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Identifier: 15835445

GI number: 15835445

Start: 963370

End: 964740

Strand: Direct

Name: Not Available

Synonym: TC0831

Alternate gene names: 15835445

Gene position: 963370-964740 (Clockwise)

Preceding gene: 15835440

Following gene: 15835446

Centisome position: 89.79

GC content: 42.01

Gene sequence:

>1371_bases
ATGAATCTATGGACCAAAATTTTTCAGCCTCCTCGCCACATTAAAGAAATCAGTGATCCGGAGTTGGTTAAAAAGCAATA
TAAATACTGGAGAGTGCGTATCTTTTACAGCATGTTTTTTGGTTACGTGTTCTTCTATTTTACAAGGAAAAGCTTTACCT
TTGCTATGCCAACTCTAATTGCAGATCTTGGATTTGATAAGGCGCAACTAGGGATTATTGGCAGTACACTCTACATTACT
TACGGCATTAGTAAATTTGTAAGCGGTGTGATGTCAGACCAATCCAACCCTCGCTATTTCATGGCGACCGGATTAATTAT
TACTGGCCTCTCTAATATCTTCTTTGGCCTATCGTCTACCGTGCCTTTGTTTGTGCTGTTTTGGGGAATTAATGGTTGGT
TCCAAGGATGGGGCTGGCCTCCTTGTGCACGTCTACTGACTCACTGGTATTCTAAATCAGAAAGAGGAACTTGGTGGAGC
GTCTGGAGTACTTCTCACAATATTGGAGGAGCTTTAATCCCTGTTTTGACTGGAATCGCTATCGATTATGCAGGATGGCG
AGGAGCTATGTTTATCCCAGGAATTATTTGCATTATCATGGGATTTATCTTAATTGACCGTTTGCGAGACACTCCACAAT
CGCTAGGGCTTCCGGCTATAGAAAAGTTTAAAAAAGAAGACCTTTCTCATCCGCATGAGGAAACTACCGCGGATATTTTG
GAAGAGGAGGCCGAAAGAGAGCTTTCCACTAAAGAAATTTTATTTACTTACGTGTTATCAAATAAATGGTTATGGTTCCT
ATCCTTCGCTTCCTTCTTCATTTACGTAGTCCGCATGGCAGTGAACGATTGGAGCGCTCTTTATCTCATTGAGACAAAGA
ATTATTCCACAGTAAAAGCGAATCTCTGCGTATCTTTGTTTGAAATTGGCGGATTATTTGGTATGCTATTAGCGGGCTGG
TTATCCGACACCATTTCTAAAGGAAAGCGAGGGCCAATGAATGTAGTCTTCTCGCTGGGATTACTATTCTCTATCTTGGG
ATTATGGGGAACTCATGATCGTTCTATATGGTGGGCAGATGGAGCATTTCTATTTATCATCGGCTTTTTCCTTTTTGGAC
CACAAATGATGATCGGATTAGCAGCCGCAGAATTATCACATAAAAAAGCCGCTGGAACGGCCAGTGGTTTTACAGGATGG
TTCGCCTATTTCGGAGCTGCTTTTGCTGGATATCCTCTAGGAAAAGTTGCCCAAGATTGGGGATGGCATGGATTCTTTGT
TGCTCTCTTAGCCTGTGCTTTGATTGCACTCCTGTTCTTCTTGCCAACATGGAATGCATCCGAGCAGAGTTTAAGAAAAC
ATAGTCACTAA

Upstream 100 bases:

>100_bases
GCAAAAAACGAGGTCTTAGAAGCTGATACTTCCGTTGTAACACGCGTTTGTATTTTTCTTAAGCTTCTAGAGCAAACACA
CTTGAATCGAGCGAACACCT

Downstream 100 bases:

>100_bases
GTAAAGAGCTGTTTTGACCTGGATTCCTTTACATTGTCACTCTCAATACTCCATTCTGGATGCAACGTGCTCAATCAAAA
AGTTTGTTGCTAAAGCTGTG

Product: GlpT/PgpT/UhpT family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 456; Mature: 456

Protein sequence:

>456_residues
MNLWTKIFQPPRHIKEISDPELVKKQYKYWRVRIFYSMFFGYVFFYFTRKSFTFAMPTLIADLGFDKAQLGIIGSTLYIT
YGISKFVSGVMSDQSNPRYFMATGLIITGLSNIFFGLSSTVPLFVLFWGINGWFQGWGWPPCARLLTHWYSKSERGTWWS
VWSTSHNIGGALIPVLTGIAIDYAGWRGAMFIPGIICIIMGFILIDRLRDTPQSLGLPAIEKFKKEDLSHPHEETTADIL
EEEAERELSTKEILFTYVLSNKWLWFLSFASFFIYVVRMAVNDWSALYLIETKNYSTVKANLCVSLFEIGGLFGMLLAGW
LSDTISKGKRGPMNVVFSLGLLFSILGLWGTHDRSIWWADGAFLFIIGFFLFGPQMMIGLAAAELSHKKAAGTASGFTGW
FAYFGAAFAGYPLGKVAQDWGWHGFFVALLACALIALLFFLPTWNASEQSLRKHSH

Sequences:

>Translated_456_residues
MNLWTKIFQPPRHIKEISDPELVKKQYKYWRVRIFYSMFFGYVFFYFTRKSFTFAMPTLIADLGFDKAQLGIIGSTLYIT
YGISKFVSGVMSDQSNPRYFMATGLIITGLSNIFFGLSSTVPLFVLFWGINGWFQGWGWPPCARLLTHWYSKSERGTWWS
VWSTSHNIGGALIPVLTGIAIDYAGWRGAMFIPGIICIIMGFILIDRLRDTPQSLGLPAIEKFKKEDLSHPHEETTADIL
EEEAERELSTKEILFTYVLSNKWLWFLSFASFFIYVVRMAVNDWSALYLIETKNYSTVKANLCVSLFEIGGLFGMLLAGW
LSDTISKGKRGPMNVVFSLGLLFSILGLWGTHDRSIWWADGAFLFIIGFFLFGPQMMIGLAAAELSHKKAAGTASGFTGW
FAYFGAAFAGYPLGKVAQDWGWHGFFVALLACALIALLFFLPTWNASEQSLRKHSH
>Mature_456_residues
MNLWTKIFQPPRHIKEISDPELVKKQYKYWRVRIFYSMFFGYVFFYFTRKSFTFAMPTLIADLGFDKAQLGIIGSTLYIT
YGISKFVSGVMSDQSNPRYFMATGLIITGLSNIFFGLSSTVPLFVLFWGINGWFQGWGWPPCARLLTHWYSKSERGTWWS
VWSTSHNIGGALIPVLTGIAIDYAGWRGAMFIPGIICIIMGFILIDRLRDTPQSLGLPAIEKFKKEDLSHPHEETTADIL
EEEAERELSTKEILFTYVLSNKWLWFLSFASFFIYVVRMAVNDWSALYLIETKNYSTVKANLCVSLFEIGGLFGMLLAGW
LSDTISKGKRGPMNVVFSLGLLFSILGLWGTHDRSIWWADGAFLFIIGFFLFGPQMMIGLAAAELSHKKAAGTASGFTGW
FAYFGAAFAGYPLGKVAQDWGWHGFFVALLACALIALLFFLPTWNASEQSLRKHSH

Specific function: Transport protein for sugar phosphate uptake

COG id: COG2271

COG function: function code G; Sugar phosphate permease

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family

Homologues:

Organism=Homo sapiens, GI256219598, Length=431, Percent_Identity=34.8027842227378, Blast_Score=248, Evalue=7e-66,
Organism=Homo sapiens, GI4503847, Length=431, Percent_Identity=34.8027842227378, Blast_Score=248, Evalue=7e-66,
Organism=Homo sapiens, GI256219483, Length=431, Percent_Identity=34.8027842227378, Blast_Score=248, Evalue=7e-66,
Organism=Homo sapiens, GI256219543, Length=455, Percent_Identity=32.5274725274725, Blast_Score=246, Evalue=4e-65,
Organism=Homo sapiens, GI256219564, Length=357, Percent_Identity=31.9327731092437, Blast_Score=174, Evalue=2e-43,
Organism=Homo sapiens, GI46361976, Length=463, Percent_Identity=22.6781857451404, Blast_Score=103, Evalue=4e-22,
Organism=Homo sapiens, GI223717983, Length=403, Percent_Identity=26.7990074441687, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI38093649, Length=403, Percent_Identity=26.7990074441687, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI49619231, Length=400, Percent_Identity=24.5, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI14150047, Length=254, Percent_Identity=22.8346456692913, Blast_Score=74, Evalue=3e-13,
Organism=Escherichia coli, GI87082310, Length=440, Percent_Identity=47.5, Blast_Score=422, Evalue=1e-119,
Organism=Escherichia coli, GI1788573, Length=458, Percent_Identity=37.5545851528384, Blast_Score=310, Evalue=1e-85,
Organism=Escherichia coli, GI2367259, Length=435, Percent_Identity=34.0229885057471, Blast_Score=210, Evalue=1e-55,
Organism=Escherichia coli, GI1789152, Length=430, Percent_Identity=21.1627906976744, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI2367379, Length=330, Percent_Identity=22.7272727272727, Blast_Score=69, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17542316, Length=456, Percent_Identity=23.9035087719298, Blast_Score=108, Evalue=8e-24,
Organism=Caenorhabditis elegans, GI133930953, Length=464, Percent_Identity=22.6293103448276, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17561094, Length=421, Percent_Identity=23.9904988123515, Blast_Score=97, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI133901854, Length=481, Percent_Identity=21.8295218295218, Blast_Score=86, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17539138, Length=297, Percent_Identity=25.5892255892256, Blast_Score=86, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI133901856, Length=473, Percent_Identity=22.1987315010571, Blast_Score=86, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17564202, Length=457, Percent_Identity=20.1312910284464, Blast_Score=76, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17564204, Length=394, Percent_Identity=20.3045685279188, Blast_Score=73, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24656866, Length=488, Percent_Identity=24.5901639344262, Blast_Score=113, Evalue=3e-25,
Organism=Drosophila melanogaster, GI45550478, Length=488, Percent_Identity=24.5901639344262, Blast_Score=113, Evalue=3e-25,
Organism=Drosophila melanogaster, GI24656861, Length=487, Percent_Identity=24.2299794661191, Blast_Score=112, Evalue=4e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UHPT_CHLMU (Q9PJJ8)

