Click here to switch to the map view.

The map label for this gene is ubiG

Identifier: 15602705

GI number: 15602705

Start: 990370

End: 991098

Strand: Reverse

Name: ubiG

Synonym: PM0840

Alternate gene names: 15602705

Gene position: 991098-990370 (Counterclockwise)

Preceding gene: 15602708

Following gene: 15602701

Centisome position: 43.9

GC content: 41.56

Gene sequence:

>729_bases
ATGCAAAATATTGATCAACAAGAACTTGATAAGTTTGAGAAAATGGCAAAAAGCTGGTGGGATCCGCAAGGGGATTTCAA
ACCGATCCATCAACTTAATCCGTTACGTTTAAGCTATATTGCACAGCAAGCCAACGGGCTAACGGGGAAAAAAGTGCTGG
ATGTGGGCTGTGGCGGTGGCATTTTGTCAGAAAGCATGGCAAAGCAAGGCGCAATTGTGACGGGGATTGATATGTCTTCT
GCCCCATTACAAGTGGCAAGAAAACATGCTTTAGAAAGCGGGCTACACATTGATTATCAACAAATTACGATTGAGGAATT
TTTGCAAAATCAGACCGCACTTTTTGCTGAAAGAGGGGAGGACGAAAAGTTTGATGTGATTACTTGCATGGAAATGCTTG
AGCATGTGCCTGACCCGAGTTCGATTATTGCCTGTTGTAAGCAATTATTAAAACCAAACGGGGTGATTTTTTTCTCCACC
ATTAATCGAACCCTTAAAGCCTGGGCATTGGTGATTATTGGTGCGGAATATGTGTTGAAAATGTTGCCGAAAGGGACACA
CGATTACGACAAATTTATTAAGCCAGCGGAATTGCTTCATTGGTGTGATGAAGCACAATTAACCTGTTTAGATATGGTAG
GCTATCATTACAATCCATTGACGGGTAAATTCTGGCTCAATAAAGATGTCAGCGCAAATTATATGGCGAGTTTTCGGATT
CAGTCTTAA

Upstream 100 bases:

>100_bases
AGCATAAAATCTAGTGTTCCCCTAATTTTATAGTGAAATTTTGCCTGATTTGGGGAATAATAACGTATTGTTTCTATTCA
AAATCATAAGAAGAAATTTC

Downstream 100 bases:

>100_bases
GGTGTTTTCTTGCATTATCTCAGACCCGATTCGTCACTCAAAAAGCGAAGTATTATAAAATACTTCGCTTTTTGCTGAGT
ACTTATCTGTAGGCTAACTT

Product: 3-demethylubiquinone-9 3-methyltransferase

Products: NA

Alternate protein names: 3,4-dihydroxy-5-hexaprenylbenzoate methyltransferase; DHHB methyltransferase

Number of amino acids: Translated: 242; Mature: 242

Protein sequence:

>242_residues
MQNIDQQELDKFEKMAKSWWDPQGDFKPIHQLNPLRLSYIAQQANGLTGKKVLDVGCGGGILSESMAKQGAIVTGIDMSS
APLQVARKHALESGLHIDYQQITIEEFLQNQTALFAERGEDEKFDVITCMEMLEHVPDPSSIIACCKQLLKPNGVIFFST
INRTLKAWALVIIGAEYVLKMLPKGTHDYDKFIKPAELLHWCDEAQLTCLDMVGYHYNPLTGKFWLNKDVSANYMASFRI
QS

Sequences:

>Translated_242_residues
MQNIDQQELDKFEKMAKSWWDPQGDFKPIHQLNPLRLSYIAQQANGLTGKKVLDVGCGGGILSESMAKQGAIVTGIDMSS
APLQVARKHALESGLHIDYQQITIEEFLQNQTALFAERGEDEKFDVITCMEMLEHVPDPSSIIACCKQLLKPNGVIFFST
INRTLKAWALVIIGAEYVLKMLPKGTHDYDKFIKPAELLHWCDEAQLTCLDMVGYHYNPLTGKFWLNKDVSANYMASFRI
QS
>Mature_242_residues
MQNIDQQELDKFEKMAKSWWDPQGDFKPIHQLNPLRLSYIAQQANGLTGKKVLDVGCGGGILSESMAKQGAIVTGIDMSS
APLQVARKHALESGLHIDYQQITIEEFLQNQTALFAERGEDEKFDVITCMEMLEHVPDPSSIIACCKQLLKPNGVIFFST
INRTLKAWALVIIGAEYVLKMLPKGTHDYDKFIKPAELLHWCDEAQLTCLDMVGYHYNPLTGKFWLNKDVSANYMASFRI
QS

