Click here to switch to the map view.

The map label for this gene is ars [H]

Identifier: 15601904

GI number: 15601904

Start: 39720

End: 40703

Strand: Reverse

Name: ars [H]

Synonym: PM0039

Alternate gene names: 15601904

Gene position: 40703-39720 (Counterclockwise)

Preceding gene: 15601905

Following gene: 15601903

Centisome position: 1.8

GC content: 42.17

Gene sequence:

>984_bases
ATGAAAAAGAGTAACATTATTTTATTTCTGAGTTTATCTCTCTTTTCTCTCACCACTATTGCACAGCAATGCACTCACCA
AGATTTAGATGTGGTTGTACTCGGTTCTGGTGGACCTGAGATTCAATTATTCCGTAACAATCCTTCCCCTCCACCGAGAG
CTTCAGCAAGTTATTTAGTGCGAGAAAATGGAAAAGCCGCATTTTTAGTGGATTTCGGCACTGGTGCTTTGCAAAATTTT
GCACGTTCAGGCGCCAAAATTGAAGATGTAAAAGGGATTTTAATTACTCATTTCCATGTGGATCATATTAACGATCTGCC
TGCACTTGTGAAAGCCTCTTTCTTTTCTTCACGTCATCATGACTTAGCTATTTATGGACCAACGGGCAATGAATTCATTC
CAGATACCGAACAATTTATCACCCGCTTACTCGGTGAAAAAGGGGCTTATAGTTATCTCTCTGGTTTTTTAACGGGCGAT
GAATCCTATCAAATTCAACCAACCTCTGTGCCTGCTGATAAAACCGCCCCTATGCACTTTCACACCGAGATCGACGGTTT
TCAACTGTCTGCTATCGCGACAGAACATGGCTTACTTCCCGCTCTGGCTTGGCGTATCGAAAAAGGCGGATGCCGTATTG
TGTTTTCTGGCGATACCAGTAATCAAGGCAACAGCTTAGATCGCTTGGTGCAAGAGGCAGATCTCTTTATTGCACATAAT
GCGGTGCCCGAAACGAGCCAAGATAATGTTGCAAATAAACTCCATATGCGCCCTTCCGAAATTGCTCGAATTGCCCAACA
AGGCAACGTAAAAAACTTGTTATTAAGCCATCTCATGCGCCGTACTGAACACGTCAAAGCACAAACCAAAAACATAATCC
AAGCACGATTTGACGGAAAAATTGCGTTTGCTAATGATTGTGATGTGTACGCTGTTGCAACAGGGATAAGAAAAGGTCAA
TGTGACAATAAAATCAGTGATTAA

Upstream 100 bases:

>100_bases
TTGACGACAAACGAAAAGTGCGGTCTTTTTTTGTCATTTTTCGCACACAAAATGACGTGTTATACCTGCTTTATGCTTTC
CATGGAGACAAGATCACTTT

Downstream 100 bases:

>100_bases
TATGGCATGACTTATAACTTTTTTATCTAATAAGATTTTGTTTTTTTATGTTGAAAATTTCTACATTATAGTGTTAAATC
GGCATATTTTATAAGGTTAT

Product: Ars

Products: NA

Alternate protein names: RNase Z; tRNA 3 endonuclease; tRNase Z [H]

Number of amino acids: Translated: 327; Mature: 327

Protein sequence:

>327_residues
MKKSNIILFLSLSLFSLTTIAQQCTHQDLDVVVLGSGGPEIQLFRNNPSPPPRASASYLVRENGKAAFLVDFGTGALQNF
ARSGAKIEDVKGILITHFHVDHINDLPALVKASFFSSRHHDLAIYGPTGNEFIPDTEQFITRLLGEKGAYSYLSGFLTGD
ESYQIQPTSVPADKTAPMHFHTEIDGFQLSAIATEHGLLPALAWRIEKGGCRIVFSGDTSNQGNSLDRLVQEADLFIAHN
AVPETSQDNVANKLHMRPSEIARIAQQGNVKNLLLSHLMRRTEHVKAQTKNIIQARFDGKIAFANDCDVYAVATGIRKGQ
CDNKISD

Sequences:

