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The map label for this gene is plsC [H]

Identifier: 15601968

GI number: 15601968

Start: 127389

End: 128114

Strand: Direct

Name: plsC [H]

Synonym: PM0103

Alternate gene names: 15601968

Gene position: 127389-128114 (Clockwise)

Preceding gene: 15601965

Following gene: 15601969

Centisome position: 5.64

GC content: 41.05

Gene sequence:

>726_bases
ATGTTAAAATTATTACGTACAATCGTTATTGTTTTTTGTTGTCTCTTAATTTGTGTGTTGGGGTCAATTTACTCCTTTAT
CCGCTTTCGTAATCCAAGCAATGTGGGCATTATGGCGCGTTGGTTTGGACGTCTTCATCCTCTCTTTGGCTTAACCGTAG
AGCATCGTTTCCCTAAAAATGTCGATAAATTCGGGCGCTGTATTTATATTGGTAATCACCAGAATAATTATGACATGGTC
ACGATTTCTTATATGGTACAACCAAGAACGGTGAGTGTGGGTAAGAAAAGTTTAATTTGGATACCTTTTTTTGGACTGTT
GTATTGGGTTACTGGCAATATTCTGATTGATCGTGAAAATCGTACTAAAGCGCACGGCACGATGAACGAAGTTGCTCGCC
GTATTCATGATGATGACCTATCGGTGTGGATGTTCCCAGAAGGGACGCGTAGTCGAGGACGTGGCTTATTGCCTTTTAAA
ACGGGGGCATTTTATGCGGCGATTGCGGCAGGTGTACCGATTGTTCCAGTAGTATGCTCAACGACACAAGGCAAGATCGA
TTTAAATCGTTGGGATAATGGCAAAGTGATTTGTGAAATGTTAGAACCGATAGATGTTTCTGCTTATGATAAAGAAAATG
TGCGTGAACTAGCAGCACATTGCCATCAGCTCATGGCACAACGTATTGCTGAACTTGATGCTGAAATAGCACAACAGAGT
AAATAA

Upstream 100 bases:

>100_bases
CATGTCTTTTTTATTTAGAGTAGCACATTTTTTATGTTGATTTATACACATATTCCGGCAATTTCGCTATACTTAGCCAA
ATATTTCAAGGAATAGCATT

Downstream 100 bases:

>100_bases
AGAATGGATAATCCGGCGCGTCGACAGTTTTTCAAAACCAGTTTAATTGCCACGGCACTTTCAGCCTTGCCATCCTCTCT
CTTGGCTGCAACACGCCAAG

Product: hypothetical protein

Products: NA

Alternate protein names: 1-AGP acyltransferase; 1-AGPAT; Lysophosphatidic acid acyltransferase; LPAAT [H]

Number of amino acids: Translated: 241; Mature: 241

Protein sequence:

>241_residues
MLKLLRTIVIVFCCLLICVLGSIYSFIRFRNPSNVGIMARWFGRLHPLFGLTVEHRFPKNVDKFGRCIYIGNHQNNYDMV
TISYMVQPRTVSVGKKSLIWIPFFGLLYWVTGNILIDRENRTKAHGTMNEVARRIHDDDLSVWMFPEGTRSRGRGLLPFK
TGAFYAAIAAGVPIVPVVCSTTQGKIDLNRWDNGKVICEMLEPIDVSAYDKENVRELAAHCHQLMAQRIAELDAEIAQQS
K

Sequences:

>Translated_241_residues
MLKLLRTIVIVFCCLLICVLGSIYSFIRFRNPSNVGIMARWFGRLHPLFGLTVEHRFPKNVDKFGRCIYIGNHQNNYDMV
TISYMVQPRTVSVGKKSLIWIPFFGLLYWVTGNILIDRENRTKAHGTMNEVARRIHDDDLSVWMFPEGTRSRGRGLLPFK
TGAFYAAIAAGVPIVPVVCSTTQGKIDLNRWDNGKVICEMLEPIDVSAYDKENVRELAAHCHQLMAQRIAELDAEIAQQS
K
>Mature_241_residues
MLKLLRTIVIVFCCLLICVLGSIYSFIRFRNPSNVGIMARWFGRLHPLFGLTVEHRFPKNVDKFGRCIYIGNHQNNYDMV
TISYMVQPRTVSVGKKSLIWIPFFGLLYWVTGNILIDRENRTKAHGTMNEVARRIHDDDLSVWMFPEGTRSRGRGLLPFK
TGAFYAAIAAGVPIVPVVCSTTQGKIDLNRWDNGKVICEMLEPIDVSAYDKENVRELAAHCHQLMAQRIAELDAEIAQQS
K