Specific function: Ubiquinone biosynthesis. [C]

COG id: COG2227

COG function: function code H; 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. UbiG/COQ3 family

Homologues:

Organism=Homo sapiens, GI118600965, Length=247, Percent_Identity=35.6275303643725, Blast_Score=161, Evalue=4e-40,
Organism=Escherichia coli, GI1788564, Length=234, Percent_Identity=56.8376068376068, Blast_Score=298, Evalue=3e-82,
Organism=Caenorhabditis elegans, GI115533050, Length=244, Percent_Identity=30.7377049180328, Blast_Score=127, Evalue=7e-30,
Organism=Saccharomyces cerevisiae, GI6324476, Length=287, Percent_Identity=32.404181184669, Blast_Score=138, Evalue=1e-33,
Organism=Drosophila melanogaster, GI281365311, Length=237, Percent_Identity=31.6455696202532, Blast_Score=129, Evalue=3e-30,
Organism=Drosophila melanogaster, GI24585589, Length=217, Percent_Identity=32.258064516129, Blast_Score=127, Evalue=8e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UBIG_PASMU (Q9CMI6)

Other databases:

- EMBL:   AE004439
- RefSeq:   NP_245777.1
- ProteinModelPortal:   Q9CMI6
- GeneID:   1244187
- GenomeReviews:   AE004439_GR
- KEGG:   pmu:PM0840
- NMPDR:   fig|272843.1.peg.840
- HOGENOM:   HBG738842
- OMA:   DHAEIAK
- ProtClustDB:   PRK05134
- BioCyc:   PMUL272843:PM0840-MONOMER
- BRENDA:   2.1.1.64
- HAMAP:   MF_00472
- InterPro:   IPR013216
- InterPro:   IPR010233
- TIGRFAMs:   TIGR01983

Pfam domain/function: PF08241 Methyltransf_11

EC number: =2.1.1.64

Molecular weight: Translated: 27285; Mature: 27285

Theoretical pI: Translated: 5.88; Mature: 5.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQNIDQQELDKFEKMAKSWWDPQGDFKPIHQLNPLRLSYIAQQANGLTGKKVLDVGCGGG
CCCCCHHHHHHHHHHHHHHCCCCCCCCHHHCCCCHHHHHHHHHHCCCCCCCEEEECCCCC
ILSESMAKQGAIVTGIDMSSAPLQVARKHALESGLHIDYQQITIEEFLQNQTALFAERGE
HHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHCHHHHHHHHCCC
DEKFDVITCMEMLEHVPDPSSIIACCKQLLKPNGVIFFSTINRTLKAWALVIIGAEYVLK
CCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHH
MLPKGTHDYDKFIKPAELLHWCDEAQLTCLDMVGYHYNPLTGKFWLNKDVSANYMASFRI
HCCCCCCCHHHHCCHHHHHHHHCCCHHHHHHHHCCCCCCCCCEEEECCCCCCCEEEEEEE
QS
CC
>Mature Secondary Structure
MQNIDQQELDKFEKMAKSWWDPQGDFKPIHQLNPLRLSYIAQQANGLTGKKVLDVGCGGG
CCCCCHHHHHHHHHHHHHHCCCCCCCCHHHCCCCHHHHHHHHHHCCCCCCCEEEECCCCC
ILSESMAKQGAIVTGIDMSSAPLQVARKHALESGLHIDYQQITIEEFLQNQTALFAERGE
HHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHCHHHHHHHHCCC
DEKFDVITCMEMLEHVPDPSSIIACCKQLLKPNGVIFFSTINRTLKAWALVIIGAEYVLK
CCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHH
MLPKGTHDYDKFIKPAELLHWCDEAQLTCLDMVGYHYNPLTGKFWLNKDVSANYMASFRI
HCCCCCCCHHHHCCHHHHHHHHCCCHHHHHHHHCCCCCCCCCEEEECCCCCCCEEEEEEE
QS
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11248100