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The map label for this gene is sdaC [H]

Identifier: 15601902

GI number: 15601902

Start: 37268

End: 38509

Strand: Reverse

Name: sdaC [H]

Synonym: PM0037

Alternate gene names: 15601902

Gene position: 38509-37268 (Counterclockwise)

Preceding gene: 15601903

Following gene: 15601901

Centisome position: 1.71

GC content: 39.13

Gene sequence:

>1242_bases
ATGGCAACAAAATCTTGTGTCAGTTGGAGCAAGTTTGATCTTGTCTGGGCATTAAATTTATTCGGTACCGCTGTGGGTGC
GGGTGTCTTATTTTTACCCATTAATGCAGGAAAAGGCGGGTTTTGGCCCTTAGTATGTATGACACTCCTAGTAGGTCCCA
TGACTTACTTAGCACACCGCGGACTCACTCGTTTTGTCCTATCTTCTGCCAAAAGCGGCAGTGATATTACTGAAGTCGTA
GAAGAACATTTTGGGCAAACCGCAGGAAAATTCATTACTTTACTTTATTTCTTTGCGATTTTTCCTATTCTGCTGATTTA
TGGTAACGGAATAACTAACACAGTCGATTCATTTATTGTACATCAACTGCATATGAACTCACCTAATCGCGCCTTATTGG
CTTTCATCCTCATTGCCGGCTTAATTTCTGTTATGTTAATGAACGAGAAGATCATGCTAAAAATTACCGAGTTTTTAGTC
TATCCATTAGTCTGTATTCTGCTCGCCTTATCACTCTATCTTATTCCGGAATGGAATACCTCAATGTTAACAGAATTTCC
GAGTACGCAAGCCCTATTCAGCACCTTATGGATTACGATCCCTGTATTGGTTTTTTCGTTTAACCACTCACCGGCTATTT
CATCTTTTGCCCAATCTCAACAACGTGAATATGGTGATCTCACAAACACAGAAACGCATACTAACCGCACTTTAAAAATA
ACCTCAAGTATTTTGCTGGTGTTTGTGATGTTCTTCGTTTTTAGCTGTGTATTAAGTTTAACTCCTGCTGAATTAGCACA
AGCAAAAACACAAAATATCAGTATCTTATCCTTCCTCGCCAACAAATTTGATAATCCTTATATTTCTTACCTTGGACCTT
TCGTTGCCTTCTTGGCAATTACTAGCTCTTTCTTTGGTCACTATCTCGGTGCAAAAGAAGGACTAGAAGGGTTAATTATC
AAAATGTCTGGCAAAAAAGAGATTAAGTGTCAAAAATTAAATTATTTCACCGCACTTTTCTTCTTGCTAACCCTGTGGAT
TGTCGCCATTATTAATCCAAGTATTCTTGGCTTAATAGAATCCTTCGGCGGACCGATTATTGCTGCAATTTTATTTATCA
TGCCGATGTATGCGATCCGTAAAATTCCCGCGATGCAACGTTACCAAGGACGCTTTTCGAATCTCTTCGTTACCATCATG
GGTATGTTCGCCATCTCAGCGGTTGTTTATGGCTTATTTTAA

Upstream 100 bases:

>100_bases
TAATTTCACATTGAGTTTTCCCCACAATCTCTCTACTATAAATCTCCTCTTATTCTAGCGCTTTGGCGCTATTTGTTTTT
TCAATAACATGGAGCGTTTT

Downstream 100 bases:

>100_bases
TTCGGCAAAATCCGTGTAGAATAGCCTCCCTTTTACGCTAAAGAAAAGTAGAAATGTATGATTAGTGTTTTTGATATGTT
TAAAATTGGTATCGGTCCCT

Product: SdaC

Products: Proton [Cytoplasm]; D-serine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 413; Mature: 412

Protein sequence:

>413_residues
MATKSCVSWSKFDLVWALNLFGTAVGAGVLFLPINAGKGGFWPLVCMTLLVGPMTYLAHRGLTRFVLSSAKSGSDITEVV
EEHFGQTAGKFITLLYFFAIFPILLIYGNGITNTVDSFIVHQLHMNSPNRALLAFILIAGLISVMLMNEKIMLKITEFLV
YPLVCILLALSLYLIPEWNTSMLTEFPSTQALFSTLWITIPVLVFSFNHSPAISSFAQSQQREYGDLTNTETHTNRTLKI
TSSILLVFVMFFVFSCVLSLTPAELAQAKTQNISILSFLANKFDNPYISYLGPFVAFLAITSSFFGHYLGAKEGLEGLII
KMSGKKEIKCQKLNYFTALFFLLTLWIVAIINPSILGLIESFGGPIIAAILFIMPMYAIRKIPAMQRYQGRFSNLFVTIM
GMFAISAVVYGLF

Sequences:

