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The map label for this gene is sdaA [H]

Identifier: 15601901

GI number: 15601901

Start: 35843

End: 37210

Strand: Reverse

Name: sdaA [H]

Synonym: PM0036

Alternate gene names: 15601901

Gene position: 37210-35843 (Counterclockwise)

Preceding gene: 15601902

Following gene: 15601898

Centisome position: 1.65

GC content: 43.13

Gene sequence:

>1368_bases
ATGATTAGTGTTTTTGATATGTTTAAAATTGGTATCGGTCCCTCGAGTTCCCATACTGTCGGTCCCATGAAAGCGGGCAA
ACAATTTATTGATGATCTTGTGAGTCGTCATCAGCTAGCACAAGTGAGTAAACTGCGTGTGGAGGTGTACGGTTCACTTT
CCATGACAGGACGTGGACATAATACCGACATTGCCATTATTATGGGATTAGCCGGCTATTTACCCCATGATGTGGATATC
GAGTTGATCCCTCAATTTATTTCTACCCTAAAACAGACTGCCCGTTTGCCCATTGCGCAAAATACGAAAGAGGTCACCTT
TAATTTTAATGATGACTTAATCTTTCATCAAACCTTCCTCCCACGACATGAAAATGGGATGACCATTACCGCACTAGCAC
AAGATGATACGGAACTTTATCAGCAAACCTACTACTCTATCGGAGGTGGGTTTATTGTGGATGAAGAACATTTTGAACAT
GCTATGCATACTGAAATCAGTGTGCCATTTCCTTACCAAAATGCAGCAGATATGCTAAAACACTGCGATGACAATGGTCT
CCCGTTGTCTAGTGTTGTGATGAAAAATGAAACCGCATTACATGGAAAAACCGCATTAAGCCAACATTTACAACAGGTCT
GGCAAACCATGAAAGCCTGTATCCAACACGGTATCAATACAGAAGGTTTATTACCGGGTCCATTAAAAGTACCTCGTCGC
GCGGCAAGCTTATATCGAATGTTACAAGCGAATAGTAGCTTATCCAATGATCCAATGAGCATTGTGGATTGGGTGAATAT
GTATGCGCTTGCTGTCAATGAAGAAAATGCTGCAGGCGGACGTGTGGTAACTGCGCCAACCAACGGAGCTTGTGGTATTG
TGCCTGCTGTATTTGCTTATTACGAACAATTCATCGCAGATAGCATACCTGACATCATCGAACGTTATTTATTAACTTGT
AGCTTTATTGGTTCACTGTACAAAATGAATGCGTCGATTTCAGGTGCTGAAGTAGGCTGCCAAGGCGAAGTTGGTGTAGC
TTGTTCTATGGCGGCGGCTGGCTTGACTGAAATTCTGGGTGGTAGTCCTGAACAAGTATGTATTGCGGCAGAAATTGCCA
TGGAACATAATCTTGGTCTGACTTGTGATCCAGTGGGAGGACAGGTACAGGTCCCTTGTATTGAACGTAACGCTATCGCC
GCGGTTAAAGCCATTAATGCCAGTCGAATGGCATTGCGTCGAACAACCAGTCCACGAGTCACTTTAGACAAGGTCATTGA
AACTATGTATGAAACAGGCAAAGATATGAATGCTAAATACCGTGAAACCTCGCAGGGTGGATTGGCTATTAAAGTAGTCT
GTTCATAA

Upstream 100 bases:

>100_bases
GGGTATGTTCGCCATCTCAGCGGTTGTTTATGGCTTATTTTAATTCGGCAAAATCCGTGTAGAATAGCCTCCCTTTTACG
CTAAAGAAAAGTAGAAATGT

Downstream 100 bases:

>100_bases
CTCATTTAAAAGGGCTTATTACAAGCCCTTTTTTATCTAATAACGATAATGCCCAATCATTTTATATTTAAATAAAATAT
CTTCTTCCTGCGTACCCGCA

Product: hypothetical protein

Products: NA

Alternate protein names: SDH; L-serine deaminase; L-SD [H]

