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Identifier: 15835498

GI number: 15835498

Start: 1027718

End: 1029796

Strand: Reverse

Name: Not Available

Synonym: TC0884

Alternate gene names: 15835498

Gene position: 1029796-1027718 (Counterclockwise)

Preceding gene: 15835506

Following gene: 15835497

Centisome position: 95.98

GC content: 43.43

Gene sequence:

>2079_bases
ATGATTCGGAAATGGAGTGGGATTCTTCTTTGTTTGTTGTTCAGCTGTGCTTCTTGTTTTTGCATAGAAGGAAATAATGA
GAAGGCGACTCCTACTGTAGAGCTTGTGAGTGAAAGTGAACAAGCTGTTAAGGGAGAGGTTGTTCGTATTGGGGCGCTTA
TTGCTATCCCTAAAGGAGAGCATATCTATTGGAAGAATCCAGGAAAGTTTGGGATGCCTTTAAAGATTTCATGGGACCTT
CCTGCAGGATGTGAGTTGCTAGAGGAACATTGGCCCACTCCTGAAATTTTTGAAGAGCCTGGGGATGTTTATTTTGGTTA
TAAACATTCTACTATGGTTGTTGCTGATGTTCGTGTTTCCAAAGAGTTGGAAAGTAGTCAATTAGAGATAAAGTCTCGAG
TAGAGTGGCTTTCTTGCGGAGAGGCTTGTATTCCAGGGTCTTCTGAGAGAACGCTTGTATTACCAGTGGGTCCAGGACCG
TTAATCCATAATGGTAAAGATGCTGCAGCTTTTTCTCGTGTGTTAGCTGCTCAACCCAAGCAGTTGGATAAAGCAATTAC
CATCTCTTATCAGTCAGACGGATTGGATGTTCTTGTAAAGGAAGGGCCATCCCATGGGGAAGTCAAAGCGTGGTTCATTG
CAGAAAATACGCGGGACTTTGCTTATGCTGAGGGAGCCTCAGTAGGTAAAGAGAATGAACGCGTGTGGAGACTTAAGCAT
TTTGAAGGAAACATGCCTAAGGGAGCAAGCTTATCCGGGCTCCTTGTGTTCACGGATGACTCAGGCAGGGTAGTAGCCTC
TTATCAGGTGCGCGATCATCAGGTGCAACAGCTGCCGGCATGGAGTTGGGGATTCCTTTCGATTCTTCTTATGGCTTTTG
TTGGGGGGATCTTATTAAACATCATGCCTTGCGTTTTGCCCCTGATTACCCTGAAGGTATTTAGTTTAATTAAGTCAGCT
TCAGATCATCATTCCTCTTCCGTTGTTAGTGGTGTTTGGTTCACCCTAGGAGCTATTGCAAGCTTTTGGGGATTAGCCAT
TTTTGCTTTGCTATTGAAAGTTTTGGGACAAAATATTGGTTGGGGTTTTCAACTCCAAGAACCTATGTTTGTTGCCGTCT
TGATCATGATTCTCTTCCTATTTGCTTTAAGCTCATTAGGTATGTTTGAGATGGGGATGATTTGTTTAAGCTTAGGGAAA
AAACTTCAAGAAGAAGGAGGAGCTTCTGCAAAGAAACATCAACGGTGGGGGGCTTTTTTCAATGGAGTATTAACAACTTT
CGTTACTACTCCTTGTACAGGCCCGTTTTTAGGCTCCGTTTTGGGGTTAGTCATGGCTGTTTCTTTCATTAAACAGTTAG
CGATTTTTACCGCTATAGGATTAGGAATGGCAAGTCCGTATCTCTTATTTGCCTCTTTCCCACGGATGTTAGCCATTTTA
CCTAAGCCTGGTCCATGGATGGGTACGTTCAAACAATTAACGGGGTTTATGTTACTGGCTACAGCGACCTGGTTGATCTG
GATTTTCGGAGTCGAGACGAGTACAGCAGCAGTGACTATTCTTCTTATAGGACTTTGGTTGGCTGCTATAGGAGCCTGGA
TTTTAGGACGATGGGGAACCCCTGTATCTCCGCGTAAGCAAAGGTTGTGCGCTTCCATAGCCTTTATCTTTTGTATTACG
AGTTCTTTATTTATAGCCTCTGTAGGAGTGCGTTACTTTGATGAAGATGCGTATCCTGTTCAAAGCTCCCATTGGCAAGC
CTTTTCTCCTGAGAAATTAGCTGAATTACGAGCAAAAGGGGTTCCTGTTTTTGTGAATTTTACAGCTAAGTGGTGTTTAA
CTTGTCAGGTTAACAAGCCGCTTCTTTATGCTAATGCACAAGCTTTTGATGCTATGGGCATTGCCACATTAGAAGCTGAT
TGGACGAAAAAAGACCCTCAAATTACGGAAGAGTTAGCCCGCTTGGGACGAGCAAGTGTTCCTTCTTATGTGTACTATCC
TTCTGGGAATAGAGCTCCTGTAGTTTTGCCAGAGAGATTATCGCAAGCGACTTTAGAGGAGATGATTTTTACTAAGTAG

