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The map label for this gene is prc [H]

Identifier: 15602134

GI number: 15602134

Start: 304324

End: 306375

Strand: Direct

Name: prc [H]

Synonym: PM0269

Alternate gene names: 15602134

Gene position: 304324-306375 (Clockwise)

Preceding gene: 15602133

Following gene: 15602135

Centisome position: 13.48

GC content: 37.91

Gene sequence:

>2052_bases
ATGAAATTGAGTAAAACAAAAAGTTATTTAGCAACGTTTTTGTTAAGTACTTTCTTAATGAGCTTTAATCTTGTCGAGGC
AGTACAGCCAAAAATCAAATTAAGCGATATTGTTACGCCACAACCTACGGAAGAAAATCAATTAGCGACAAAACGGGCGA
CAACTCGTTTAACGCAAAGTCATTATCGTAAGTTCCAGTTAAATGACGCGTTTTCTGAGAAAATTTTTGAGCGTTATCTT
AAGTCATTAGATTTTAGCCGAAATACTTTTCTACAATCTGATATTGATGAAATGCGCGCAAAATATGCCGATAAGTTTGA
TGATGCATTAAATGAAGGGGATTTAAGTATTGCCTTTGCAATGTACGATTTAATGATGAAAAGACGCTATGATCGTTATA
AATACGCGCTTTCTTTATTAGATAAAGAGCCTGATTTATCGGGTCAGGATCAAATTGAAATCGATCGTGAGAAATCCCCG
TGGCCAAAAGACAACGCAGAATTAGATAAGTTGTGGGAACAACGAGTTAAAAACGACATTATCAATCAGAAATTAAAAGA
TAAAAAATGGTCTGATATTAAGAAACGTTTAATTAAACGTTATGATTTGGCGATTCGTCGTTTAACCCAGACTAAAGCAG
ATGACATTCTTCAGGTGTATTTAAATGCCTTTGCACGAGAAGTGGATCCGCACACAAGCTATTTGGCACCGAGAACAGCG
AAAAGTTTTAACGAAAGTATGAACCTGTCGTTAGAAGGGATTGGCGCGACATTACAACAAACGGAAGATGATGGGACAAC
GATTAAATCATTAGTGCCAGGGGCACCTGCAGAACGGAGCAAAAAATTGAAAGCAGGTGACCGCATTATTGGTGTAGGGC
AAGCCAGCGGTGAAATCGAAGATGTTGTAGGTTGGCGTTTAGAAGATATTGTTGACAAAATTAAAGGTAAGAAAGGCACA
AAAGTGCGTTTAGAAATTGAGCCTGCGAAAGGGGGCAAATCTAAGATTATTACCTTAGTGCGCGATAAAGTTCGTATTGA
AGATCAAGCCGCAAAACTCACAATCAGCAAAGTAGAGGGGCAAATTGTCGCCTCAATTAAGATTCCAAGTTTTTACATTG
GATTGACACAAGATGTGAGAAAATTATTGGCTGAAATGAAAACGAAAAAAGCAAAAGCCTTAATTATTGACTTACGCGAT
AATGGCGGTGGCGCATTAACCGAAGCGGTTGGGTTAAGCGGTTTATTTATTAGCGATGGACCGATTGTTCAAGTGCGCGA
TGCTTTTCAACGTATTCGCGTTCATGAAGATCCAGACAGTGAACAAGTTTATTCTGGACCTTTATTAGTGATGATTAACC
GTTTTAGTGCTTCAGCTTCAGAGATTTTTGCTGCCGCAATGCAGGATTATAATCGTGGAATTATTATTGGGCAGAATACT
TTTGGTAAGGGAACAGTACAGCAAAGTCGTTCGTTAAACTTTGCGTTCGATGCCAATCAAGAACCTTTAGGTCTGATTCA
ATATACTATTCAGAAGTTTTATCGTATTGATGGTGGAAGTACTCAATTAAAAGGCGTGGCAACTGACATTGATTTCCCCG
CTGCGATTGATGCGAAAGAATATGGTGAGGAAAGAGAAGATAATGCGTTGCCTTGGGATAAAATTCCTGCCGCAAATTAC
TTTGAAGTCGCACAAGCGCGTGATGCAGTAGCGTTCTTAACACCAAAGCATATTGAACGCATAGCTAAAGATCCCGAATT
TGTCGCATTAAATGAAGAGCTTAAAATTCGTGATGAAAGAAACGCATTAAAATATTTGTCGTTGAATTATCAAAAGCGCA
AAATTGAAAATGATAAAGATGATGCAAGACGTTTAAAAGACTTAAATGCACGCTTTAAACGTGAGGGTAAAAAACCATTA
AAAGATCTGGATGATTTAGCAAAAGATTATGAGGCGCCAGATTTTTATTTAAAAGAAGCAGAGAGAATGGCAGCTGATCT
TGTTCAGTTTGAAACCGAAAAAATGGGTATGAATCAGAAAAGCACAAACTAG

