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Identifier: 15835455

GI number: 15835455

Start: 975016

End: 976122

Strand: Direct

Name: Not Available

Synonym: TC0841

Alternate gene names: 15835455

Gene position: 975016-976122 (Clockwise)

Preceding gene: 15835454

Following gene: 15835456

Centisome position: 90.87

GC content: 42.01

Gene sequence:

>1107_bases
ATGATCCCCTTTCGCCTTCACCATCTTTACACCTTACTAGATAGTTTGTTCTCTTCTCCTATTGGAGAAAGCAACAGGGT
GGCAGCATACTTCAAAGAACACCCCGCCCTTGGCTCTAAAGATCGTCAATGGATAAACTCTCGTATTTTCACTATTCTAC
GTCACCGACGTTTACTAGAAACCTTGATTCTAGAAGAGGGTAAAGAGATCTCTTCACAAACATTAGTAGAAAAAGTAGAG
GAAGGCGTAACTGAAAATATTGAACACTTTCAACACCTCCCTTGGGCCGTCCGCTACTCTGTATCTGATGATTTAGCAGA
ATGTTTGTCCGCGGATTACGGTGAAGAAGAAGCGATCCGCTTAGCTAAAATTTTTTTGGAAGAAGCGCCCTGTTCCATTC
GCGTAAATACAAGACGTATTTCCGTAGATAAACTTCAAGAAGTCTTGCCTTTCTCTAGCCAAAGAGGCGCAGCCCCTTCC
TCTTTACGTTTTGACAAGCGCTATCCTTTACAACATACGCGAGCATTCCGTAGAGGACTTTTTGAAATTCAAGACGAATC
TTCTCAAATTATTACCAATGCCATTCTTGTTAAAGATTCCGATACTGTTTTAGATTTTTGTGCTGGAGCTGGAGGGAAGA
GCCTGATTTTTGCCCAGAGAGCTCAACACGTAACTCTGCATGATAGCCGACCACAAGCATTAGAAGAAGCTCGCCAACGC
CTATCTCGTTCGGGAATAAAAAATTTTACTATTGCTTCCCTTCCTCTTAAACAACATGGTTTCTCTTTAGTTGTGGTAGA
TGCTCCTTGTACAGGAAGCGGAGTCTTCCGACGCCATCCAGAAAAAAAATTACTCTTCTCAAAACAACTCCTTAAGAATA
ATTCCGTTGCTCAGGGAAAAATTTTAAAACAAGCGCAAACCTACGTAGCTCCTCGCGGACGATTAGTTTATATCACCTGC
TCTCTTCTAAAAGAAGAGAATGAAAAACATACCTTACAAATGGAAGCTCTAGGCTGGAAATGTATTAAAGAAGTAAAGAT
CCCACTCATTTCCCAACAAGGGGATGCCTTTTTCTCCACGCACTTTATCCGAAGACGGGACTTCTAG

Upstream 100 bases:

>100_bases
AAATCCTTGCTCAAGTAATCGAAAAAAGAATTCACTTCCTACTATCAGAACAACAGGTTTCTGAACTTACCAATATATTC
TCTCCCCCAATAGGAGATTC

Downstream 100 bases:

>100_bases
AATCTTGATCTTAAACCATAAGTGTAGGTACTATAGAGCAAGAGCTAGCGGACGTTTCTTCTAATTCATCTTTTTTCTCT
CCAATACCAGTGATTTTTAT

Product: Nol1/Nop2/Sun family protein

Products: NA

Alternate protein names: 16S rRNA m5C967 methyltransferase; rRNA (cytosine-C(5)-)-methyltransferase rsmB [H]

Number of amino acids: Translated: 368; Mature: 368

Protein sequence:

>368_residues
MIPFRLHHLYTLLDSLFSSPIGESNRVAAYFKEHPALGSKDRQWINSRIFTILRHRRLLETLILEEGKEISSQTLVEKVE
EGVTENIEHFQHLPWAVRYSVSDDLAECLSADYGEEEAIRLAKIFLEEAPCSIRVNTRRISVDKLQEVLPFSSQRGAAPS
SLRFDKRYPLQHTRAFRRGLFEIQDESSQIITNAILVKDSDTVLDFCAGAGGKSLIFAQRAQHVTLHDSRPQALEEARQR
LSRSGIKNFTIASLPLKQHGFSLVVVDAPCTGSGVFRRHPEKKLLFSKQLLKNNSVAQGKILKQAQTYVAPRGRLVYITC
SLLKEENEKHTLQMEALGWKCIKEVKIPLISQQGDAFFSTHFIRRRDF

Sequences:

