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Identifier: 15835518

GI number: 15835518

Start: 1046717

End: 1047085

Strand: Reverse

Name: Not Available

Synonym: TC0904

Alternate gene names: 15835518

Gene position: 1047085-1046717 (Counterclockwise)

Preceding gene: 15835519

Following gene: 15835517

Centisome position: 97.59

GC content: 41.19

Gene sequence:

>369_bases
TTGTATCGGTTAGACGTAACGAACTTTCGTGTTTGGGTATCTATAGGGGTCTCAGAGCAGGAACGCTATCACAAGCAACC
AATTCTTGTTTCTGTATCACTCGTTTTTAGAGAAGAGCCCAAGGTGTGTTCTACAGACGAGATTTCTGATGGTATTTGTT
ACGCTGCACTTGTTTCTCTTATTGAGCAGACAGCAGCAAATCATCCCTGCGCTTTACTTGAGCGTTTAGCTAAGGTCTTG
CTGGAAAAATTAGAAGAGAGTTTAGCACAATTTGTGTGTAAAATTGACCTGCGAGTAAGTAAAGAGCGTCCTCCAATTCC
CAATTTATTAAGTCCAGTGAGTTTTAGCATAAGTAAAGAGGTTCCGTGA

Upstream 100 bases:

>100_bases
CAGCTACGAGCATTCTTGGATTTATTGGAAGAAGAGAAGACTGGTTCGGGCAAGATTAAGAGTTATAAGAATTAAGGATT
CCTTTTCATAAGGAGTATGC

Downstream 100 bases:

>100_bases
CTACTTGGAATTTTGTGTGTTTAGGGTTGGGTTCGAATTTGGGGAATCGCCATGAGTACATTAAACGTGCTTATGAGAGT
TTAAAGAAGGCAGGGATAAG

Product: DhnA family protein

Products: NA

Alternate protein names: DHNA

Number of amino acids: Translated: 122; Mature: 122

Protein sequence:

>122_residues
MYRLDVTNFRVWVSIGVSEQERYHKQPILVSVSLVFREEPKVCSTDEISDGICYAALVSLIEQTAANHPCALLERLAKVL
LEKLEESLAQFVCKIDLRVSKERPPIPNLLSPVSFSISKEVP

Sequences:

>Translated_122_residues
MYRLDVTNFRVWVSIGVSEQERYHKQPILVSVSLVFREEPKVCSTDEISDGICYAALVSLIEQTAANHPCALLERLAKVL
LEKLEESLAQFVCKIDLRVSKERPPIPNLLSPVSFSISKEVP
>Mature_122_residues
MYRLDVTNFRVWVSIGVSEQERYHKQPILVSVSLVFREEPKVCSTDEISDGICYAALVSLIEQTAANHPCALLERLAKVL
LEKLEESLAQFVCKIDLRVSKERPPIPNLLSPVSFSISKEVP

Specific function: Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin

COG id: COG1539

COG function: function code H; Dihydroneopterin aldolase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHNA family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FOLB_CHLMU (Q9PJC6)

Other databases:

- EMBL:   AE002160
- PIR:   H81652
- RefSeq:   NP_297277.1
- ProteinModelPortal:   Q9PJC6
- SMR:   Q9PJC6
- GeneID:   1246273
- GenomeReviews:   AE002160_GR
- KEGG:   cmu:TC0904
- TIGR:   TC_0904
- HOGENOM:   HBG402778
- OMA:   KERPPVP
- ProtClustDB:   CLSK871488
- BioCyc:   CMUR243161:TC_0904-MONOMER
- BRENDA:   4.1.2.25
- InterPro:   IPR006156
- InterPro:   IPR006157
- PANTHER:   PTHR20941:SF3
- SMART:   SM00905
- TIGRFAMs:   TIGR00525
- TIGRFAMs:   TIGR00526

Pfam domain/function: PF02152 FolB

EC number: =4.1.2.25

Molecular weight: Translated: 13770; Mature: 13770

Theoretical pI: Translated: 5.76; Mature: 5.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.3 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
3.3 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYRLDVTNFRVWVSIGVSEQERYHKQPILVSVSLVFREEPKVCSTDEISDGICYAALVSL
CEEECCCCEEEEEEECCCHHHHHCCCCEEEEEEEEECCCCCCCCCCCCCCCHHHHHHHHH
IEQTAANHPCALLERLAKVLLEKLEESLAQFVCKIDLRVSKERPPIPNLLSPVSFSISKE
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCEECCCCCCCCCHHCCCCCCCCCC
VP
CC
>Mature Secondary Structure
MYRLDVTNFRVWVSIGVSEQERYHKQPILVSVSLVFREEPKVCSTDEISDGICYAALVSL
CEEECCCCEEEEEEECCCHHHHHCCCCEEEEEEEEECCCCCCCCCCCCCCCHHHHHHHHH
IEQTAANHPCALLERLAKVLLEKLEESLAQFVCKIDLRVSKERPPIPNLLSPVSFSISKE
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCEECCCCCCCCCHHCCCCCCCCCC
VP
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10684935