>Translated_413_residues
MATKSCVSWSKFDLVWALNLFGTAVGAGVLFLPINAGKGGFWPLVCMTLLVGPMTYLAHRGLTRFVLSSAKSGSDITEVV
EEHFGQTAGKFITLLYFFAIFPILLIYGNGITNTVDSFIVHQLHMNSPNRALLAFILIAGLISVMLMNEKIMLKITEFLV
YPLVCILLALSLYLIPEWNTSMLTEFPSTQALFSTLWITIPVLVFSFNHSPAISSFAQSQQREYGDLTNTETHTNRTLKI
TSSILLVFVMFFVFSCVLSLTPAELAQAKTQNISILSFLANKFDNPYISYLGPFVAFLAITSSFFGHYLGAKEGLEGLII
KMSGKKEIKCQKLNYFTALFFLLTLWIVAIINPSILGLIESFGGPIIAAILFIMPMYAIRKIPAMQRYQGRFSNLFVTIM
GMFAISAVVYGLF
>Mature_412_residues
ATKSCVSWSKFDLVWALNLFGTAVGAGVLFLPINAGKGGFWPLVCMTLLVGPMTYLAHRGLTRFVLSSAKSGSDITEVVE
EHFGQTAGKFITLLYFFAIFPILLIYGNGITNTVDSFIVHQLHMNSPNRALLAFILIAGLISVMLMNEKIMLKITEFLVY
PLVCILLALSLYLIPEWNTSMLTEFPSTQALFSTLWITIPVLVFSFNHSPAISSFAQSQQREYGDLTNTETHTNRTLKIT
SSILLVFVMFFVFSCVLSLTPAELAQAKTQNISILSFLANKFDNPYISYLGPFVAFLAITSSFFGHYLGAKEGLEGLIIK
MSGKKEIKCQKLNYFTALFFLLTLWIVAIINPSILGLIESFGGPIIAAILFIMPMYAIRKIPAMQRYQGRFSNLFVTIMG
MFAISAVVYGLF

Specific function: Involved in the import of serine into the cell [H]

COG id: COG0814

COG function: function code E; Amino acid permeases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid/polyamine transporter 2 family. SdaC/TdcC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789160, Length=420, Percent_Identity=57.6190476190476, Blast_Score=469, Evalue=1e-133,
Organism=Escherichia coli, GI1789504, Length=428, Percent_Identity=42.9906542056075, Blast_Score=340, Evalue=1e-94,
Organism=Escherichia coli, GI1789211, Length=404, Percent_Identity=35.8910891089109, Blast_Score=239, Evalue=2e-64,
Organism=Escherichia coli, GI1789961, Length=387, Percent_Identity=25.0645994832041, Blast_Score=129, Evalue=3e-31,
Organism=Escherichia coli, GI145693183, Length=400, Percent_Identity=24, Blast_Score=123, Evalue=2e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004694
- InterPro:   IPR018227 [H]

Pfam domain/function: PF03222 Trp_Tyr_perm [H]

EC number: NA

Molecular weight: Translated: 45861; Mature: 45730

Theoretical pI: Translated: 9.05; Mature: 9.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATKSCVSWSKFDLVWALNLFGTAVGAGVLFLPINAGKGGFWPLVCMTLLVGPMTYLAHR
CCCCHHCCHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHC
GLTRFVLSSAKSGSDITEVVEEHFGQTAGKFITLLYFFAIFPILLIYGNGITNTVDSFIV
CHHHHHHHHCCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
HQLHMNSPNRALLAFILIAGLISVMLMNEKIMLKITEFLVYPLVCILLALSLYLIPEWNT
HHHHCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
SMLTEFPSTQALFSTLWITIPVLVFSFNHSPAISSFAQSQQREYGDLTNTETHTNRTLKI
HHHHHCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHH
TSSILLVFVMFFVFSCVLSLTPAELAQAKTQNISILSFLANKFDNPYISYLGPFVAFLAI
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHHHH
TSSFFGHYLGAKEGLEGLIIKMSGKKEIKCQKLNYFTALFFLLTLWIVAIINPSILGLIE
HHHHHHHHHCHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHH
SFGGPIIAAILFIMPMYAIRKIPAMQRYQGRFSNLFVTIMGMFAISAVVYGLF
HHCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
ATKSCVSWSKFDLVWALNLFGTAVGAGVLFLPINAGKGGFWPLVCMTLLVGPMTYLAHR
CCCHHCCHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHC
GLTRFVLSSAKSGSDITEVVEEHFGQTAGKFITLLYFFAIFPILLIYGNGITNTVDSFIV
CHHHHHHHHCCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
HQLHMNSPNRALLAFILIAGLISVMLMNEKIMLKITEFLVYPLVCILLALSLYLIPEWNT
HHHHCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
SMLTEFPSTQALFSTLWITIPVLVFSFNHSPAISSFAQSQQREYGDLTNTETHTNRTLKI
HHHHHCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHH
TSSILLVFVMFFVFSCVLSLTPAELAQAKTQNISILSFLANKFDNPYISYLGPFVAFLAI
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHHHH
TSSFFGHYLGAKEGLEGLIIKMSGKKEIKCQKLNYFTALFFLLTLWIVAIINPSILGLIE
HHHHHHHHHCHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHH
SFGGPIIAAILFIMPMYAIRKIPAMQRYQGRFSNLFVTIMGMFAISAVVYGLF
HHCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; D-serine [Periplasm] [C]

Specific reaction: Proton [Periplasm] + D-serine [Periplasm] = Proton [Cytoplasm] + D-serine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]