GATGTGATTACTAAAATCACGTTGGCAGCCGAAAATCCAACGGCACAGTATATTCCAGACTTTGTTGAAAAAGGGATTAT
CGTCTCGCTTGGACACTCGAATGCGACTTACGATGTCGCACAACAGGCTATTGAGAAAGGGGCGAGTTTTGCAACCCATT
TACATAATGCAATGTCACCAATCAGCTCTGGACGAGCGATGGGAGTAGTGGGCGCCGTATTAGATTCTGATATCTATACA
GGTATTATTGTGGATGGTTTACACGTTGATTATGGCAATATACGACTCGACAAGAAAGTAAAAGGCGACAAATTGTGTAT
TGTGACAGATGCAACTGCTGCAGCCGGTGCAGACATTGACTCCTTTGTTTTCGTCGGTAAAACCGTCTATGTGCGTGATG
GTAAATGCTATGATAGCAATGGTACATTAGGTGGCGCTGCAATCACGATGATTGAGTCAGTGAAAAATGCGGTACAGGAA
GTTGGCATTCCATTGGATGAGACATTACGTATGTGTAATTACTATCCTGCTAAAGCAATTGGTGTGGATCATAAACTTGG
CTCAATTGAAGTGGGTAAAATCGCGAATTTAACAGCATTCACAAATGATTTTAACGTGTTGGGTACAGCCGTGAATGGTG
AATGGAAAGCGAAGTAA

Upstream 100 bases:

>100_bases
TGATGAACCTGCGACGCAAGAGCTTAAAGTGAAAACAGTTAAATATTTTACTGAATTAGAAGCCTCTGCTATTCGTAGCG
TGAAATAAAAGGAGATAAGC

Downstream 100 bases:

>100_bases
CACTTTCTCATTTTATTAAAAATAGCGTGTTAAATTAACACGCTATTTTTTTATCGCTAAATCAAAACCACGCCGGATAA
AAGTGGTTTTGTATTACATT

Product: N-acetylglucosamine-6-phosphate deacetylase

Products: NA

Alternate protein names: GlcNAc 6-P deacetylase [H]

Number of amino acids: Translated: 378; Mature: 378

Protein sequence:

>378_residues
MYAFVNAVIYTAKDVLYGKALVVDGDKISAILPVEDVPENLQKIDLQGNNLTAGFIDLQLNGCGGVMFNEDISVKTLEIM
QETNLKSGTTSYLPTFITSPDEGMKDAVKVMREYLTQYKNQALGLHFEGPYLSVEKKGVHREEYIRAISPEMKTFLCDNA
DVITKITLAAENPTAQYIPDFVEKGIIVSLGHSNATYDVAQQAIEKGASFATHLHNAMSPISSGRAMGVVGAVLDSDIYT
GIIVDGLHVDYGNIRLDKKVKGDKLCIVTDATAAAGADIDSFVFVGKTVYVRDGKCYDSNGTLGGAAITMIESVKNAVQE
VGIPLDETLRMCNYYPAKAIGVDHKLGSIEVGKIANLTAFTNDFNVLGTAVNGEWKAK

Sequences:

>Translated_378_residues
MYAFVNAVIYTAKDVLYGKALVVDGDKISAILPVEDVPENLQKIDLQGNNLTAGFIDLQLNGCGGVMFNEDISVKTLEIM
QETNLKSGTTSYLPTFITSPDEGMKDAVKVMREYLTQYKNQALGLHFEGPYLSVEKKGVHREEYIRAISPEMKTFLCDNA
DVITKITLAAENPTAQYIPDFVEKGIIVSLGHSNATYDVAQQAIEKGASFATHLHNAMSPISSGRAMGVVGAVLDSDIYT
GIIVDGLHVDYGNIRLDKKVKGDKLCIVTDATAAAGADIDSFVFVGKTVYVRDGKCYDSNGTLGGAAITMIESVKNAVQE
VGIPLDETLRMCNYYPAKAIGVDHKLGSIEVGKIANLTAFTNDFNVLGTAVNGEWKAK
>Mature_378_residues
MYAFVNAVIYTAKDVLYGKALVVDGDKISAILPVEDVPENLQKIDLQGNNLTAGFIDLQLNGCGGVMFNEDISVKTLEIM
QETNLKSGTTSYLPTFITSPDEGMKDAVKVMREYLTQYKNQALGLHFEGPYLSVEKKGVHREEYIRAISPEMKTFLCDNA
DVITKITLAAENPTAQYIPDFVEKGIIVSLGHSNATYDVAQQAIEKGASFATHLHNAMSPISSGRAMGVVGAVLDSDIYT
GIIVDGLHVDYGNIRLDKKVKGDKLCIVTDATAAAGADIDSFVFVGKTVYVRDGKCYDSNGTLGGAAITMIESVKNAVQE
VGIPLDETLRMCNYYPAKAIGVDHKLGSIEVGKIANLTAFTNDFNVLGTAVNGEWKAK

