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The map label for this gene is pcnB [H]

Identifier: 15602729

GI number: 15602729

Start: 1017059

End: 1018564

Strand: Direct

Name: pcnB [H]

Synonym: PM0864

Alternate gene names: 15602729

Gene position: 1017059-1018564 (Clockwise)

Preceding gene: 15602728

Following gene: 15602730

Centisome position: 45.05

GC content: 41.17

Gene sequence:

>1506_bases
ATGAGGTCTATTATTTTAAAATACATCAAAAATCTGTTTAATAAAAAAACAAAATCCTATTTAGTCGAAAGAGAAAAAAC
AGATTCTACTCCATTATTATCCAAAAACGCACATTCTGAGCCCATAACAACAAGCGAGATTCGGAATGTGTCAAATAGCA
AACAAGCCAAACTTTCGCACCATTACAATAAATCGATTTTTAAAGCATCGCAGTACGGTATTACTCCCCGCATGATTAAT
CGCAATGCCTTAGGGATTGTGGAAAAACTGCATCGCCATGGTTTTGAAGCCTATATTGTCGGTGGCTGTTTAAGAGATTT
ATTGCTTGGGAAACACCCAAAAGATTTCGATGTGGCGACGAATGCATTACCAGAACAAATTCAAACGATCTTTCAACGTC
AATGTCGTTTAGTCGGTCGTCGTTTCCGATTGGCCCATATCATGTTTGGTCGAGATGTCATTGAAGTTGCGACCTTTCGT
GCAAGTCATAATGAAAATAATCATGAAAGCCTCGCTAAACAAAGCAAAGAAGGCATGCTGTTACGGGATAATGTGTATGG
CACATTAGAACAAGATGCGGAACGCCGCGATTTTACCGTTAATGCACTGTACTATAACCCACAAGATAATACCCTGCGTG
ATTATTTTCATGGTATTGAGGATCTCAAAGCTGGCAAATTACGCTTAATTGGCGATCCGGTAAAACGTTATCAAGAAGAT
CCCGTGCGGATGCTACGCTCAGTACGTTTCATGGCAAAATTGGATATGTTCCTTGAAAAACCAAGCGAACAGCCAATTCG
TGAGCTAGCGCCGTTACTTAAAAATATTCCACCAGCAAGGCTATTTGATGAATGTTTAAAATTACTCCAAGCTGGATACG
GCGTAAAAACCTATAAACTGTTACGTCAATATGGACTATTTGAGCAACTCTTCCCTTCACTGATGCCTTATTTCACAGAG
AAAGGTGACAGTCTTGCAGAACGGATGATTCTCAAAGCACTGACTTCCACAGATGAACGTGTAGCTGACAAATTACGCAT
CAATCCCGCGTTCTTATTTGCCGCTTTCTTCTGGTATCCATTACGTGAAAAAGTGGAGATGTTGAAAAATGAAGGTGGAT
TAAATAATCATGATGCCTATGCCTTGGCTAGCTCTGAAATTTTAGATTTATTCTGTGCCGCCCTTGCCGCGCCTCGTCGT
CACACTGCTGTGATCCGAGATATCTGGTTTTTGCAATTGCAATTACTCAAACGTTCAGGACAGCAACCTATTCGCACGAT
GGAACACCCTAAGTTCCGTGCGGCGTTTGATCTATTAGCAATGCGCTCAGAGGTTGAAGGTGGAGAAACCATTGAGCTTG
CAACCTGGTGGCATGAATATCAATTTAGTAATTCAGAACAACGTGATCACTTGGTCAAAGAGCAACAACGTTTACACCCT
AAGCCGAAGAAAAAATATTATCGTGCGAGAAAGCGTCGTAAGCCTAAAGCCATCTCGTCCTCATAG

Upstream 100 bases:

>100_bases
AATGGTTGGCTAACCTATTTTCCCCGTTATTATAATTAAAACATCTCGAAAGTGCGGTTTGTTTCACCGCACTTTTTTAC
AAATATGCTAAACACACTTG

Downstream 100 bases:

>100_bases
GGTAACTTAATATGAAGTCTGTCTATATTGCATTAGGAAGCAATTTACAAACACCAATTGCGCAGTTAGAGGCGGCTCTG
GCGGCATTAGCTAACTTACC

Product: hypothetical protein

Products: NA

Alternate protein names: PAP [H]