Upstream 100 bases:

>100_bases
TATAGAACCAAGATCCTTTTTGGTATGTAATTTATTGCAAAAACAAAAACAACTCTTCTGTTGTTTTTGTTTTTGCTAAA
CCATAGAGAGTGTTGCGTTT

Downstream 100 bases:

>100_bases
TAGCTCTCTTATAAAAATTTTTCCCTCTAAAAGGGGCTTTTCCTTCATGATTCTTGATTGAGAAAGATTGATTACGAGGA
GAATATGGAGATAACCGATG

Product: thiol:disulfide interchange protein DsbD, putative

Products: NA

Alternate protein names: Protein-disulfide reductase; Disulfide reductase [H]

Number of amino acids: Translated: 692; Mature: 692

Protein sequence:

>692_residues
MIRKWSGILLCLLFSCASCFCIEGNNEKATPTVELVSESEQAVKGEVVRIGALIAIPKGEHIYWKNPGKFGMPLKISWDL
PAGCELLEEHWPTPEIFEEPGDVYFGYKHSTMVVADVRVSKELESSQLEIKSRVEWLSCGEACIPGSSERTLVLPVGPGP
LIHNGKDAAAFSRVLAAQPKQLDKAITISYQSDGLDVLVKEGPSHGEVKAWFIAENTRDFAYAEGASVGKENERVWRLKH
FEGNMPKGASLSGLLVFTDDSGRVVASYQVRDHQVQQLPAWSWGFLSILLMAFVGGILLNIMPCVLPLITLKVFSLIKSA
SDHHSSSVVSGVWFTLGAIASFWGLAIFALLLKVLGQNIGWGFQLQEPMFVAVLIMILFLFALSSLGMFEMGMICLSLGK
KLQEEGGASAKKHQRWGAFFNGVLTTFVTTPCTGPFLGSVLGLVMAVSFIKQLAIFTAIGLGMASPYLLFASFPRMLAIL
PKPGPWMGTFKQLTGFMLLATATWLIWIFGVETSTAAVTILLIGLWLAAIGAWILGRWGTPVSPRKQRLCASIAFIFCIT
SSLFIASVGVRYFDEDAYPVQSSHWQAFSPEKLAELRAKGVPVFVNFTAKWCLTCQVNKPLLYANAQAFDAMGIATLEAD
WTKKDPQITEELARLGRASVPSYVYYPSGNRAPVVLPERLSQATLEEMIFTK

Sequences:

>Translated_692_residues
MIRKWSGILLCLLFSCASCFCIEGNNEKATPTVELVSESEQAVKGEVVRIGALIAIPKGEHIYWKNPGKFGMPLKISWDL
PAGCELLEEHWPTPEIFEEPGDVYFGYKHSTMVVADVRVSKELESSQLEIKSRVEWLSCGEACIPGSSERTLVLPVGPGP
LIHNGKDAAAFSRVLAAQPKQLDKAITISYQSDGLDVLVKEGPSHGEVKAWFIAENTRDFAYAEGASVGKENERVWRLKH
FEGNMPKGASLSGLLVFTDDSGRVVASYQVRDHQVQQLPAWSWGFLSILLMAFVGGILLNIMPCVLPLITLKVFSLIKSA
SDHHSSSVVSGVWFTLGAIASFWGLAIFALLLKVLGQNIGWGFQLQEPMFVAVLIMILFLFALSSLGMFEMGMICLSLGK
KLQEEGGASAKKHQRWGAFFNGVLTTFVTTPCTGPFLGSVLGLVMAVSFIKQLAIFTAIGLGMASPYLLFASFPRMLAIL
PKPGPWMGTFKQLTGFMLLATATWLIWIFGVETSTAAVTILLIGLWLAAIGAWILGRWGTPVSPRKQRLCASIAFIFCIT
SSLFIASVGVRYFDEDAYPVQSSHWQAFSPEKLAELRAKGVPVFVNFTAKWCLTCQVNKPLLYANAQAFDAMGIATLEAD
WTKKDPQITEELARLGRASVPSYVYYPSGNRAPVVLPERLSQATLEEMIFTK
>Mature_692_residues
MIRKWSGILLCLLFSCASCFCIEGNNEKATPTVELVSESEQAVKGEVVRIGALIAIPKGEHIYWKNPGKFGMPLKISWDL
PAGCELLEEHWPTPEIFEEPGDVYFGYKHSTMVVADVRVSKELESSQLEIKSRVEWLSCGEACIPGSSERTLVLPVGPGP
LIHNGKDAAAFSRVLAAQPKQLDKAITISYQSDGLDVLVKEGPSHGEVKAWFIAENTRDFAYAEGASVGKENERVWRLKH
FEGNMPKGASLSGLLVFTDDSGRVVASYQVRDHQVQQLPAWSWGFLSILLMAFVGGILLNIMPCVLPLITLKVFSLIKSA
SDHHSSSVVSGVWFTLGAIASFWGLAIFALLLKVLGQNIGWGFQLQEPMFVAVLIMILFLFALSSLGMFEMGMICLSLGK
KLQEEGGASAKKHQRWGAFFNGVLTTFVTTPCTGPFLGSVLGLVMAVSFIKQLAIFTAIGLGMASPYLLFASFPRMLAIL
PKPGPWMGTFKQLTGFMLLATATWLIWIFGVETSTAAVTILLIGLWLAAIGAWILGRWGTPVSPRKQRLCASIAFIFCIT
SSLFIASVGVRYFDEDAYPVQSSHWQAFSPEKLAELRAKGVPVFVNFTAKWCLTCQVNKPLLYANAQAFDAMGIATLEAD
WTKKDPQITEELARLGRASVPSYVYYPSGNRAPVVLPERLSQATLEEMIFTK

Specific function: Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a

COG id: COG4232

COG function: function code OC; Thiol:disulfide interchange protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1790578, Length=395, Percent_Identity=26.0759493670886, Blast_Score=73, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003834
- InterPro:   IPR022910
- InterPro:   IPR005746
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR013766
- InterPro:   IPR012335 [H]

Pfam domain/function: PF02683 DsbD; PF00085 Thioredoxin [H]

EC number: =1.8.1.8 [H]

Molecular weight: Translated: 75876; Mature: 75876

Theoretical pI: Translated: 7.62; Mature: 7.62

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS00194 THIOREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRKWSGILLCLLFSCASCFCIEGNNEKATPTVELVSESEQAVKGEVVRIGALIAIPKGE
CCCCHHHHHHHHHHHHHCEEEEECCCCCCCCHHHHHHCCHHHHCCCEEEEEEEEEECCCC
HIYWKNPGKFGMPLKISWDLPAGCELLEEHWPTPEIFEEPGDVYFGYKHSTMVVADVRVS
EEEECCCCCCCCCEEEECCCCCHHHHHHHHCCCCHHHCCCCCEEEEECCCEEEEEEEHHH
KELESSQLEIKSRVEWLSCGEACIPGSSERTLVLPVGPGPLIHNGKDAAAFSRVLAAQPK
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHCCCH
QLDKAITISYQSDGLDVLVKEGPSHGEVKAWFIAENTRDFAYAEGASVGKENERVWRLKH
HCCCEEEEEECCCCCEEEEECCCCCCCEEEEEEECCCCCCEECCCCCCCCCCCCEEEEEE
FEGNMPKGASLSGLLVFTDDSGRVVASYQVRDHQVQQLPAWSWGFLSILLMAFVGGILLN
CCCCCCCCCCCCEEEEEECCCCCEEEEEECCHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
IMPCVLPLITLKVFSLIKSASDHHSSSVVSGVWFTLGAIASFWGLAIFALLLKVLGQNIG
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
WGFQLQEPMFVAVLIMILFLFALSSLGMFEMGMICLSLGKKLQEEGGASAKKHQRWGAFF
CCEEECCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
NGVLTTFVTTPCTGPFLGSVLGLVMAVSFIKQLAIFTAIGLGMASPYLLFASFPRMLAIL
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHEEC
PKPGPWMGTFKQLTGFMLLATATWLIWIFGVETSTAAVTILLIGLWLAAIGAWILGRWGT
CCCCCCCHHHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCC
PVSPRKQRLCASIAFIFCITSSLFIASVGVRYFDEDAYPVQSSHWQAFSPEKLAELRAKG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHCC
VPVFVNFTAKWCLTCQVNKPLLYANAQAFDAMGIATLEADWTKKDPQITEELARLGRASV
CCEEEEEEEEEEEEEECCCCEEEECCCHHHCCCEEEEECCCCCCCHHHHHHHHHCCCCCC
PSYVYYPSGNRAPVVLPERLSQATLEEMIFTK
CCEEEECCCCCCCEECHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MIRKWSGILLCLLFSCASCFCIEGNNEKATPTVELVSESEQAVKGEVVRIGALIAIPKGE
CCCCHHHHHHHHHHHHHCEEEEECCCCCCCCHHHHHHCCHHHHCCCEEEEEEEEEECCCC
HIYWKNPGKFGMPLKISWDLPAGCELLEEHWPTPEIFEEPGDVYFGYKHSTMVVADVRVS
EEEECCCCCCCCCEEEECCCCCHHHHHHHHCCCCHHHCCCCCEEEEECCCEEEEEEEHHH
KELESSQLEIKSRVEWLSCGEACIPGSSERTLVLPVGPGPLIHNGKDAAAFSRVLAAQPK
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHCCCH
QLDKAITISYQSDGLDVLVKEGPSHGEVKAWFIAENTRDFAYAEGASVGKENERVWRLKH
HCCCEEEEEECCCCCEEEEECCCCCCCEEEEEEECCCCCCEECCCCCCCCCCCCEEEEEE
FEGNMPKGASLSGLLVFTDDSGRVVASYQVRDHQVQQLPAWSWGFLSILLMAFVGGILLN
CCCCCCCCCCCCEEEEEECCCCCEEEEEECCHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
IMPCVLPLITLKVFSLIKSASDHHSSSVVSGVWFTLGAIASFWGLAIFALLLKVLGQNIG
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
WGFQLQEPMFVAVLIMILFLFALSSLGMFEMGMICLSLGKKLQEEGGASAKKHQRWGAFF
CCEEECCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
NGVLTTFVTTPCTGPFLGSVLGLVMAVSFIKQLAIFTAIGLGMASPYLLFASFPRMLAIL
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHEEC
PKPGPWMGTFKQLTGFMLLATATWLIWIFGVETSTAAVTILLIGLWLAAIGAWILGRWGT
CCCCCCCHHHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCC
PVSPRKQRLCASIAFIFCITSSLFIASVGVRYFDEDAYPVQSSHWQAFSPEKLAELRAKG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHCC
VPVFVNFTAKWCLTCQVNKPLLYANAQAFDAMGIATLEADWTKKDPQITEELARLGRASV
CCEEEEEEEEEEEEEECCCCEEEECCCHHHCCCEEEEECCCCCCCHHHHHHHHHCCCCCC
PSYVYYPSGNRAPVVLPERLSQATLEEMIFTK
CCEEEECCCCCCCEECHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA