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The map label for this gene is ccmB [H]

Identifier: 15601871

GI number: 15601871

Start: 6236

End: 6901

Strand: Direct

Name: ccmB [H]

Synonym: PM0006

Alternate gene names: 15601871

Gene position: 6236-6901 (Clockwise)

Preceding gene: 15601870

Following gene: 15601872

Centisome position: 0.28

GC content: 42.79

Gene sequence:

>666_bases
ATGATATTTTTAGCCATTATCAAAAGAGAGTTACAAATTGCGATGCGTAAGCAAGCGGAGATTTTAAATCCGTTATGGTT
CTTTTTGCTAGTGATCACCTTATTTCCCTTAGTGATTGGACCCGATCCGAAATTACTTGCGCGTATTGCACCGGGGATTG
CTTGGGTCGCGGCATTATTATCCGCGTTGTTGTCTTTTGAACGTTTATTCCGAGATGACTTTGTTGATGGTTCTTTAGAA
CAATTAATGTTAACGGCTCAGCCTCTGGCATTAACAGCCTTAGCTAAAGTGATTGCGCATTGGTTACTGACAGGCTTGCC
ACTGATTTTATTATCACCCATTGCGGCGCTGTTACTTTCTTTAGAGGTTGAAATCTGGTGGGCATTGGTGCTGACATTAT
TGATTGGCACCCCTGTGCTCAGTTGCCTTGGCGCGATTGGTGTGGCGTTGACCGTTGGATTACGTAAAGGCGGCGTGTTA
TTAAGTTTATTAGTTGTGCCGTTATTTATTCCCGTTTTAATTTTTTCGGCTTCTGTGTTAGAAGCTGCCAGTTTAAGCCT
ACCTTACAGTGGGCAATTAGCCATTTTAGGCGCTATTTTAGCCGGCTCTGTAACATTATCGCCGTTTGCTATTGCGGCTG
CATTACGAATTAGCTTAGATCAATAA

Upstream 100 bases:

>100_bases
TACCAGCCACCAAGATGTACAAAGTCGATTATTGAAAAAAGTGCGGTTAGAAAATTATAAATTTACGGAATAGTTCCTTG
CAGAAAGAGCAGCAAATAGC

Downstream 100 bases:

>100_bases
AAGGAAGGCATTATGTGGAAATGGTTACATCCTTATGCAAAATCAGAAACACAGTATCACTTGTGCGGTAAATTTTTACC
CTTAACGGCGTTACTGAGCG

Product: CcmB

Products: NA

Alternate protein names: Cytochrome c-type biogenesis protein CcmB [H]

Number of amino acids: Translated: 221; Mature: 221

Protein sequence:

>221_residues
MIFLAIIKRELQIAMRKQAEILNPLWFFLLVITLFPLVIGPDPKLLARIAPGIAWVAALLSALLSFERLFRDDFVDGSLE
QLMLTAQPLALTALAKVIAHWLLTGLPLILLSPIAALLLSLEVEIWWALVLTLLIGTPVLSCLGAIGVALTVGLRKGGVL
LSLLVVPLFIPVLIFSASVLEAASLSLPYSGQLAILGAILAGSVTLSPFAIAAALRISLDQ

Sequences:

>Translated_221_residues
MIFLAIIKRELQIAMRKQAEILNPLWFFLLVITLFPLVIGPDPKLLARIAPGIAWVAALLSALLSFERLFRDDFVDGSLE
QLMLTAQPLALTALAKVIAHWLLTGLPLILLSPIAALLLSLEVEIWWALVLTLLIGTPVLSCLGAIGVALTVGLRKGGVL
LSLLVVPLFIPVLIFSASVLEAASLSLPYSGQLAILGAILAGSVTLSPFAIAAALRISLDQ
>Mature_221_residues
MIFLAIIKRELQIAMRKQAEILNPLWFFLLVITLFPLVIGPDPKLLARIAPGIAWVAALLSALLSFERLFRDDFVDGSLE
QLMLTAQPLALTALAKVIAHWLLTGLPLILLSPIAALLLSLEVEIWWALVLTLLIGTPVLSCLGAIGVALTVGLRKGGVL
LSLLVVPLFIPVLIFSASVLEAASLSLPYSGQLAILGAILAGSVTLSPFAIAAALRISLDQ

Specific function: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes [H]

COG id: COG2386

COG function: function code O; ABC-type transport system involved in cytochrome c biogenesis, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CcmB/CycW/HelB family [H]

Homologues:

Organism=Escherichia coli, GI1788528, Length=220, Percent_Identity=66.3636363636364, Blast_Score=237, Evalue=4e-64,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003544 [H]

Pfam domain/function: PF03379 CcmB [H]

EC number: NA

Molecular weight: Translated: 23568; Mature: 23568

Theoretical pI: Translated: 7.37; Mature: 7.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIFLAIIKRELQIAMRKQAEILNPLWFFLLVITLFPLVIGPDPKLLARIAPGIAWVAALL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCHHHHHHHHH
SALLSFERLFRDDFVDGSLEQLMLTAQPLALTALAKVIAHWLLTGLPLILLSPIAALLLS
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LEVEIWWALVLTLLIGTPVLSCLGAIGVALTVGLRKGGVLLSLLVVPLFIPVLIFSASVL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
EAASLSLPYSGQLAILGAILAGSVTLSPFAIAAALRISLDQ
HHHHCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MIFLAIIKRELQIAMRKQAEILNPLWFFLLVITLFPLVIGPDPKLLARIAPGIAWVAALL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCHHHHHHHHH
SALLSFERLFRDDFVDGSLEQLMLTAQPLALTALAKVIAHWLLTGLPLILLSPIAALLLS
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LEVEIWWALVLTLLIGTPVLSCLGAIGVALTVGLRKGGVLLSLLVVPLFIPVLIFSASVL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
EAASLSLPYSGQLAILGAILAGSVTLSPFAIAAALRISLDQ
HHHHCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]