>Translated_327_residues
MKKSNIILFLSLSLFSLTTIAQQCTHQDLDVVVLGSGGPEIQLFRNNPSPPPRASASYLVRENGKAAFLVDFGTGALQNF
ARSGAKIEDVKGILITHFHVDHINDLPALVKASFFSSRHHDLAIYGPTGNEFIPDTEQFITRLLGEKGAYSYLSGFLTGD
ESYQIQPTSVPADKTAPMHFHTEIDGFQLSAIATEHGLLPALAWRIEKGGCRIVFSGDTSNQGNSLDRLVQEADLFIAHN
AVPETSQDNVANKLHMRPSEIARIAQQGNVKNLLLSHLMRRTEHVKAQTKNIIQARFDGKIAFANDCDVYAVATGIRKGQ
CDNKISD
>Mature_327_residues
MKKSNIILFLSLSLFSLTTIAQQCTHQDLDVVVLGSGGPEIQLFRNNPSPPPRASASYLVRENGKAAFLVDFGTGALQNF
ARSGAKIEDVKGILITHFHVDHINDLPALVKASFFSSRHHDLAIYGPTGNEFIPDTEQFITRLLGEKGAYSYLSGFLTGD
ESYQIQPTSVPADKTAPMHFHTEIDGFQLSAIATEHGLLPALAWRIEKGGCRIVFSGDTSNQGNSLDRLVQEADLFIAHN
AVPETSQDNVANKLHMRPSEIARIAQQGNVKNLLLSHLMRRTEHVKAQTKNIIQARFDGKIAFANDCDVYAVATGIRKGQ
CDNKISD

Specific function: Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA [H]

COG id: COG1234

COG function: function code R; Metal-dependent hydrolases of the beta-lactamase superfamily III

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNase Z family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001279
- InterPro:   IPR013471 [H]

Pfam domain/function: PF00753 Lactamase_B [H]

EC number: =3.1.26.11 [H]

Molecular weight: Translated: 35854; Mature: 35854

Theoretical pI: Translated: 7.00; Mature: 7.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKSNIILFLSLSLFSLTTIAQQCTHQDLDVVVLGSGGPEIQLFRNNPSPPPRASASYLV
CCCCCEEEEEEHHHHHHHHHHHHHCCCCCCEEEECCCCCEEEEEECCCCCCCCCCCEEEE
RENGKAAFLVDFGTGALQNFARSGAKIEDVKGILITHFHVDHINDLPALVKASFFSSRHH
ECCCCEEEEEECCCHHHHHHHHCCCEEECCCEEEEEEEECCCCCCHHHHHHHHHHCCCCC
DLAIYGPTGNEFIPDTEQFITRLLGEKGAYSYLSGFLTGDESYQIQPTSVPADKTAPMHF
CEEEECCCCCCCCCCHHHHHHHHHCCCCCHHHHHHEECCCCCEEEEECCCCCCCCCCEEE
HTEIDGFQLSAIATEHGLLPALAWRIEKGGCRIVFSGDTSNQGNSLDRLVQEADLFIAHN
EECCCCEEEEEEECCCCCHHHHHEEEECCCEEEEECCCCCCCCCHHHHHHHHHHEEEEEC
AVPETSQDNVANKLHMRPSEIARIAQQGNVKNLLLSHLMRRTEHVKAQTKNIIQARFDGK
CCCCCCCCCHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCE
IAFANDCDVYAVATGIRKGQCDNKISD
EEEECCCCEEEEECCCCCCCCCCCCCC
>Mature Secondary Structure
MKKSNIILFLSLSLFSLTTIAQQCTHQDLDVVVLGSGGPEIQLFRNNPSPPPRASASYLV
CCCCCEEEEEEHHHHHHHHHHHHHCCCCCCEEEECCCCCEEEEEECCCCCCCCCCCEEEE
RENGKAAFLVDFGTGALQNFARSGAKIEDVKGILITHFHVDHINDLPALVKASFFSSRHH
ECCCCEEEEEECCCHHHHHHHHCCCEEECCCEEEEEEEECCCCCCHHHHHHHHHHCCCCC
DLAIYGPTGNEFIPDTEQFITRLLGEKGAYSYLSGFLTGDESYQIQPTSVPADKTAPMHF
CEEEECCCCCCCCCCHHHHHHHHHCCCCCHHHHHHEECCCCCEEEEECCCCCCCCCCEEE
HTEIDGFQLSAIATEHGLLPALAWRIEKGGCRIVFSGDTSNQGNSLDRLVQEADLFIAHN
EECCCCEEEEEEECCCCCHHHHHEEEECCCEEEEECCCCCCCCCHHHHHHHHHHEEEEEC
AVPETSQDNVANKLHMRPSEIARIAQQGNVKNLLLSHLMRRTEHVKAQTKNIIQARFDGK
CCCCCCCCCHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCE
IAFANDCDVYAVATGIRKGQCDNKISD
EEEECCCCEEEEECCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]