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The map label for this gene is dsbE_1

Identifier: 15601876

GI number: 15601876

Start: 10360

End: 10905

Strand: Direct

Name: dsbE_1

Synonym: PM0011

Alternate gene names: 15601876

Gene position: 10360-10905 (Clockwise)

Preceding gene: 15601875

Following gene: 15601877

Centisome position: 0.46

GC content: 37.18

Gene sequence:

>546_bases
ATGAACAAAAAATTGTATTTTCCCTTAATTTTATTCTTAATTTTAGTTTTTGCGTTTGCTGTTCAGCTCCTGCGTAACGC
GCAAGGTGATGATCCTAAAGCATTAGAATCGGCCTTAATTGGTAAACCTGTTCCGCTGAGAACATTACAGGACTTGTTTG
AAGAGAAGCAATATGGCATTGAAATTTTTCAGCAAGGTAAACCGATTTTATTAAATGTTTGGGCAACCTGGTGTCCAACC
TGCTATGCCGAGCATCAATATTTAAATAAGTTGGCACAACAAGGTGTGACAATTATTGGTATTGATTATAAGGATAAGTC
AGCACAGGCGATAAAATGGCTAAAAGATCTGGGTAATCCTTATCAGATTGTTTTAAAAGATGAAAAAGGCTCAAATGGTT
TAGATTTAGGGGTCTATGGCGCACCAGAAACCTTTGTCATTGACGGACAAGGTATCATTCATTATCGTCATGCGGGGGAT
TTAAATCAGAAAGTGTGGGATGAGAAAATCCAGCCGATTTATCAAAAATTGGTGGAGAGAAAATAA

Upstream 100 bases:

>100_bases
GCTGGATTTGGTTCGGTGGTGTCTTTATGGCATTAGGTGGATTACTCTGTATGTTTGATCGTCGTTATCGTTTTGGGAAG
TTATTTACTAAGGGGCAGGC

Downstream 100 bases:

>100_bases
TGAAAAAATTGACCGCACTTTTTTTGTTATGTTTGAGTTTCTCGAGCCTTGCTGCGATTGAAGGAGTGCAGTTTTCTTCC
ACGCAACAAGAAAAAGATTA

Product: DsbE

Products: NA

Alternate protein names: Cytochrome c biogenesis protein CcmG

Number of amino acids: Translated: 181; Mature: 181

Protein sequence:

>181_residues
MNKKLYFPLILFLILVFAFAVQLLRNAQGDDPKALESALIGKPVPLRTLQDLFEEKQYGIEIFQQGKPILLNVWATWCPT
CYAEHQYLNKLAQQGVTIIGIDYKDKSAQAIKWLKDLGNPYQIVLKDEKGSNGLDLGVYGAPETFVIDGQGIIHYRHAGD
LNQKVWDEKIQPIYQKLVERK

Sequences:

>Translated_181_residues
MNKKLYFPLILFLILVFAFAVQLLRNAQGDDPKALESALIGKPVPLRTLQDLFEEKQYGIEIFQQGKPILLNVWATWCPT
CYAEHQYLNKLAQQGVTIIGIDYKDKSAQAIKWLKDLGNPYQIVLKDEKGSNGLDLGVYGAPETFVIDGQGIIHYRHAGD
LNQKVWDEKIQPIYQKLVERK
>Mature_181_residues
MNKKLYFPLILFLILVFAFAVQLLRNAQGDDPKALESALIGKPVPLRTLQDLFEEKQYGIEIFQQGKPILLNVWATWCPT
CYAEHQYLNKLAQQGVTIIGIDYKDKSAQAIKWLKDLGNPYQIVLKDEKGSNGLDLGVYGAPETFVIDGQGIIHYRHAGD
LNQKVWDEKIQPIYQKLVERK

Specific function: Involved in disulfide bond formation. Catalyzes a late, reductive step in the assembly of periplasmic c-type cytochromes, probably the reduction of disulfide bonds of the apocytochrome c to allow covalent linkage with the heme. Possible subunit of a heme

COG id: COG0526

COG function: function code OC; Thiol-disulfide isomerase and thioredoxins

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein; Periplasmic side

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain

Homologues:

Organism=Escherichia coli, GI1788523, Length=175, Percent_Identity=61.7142857142857, Blast_Score=227, Evalue=4e-61,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DSBE_PASMU (Q9CPM6)

Other databases:

- EMBL:   AE004439
- RefSeq:   NP_244948.1
- ProteinModelPortal:   Q9CPM6
- SMR:   Q9CPM6
- GeneID:   1243358
- GenomeReviews:   AE004439_GR
- KEGG:   pmu:PM0011
- NMPDR:   fig|272843.1.peg.11
- HOGENOM:   HBG493509
- OMA:   KWLAEFH
- ProtClustDB:   CLSK869931
- BioCyc:   PMUL272843:PM0011-MONOMER
- InterPro:   IPR004799
- InterPro:   IPR013740
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR012335
- Gene3D:   G3DSA:3.40.30.10
- TIGRFAMs:   TIGR00385

Pfam domain/function: PF08534 Redoxin; SSF52833 Thiordxn-like_fd

EC number: NA

Molecular weight: Translated: 20660; Mature: 20660

Theoretical pI: Translated: 8.18; Mature: 8.18

Prosite motif: PS00194 THIOREDOXIN_1; PS51352 THIOREDOXIN_2

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xb255c5c)-;

Cys/Met content:

1.1 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKKLYFPLILFLILVFAFAVQLLRNAQGDDPKALESALIGKPVPLRTLQDLFEEKQYGI
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
EIFQQGKPILLNVWATWCPTCYAEHQYLNKLAQQGVTIIGIDYKDKSAQAIKWLKDLGNP
HHHHCCCCEEEEEHHHHCCHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHCCCC
YQIVLKDEKGSNGLDLGVYGAPETFVIDGQGIIHYRHAGDLNQKVWDEKIQPIYQKLVER
EEEEEECCCCCCCCEEEEECCCCEEEECCCCEEEEECCCCCHHHHHHHHHHHHHHHHHCC
K
H
>Mature Secondary Structure
MNKKLYFPLILFLILVFAFAVQLLRNAQGDDPKALESALIGKPVPLRTLQDLFEEKQYGI
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
EIFQQGKPILLNVWATWCPTCYAEHQYLNKLAQQGVTIIGIDYKDKSAQAIKWLKDLGNP
HHHHCCCCEEEEEHHHHCCHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHCCCC
YQIVLKDEKGSNGLDLGVYGAPETFVIDGQGIIHYRHAGDLNQKVWDEKIQPIYQKLVER
EEEEEECCCCCCCCEEEEECCCCEEEECCCCEEEEECCCCCHHHHHHHHHHHHHHHHHCC
K
H

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11248100