>Translated_368_residues
MIPFRLHHLYTLLDSLFSSPIGESNRVAAYFKEHPALGSKDRQWINSRIFTILRHRRLLETLILEEGKEISSQTLVEKVE
EGVTENIEHFQHLPWAVRYSVSDDLAECLSADYGEEEAIRLAKIFLEEAPCSIRVNTRRISVDKLQEVLPFSSQRGAAPS
SLRFDKRYPLQHTRAFRRGLFEIQDESSQIITNAILVKDSDTVLDFCAGAGGKSLIFAQRAQHVTLHDSRPQALEEARQR
LSRSGIKNFTIASLPLKQHGFSLVVVDAPCTGSGVFRRHPEKKLLFSKQLLKNNSVAQGKILKQAQTYVAPRGRLVYITC
SLLKEENEKHTLQMEALGWKCIKEVKIPLISQQGDAFFSTHFIRRRDF
>Mature_368_residues
MIPFRLHHLYTLLDSLFSSPIGESNRVAAYFKEHPALGSKDRQWINSRIFTILRHRRLLETLILEEGKEISSQTLVEKVE
EGVTENIEHFQHLPWAVRYSVSDDLAECLSADYGEEEAIRLAKIFLEEAPCSIRVNTRRISVDKLQEVLPFSSQRGAAPS
SLRFDKRYPLQHTRAFRRGLFEIQDESSQIITNAILVKDSDTVLDFCAGAGGKSLIFAQRAQHVTLHDSRPQALEEARQR
LSRSGIKNFTIASLPLKQHGFSLVVVDAPCTGSGVFRRHPEKKLLFSKQLLKNNSVAQGKILKQAQTYVAPRGRLVYITC
SLLKEENEKHTLQMEALGWKCIKEVKIPLISQQGDAFFSTHFIRRRDF

Specific function: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA [H]

COG id: COG0144

COG function: function code J; tRNA and rRNA cytosine-C5-methylases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RsmB/NOP family [H]

Homologues:

Organism=Homo sapiens, GI76150625, Length=177, Percent_Identity=28.8135593220339, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI76150623, Length=177, Percent_Identity=28.8135593220339, Blast_Score=71, Evalue=1e-12,
Organism=Escherichia coli, GI2367212, Length=263, Percent_Identity=28.5171102661597, Blast_Score=92, Evalue=8e-20,
Organism=Escherichia coli, GI87081985, Length=224, Percent_Identity=29.0178571428571, Blast_Score=79, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI17536757, Length=219, Percent_Identity=25.5707762557078, Blast_Score=65, Evalue=7e-11,
Organism=Drosophila melanogaster, GI22024126, Length=177, Percent_Identity=29.3785310734463, Blast_Score=66, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001678
- InterPro:   IPR018314
- InterPro:   IPR006027
- InterPro:   IPR004573 [H]

Pfam domain/function: PF01189 Nol1_Nop2_Fmu; PF01029 NusB [H]

EC number: =2.1.1.176 [H]

Molecular weight: Translated: 41967; Mature: 41967

Theoretical pI: Translated: 9.53; Mature: 9.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIPFRLHHLYTLLDSLFSSPIGESNRVAAYFKEHPALGSKDRQWINSRIFTILRHRRLLE
CCCHHHHHHHHHHHHHHCCCCCCCCCEEHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
TLILEEGKEISSQTLVEKVEEGVTENIEHFQHLPWAVRYSVSDDLAECLSADYGEEEAIR
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCHHHHHHHHCCCCCHHHHHH
LAKIFLEEAPCSIRVNTRRISVDKLQEVLPFSSQRGAAPSSLRFDKRYPLQHTRAFRRGL
HHHHHHHCCCCEEEEECEEECHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCC
FEIQDESSQIITNAILVKDSDTVLDFCAGAGGKSLIFAQRAQHVTLHDSRPQALEEARQR
HHCCCCCHHEEEEEEEEECCCHHHHHHCCCCCCEEEEECCCCEEEEECCCCHHHHHHHHH
LSRSGIKNFTIASLPLKQHGFSLVVVDAPCTGSGVFRRHPEKKLLFSKQLLKNNSVAQGK
HHHCCCCCCEEEECCHHHCCCEEEEEECCCCCCCHHHCCCHHHHHHHHHHHCCCCCHHHH
ILKQAQTYVAPRGRLVYITCSLLKEENEKHTLQMEALGWKCIKEVKIPLISQQGDAFFST
HHHHHHHHHCCCCCEEEEEEEHHHCCCCHHEEEHHHHHHHHHHHHCCCEECCCCCHHHHH
HFIRRRDF
HHHHHCCC
>Mature Secondary Structure
MIPFRLHHLYTLLDSLFSSPIGESNRVAAYFKEHPALGSKDRQWINSRIFTILRHRRLLE
CCCHHHHHHHHHHHHHHCCCCCCCCCEEHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
TLILEEGKEISSQTLVEKVEEGVTENIEHFQHLPWAVRYSVSDDLAECLSADYGEEEAIR
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCHHHHHHHHCCCCCHHHHHH
LAKIFLEEAPCSIRVNTRRISVDKLQEVLPFSSQRGAAPSSLRFDKRYPLQHTRAFRRGL
HHHHHHHCCCCEEEEECEEECHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCC
FEIQDESSQIITNAILVKDSDTVLDFCAGAGGKSLIFAQRAQHVTLHDSRPQALEEARQR
HHCCCCCHHEEEEEEEEECCCHHHHHHCCCCCCEEEEECCCCEEEEECCCCHHHHHHHHH
LSRSGIKNFTIASLPLKQHGFSLVVVDAPCTGSGVFRRHPEKKLLFSKQLLKNNSVAQGK
HHHCCCCCCEEEECCHHHCCCEEEEEECCCCCCCHHHCCCHHHHHHHHHHHCCCCCHHHH
ILKQAQTYVAPRGRLVYITCSLLKEENEKHTLQMEALGWKCIKEVKIPLISQQGDAFFST
HHHHHHHHHCCCCCEEEEEEEHHHCCCCHHEEEHHHHHHHHHHHHCCCEECCCCCHHHHH
HFIRRRDF
HHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA