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The map label for this gene is hns [H]

Identifier: 15602737

GI number: 15602737

Start: 1026768

End: 1027172

Strand: Direct

Name: hns [H]

Synonym: PM0872

Alternate gene names: 15602737

Gene position: 1026768-1027172 (Clockwise)

Preceding gene: 15602732

Following gene: 15602738

Centisome position: 45.48

GC content: 38.27

Gene sequence:

>405_bases
ATGAGTGATTTATTAAAGATGTTAACCAATGTTCGAAGTTTACGTGTGCTGGCTCGTGAAACCTCATTAGAACAACTTGA
AATTGCTTTAGAAAAGTTCTCTCTCGTCGTTGAAGAAAAACGTGAAGCTGAAGCCAAAGCAGAACGTGAAATAGCAGAAC
GTCAGGCAAGAATTGCGAAGTTGAAAGAATCATTAATCCAAGAAGGAATTACAGCCCAGGAATTAGCAATTTTGTTAGGC
CAAGAATCTCAATCTCAACGTAAAAAGAGAGAACCTCGCCCAGCAAAATACAAATATATCGATGAAAATGGTGAAGAAAG
AACTTGGACTGGTCAAGGTAGAACACCAAAAGTCATTCAAAAAGCCTTGGATGCGGGTAAATCCCTGAGTTCATTCGAAA
TTTAA

Upstream 100 bases:

>100_bases
CATTTACCAATAATAATATTTACTATATCATTACTTACGTTTGATTATGTTTAATTATATTTTATGTAATCCCTGTGTGA
CATTATATAGAGGAACAAGT

Downstream 100 bases:

>100_bases
TTTATTTTACTTTGTCGTAAAGCCCATTTCTTGATGGGTTTTCTTTTTTATTTTTTCGACTAAAACAACACACTTATGAT
TGAAAATAAAATATTATTAA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 134; Mature: 133

Protein sequence:

>134_residues
MSDLLKMLTNVRSLRVLARETSLEQLEIALEKFSLVVEEKREAEAKAEREIAERQARIAKLKESLIQEGITAQELAILLG
QESQSQRKKREPRPAKYKYIDENGEERTWTGQGRTPKVIQKALDAGKSLSSFEI

Sequences:

>Translated_134_residues
MSDLLKMLTNVRSLRVLARETSLEQLEIALEKFSLVVEEKREAEAKAEREIAERQARIAKLKESLIQEGITAQELAILLG
QESQSQRKKREPRPAKYKYIDENGEERTWTGQGRTPKVIQKALDAGKSLSSFEI
>Mature_133_residues
SDLLKMLTNVRSLRVLARETSLEQLEIALEKFSLVVEEKREAEAKAEREIAERQARIAKLKESLIQEGITAQELAILLGQ
ESQSQRKKREPRPAKYKYIDENGEERTWTGQGRTPKVIQKALDAGKSLSSFEI

Specific function: Binds tightly to ds-DNA, increases its thermal stability and inhibits transcription [H]

COG id: COG2916

COG function: function code R; DNA-binding protein H-NS

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the histone-like protein H-NS family [H]

Homologues:

Organism=Escherichia coli, GI1789023, Length=137, Percent_Identity=51.8248175182482, Blast_Score=116, Evalue=5e-28,
Organism=Escherichia coli, GI1787489, Length=135, Percent_Identity=51.8518518518518, Blast_Score=113, Evalue=5e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001801 [H]

Pfam domain/function: PF00816 Histone_HNS [H]

EC number: NA

Molecular weight: Translated: 15297; Mature: 15166

Theoretical pI: Translated: 9.53; Mature: 9.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
0.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDLLKMLTNVRSLRVLARETSLEQLEIALEKFSLVVEEKREAEAKAEREIAERQARIAK
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LKESLIQEGITAQELAILLGQESQSQRKKREPRPAKYKYIDENGEERTWTGQGRTPKVIQ
HHHHHHHCCCCHHHHHHHHCCCHHHHHHHCCCCCCCEEECCCCCCCCEECCCCCCHHHHH
KALDAGKSLSSFEI
HHHHCCCCCCCCCC
>Mature Secondary Structure 
SDLLKMLTNVRSLRVLARETSLEQLEIALEKFSLVVEEKREAEAKAEREIAERQARIAK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LKESLIQEGITAQELAILLGQESQSQRKKREPRPAKYKYIDENGEERTWTGQGRTPKVIQ
HHHHHHHCCCCHHHHHHHHCCCHHHHHHHCCCCCCCEEECCCCCCCCEECCCCCCHHHHH
KALDAGKSLSSFEI
HHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]