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The map label for this gene is kdsB

Identifier: 15602723

GI number: 15602723

Start: 1010061

End: 1010837

Strand: Reverse

Name: kdsB

Synonym: PM0858

Alternate gene names: 15602723

Gene position: 1010837-1010061 (Counterclockwise)

Preceding gene: 15602724

Following gene: 15602722

Centisome position: 44.78

GC content: 42.6

Gene sequence:

>777_bases
ATGACAAATTTTACGGTCATTATCCCTGCACGTTATGCGTCAACACGTTTACCTGGGAAACCTTTAGCGGAGATTGCGGG
AAAACCGATGATTGCACATGTCTTTGAAAAGGCGATGCAGTCAGGTGCAAAACGCGTCATTGTTGCGACAGATCATGAAC
AAGTTGCGACAGTTGCACGAGGATTTGGCGCAGAAGTTTGCATGACATCTGAAACGCATCAGTCAGGAACTGAGCGATTA
GCTGAAGTGGTTGAGAAGTTAGGTATTGCGGAAGATGAAATCATTGTCAATATTCAAGGAGACGAACCCTTGATCCCACC
GGCAATTGTACGTCAAGTTGCTGAGAATTTAGCAAAATACCAAGTAAAAATGGCAAGTTTGGCGGTCAACATAACGGACC
CCGAAGAATTGTTCAATCCTAATGCGGTCAAAGTATTGACCGATCATGCCGGCTATGTGTTGTATTTTTCCCGTGCACCG
ATTCCATGGCATCGTGATCAATTTGCCTCTTTACCAAAAGAAAAAAGCACAAGAGGACAATTGGTCTTGTCCGATCACTA
TTTACGTCATATAGGTATTTATGCCTATCGTGCAGGTTTTATTAAACAGTATATTCAATGGCAACCGAGTGTATTAGAGC
AGATTGAAAGCTTAGAGCAATTACGAGTGTTATGGTATGGTGAAAAAATCCATGTAGAATTAGCGCGAGAAGTGCCGCCG
GTTGGCGTGGATACCGCTGAAGATTTAGAAAAAGTGCGGTCAATTTTAGAAAAATAA

Upstream 100 bases:

>100_bases
TGTCATTTTGATAAAGTTGCTTATGACATCAATCAAGGTATCCCGGTATTGTTAGCGGAACAAGCCATGCCTTTATCCGC
AAGACAAGAGGAGCCGTAAT

Downstream 100 bases:

>100_bases
AGGGCAGGCGTTTAGCGACGCCTGATGCTGTTTATGTTTGATGCCAAATCCTTTTTAGCCAATGTTTCCCACGATGCGGG
TGTTTATCGTATGTATGACG

Product: 3-deoxy-manno-octulosonate cytidylyltransferase

Products: NA

Alternate protein names: CMP-2-keto-3-deoxyoctulosonic acid synthase; CKS; CMP-KDO synthase

Number of amino acids: Translated: 258; Mature: 257

Protein sequence:

>258_residues
MTNFTVIIPARYASTRLPGKPLAEIAGKPMIAHVFEKAMQSGAKRVIVATDHEQVATVARGFGAEVCMTSETHQSGTERL
AEVVEKLGIAEDEIIVNIQGDEPLIPPAIVRQVAENLAKYQVKMASLAVNITDPEELFNPNAVKVLTDHAGYVLYFSRAP
IPWHRDQFASLPKEKSTRGQLVLSDHYLRHIGIYAYRAGFIKQYIQWQPSVLEQIESLEQLRVLWYGEKIHVELAREVPP
VGVDTAEDLEKVRSILEK

Sequences:

>Translated_258_residues
MTNFTVIIPARYASTRLPGKPLAEIAGKPMIAHVFEKAMQSGAKRVIVATDHEQVATVARGFGAEVCMTSETHQSGTERL
AEVVEKLGIAEDEIIVNIQGDEPLIPPAIVRQVAENLAKYQVKMASLAVNITDPEELFNPNAVKVLTDHAGYVLYFSRAP
IPWHRDQFASLPKEKSTRGQLVLSDHYLRHIGIYAYRAGFIKQYIQWQPSVLEQIESLEQLRVLWYGEKIHVELAREVPP
VGVDTAEDLEKVRSILEK
>Mature_257_residues
TNFTVIIPARYASTRLPGKPLAEIAGKPMIAHVFEKAMQSGAKRVIVATDHEQVATVARGFGAEVCMTSETHQSGTERLA
EVVEKLGIAEDEIIVNIQGDEPLIPPAIVRQVAENLAKYQVKMASLAVNITDPEELFNPNAVKVLTDHAGYVLYFSRAPI
PWHRDQFASLPKEKSTRGQLVLSDHYLRHIGIYAYRAGFIKQYIQWQPSVLEQIESLEQLRVLWYGEKIHVELAREVPPV
GVDTAEDLEKVRSILEK

Specific function: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria

COG id: COG1212

COG function: function code M; CMP-2-keto-3-deoxyoctulosonic acid synthetase

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the kdsB family

Homologues:

Organism=Escherichia coli, GI1787147, Length=252, Percent_Identity=65.8730158730159, Blast_Score=344, Evalue=3e-96,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): KDSB_PASMU (P57883)

Other databases:

- EMBL:   AE004439
- RefSeq:   NP_245795.1
- ProteinModelPortal:   P57883
- SMR:   P57883
- GeneID:   1244205
- GenomeReviews:   AE004439_GR
- KEGG:   pmu:PM0858
- NMPDR:   fig|272843.1.peg.858
- HOGENOM:   HBG637773
- OMA:   FSRAPLP
- ProtClustDB:   PRK05450
- BioCyc:   PMUL272843:PM0858-MONOMER
- BRENDA:   2.7.7.38
- GO:   GO:0005737
- HAMAP:   MF_00057
- InterPro:   IPR003329
- InterPro:   IPR004528
- TIGRFAMs:   TIGR00466

Pfam domain/function: PF02348 CTP_transf_3

EC number: =2.7.7.38

Molecular weight: Translated: 28878; Mature: 28746

Theoretical pI: Translated: 6.32; Mature: 6.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNFTVIIPARYASTRLPGKPLAEIAGKPMIAHVFEKAMQSGAKRVIVATDHEQVATVAR
CCCEEEEEECHHHCCCCCCCCHHHHCCCCHHHHHHHHHHHCCCCEEEEEECHHHHHHHHH
GFGAEVCMTSETHQSGTERLAEVVEKLGIAEDEIIVNIQGDEPLIPPAIVRQVAENLAKY
CCCCCEEECCCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHH
QVKMASLAVNITDPEELFNPNAVKVLTDHAGYVLYFSRAPIPWHRDQFASLPKEKSTRGQ
HHHHHHEEEECCCHHHHCCCCEEEEEECCCCEEEEEECCCCCCCCHHHHCCCCCCCCCCC
LVLSDHYLRHIGIYAYRAGFIKQYIQWQPSVLEQIESLEQLRVLWYGEKIHVELAREVPP
EEEHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCEEEEEEHHCCCC
VGVDTAEDLEKVRSILEK
CCCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
TNFTVIIPARYASTRLPGKPLAEIAGKPMIAHVFEKAMQSGAKRVIVATDHEQVATVAR
CCEEEEEECHHHCCCCCCCCHHHHCCCCHHHHHHHHHHHCCCCEEEEEECHHHHHHHHH
GFGAEVCMTSETHQSGTERLAEVVEKLGIAEDEIIVNIQGDEPLIPPAIVRQVAENLAKY
CCCCCEEECCCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHH
QVKMASLAVNITDPEELFNPNAVKVLTDHAGYVLYFSRAPIPWHRDQFASLPKEKSTRGQ
HHHHHHEEEECCCHHHHCCCCEEEEEECCCCEEEEEECCCCCCCCHHHHCCCCCCCCCCC
LVLSDHYLRHIGIYAYRAGFIKQYIQWQPSVLEQIESLEQLRVLWYGEKIHVELAREVPP
EEEHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCEEEEEEHHCCCC
VGVDTAEDLEKVRSILEK
CCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11248100