Upstream 100 bases:

>100_bases
TTGCATAAGATGAAATAAGTACAAAATGCCATCAAATAAGGTGGCATTTATTGATCAAAGTGATTAATCATAAATTGTAT
TTTCTTTTTAGGAAGGTGAA

Downstream 100 bases:

>100_bases
TTTTATTTTGACCGCACTTTCATCATGAGAGTGGCGGTCATTTTCTCATTTATGTTAAGGAACTATGTGATGTTAAAGAT
AAAATCATTTAAATTTGCAC

Product: carboxy-terminal protease

Products: NA

Alternate protein names: C-terminal-processing peptidase; Protease Re [H]

Number of amino acids: Translated: 683; Mature: 683

Protein sequence:

>683_residues
MKLSKTKSYLATFLLSTFLMSFNLVEAVQPKIKLSDIVTPQPTEENQLATKRATTRLTQSHYRKFQLNDAFSEKIFERYL
KSLDFSRNTFLQSDIDEMRAKYADKFDDALNEGDLSIAFAMYDLMMKRRYDRYKYALSLLDKEPDLSGQDQIEIDREKSP
WPKDNAELDKLWEQRVKNDIINQKLKDKKWSDIKKRLIKRYDLAIRRLTQTKADDILQVYLNAFAREVDPHTSYLAPRTA
KSFNESMNLSLEGIGATLQQTEDDGTTIKSLVPGAPAERSKKLKAGDRIIGVGQASGEIEDVVGWRLEDIVDKIKGKKGT
KVRLEIEPAKGGKSKIITLVRDKVRIEDQAAKLTISKVEGQIVASIKIPSFYIGLTQDVRKLLAEMKTKKAKALIIDLRD
NGGGALTEAVGLSGLFISDGPIVQVRDAFQRIRVHEDPDSEQVYSGPLLVMINRFSASASEIFAAAMQDYNRGIIIGQNT
FGKGTVQQSRSLNFAFDANQEPLGLIQYTIQKFYRIDGGSTQLKGVATDIDFPAAIDAKEYGEEREDNALPWDKIPAANY
FEVAQARDAVAFLTPKHIERIAKDPEFVALNEELKIRDERNALKYLSLNYQKRKIENDKDDARRLKDLNARFKREGKKPL
KDLDDLAKDYEAPDFYLKEAERMAADLVQFETEKMGMNQKSTN

Sequences:

>Translated_683_residues
MKLSKTKSYLATFLLSTFLMSFNLVEAVQPKIKLSDIVTPQPTEENQLATKRATTRLTQSHYRKFQLNDAFSEKIFERYL
KSLDFSRNTFLQSDIDEMRAKYADKFDDALNEGDLSIAFAMYDLMMKRRYDRYKYALSLLDKEPDLSGQDQIEIDREKSP
WPKDNAELDKLWEQRVKNDIINQKLKDKKWSDIKKRLIKRYDLAIRRLTQTKADDILQVYLNAFAREVDPHTSYLAPRTA
KSFNESMNLSLEGIGATLQQTEDDGTTIKSLVPGAPAERSKKLKAGDRIIGVGQASGEIEDVVGWRLEDIVDKIKGKKGT
KVRLEIEPAKGGKSKIITLVRDKVRIEDQAAKLTISKVEGQIVASIKIPSFYIGLTQDVRKLLAEMKTKKAKALIIDLRD
NGGGALTEAVGLSGLFISDGPIVQVRDAFQRIRVHEDPDSEQVYSGPLLVMINRFSASASEIFAAAMQDYNRGIIIGQNT
FGKGTVQQSRSLNFAFDANQEPLGLIQYTIQKFYRIDGGSTQLKGVATDIDFPAAIDAKEYGEEREDNALPWDKIPAANY
FEVAQARDAVAFLTPKHIERIAKDPEFVALNEELKIRDERNALKYLSLNYQKRKIENDKDDARRLKDLNARFKREGKKPL
KDLDDLAKDYEAPDFYLKEAERMAADLVQFETEKMGMNQKSTN
>Mature_683_residues
MKLSKTKSYLATFLLSTFLMSFNLVEAVQPKIKLSDIVTPQPTEENQLATKRATTRLTQSHYRKFQLNDAFSEKIFERYL
KSLDFSRNTFLQSDIDEMRAKYADKFDDALNEGDLSIAFAMYDLMMKRRYDRYKYALSLLDKEPDLSGQDQIEIDREKSP
WPKDNAELDKLWEQRVKNDIINQKLKDKKWSDIKKRLIKRYDLAIRRLTQTKADDILQVYLNAFAREVDPHTSYLAPRTA
KSFNESMNLSLEGIGATLQQTEDDGTTIKSLVPGAPAERSKKLKAGDRIIGVGQASGEIEDVVGWRLEDIVDKIKGKKGT
KVRLEIEPAKGGKSKIITLVRDKVRIEDQAAKLTISKVEGQIVASIKIPSFYIGLTQDVRKLLAEMKTKKAKALIIDLRD
NGGGALTEAVGLSGLFISDGPIVQVRDAFQRIRVHEDPDSEQVYSGPLLVMINRFSASASEIFAAAMQDYNRGIIIGQNT
FGKGTVQQSRSLNFAFDANQEPLGLIQYTIQKFYRIDGGSTQLKGVATDIDFPAAIDAKEYGEEREDNALPWDKIPAANY
FEVAQARDAVAFLTPKHIERIAKDPEFVALNEELKIRDERNALKYLSLNYQKRKIENDKDDARRLKDLNARFKREGKKPL
KDLDDLAKDYEAPDFYLKEAERMAADLVQFETEKMGMNQKSTN

Specific function: Involved in the cleavage of a C-terminal peptide of 11 residues from the precursor form of penicillin-binding protein 3 (PBP3). May be involved in protection of the bacterium from thermal and osmotic stresses [H]

COG id: COG0793

COG function: function code M; Periplasmic protease

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Periplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PDZ (DHR) domain [H]

Homologues:

Organism=Escherichia coli, GI1788134, Length=646, Percent_Identity=51.8575851393189, Blast_Score=646, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR005151
- InterPro:   IPR004447
- InterPro:   IPR020992 [H]

Pfam domain/function: PF11818 DUF3340; PF00595 PDZ; PF03572 Peptidase_S41 [H]

EC number: =3.4.21.102 [H]