Number of amino acids: Translated: 455; Mature: 455

Protein sequence:

>455_residues
MISVFDMFKIGIGPSSSHTVGPMKAGKQFIDDLVSRHQLAQVSKLRVEVYGSLSMTGRGHNTDIAIIMGLAGYLPHDVDI
ELIPQFISTLKQTARLPIAQNTKEVTFNFNDDLIFHQTFLPRHENGMTITALAQDDTELYQQTYYSIGGGFIVDEEHFEH
AMHTEISVPFPYQNAADMLKHCDDNGLPLSSVVMKNETALHGKTALSQHLQQVWQTMKACIQHGINTEGLLPGPLKVPRR
AASLYRMLQANSSLSNDPMSIVDWVNMYALAVNEENAAGGRVVTAPTNGACGIVPAVFAYYEQFIADSIPDIIERYLLTC
SFIGSLYKMNASISGAEVGCQGEVGVACSMAAAGLTEILGGSPEQVCIAAEIAMEHNLGLTCDPVGGQVQVPCIERNAIA
AVKAINASRMALRRTTSPRVTLDKVIETMYETGKDMNAKYRETSQGGLAIKVVCS

Sequences:

>Translated_455_residues
MISVFDMFKIGIGPSSSHTVGPMKAGKQFIDDLVSRHQLAQVSKLRVEVYGSLSMTGRGHNTDIAIIMGLAGYLPHDVDI
ELIPQFISTLKQTARLPIAQNTKEVTFNFNDDLIFHQTFLPRHENGMTITALAQDDTELYQQTYYSIGGGFIVDEEHFEH
AMHTEISVPFPYQNAADMLKHCDDNGLPLSSVVMKNETALHGKTALSQHLQQVWQTMKACIQHGINTEGLLPGPLKVPRR
AASLYRMLQANSSLSNDPMSIVDWVNMYALAVNEENAAGGRVVTAPTNGACGIVPAVFAYYEQFIADSIPDIIERYLLTC
SFIGSLYKMNASISGAEVGCQGEVGVACSMAAAGLTEILGGSPEQVCIAAEIAMEHNLGLTCDPVGGQVQVPCIERNAIA
AVKAINASRMALRRTTSPRVTLDKVIETMYETGKDMNAKYRETSQGGLAIKVVCS
>Mature_455_residues
MISVFDMFKIGIGPSSSHTVGPMKAGKQFIDDLVSRHQLAQVSKLRVEVYGSLSMTGRGHNTDIAIIMGLAGYLPHDVDI
ELIPQFISTLKQTARLPIAQNTKEVTFNFNDDLIFHQTFLPRHENGMTITALAQDDTELYQQTYYSIGGGFIVDEEHFEH
AMHTEISVPFPYQNAADMLKHCDDNGLPLSSVVMKNETALHGKTALSQHLQQVWQTMKACIQHGINTEGLLPGPLKVPRR
AASLYRMLQANSSLSNDPMSIVDWVNMYALAVNEENAAGGRVVTAPTNGACGIVPAVFAYYEQFIADSIPDIIERYLLTC
SFIGSLYKMNASISGAEVGCQGEVGVACSMAAAGLTEILGGSPEQVCIAAEIAMEHNLGLTCDPVGGQVQVPCIERNAIA
AVKAINASRMALRRTTSPRVTLDKVIETMYETGKDMNAKYRETSQGGLAIKVVCS

Specific function: Deaminates Also Threonine, Particularly When It Is Present In High Concentration. [C]

COG id: COG1760

COG function: function code E; L-serine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-sulfur dependent L-serine dehydratase family [H]

Homologues:

Organism=Escherichia coli, GI1788116, Length=454, Percent_Identity=68.942731277533, Blast_Score=665, Evalue=0.0,
Organism=Escherichia coli, GI1789161, Length=453, Percent_Identity=69.757174392936, Blast_Score=658, Evalue=0.0,
Organism=Escherichia coli, GI48994925, Length=454, Percent_Identity=65.4185022026432, Blast_Score=620, Evalue=1e-179,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004644
- InterPro:   IPR005130
- InterPro:   IPR005131 [H]

Pfam domain/function: PF03313 SDH_alpha; PF03315 SDH_beta [H]

EC number: =4.3.1.17 [H]

Molecular weight: Translated: 49420; Mature: 49420

Theoretical pI: Translated: 5.70; Mature: 5.70

Prosite motif: PS00133 CARBOXYPEPT_ZN_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISVFDMFKIGIGPSSSHTVGPMKAGKQFIDDLVSRHQLAQVSKLRVEVYGSLSMTGRGH
CCCCEEEHEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEEEECCCCC
NTDIAIIMGLAGYLPHDVDIELIPQFISTLKQTARLPIAQNTKEVTFNFNDDLIFHQTFL
CCCEEEEEEHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCEEEEEEEC
PRHENGMTITALAQDDTELYQQTYYSIGGGFIVDEEHFEHAMHTEISVPFPYQNAADMLK
CCCCCCCEEEEEECCHHHHHHHHHHHCCCCEEECHHHHHHHHHCEEECCCCCCCHHHHHH
HCDDNGLPLSSVVMKNETALHGKTALSQHLQQVWQTMKACIQHGINTEGLLPGPLKVPRR
HCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHH
AASLYRMLQANSSLSNDPMSIVDWVNMYALAVNEENAAGGRVVTAPTNGACGIVPAVFAY
HHHHHHHHHHCCCCCCCCHHHHHHHHHEEEEECCCCCCCCEEEECCCCCCCHHHHHHHHH
YEQFIADSIPDIIERYLLTCSFIGSLYKMNASISGAEVGCQGEVGVACSMAAAGLTEILG
HHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHC
GSPEQVCIAAEIAMEHNLGLTCDPVGGQVQVPCIERNAIAAVKAINASRMALRRTTSPRV
CCCCCEEEEEEHHHHCCCCEEECCCCCEEEEEEECCCHHHHHHHHCHHHHHHHCCCCCCE
TLDKVIETMYETGKDMNAKYRETSQGGLAIKVVCS
EHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEEEC
>Mature Secondary Structure
MISVFDMFKIGIGPSSSHTVGPMKAGKQFIDDLVSRHQLAQVSKLRVEVYGSLSMTGRGH
CCCCEEEHEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEEEECCCCC
NTDIAIIMGLAGYLPHDVDIELIPQFISTLKQTARLPIAQNTKEVTFNFNDDLIFHQTFL
CCCEEEEEEHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCEEEEEEEC
PRHENGMTITALAQDDTELYQQTYYSIGGGFIVDEEHFEHAMHTEISVPFPYQNAADMLK
CCCCCCCEEEEEECCHHHHHHHHHHHCCCCEEECHHHHHHHHHCEEECCCCCCCHHHHHH
HCDDNGLPLSSVVMKNETALHGKTALSQHLQQVWQTMKACIQHGINTEGLLPGPLKVPRR
HCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHH
AASLYRMLQANSSLSNDPMSIVDWVNMYALAVNEENAAGGRVVTAPTNGACGIVPAVFAY
HHHHHHHHHHCCCCCCCCHHHHHHHHHEEEEECCCCCCCCEEEECCCCCCCHHHHHHHHH
YEQFIADSIPDIIERYLLTCSFIGSLYKMNASISGAEVGCQGEVGVACSMAAAGLTEILG
HHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHC
GSPEQVCIAAEIAMEHNLGLTCDPVGGQVQVPCIERNAIAAVKAINASRMALRRTTSPRV
CCCCCEEEEEEHHHHCCCCEEECCCCCEEEEEEECCCHHHHHHHHCHHHHHHHCCCCCCE
TLDKVIETMYETGKDMNAKYRETSQGGLAIKVVCS
EHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]