Specific function: N-acetylglucosamine utilization. [C]

COG id: COG1820

COG function: function code G; N-acetylglucosamine-6-phosphate deacetylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nagA family [H]

Homologues:

Organism=Homo sapiens, GI21361513, Length=389, Percent_Identity=29.5629820051414, Blast_Score=145, Evalue=7e-35,
Organism=Homo sapiens, GI224922791, Length=385, Percent_Identity=29.0909090909091, Blast_Score=142, Evalue=7e-34,
Organism=Escherichia coli, GI1786892, Length=377, Percent_Identity=54.9071618037135, Blast_Score=418, Evalue=1e-118,
Organism=Caenorhabditis elegans, GI17553768, Length=350, Percent_Identity=30.5714285714286, Blast_Score=143, Evalue=1e-34,
Organism=Drosophila melanogaster, GI19920392, Length=391, Percent_Identity=29.923273657289, Blast_Score=144, Evalue=1e-34,
Organism=Drosophila melanogaster, GI281361140, Length=405, Percent_Identity=29.1358024691358, Blast_Score=139, Evalue=4e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR003764
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.1.25 [H]

Molecular weight: Translated: 40800; Mature: 40800

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYAFVNAVIYTAKDVLYGKALVVDGDKISAILPVEDVPENLQKIDLQGNNLTAGFIDLQL
CCHHHHHHHHHHHHHHCCCEEEEECCCEEEEECHHHCCCCHHEEECCCCEEEEEEEEEEE
NGCGGVMFNEDISVKTLEIMQETNLKSGTTSYLPTFITSPDEGMKDAVKVMREYLTQYKN
CCCCCEEECCCCCEEHEEHHHHCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHCC
QALGLHFEGPYLSVEKKGVHREEYIRAISPEMKTFLCDNADVITKITLAAENPTAQYIPD
CEEEEEECCCEEEEECCCCCHHHHHHHHCCHHHHEECCCCCEEEEEEEEECCCCHHHCHH
FVEKGIIVSLGHSNATYDVAQQAIEKGASFATHLHNAMSPISSGRAMGVVGAVLDSDIYT
HHHCCEEEEECCCCCHHHHHHHHHHCCCHHHHHHHHHHCHHHCCCHHHHHHHHHCCCCEE
GIIVDGLHVDYGNIRLDKKVKGDKLCIVTDATAAAGADIDSFVFVGKTVYVRDGKCYDSN
EEEEEEEEECCCCEEECCCCCCCEEEEEECCCCCCCCCCCCEEEECEEEEEECCEEECCC
GTLGGAAITMIESVKNAVQEVGIPLDETLRMCNYYPAKAIGVDHKLGSIEVGKIANLTAF
CCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCHHCCCCCCCCCEEECCEEEEEEE
TNDFNVLGTAVNGEWKAK
CCCCEEEEEEECCCCCCC
>Mature Secondary Structure
MYAFVNAVIYTAKDVLYGKALVVDGDKISAILPVEDVPENLQKIDLQGNNLTAGFIDLQL
CCHHHHHHHHHHHHHHCCCEEEEECCCEEEEECHHHCCCCHHEEECCCCEEEEEEEEEEE
NGCGGVMFNEDISVKTLEIMQETNLKSGTTSYLPTFITSPDEGMKDAVKVMREYLTQYKN
CCCCCEEECCCCCEEHEEHHHHCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHCC
QALGLHFEGPYLSVEKKGVHREEYIRAISPEMKTFLCDNADVITKITLAAENPTAQYIPD
CEEEEEECCCEEEEECCCCCHHHHHHHHCCHHHHEECCCCCEEEEEEEEECCCCHHHCHH
FVEKGIIVSLGHSNATYDVAQQAIEKGASFATHLHNAMSPISSGRAMGVVGAVLDSDIYT
HHHCCEEEEECCCCCHHHHHHHHHHCCCHHHHHHHHHHCHHHCCCHHHHHHHHHCCCCEE
GIIVDGLHVDYGNIRLDKKVKGDKLCIVTDATAAAGADIDSFVFVGKTVYVRDGKCYDSN
EEEEEEEEECCCCEEECCCCCCCEEEEEECCCCCCCCCCCCEEEECEEEEEECCEEECCC
GTLGGAAITMIESVKNAVQEVGIPLDETLRMCNYYPAKAIGVDHKLGSIEVGKIANLTAF
CCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCHHCCCCCCCCCEEECCEEEEEEE
TNDFNVLGTAVNGEWKAK
CCCCEEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]