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The map label for this gene is cdd

Identifier: 15602124

GI number: 15602124

Start: 291653

End: 292537

Strand: Reverse

Name: cdd

Synonym: PM0259

Alternate gene names: 15602124

Gene position: 292537-291653 (Counterclockwise)

Preceding gene: 15602125

Following gene: 15602118

Centisome position: 12.96

GC content: 39.55

Gene sequence:

>885_bases
ATTTCAGAGAAAATCCGAAAAACACTCTCACTAATTGAGTCCCAACAATTAGCACAAGATGTATGGCATATTTTGCAAGA
ACAACATTTTAAAGGCATGTTACCTTATTTTACGGTTGAACATCTTTGTACTAAACATCAGCTTACACCACAACAACTCG
CACTTAAGCTCTTACCAATTGCAGCAGCTTACTCTCTCGCTCCAATTTCCCAATTTCATGTTGGGGCTATTGCGATTGGA
CAACGTGGTGCATATTATTTCGGTGCGAATTTAGAGTTTGCCTCGACCCATATTCAACAAACCGTCCATGCTGAACAAAG
TGCGATTTCTCATGCTTGGATGAATCACGAAAGTGCAATTACCGATGTGGTCGTCAACTATACGCCATGTGGTCATTGTC
GCCAATTTATGAATGAATTAAAAACCGCCCCGCAGTTAAAAATTCATTTACCACACAGTCAAAATAACTTATTACATAGC
TATTTACCTGATGCATTTGGTCCGGCTGATTTGGATATTCAGCACTTTTTATTAGATGCACAAAATAACCAGCTTACATA
TGAAACGCAAGATCCTGTCATGTTGACCGCACTTGAATGTGCCAATGCCGCACATGCACCTTATTCGAAGTCATATCACG
GCATCGCTATTGAAACAAAAGATAAACAAATTTATCGGGGCAGTTATGCGGAAAATGCCGCATTTAACCCAAGTTTACCA
GCATTACAGGTCGCACTAAATCACCTTTTACTCAGTGGTGATACCTTACAAAATATCCAACGTATTGTCATGATCGAAAA
AGCAAATCACTTATGCTATCGCCATATGGCTGAAGATTTAGTTGCCAACCTCGTTGATATCCCACTTGATTATATTGCGC
TGTAA

Upstream 100 bases:

>100_bases
TGATTTGTATCATAAAAAGATCTTCTGAATGAAGATCTTTTTTTTCTGTTGCATTAAGATGAGGTCATGCATGATGAGAA
GGAGAAACATAATGATCCCA

Downstream 100 bases:

>100_bases
ACCACACAAAAATAGAATGAAAAAAGCGGTCACCTCTTTAACAAGGGACCGCTTTTTTAAACGCGAAATGACTAACCAAT
CTGTGCTAACCCGCCCATAT

Product: cytidine deaminase

Products: NA

Alternate protein names: Cytidine aminohydrolase; CDA

Number of amino acids: Translated: 294; Mature: 293

Protein sequence:

>294_residues
MSEKIRKTLSLIESQQLAQDVWHILQEQHFKGMLPYFTVEHLCTKHQLTPQQLALKLLPIAAAYSLAPISQFHVGAIAIG
QRGAYYFGANLEFASTHIQQTVHAEQSAISHAWMNHESAITDVVVNYTPCGHCRQFMNELKTAPQLKIHLPHSQNNLLHS
YLPDAFGPADLDIQHFLLDAQNNQLTYETQDPVMLTALECANAAHAPYSKSYHGIAIETKDKQIYRGSYAENAAFNPSLP
ALQVALNHLLLSGDTLQNIQRIVMIEKANHLCYRHMAEDLVANLVDIPLDYIAL

Sequences:

