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The map label for this gene is sdhB

Identifier: 15835494

GI number: 15835494

Start: 1023147

End: 1023944

Strand: Reverse

Name: sdhB

Synonym: TC0880

Alternate gene names: 15835494

Gene position: 1023944-1023147 (Counterclockwise)

Preceding gene: 15835495

Following gene: 15835493

Centisome position: 95.43

GC content: 42.48

Gene sequence:

>798_bases
GTGCAAGAAACGTTTATATTGAATATATACAGAGGCGTTCCTGGAAAACAGTATTGGGAAAGTTTTGAGTTGGAGTTGCA
TCCCGGAGAGAATGTAATTAGTGCCCTTATGGAGATTGAAAAAAATCCCATAAATACTCAAGGGGAGCGGGTGGATCCTG
TAGTTTGGGAACAGGCGTGTTTAGAAGAGGTCTGTGGTTCTTGCGCGATGCTAGTGAATGGGGTGCCCAGACAAGCTTGT
ACGGTATTAATTCATGAACATATGGATGCCAAACGAGAGATCAAATTGGCGCCTCTTTCCAAGTTCCCATTAGTTCGTGA
TTTGATTGTAGATCGTTCTGTGATGTTCAAAAATTTAGAAGAGATCCAGGGATGGATTTCTGCTGATAAATGTGGCGAAG
GACCTGGTCCACAAGTCTCTCAAGAAGAGCAGGCTTTAATGTATTCTTTATCGATGTGTATGACCTGTGGATGTTGCACA
GAGGCTTGTCCCCAAGTTAATGAGAAAAGCGATTTTATGGGACCTGCAGCCATTGCTCAGGCTCGTTATTTTAACTCCTA
TCCTGGAGAGAAGCGACGAGAGAGTCGATTACGAGCTCTTATGGGGAATCGAGGAATAGAAGGGTGTGGTCAAGCACATA
ATTGCGTGCGTGTCTGCCCAAAAAAATTGCCTTTAACAGAAAGTATCTCAGCTATGGGATATGAGGTTTCTCGTTTTTCT
CTGCGGGCACTATTTACTGCTTTATTTAAGAAGAAAAAAGAAAAAGAACCAAAAGATTCTATAGATCCTGAGGTGTAA

Upstream 100 bases:

>100_bases
TGTGAACCCAGAATTACGAGATTATACACAACGGGGAGAGAAAGACGTAGTGTTAGAGAATATTCCAACGAATATTCATT
TCCCTATATAGGAGGCTATT

Downstream 100 bases:

>100_bases
GTTTCGGAGATTGCATCGCAATTTTGTTCCATGGTAAAGGATGAGAAAAAACTCCTTTCTTTGCCATGTCTCGGTTGGAC
GTCTTTGTATTCGATTCCTT

Product: succinate dehydrogenase iron-sulfur subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 265; Mature: 265

Protein sequence:

>265_residues
MQETFILNIYRGVPGKQYWESFELELHPGENVISALMEIEKNPINTQGERVDPVVWEQACLEEVCGSCAMLVNGVPRQAC
TVLIHEHMDAKREIKLAPLSKFPLVRDLIVDRSVMFKNLEEIQGWISADKCGEGPGPQVSQEEQALMYSLSMCMTCGCCT
EACPQVNEKSDFMGPAAIAQARYFNSYPGEKRRESRLRALMGNRGIEGCGQAHNCVRVCPKKLPLTESISAMGYEVSRFS
LRALFTALFKKKKEKEPKDSIDPEV

Sequences:

