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The map label for this gene is pepT

Identifier: 15602130

GI number: 15602130

Start: 298180

End: 299418

Strand: Direct

Name: pepT

Synonym: PM0265

Alternate gene names: 15602130

Gene position: 298180-299418 (Clockwise)

Preceding gene: 15602123

Following gene: 15602133

Centisome position: 13.21

GC content: 41.97

Gene sequence:

>1239_bases
ATGTTAAACCAACAGCAAACCTATAAGCTATTAGAACGCTTTTTACACTATACCACCTATGATACCCAGTCGAAAAGCGG
GGCGAAAATATCCCCGAGCTCAGCGGGACAATTAAAGCTTGCCAAGCATTTACAACAGGAATTATTCGCCCTCGGTTTAC
AAGATATTGACATCTCTAAACATTCCGTTGTGACAGCTTTTCTTCCTTCCAATGTCAATCCACATTCGCCAACCATTGGT
TTCATTGCGCATTTAGATACAGCAACACAATGTAGCGGTAAAAATGTGCAAGCCGAAGTGATTGAAAATTACCGTGGTGG
CGATATTGCGCTAGGGGTGGGCGAGGAGTTTATTAGCCCTGCGCATTATCAATTTTTACATCAACTGATTGGGAAAACGT
TAGTGGTTGCTGATGGCAATACTTTACTAGGTGCGGATAATAAAGCTGGTATTGCAGAAATTATGACCGCACTTGCGGTA
TTAAAAGAAGAAAATTTACCGCATTGTAACATTCGTGTTGCCTTTACGCCGGATGAAGAAATTGGTTTGGGGATGCAATT
TTTTCCTGTAGAAAAATTTCCGTGCGATTGGGCTTATACTATTGATGGTGGTGAAGTCGGTGAATTAGAGTATGAAAACT
TTAATGCCGCGACGGCGATTGTGACGATTGAAGGTGTAAATATGCACACAGGATCGGCAAAAGACAAAATGATTAATGCG
CTTACGCTTGCTTGTGAATTTCAGCAAGGTTTTCCAGCAGAGGAAACACCAGAGCAGACAGAAGGGAAACAGGGGTTTTA
CCATCTTAGTCACTTTACCGGACATGTGGAAAAAGTGGAATTGCAGTATTTAATTCGGGATTTCGACAGGGACGGATTTG
AGCAACGTAAAATTTTTATTCAGCAGCTTGTTGACCGGTTTAATCAACAAAAACGTTTAAAAAAGCCAATCACACTTGAA
ATTAAAGACAGTTATAAGAACATGAATGAAGTCGTGAAAACCGTGCCACAATCCGTTGAATTGGCGGATAGCGCGATGCG
AGAATGTGGCATTGAGCCGATTCATAAAGCGATTCGTGGGGGTACCGATGGCGCTTGGTTAGCGGAACAGGGATTAGCTT
GCCCAAATGTGTTTACGGGAGGATATAATTTTCACAGTAAACATGAGTTAATTACTTTAGAAGGGATGCAAAGTGCCGTC
AATGTGATAACGACGATTGTCAGACTGGCGACAAGCTAA

Upstream 100 bases:

>100_bases
GGGTTTTCACAAAATTAAAGCGAAAAGTTGTGATATGTCAATGAAGCTCAGATGATTTGTCGTTAGACTGAAACCATTCT
TTTATCAGCGAGCCAGTTTT

Downstream 100 bases:

>100_bases
ATAGATCAGAAAAAATTACAGATAAACATACCGCACTTGAGGATAAAAGTGCGGTATTTTTTTCGTTTATTTTGGTAAGG
CGCCCGAATTCCATTGTTGC

Product: peptidase T

Products: NA

Alternate protein names: Aminotripeptidase; Tripeptidase; Tripeptide aminopeptidase

Number of amino acids: Translated: 412; Mature: 412

Protein sequence:

>412_residues
MLNQQQTYKLLERFLHYTTYDTQSKSGAKISPSSAGQLKLAKHLQQELFALGLQDIDISKHSVVTAFLPSNVNPHSPTIG
FIAHLDTATQCSGKNVQAEVIENYRGGDIALGVGEEFISPAHYQFLHQLIGKTLVVADGNTLLGADNKAGIAEIMTALAV
LKEENLPHCNIRVAFTPDEEIGLGMQFFPVEKFPCDWAYTIDGGEVGELEYENFNAATAIVTIEGVNMHTGSAKDKMINA
LTLACEFQQGFPAEETPEQTEGKQGFYHLSHFTGHVEKVELQYLIRDFDRDGFEQRKIFIQQLVDRFNQQKRLKKPITLE
IKDSYKNMNEVVKTVPQSVELADSAMRECGIEPIHKAIRGGTDGAWLAEQGLACPNVFTGGYNFHSKHELITLEGMQSAV
NVITTIVRLATS

Sequences:

>Translated_412_residues
MLNQQQTYKLLERFLHYTTYDTQSKSGAKISPSSAGQLKLAKHLQQELFALGLQDIDISKHSVVTAFLPSNVNPHSPTIG
FIAHLDTATQCSGKNVQAEVIENYRGGDIALGVGEEFISPAHYQFLHQLIGKTLVVADGNTLLGADNKAGIAEIMTALAV
LKEENLPHCNIRVAFTPDEEIGLGMQFFPVEKFPCDWAYTIDGGEVGELEYENFNAATAIVTIEGVNMHTGSAKDKMINA
LTLACEFQQGFPAEETPEQTEGKQGFYHLSHFTGHVEKVELQYLIRDFDRDGFEQRKIFIQQLVDRFNQQKRLKKPITLE
IKDSYKNMNEVVKTVPQSVELADSAMRECGIEPIHKAIRGGTDGAWLAEQGLACPNVFTGGYNFHSKHELITLEGMQSAV
NVITTIVRLATS
>Mature_412_residues
MLNQQQTYKLLERFLHYTTYDTQSKSGAKISPSSAGQLKLAKHLQQELFALGLQDIDISKHSVVTAFLPSNVNPHSPTIG
FIAHLDTATQCSGKNVQAEVIENYRGGDIALGVGEEFISPAHYQFLHQLIGKTLVVADGNTLLGADNKAGIAEIMTALAV
LKEENLPHCNIRVAFTPDEEIGLGMQFFPVEKFPCDWAYTIDGGEVGELEYENFNAATAIVTIEGVNMHTGSAKDKMINA
LTLACEFQQGFPAEETPEQTEGKQGFYHLSHFTGHVEKVELQYLIRDFDRDGFEQRKIFIQQLVDRFNQQKRLKKPITLE
IKDSYKNMNEVVKTVPQSVELADSAMRECGIEPIHKAIRGGTDGAWLAEQGLACPNVFTGGYNFHSKHELITLEGMQSAV
NVITTIVRLATS

Specific function: Cleaves the N-terminal amino acid of tripeptides

COG id: COG2195

COG function: function code E; Di- and tripeptidases

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20B family

Homologues:

Organism=Escherichia coli, GI1787372, Length=401, Percent_Identity=54.3640897755611, Blast_Score=454, Evalue=1e-129,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PEPT_PASMU (Q9CP05)

Other databases:

- EMBL:   AE004439
- RefSeq:   NP_245202.1
- ProteinModelPortal:   Q9CP05
- SMR:   Q9CP05
- MEROPS:   M20.003
- GeneID:   1243612
- GenomeReviews:   AE004439_GR
- KEGG:   pmu:PM0265
- NMPDR:   fig|272843.1.peg.265
- HOGENOM:   HBG288638
- OMA:   HMDTAPD
- ProtClustDB:   PRK05469
- BioCyc:   PMUL272843:PM0265-MONOMER
- BRENDA:   3.4.11.4
- GO:   GO:0005737
- GO:   GO:0006508
- HAMAP:   MF_00550
- InterPro:   IPR001261
- InterPro:   IPR002933
- InterPro:   IPR011650
- InterPro:   IPR010161
- PIRSF:   PIRSF037215
- TIGRFAMs:   TIGR01882