Specific function: Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating acyl moiety at the 2 position [H]

COG id: COG0204

COG function: function code I; 1-acyl-sn-glycerol-3-phosphate acyltransferase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI6041665, Length=224, Percent_Identity=32.5892857142857, Blast_Score=125, Evalue=3e-29,
Organism=Homo sapiens, GI5453718, Length=223, Percent_Identity=31.390134529148, Blast_Score=117, Evalue=7e-27,
Organism=Homo sapiens, GI15100175, Length=223, Percent_Identity=31.390134529148, Blast_Score=117, Evalue=7e-27,
Organism=Escherichia coli, GI1789395, Length=240, Percent_Identity=64.1666666666667, Blast_Score=323, Evalue=6e-90,
Organism=Caenorhabditis elegans, GI17564032, Length=179, Percent_Identity=32.4022346368715, Blast_Score=109, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI17568319, Length=236, Percent_Identity=30.5084745762712, Blast_Score=107, Evalue=5e-24,
Organism=Saccharomyces cerevisiae, GI6320151, Length=239, Percent_Identity=30.9623430962343, Blast_Score=105, Evalue=5e-24,
Organism=Drosophila melanogaster, GI281364648, Length=234, Percent_Identity=31.1965811965812, Blast_Score=122, Evalue=3e-28,
Organism=Drosophila melanogaster, GI24582856, Length=234, Percent_Identity=31.1965811965812, Blast_Score=122, Evalue=3e-28,
Organism=Drosophila melanogaster, GI24582854, Length=234, Percent_Identity=31.1965811965812, Blast_Score=122, Evalue=3e-28,
Organism=Drosophila melanogaster, GI24641614, Length=207, Percent_Identity=31.8840579710145, Blast_Score=110, Evalue=6e-25,
Organism=Drosophila melanogaster, GI24641612, Length=207, Percent_Identity=31.8840579710145, Blast_Score=110, Evalue=6e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002123
- InterPro:   IPR004552 [H]

Pfam domain/function: PF01553 Acyltransferase [H]

EC number: =2.3.1.51 [H]

Molecular weight: Translated: 27447; Mature: 27447

Theoretical pI: Translated: 9.26; Mature: 9.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKLLRTIVIVFCCLLICVLGSIYSFIRFRNPSNVGIMARWFGRLHPLFGLTVEHRFPKN
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCEECCCCCCC
VDKFGRCIYIGNHQNNYDMVTISYMVQPRTVSVGKKSLIWIPFFGLLYWVTGNILIDREN
HHHHCCEEEECCCCCCCEEEEEEEEECCEEECCCCCEEEEHHHHHHHHHHHCCEEEECCC
RTKAHGTMNEVARRIHDDDLSVWMFPEGTRSRGRGLLPFKTGAFYAAIAAGVPIVPVVCS
CCCCCCCHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCCCCHHHHHHHCCCCEEEEEEC
TTQGKIDLNRWDNGKVICEMLEPIDVSAYDKENVRELAAHCHQLMAQRIAELDAEIAQQS
CCCCEEEECCCCCCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
K
C
>Mature Secondary Structure
MLKLLRTIVIVFCCLLICVLGSIYSFIRFRNPSNVGIMARWFGRLHPLFGLTVEHRFPKN
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCEECCCCCCC
VDKFGRCIYIGNHQNNYDMVTISYMVQPRTVSVGKKSLIWIPFFGLLYWVTGNILIDREN
HHHHCCEEEECCCCCCCEEEEEEEEECCEEECCCCCEEEEHHHHHHHHHHHCCEEEECCC
RTKAHGTMNEVARRIHDDDLSVWMFPEGTRSRGRGLLPFKTGAFYAAIAAGVPIVPVVCS
CCCCCCCHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCCCCHHHHHHHCCCCEEEEEEC
TTQGKIDLNRWDNGKVICEMLEPIDVSAYDKENVRELAAHCHQLMAQRIAELDAEIAQQS
CCCCEEEECCCCCCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
K
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]