Number of amino acids: Translated: 501; Mature: 501

Protein sequence:

>501_residues
MRSIILKYIKNLFNKKTKSYLVEREKTDSTPLLSKNAHSEPITTSEIRNVSNSKQAKLSHHYNKSIFKASQYGITPRMIN
RNALGIVEKLHRHGFEAYIVGGCLRDLLLGKHPKDFDVATNALPEQIQTIFQRQCRLVGRRFRLAHIMFGRDVIEVATFR
ASHNENNHESLAKQSKEGMLLRDNVYGTLEQDAERRDFTVNALYYNPQDNTLRDYFHGIEDLKAGKLRLIGDPVKRYQED
PVRMLRSVRFMAKLDMFLEKPSEQPIRELAPLLKNIPPARLFDECLKLLQAGYGVKTYKLLRQYGLFEQLFPSLMPYFTE
KGDSLAERMILKALTSTDERVADKLRINPAFLFAAFFWYPLREKVEMLKNEGGLNNHDAYALASSEILDLFCAALAAPRR
HTAVIRDIWFLQLQLLKRSGQQPIRTMEHPKFRAAFDLLAMRSEVEGGETIELATWWHEYQFSNSEQRDHLVKEQQRLHP
KPKKKYYRARKRRKPKAISSS

Sequences:

>Translated_501_residues
MRSIILKYIKNLFNKKTKSYLVEREKTDSTPLLSKNAHSEPITTSEIRNVSNSKQAKLSHHYNKSIFKASQYGITPRMIN
RNALGIVEKLHRHGFEAYIVGGCLRDLLLGKHPKDFDVATNALPEQIQTIFQRQCRLVGRRFRLAHIMFGRDVIEVATFR
ASHNENNHESLAKQSKEGMLLRDNVYGTLEQDAERRDFTVNALYYNPQDNTLRDYFHGIEDLKAGKLRLIGDPVKRYQED
PVRMLRSVRFMAKLDMFLEKPSEQPIRELAPLLKNIPPARLFDECLKLLQAGYGVKTYKLLRQYGLFEQLFPSLMPYFTE
KGDSLAERMILKALTSTDERVADKLRINPAFLFAAFFWYPLREKVEMLKNEGGLNNHDAYALASSEILDLFCAALAAPRR
HTAVIRDIWFLQLQLLKRSGQQPIRTMEHPKFRAAFDLLAMRSEVEGGETIELATWWHEYQFSNSEQRDHLVKEQQRLHP
KPKKKYYRARKRRKPKAISSS
>Mature_501_residues
MRSIILKYIKNLFNKKTKSYLVEREKTDSTPLLSKNAHSEPITTSEIRNVSNSKQAKLSHHYNKSIFKASQYGITPRMIN
RNALGIVEKLHRHGFEAYIVGGCLRDLLLGKHPKDFDVATNALPEQIQTIFQRQCRLVGRRFRLAHIMFGRDVIEVATFR
ASHNENNHESLAKQSKEGMLLRDNVYGTLEQDAERRDFTVNALYYNPQDNTLRDYFHGIEDLKAGKLRLIGDPVKRYQED
PVRMLRSVRFMAKLDMFLEKPSEQPIRELAPLLKNIPPARLFDECLKLLQAGYGVKTYKLLRQYGLFEQLFPSLMPYFTE
KGDSLAERMILKALTSTDERVADKLRINPAFLFAAFFWYPLREKVEMLKNEGGLNNHDAYALASSEILDLFCAALAAPRR
HTAVIRDIWFLQLQLLKRSGQQPIRTMEHPKFRAAFDLLAMRSEVEGGETIELATWWHEYQFSNSEQRDHLVKEQQRLHP
KPKKKYYRARKRRKPKAISSS

Specific function: Polymerase that creates the 3' poly(A) tail found in some mRNA's [H]

COG id: COG0617

COG function: function code J; tRNA nucleotidyltransferase/poly(A) polymerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family [H]

Homologues:

Organism=Homo sapiens, GI155030240, Length=218, Percent_Identity=31.1926605504587, Blast_Score=96, Evalue=1e-19,
Organism=Escherichia coli, GI87081691, Length=412, Percent_Identity=54.126213592233, Blast_Score=468, Evalue=1e-133,
Organism=Caenorhabditis elegans, GI71995920, Length=303, Percent_Identity=25.7425742574257, Blast_Score=85, Evalue=8e-17,
Organism=Saccharomyces cerevisiae, GI6321016, Length=172, Percent_Identity=30.8139534883721, Blast_Score=67, Evalue=7e-12,
Organism=Drosophila melanogaster, GI281360112, Length=243, Percent_Identity=26.7489711934156, Blast_Score=96, Evalue=7e-20,
Organism=Drosophila melanogaster, GI21357337, Length=243, Percent_Identity=26.7489711934156, Blast_Score=96, Evalue=7e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002646
- InterPro:   IPR010206 [H]

Pfam domain/function: PF01743 PolyA_pol [H]

EC number: =2.7.7.19 [H]

Molecular weight: Translated: 58328; Mature: 58328

Theoretical pI: Translated: 10.25; Mature: 10.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSIILKYIKNLFNKKTKSYLVEREKTDSTPLLSKNAHSEPITTSEIRNVSNSKQAKLSH
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHCCCCHHHHHHH
HYNKSIFKASQYGITPRMINRNALGIVEKLHRHGFEAYIVGGCLRDLLLGKHPKDFDVAT
HHHHHHHHHHHCCCCHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCHHHHH
NALPEQIQTIFQRQCRLVGRRFRLAHIMFGRDVIEVATFRASHNENNHESLAKQSKEGML
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCE
LRDNVYGTLEQDAERRDFTVNALYYNPQDNTLRDYFHGIEDLKAGKLRLIGDPVKRYQED
EECCCCCCHHHHHCCCCEEEEEEEECCCCCHHHHHHCCHHHHCCCCEEEECCHHHHHHHH
PVRMLRSVRFMAKLDMFLEKPSEQPIRELAPLLKNIPPARLFDECLKLLQAGYGVKTYKL
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHH
LRQYGLFEQLFPSLMPYFTEKGDSLAERMILKALTSTDERVADKLRINPAFLFAAFFWYP
HHHHCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHH
LREKVEMLKNEGGLNNHDAYALASSEILDLFCAALAAPRRHTAVIRDIWFLQLQLLKRSG
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCC
QQPIRTMEHPKFRAAFDLLAMRSEVEGGETIELATWWHEYQFSNSEQRDHLVKEQQRLHP
CCCHHHHCCCHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHCCCCHHHHHHHHHHHHCCC
KPKKKYYRARKRRKPKAISSS
CHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MRSIILKYIKNLFNKKTKSYLVEREKTDSTPLLSKNAHSEPITTSEIRNVSNSKQAKLSH
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHCCCCHHHHHHH
HYNKSIFKASQYGITPRMINRNALGIVEKLHRHGFEAYIVGGCLRDLLLGKHPKDFDVAT
HHHHHHHHHHHCCCCHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCHHHHH
NALPEQIQTIFQRQCRLVGRRFRLAHIMFGRDVIEVATFRASHNENNHESLAKQSKEGML
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCE
LRDNVYGTLEQDAERRDFTVNALYYNPQDNTLRDYFHGIEDLKAGKLRLIGDPVKRYQED
EECCCCCCHHHHHCCCCEEEEEEEECCCCCHHHHHHCCHHHHCCCCEEEECCHHHHHHHH
PVRMLRSVRFMAKLDMFLEKPSEQPIRELAPLLKNIPPARLFDECLKLLQAGYGVKTYKL
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHH
LRQYGLFEQLFPSLMPYFTEKGDSLAERMILKALTSTDERVADKLRINPAFLFAAFFWYP
HHHHCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHH
LREKVEMLKNEGGLNNHDAYALASSEILDLFCAALAAPRRHTAVIRDIWFLQLQLLKRSG
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCC
QQPIRTMEHPKFRAAFDLLAMRSEVEGGETIELATWWHEYQFSNSEQRDHLVKEQQRLHP
CCCHHHHCCCHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHCCCCHHHHHHHHHHHHCCC
KPKKKYYRARKRRKPKAISSS
CHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]