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20; SSF55031 Peptidase_M20_dimer

EC number: =3.4.11.4

Molecular weight: Translated: 45632; Mature: 45632

Theoretical pI: Translated: 5.40; Mature: 5.40

Prosite motif: PS00758 ARGE_DAPE_CPG2_1; PS00759 ARGE_DAPE_CPG2_2; PS00079 MULTICOPPER_OXIDASE1

Important sites: ACT_SITE 86-86 ACT_SITE 179-179

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNQQQTYKLLERFLHYTTYDTQSKSGAKISPSSAGQLKLAKHLQQELFALGLQDIDISK
CCCHHHHHHHHHHHHHHHCCCCCCCCCCEECCCCCCHHHHHHHHHHHHHHCCCCCCCCCC
HSVVTAFLPSNVNPHSPTIGFIAHLDTATQCSGKNVQAEVIENYRGGDIALGVGEEFISP
CEEEEEECCCCCCCCCCCEEEEEECCCHHCCCCCCCHHHHHHCCCCCEEEEECCHHHHCH
AHYQFLHQLIGKTLVVADGNTLLGADNKAGIAEIMTALAVLKEENLPHCNIRVAFTPDEE
HHHHHHHHHHCCEEEEECCCEEECCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCHH
IGLGMQFFPVEKFPCDWAYTIDGGEVGELEYENFNAATAIVTIEGVNMHTGSAKDKMINA
HCCCEEEEECCCCCCCEEEEECCCCCCCEEECCCCCEEEEEEEECCEECCCCHHHHHHHH
LTLACEFQQGFPAEETPEQTEGKQGFYHLSHFTGHVEKVELQYLIRDFDRDGFEQRKIFI
HHEEEECCCCCCCCCCCCCCCCCCCEEEHHHHHCCHHHHHHHHHHHHHCCCCHHHHHHHH
QQLVDRFNQQKRLKKPITLEIKDSYKNMNEVVKTVPQSVELADSAMRECGIEPIHKAIRG
HHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHC
GTDGAWLAEQGLACPNVFTGGYNFHSKHELITLEGMQSAVNVITTIVRLATS
CCCCCHHHHCCCCCCCEEECCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLNQQQTYKLLERFLHYTTYDTQSKSGAKISPSSAGQLKLAKHLQQELFALGLQDIDISK
CCCHHHHHHHHHHHHHHHCCCCCCCCCCEECCCCCCHHHHHHHHHHHHHHCCCCCCCCCC
HSVVTAFLPSNVNPHSPTIGFIAHLDTATQCSGKNVQAEVIENYRGGDIALGVGEEFISP
CEEEEEECCCCCCCCCCCEEEEEECCCHHCCCCCCCHHHHHHCCCCCEEEEECCHHHHCH
AHYQFLHQLIGKTLVVADGNTLLGADNKAGIAEIMTALAVLKEENLPHCNIRVAFTPDEE
HHHHHHHHHHCCEEEEECCCEEECCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCHH
IGLGMQFFPVEKFPCDWAYTIDGGEVGELEYENFNAATAIVTIEGVNMHTGSAKDKMINA
HCCCEEEEECCCCCCCEEEEECCCCCCCEEECCCCCEEEEEEEECCEECCCCHHHHHHHH
LTLACEFQQGFPAEETPEQTEGKQGFYHLSHFTGHVEKVELQYLIRDFDRDGFEQRKIFI
HHEEEECCCCCCCCCCCCCCCCCCCEEEHHHHHCCHHHHHHHHHHHHHCCCCHHHHHHHH
QQLVDRFNQQKRLKKPITLEIKDSYKNMNEVVKTVPQSVELADSAMRECGIEPIHKAIRG
HHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHC
GTDGAWLAEQGLACPNVFTGGYNFHSKHELITLEGMQSAVNVITTIVRLATS
CCCCCHHHHCCCCCCCEEECCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11248100