>Translated_294_residues
MSEKIRKTLSLIESQQLAQDVWHILQEQHFKGMLPYFTVEHLCTKHQLTPQQLALKLLPIAAAYSLAPISQFHVGAIAIG
QRGAYYFGANLEFASTHIQQTVHAEQSAISHAWMNHESAITDVVVNYTPCGHCRQFMNELKTAPQLKIHLPHSQNNLLHS
YLPDAFGPADLDIQHFLLDAQNNQLTYETQDPVMLTALECANAAHAPYSKSYHGIAIETKDKQIYRGSYAENAAFNPSLP
ALQVALNHLLLSGDTLQNIQRIVMIEKANHLCYRHMAEDLVANLVDIPLDYIAL
>Mature_293_residues
SEKIRKTLSLIESQQLAQDVWHILQEQHFKGMLPYFTVEHLCTKHQLTPQQLALKLLPIAAAYSLAPISQFHVGAIAIGQ
RGAYYFGANLEFASTHIQQTVHAEQSAISHAWMNHESAITDVVVNYTPCGHCRQFMNELKTAPQLKIHLPHSQNNLLHSY
LPDAFGPADLDIQHFLLDAQNNQLTYETQDPVMLTALECANAAHAPYSKSYHGIAIETKDKQIYRGSYAENAAFNPSLPA
LQVALNHLLLSGDTLQNIQRIVMIEKANHLCYRHMAEDLVANLVDIPLDYIAL

Specific function: This enzyme scavenge exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis

COG id: COG0295

COG function: function code F; Cytidine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family

Homologues:

Organism=Escherichia coli, GI1788465, Length=246, Percent_Identity=52.4390243902439, Blast_Score=230, Evalue=7e-62,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CDD_PASMU (Q9CP11)

Other databases:

- EMBL:   AE004439
- RefSeq:   NP_245196.1
- ProteinModelPortal:   Q9CP11
- SMR:   Q9CP11
- GeneID:   1243606
- GenomeReviews:   AE004439_GR
- KEGG:   pmu:PM0259
- NMPDR:   fig|272843.1.peg.259
- HOGENOM:   HBG591160
- OMA:   NRSHAPY
- ProtClustDB:   PRK09027
- BioCyc:   PMUL272843:PM0259-MONOMER
- BRENDA:   3.5.4.5
- HAMAP:   MF_01558
- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR013171
- InterPro:   IPR006263
- InterPro:   IPR016193
- InterPro:   IPR020797
- PIRSF:   PIRSF006334
- TIGRFAMs:   TIGR01355

Pfam domain/function: PF00383 dCMP_cyt_deam_1; PF08211 dCMP_cyt_deam_2; SSF53927 Cytidine_deaminase-like

EC number: =3.5.4.5

Molecular weight: Translated: 32994; Mature: 32863

Theoretical pI: Translated: 6.55; Mature: 6.55

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: ACT_SITE 105-105

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEKIRKTLSLIESQQLAQDVWHILQEQHFKGMLPYFTVEHLCTKHQLTPQQLALKLLPI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHHHH
AAAYSLAPISQFHVGAIAIGQRGAYYFGANLEFASTHIQQTVHAEQSAISHAWMNHESAI
HHHHHHCCHHHHCCCEEEECCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
TDVVVNYTPCGHCRQFMNELKTAPQLKIHLPHSQNNLLHSYLPDAFGPADLDIQHFLLDA
HHHEEECCCCHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHCCCCCCCCCCCHHHHEEEC
QNNQLTYETQDPVMLTALECANAAHAPYSKSYHGIAIETKDKQIYRGSYAENAAFNPSLP
CCCEEEEECCCCEEEEHHHHCCCCCCCCCCCCCCEEEEECCCCEECCCCCCCCCCCCCCH
ALQVALNHLLLSGDTLQNIQRIVMIEKANHLCYRHMAEDLVANLVDIPLDYIAL
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCC
>Mature Secondary Structure 
SEKIRKTLSLIESQQLAQDVWHILQEQHFKGMLPYFTVEHLCTKHQLTPQQLALKLLPI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHHHH
AAAYSLAPISQFHVGAIAIGQRGAYYFGANLEFASTHIQQTVHAEQSAISHAWMNHESAI
HHHHHHCCHHHHCCCEEEECCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
TDVVVNYTPCGHCRQFMNELKTAPQLKIHLPHSQNNLLHSYLPDAFGPADLDIQHFLLDA
HHHEEECCCCHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHCCCCCCCCCCCHHHHEEEC
QNNQLTYETQDPVMLTALECANAAHAPYSKSYHGIAIETKDKQIYRGSYAENAAFNPSLP
CCCEEEEECCCCEEEEHHHHCCCCCCCCCCCCCCEEEEECCCCEECCCCCCCCCCCCCCH
ALQVALNHLLLSGDTLQNIQRIVMIEKANHLCYRHMAEDLVANLVDIPLDYIAL
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11248100