>Translated_265_residues
MQETFILNIYRGVPGKQYWESFELELHPGENVISALMEIEKNPINTQGERVDPVVWEQACLEEVCGSCAMLVNGVPRQAC
TVLIHEHMDAKREIKLAPLSKFPLVRDLIVDRSVMFKNLEEIQGWISADKCGEGPGPQVSQEEQALMYSLSMCMTCGCCT
EACPQVNEKSDFMGPAAIAQARYFNSYPGEKRRESRLRALMGNRGIEGCGQAHNCVRVCPKKLPLTESISAMGYEVSRFS
LRALFTALFKKKKEKEPKDSIDPEV
>Mature_265_residues
MQETFILNIYRGVPGKQYWESFELELHPGENVISALMEIEKNPINTQGERVDPVVWEQACLEEVCGSCAMLVNGVPRQAC
TVLIHEHMDAKREIKLAPLSKFPLVRDLIVDRSVMFKNLEEIQGWISADKCGEGPGPQVSQEEQALMYSLSMCMTCGCCT
EACPQVNEKSDFMGPAAIAQARYFNSYPGEKRRESRLRALMGNRGIEGCGQAHNCVRVCPKKLPLTESISAMGYEVSRFS
LRALFTALFKKKKEKEPKDSIDPEV

Specific function: Two Distinct, Membrane-Bound, FAD-Containing Enzymes Are Responsible For The Catalysis Of Fumarate And Succinate Interconversion; The Fumarate Reductase Is Used In Anaerobic Growth, And The Succinate Dehydrogenase Is Used In Aerobic Growth. [C]

COG id: COG0479

COG function: function code C; Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 4Fe-4S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI115387094, Length=230, Percent_Identity=29.5652173913043, Blast_Score=94, Evalue=2e-19,
Organism=Escherichia coli, GI1790596, Length=189, Percent_Identity=31.7460317460317, Blast_Score=108, Evalue=3e-25,
Organism=Escherichia coli, GI1786943, Length=233, Percent_Identity=28.3261802575107, Blast_Score=86, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17533915, Length=244, Percent_Identity=27.4590163934426, Blast_Score=89, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6322987, Length=225, Percent_Identity=26.2222222222222, Blast_Score=87, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24643156, Length=260, Percent_Identity=28.0769230769231, Blast_Score=96, Evalue=3e-20,
Organism=Drosophila melanogaster, GI17137106, Length=226, Percent_Identity=29.2035398230088, Blast_Score=95, Evalue=5e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR012675
- InterPro:   IPR001041
- InterPro:   IPR012285
- InterPro:   IPR009051
- InterPro:   IPR004489 [H]

Pfam domain/function: NA

EC number: =1.3.99.1 [H]

Molecular weight: Translated: 29743; Mature: 29743

Theoretical pI: Translated: 5.78; Mature: 5.78

Prosite motif: PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.9 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
9.1 %Cys+Met (Translated Protein)
4.9 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
9.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQETFILNIYRGVPGKQYWESFELELHPGENVISALMEIEKNPINTQGERVDPVVWEQAC
CCCEEEEEEECCCCCHHHHHCCCEEECCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHH
LEEVCGSCAMLVNGVPRQACTVLIHEHMDAKREIKLAPLSKFPLVRDLIVDRSVMFKNLE
HHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHCEEECCCCCCHHHHHHHHHHHHHHHHHH
EIQGWISADKCGEGPGPQVSQEEQALMYSLSMCMTCGCCTEACPQVNEKSDFMGPAAIAQ
HHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHCCCHHHHHH
ARYFNSYPGEKRRESRLRALMGNRGIEGCGQAHNCVRVCPKKLPLTESISAMGYEVSRFS
HHHHCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHCHHHHHHH
LRALFTALFKKKKEKEPKDSIDPEV
HHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MQETFILNIYRGVPGKQYWESFELELHPGENVISALMEIEKNPINTQGERVDPVVWEQAC
CCCEEEEEEECCCCCHHHHHCCCEEECCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHH
LEEVCGSCAMLVNGVPRQACTVLIHEHMDAKREIKLAPLSKFPLVRDLIVDRSVMFKNLE
HHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHCEEECCCCCCHHHHHHHHHHHHHHHHHH
EIQGWISADKCGEGPGPQVSQEEQALMYSLSMCMTCGCCTEACPQVNEKSDFMGPAAIAQ
HHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHCCCHHHHHH
ARYFNSYPGEKRRESRLRALMGNRGIEGCGQAHNCVRVCPKKLPLTESISAMGYEVSRFS
HHHHCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHCHHHHHHH
LRALFTALFKKKKEKEPKDSIDPEV
HHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3027051; 8969504; 9384377; 3114423 [H]