Molecular weight: Translated: 77642; Mature: 77642

Theoretical pI: Translated: 9.20; Mature: 9.20

Prosite motif: PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLSKTKSYLATFLLSTFLMSFNLVEAVQPKIKLSDIVTPQPTEENQLATKRATTRLTQS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEHHHCCCCCCCCCHHHHHHHHHHHHHHH
HYRKFQLNDAFSEKIFERYLKSLDFSRNTFLQSDIDEMRAKYADKFDDALNEGDLSIAFA
HHHEEECCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
MYDLMMKRRYDRYKYALSLLDKEPDLSGQDQIEIDREKSPWPKDNAELDKLWEQRVKNDI
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEECCCCCCCCCCCCHHHHHHHHHHHHHH
INQKLKDKKWSDIKKRLIKRYDLAIRRLTQTKADDILQVYLNAFAREVDPHTSYLAPRTA
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCHHH
KSFNESMNLSLEGIGATLQQTEDDGTTIKSLVPGAPAERSKKLKAGDRIIGVGQASGEIE
HHHCCCCCEEEECCCCHHHCCCCCCCCHHHHCCCCCHHHHHHCCCCCCEEEECCCCCCHH
DVVGWRLEDIVDKIKGKKGTKVRLEIEPAKGGKSKIITLVRDKVRIEDQAAKLTISKVEG
HHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCHHEEHHHHHHHHCCHHHHHEEEEECCC
QIVASIKIPSFYIGLTQDVRKLLAEMKTKKAKALIIDLRDNGGGALTEAVGLSGLFISDG
EEEEEEECCEEEECCHHHHHHHHHHHHHCCCEEEEEEEECCCCCHHHHHHCCCEEEECCC
PIVQVRDAFQRIRVHEDPDSEQVYSGPLLVMINRFSASASEIFAAAMQDYNRGIIIGQNT
CEEHHHHHHHHCCCCCCCCCCHHHCCCEEEEEECCCCCHHHHHHHHHHHCCCCEEEECCC
FGKGTVQQSRSLNFAFDANQEPLGLIQYTIQKFYRIDGGSTQLKGVATDIDFPAAIDAKE
CCCCCHHHCCCCEEEECCCCCCHHHHHHHHHHHHCCCCCCCEECEEEECCCCCCCCCHHH
YGEEREDNALPWDKIPAANYFEVAQARDAVAFLTPKHIERIAKDPEFVALNEELKIRDER
CCCCCCCCCCCCCCCCCCCHHHHHHHCCHHEECCHHHHHHHHCCCCEEEECCCEEECCHH
NALKYLSLNYQKRKIENDKDDARRLKDLNARFKREGKKPLKDLDDLAKDYEAPDFYLKEA
HHHHHHHCCCHHHHCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHH
ERMAADLVQFETEKMGMNQKSTN
HHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MKLSKTKSYLATFLLSTFLMSFNLVEAVQPKIKLSDIVTPQPTEENQLATKRATTRLTQS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEHHHCCCCCCCCCHHHHHHHHHHHHHHH
HYRKFQLNDAFSEKIFERYLKSLDFSRNTFLQSDIDEMRAKYADKFDDALNEGDLSIAFA
HHHEEECCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
MYDLMMKRRYDRYKYALSLLDKEPDLSGQDQIEIDREKSPWPKDNAELDKLWEQRVKNDI
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEECCCCCCCCCCCCHHHHHHHHHHHHHH
INQKLKDKKWSDIKKRLIKRYDLAIRRLTQTKADDILQVYLNAFAREVDPHTSYLAPRTA
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCHHH
KSFNESMNLSLEGIGATLQQTEDDGTTIKSLVPGAPAERSKKLKAGDRIIGVGQASGEIE
HHHCCCCCEEEECCCCHHHCCCCCCCCHHHHCCCCCHHHHHHCCCCCCEEEECCCCCCHH
DVVGWRLEDIVDKIKGKKGTKVRLEIEPAKGGKSKIITLVRDKVRIEDQAAKLTISKVEG
HHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCHHEEHHHHHHHHCCHHHHHEEEEECCC
QIVASIKIPSFYIGLTQDVRKLLAEMKTKKAKALIIDLRDNGGGALTEAVGLSGLFISDG
EEEEEEECCEEEECCHHHHHHHHHHHHHCCCEEEEEEEECCCCCHHHHHHCCCEEEECCC
PIVQVRDAFQRIRVHEDPDSEQVYSGPLLVMINRFSASASEIFAAAMQDYNRGIIIGQNT
CEEHHHHHHHHCCCCCCCCCCHHHCCCEEEEEECCCCCHHHHHHHHHHHCCCCEEEECCC
FGKGTVQQSRSLNFAFDANQEPLGLIQYTIQKFYRIDGGSTQLKGVATDIDFPAAIDAKE
CCCCCHHHCCCCEEEECCCCCCHHHHHHHHHHHHCCCCCCCEECEEEECCCCCCCCCHHH
YGEEREDNALPWDKIPAANYFEVAQARDAVAFLTPKHIERIAKDPEFVALNEELKIRDER
CCCCCCCCCCCCCCCCCCCHHHHHHHCCHHEECCHHHHHHHHCCCCEEEECCCEEECCHH
NALKYLSLNYQKRKIENDKDDARRLKDLNARFKREGKKPLKDLDDLAKDYEAPDFYLKEA
HHHHHHHCCCHHHHCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHH
ERMAADLVQFETEKMGMNQKSTN
HHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]