Click here to switch to the map view.

The map label for this gene is pgsA [H]

Identifier: 15602721

GI number: 15602721

Start: 1007548

End: 1008105

Strand: Reverse

Name: pgsA [H]

Synonym: PM0856

Alternate gene names: 15602721

Gene position: 1008105-1007548 (Counterclockwise)

Preceding gene: 15602722

Following gene: 15602720

Centisome position: 44.66

GC content: 38.71

Gene sequence:

>558_bases
ATGAAACCAAATATTCCTATATTCCTTACGCTTTTCCGTGTCATTTTAATTCCTTTTTTTGTCATTGCATTTTATTTGCC
TTTCTCGTGGTCGCCTTTTTTAACTGTATTGATTTTTTTTATTGCTGGCGTCACAGATTGGTTTGATGGTTATCTTGCAC
GAAAATGGAAACAAACGACACGTTTTGGCGCATTTTTAGATCCTGTTGCGGATAAAGTGATGGTAACAGTCGCCCTCGCT
TTGGTTGTTGAATATCACCATTCTTTTTGGATTACTTTGCCAGCAGTGATCATGATTTCTAGAGAAATCATCATTTCCGC
ATTAAGAGAATGGATGGCTGAAATTGGCGACAGGAATAAAGTGGCGGTATCTTGGCTCGGAAAAGTGAAAACCACAGCAC
AAATGTTAGCGTTAGGTGGATTGTTGTGGCGCTATAATGTGGTGATGGAAATTGCTGCGATTGTTTTACTGTATGTTGCG
GCGATTTTAACCGTTTGGTCGATGTTACAATATTTAAAAGCGGCTAAAGGCAGCTTACTTTCGGATATTACACTTTAA

Upstream 100 bases:

>100_bases
ATTAATACATGAATCTTATTAGGATATGAAAATTCCATTTTCAAATAAAACAGATATGTTTTAGAATAATTAGACTATAA
AAACGGACCTGACTCTTTCT

Downstream 100 bases:

>100_bases
ATACGTTTAAAGGCACTTTCTCCAGTGCCTTTTCTTTTGCCTCTATTTTAGGTTGGAGAATAAGCGTTTTTTTATATTGT
GATTTGTTTTTAAGCGATTA

Product: hypothetical protein

Products: NA

Alternate protein names: Phosphatidylglycerophosphate synthase; PGP synthase [H]

Number of amino acids: Translated: 185; Mature: 185

Protein sequence:

>185_residues
MKPNIPIFLTLFRVILIPFFVIAFYLPFSWSPFLTVLIFFIAGVTDWFDGYLARKWKQTTRFGAFLDPVADKVMVTVALA
LVVEYHHSFWITLPAVIMISREIIISALREWMAEIGDRNKVAVSWLGKVKTTAQMLALGGLLWRYNVVMEIAAIVLLYVA
AILTVWSMLQYLKAAKGSLLSDITL

Sequences:

>Translated_185_residues
MKPNIPIFLTLFRVILIPFFVIAFYLPFSWSPFLTVLIFFIAGVTDWFDGYLARKWKQTTRFGAFLDPVADKVMVTVALA
LVVEYHHSFWITLPAVIMISREIIISALREWMAEIGDRNKVAVSWLGKVKTTAQMLALGGLLWRYNVVMEIAAIVLLYVA
AILTVWSMLQYLKAAKGSLLSDITL
>Mature_185_residues
MKPNIPIFLTLFRVILIPFFVIAFYLPFSWSPFLTVLIFFIAGVTDWFDGYLARKWKQTTRFGAFLDPVADKVMVTVALA
LVVEYHHSFWITLPAVIMISREIIISALREWMAEIGDRNKVAVSWLGKVKTTAQMLALGGLLWRYNVVMEIAAIVLLYVA
AILTVWSMLQYLKAAKGSLLSDITL

Specific function: This protein catalyzes the committed step to the synthesis of the acidic phospholipids [H]

COG id: COG0558

COG function: function code I; Phosphatidylglycerophosphate synthase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDP-alcohol phosphatidyltransferase class-I family [H]

Homologues:

Organism=Escherichia coli, GI1788220, Length=182, Percent_Identity=69.2307692307692, Blast_Score=264, Evalue=2e-72,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000462
- InterPro:   IPR004570 [H]

Pfam domain/function: PF01066 CDP-OH_P_transf [H]

EC number: =2.7.8.5 [H]

Molecular weight: Translated: 21035; Mature: 21035

Theoretical pI: Translated: 10.02; Mature: 10.02

Prosite motif: PS00379 CDP_ALCOHOL_P_TRANSF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPNIPIFLTLFRVILIPFFVIAFYLPFSWSPFLTVLIFFIAGVTDWFDGYLARKWKQTT
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RFGAFLDPVADKVMVTVALALVVEYHHSFWITLPAVIMISREIIISALREWMAEIGDRNK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
VAVSWLGKVKTTAQMLALGGLLWRYNVVMEIAAIVLLYVAAILTVWSMLQYLKAAKGSLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHH
SDITL
HHCCC
>Mature Secondary Structure
MKPNIPIFLTLFRVILIPFFVIAFYLPFSWSPFLTVLIFFIAGVTDWFDGYLARKWKQTT
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RFGAFLDPVADKVMVTVALALVVEYHHSFWITLPAVIMISREIIISALREWMAEIGDRNK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
VAVSWLGKVKTTAQMLALGGLLWRYNVVMEIAAIVLLYVAAILTVWSMLQYLKAAKGSLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHH
SDITL
HHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]