Other databases:

- EMBL:   AE002160
- PIR:   G81660
- RefSeq:   NP_297204.1
- ProteinModelPortal:   Q9PJJ8
- GeneID:   1246199
- GenomeReviews:   AE002160_GR
- KEGG:   cmu:TC0831
- TIGR:   TC_0831
- HOGENOM:   HBG559184
- OMA:   QDANIAD
- PhylomeDB:   Q9PJJ8
- ProtClustDB:   CLSK871435
- BioCyc:   CMUR243161:TC_0831-MONOMER
- InterPro:   IPR000849
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR021159
- TIGRFAMs:   TIGR00881

Pfam domain/function: PF07690 MFS_1; SSF103473 MFS_gen_substrate_transporter

EC number: NA

Molecular weight: Translated: 51652; Mature: 51652

Theoretical pI: Translated: 9.13; Mature: 9.13

Prosite motif: PS00942 GLPT; PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xc111538)-; HASH(0x95e26e0)-; HASH(0xc924148)-; HASH(0x403b1450)-; HASH(0xd60e2ac)-; HASH(0xda97ce4)-; HASH(0xd3391a4)-; HASH(0xd637f7c)-; HASH(0xd4cb230)-; HASH(0xb6a400c)-; HASH(0xcd900d8)-;

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLWTKIFQPPRHIKEISDPELVKKQYKYWRVRIFYSMFFGYVFFYFTRKSFTFAMPTLI
CCCCHHHCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
ADLGFDKAQLGIIGSTLYITYGISKFVSGVMSDQSNPRYFMATGLIITGLSNIFFGLSST
HHCCCCHHHHHEEHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHCCH
VPLFVLFWGINGWFQGWGWPPCARLLTHWYSKSERGTWWSVWSTSHNIGGALIPVLTGIA
HHHHHHHHCCCHHCCCCCCCHHHHHHHHHHCCCCCCCEEEEECCCCCCCHHHHHHHHHHH
IDYAGWRGAMFIPGIICIIMGFILIDRLRDTPQSLGLPAIEKFKKEDLSHPHEETTADIL
HCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHCCCHHHHHHHHHHCCCCCHHHHHHHH
EEEAERELSTKEILFTYVLSNKWLWFLSFASFFIYVVRMAVNDWSALYLIETKNYSTVKA
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCHHH
NLCVSLFEIGGLFGMLLAGWLSDTISKGKRGPMNVVFSLGLLFSILGLWGTHDRSIWWAD
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEC
GAFLFIIGFFLFGPQMMIGLAAAELSHKKAAGTASGFTGWFAYFGAAFAGYPLGKVAQDW
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHC
GWHGFFVALLACALIALLFFLPTWNASEQSLRKHSH
CHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCH
>Mature Secondary Structure
MNLWTKIFQPPRHIKEISDPELVKKQYKYWRVRIFYSMFFGYVFFYFTRKSFTFAMPTLI
CCCCHHHCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
ADLGFDKAQLGIIGSTLYITYGISKFVSGVMSDQSNPRYFMATGLIITGLSNIFFGLSST
HHCCCCHHHHHEEHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHCCH
VPLFVLFWGINGWFQGWGWPPCARLLTHWYSKSERGTWWSVWSTSHNIGGALIPVLTGIA
HHHHHHHHCCCHHCCCCCCCHHHHHHHHHHCCCCCCCEEEEECCCCCCCHHHHHHHHHHH
IDYAGWRGAMFIPGIICIIMGFILIDRLRDTPQSLGLPAIEKFKKEDLSHPHEETTADIL
HCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHCCCHHHHHHHHHHCCCCCHHHHHHHH
EEEAERELSTKEILFTYVLSNKWLWFLSFASFFIYVVRMAVNDWSALYLIETKNYSTVKA
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCHHH
NLCVSLFEIGGLFGMLLAGWLSDTISKGKRGPMNVVFSLGLLFSILGLWGTHDRSIWWAD
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEC
GAFLFIIGFFLFGPQMMIGLAAAELSHKKAAGTASGFTGWFAYFGAAFAGYPLGKVAQDW
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHC
GWHGFFVALLACALIALLFFLPTWNASEQSLRKHSH
CHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10684935