Click here to switch to the map view.

The map label for this gene is mip

Identifier: 15835442

GI number: 15835442

Start: 959084

End: 959869

Strand: Reverse

Name: mip

Synonym: TC0828

Alternate gene names: 15835442

Gene position: 959869-959084 (Counterclockwise)

Preceding gene: 15835443

Following gene: 15835441

Centisome position: 89.46

GC content: 38.17

Gene sequence:

>786_bases
ATGGTTTTAAAAAAAGCGCGTCTGAGAAATCGGGTGCAACTAAGGAAGAAACGAATGAAAAATATATTAAGTTGGATGCT
TATGTTTGCAGTCGCCCTGCCTATTTTAGGGTGCGATAATAACGGTGGTTCGCAAACATCTGCGATGGGGAAAGACATGG
TAGAAGATTCTGTACTCACAGACAATCAAAAATTATCAAGAACCTTCGGACATTTGTTAGCTCGACAATTGAGTTCCACA
GAAGATTTTACATTAGATCTTACTGAGGTTATTAAAGGCATGCAGTCTGAAATAGAAGGAAAAAGTGCTCCTTTGACGGA
TTCTGAATACGAAACGCAAATGGCTTTAGTGCAGAAGGCAAGTTTTGAGAAAAAATGTTCAGAGAATTTAGCTTCTGCAG
AAAAATTCTTGAAAGAGAATAAAGATAAAGAAGGTGTAATTGAGCTAGAGCCTAATAAGTTACAGTACCGTATCGTAAAA
GAAGGAACGGGACGAGTTCTTACGGGTAAACCTAACGCTTTATTGCACTACACAGGAAGTTTCATCAATGGGAAAGTTTT
TGACACTTCTGAGAAAAATAAGGACCCTATTTTACTGCCTTTGACAAAAGTCATTTCTGGATTCTCTCAAGGAATGCAAG
GAATGCGAGAAGGAGAAGTTCGGGTTCTGTATATACATCCTGATTTAGCTTATGGAACATCAGGACAATTGCCTCCAAAT
TCCTTACTCATTTTTGAAGTGAAGTTAATTGAGGCAAATGACGATAATGTATCCGTTGCGGAGTAA

Upstream 100 bases:

>100_bases
GAATTGGGGCTGAAACTGTAATATCGTTTCTGCTCTAAAAGTTGAGAAAACGAGCTTTTTTTTACAGTGGGTGATAGGTG
CAGGTCTTTTACTTGAGTAA

Downstream 100 bases:

>100_bases
TTATTAGGATTTTTTATGCGCATAGTTCTTCATAATCCGGATATTCCTCAAAATACAGGGAATATTGGTAGAACGTGTGT
AGCTTTGGGGGCCGAGCTAA

Product: peptidyl-prolyl cis-trans isomerase Mip

Products: NA

Alternate protein names: PPIase; Rotamase [H]

Number of amino acids: Translated: 261; Mature: 261

Protein sequence:

>261_residues
MVLKKARLRNRVQLRKKRMKNILSWMLMFAVALPILGCDNNGGSQTSAMGKDMVEDSVLTDNQKLSRTFGHLLARQLSST
EDFTLDLTEVIKGMQSEIEGKSAPLTDSEYETQMALVQKASFEKKCSENLASAEKFLKENKDKEGVIELEPNKLQYRIVK
EGTGRVLTGKPNALLHYTGSFINGKVFDTSEKNKDPILLPLTKVISGFSQGMQGMREGEVRVLYIHPDLAYGTSGQLPPN
SLLIFEVKLIEANDDNVSVAE

Sequences:

>Translated_261_residues
MVLKKARLRNRVQLRKKRMKNILSWMLMFAVALPILGCDNNGGSQTSAMGKDMVEDSVLTDNQKLSRTFGHLLARQLSST
EDFTLDLTEVIKGMQSEIEGKSAPLTDSEYETQMALVQKASFEKKCSENLASAEKFLKENKDKEGVIELEPNKLQYRIVK
EGTGRVLTGKPNALLHYTGSFINGKVFDTSEKNKDPILLPLTKVISGFSQGMQGMREGEVRVLYIHPDLAYGTSGQLPPN
SLLIFEVKLIEANDDNVSVAE
>Mature_261_residues
MVLKKARLRNRVQLRKKRMKNILSWMLMFAVALPILGCDNNGGSQTSAMGKDMVEDSVLTDNQKLSRTFGHLLARQLSST
EDFTLDLTEVIKGMQSEIEGKSAPLTDSEYETQMALVQKASFEKKCSENLASAEKFLKENKDKEGVIELEPNKLQYRIVK
EGTGRVLTGKPNALLHYTGSFINGKVFDTSEKNKDPILLPLTKVISGFSQGMQGMREGEVRVLYIHPDLAYGTSGQLPPN
SLLIFEVKLIEANDDNVSVAE

Specific function: PPIases accelerate the folding of proteins [H]

COG id: COG0545

COG function: function code O; FKBP-type peptidyl-prolyl cis-trans isomerases 1

Gene ontology:

Cell location: Cell outer membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase FKBP-type domain [H]

Homologues:

Organism=Homo sapiens, GI4758380, Length=103, Percent_Identity=36.8932038834951, Blast_Score=65, Evalue=5e-11,
Organism=Escherichia coli, GI1789745, Length=206, Percent_Identity=29.6116504854369, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI87082390, Length=202, Percent_Identity=31.1881188118812, Blast_Score=86, Evalue=2e-18,

Paralogues:

None

Copy number: 200 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001179
- InterPro:   IPR000774 [H]

Pfam domain/function: PF00254 FKBP_C; PF01346 FKBP_N [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 29058; Mature: 29058

Theoretical pI: Translated: 8.19; Mature: 8.19

Prosite motif: PS50059 FKBP_PPIASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVLKKARLRNRVQLRKKRMKNILSWMLMFAVALPILGCDNNGGSQTSAMGKDMVEDSVLT
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHC
DNQKLSRTFGHLLARQLSSTEDFTLDLTEVIKGMQSEIEGKSAPLTDSEYETQMALVQKA
CCHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
SFEKKCSENLASAEKFLKENKDKEGVIELEPNKLQYRIVKEGTGRVLTGKPNALLHYTGS
HHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCEEEEEEECCCCEEEECCCCEEEEECCC
FINGKVFDTSEKNKDPILLPLTKVISGFSQGMQGMREGEVRVLYIHPDLAYGTSGQLPPN
CCCCEEECCCCCCCCCEEEEHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCC
SLLIFEVKLIEANDDNVSVAE
CEEEEEEEEEECCCCCCCCCC
>Mature Secondary Structure
MVLKKARLRNRVQLRKKRMKNILSWMLMFAVALPILGCDNNGGSQTSAMGKDMVEDSVLT
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHC
DNQKLSRTFGHLLARQLSSTEDFTLDLTEVIKGMQSEIEGKSAPLTDSEYETQMALVQKA
CCHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
SFEKKCSENLASAEKFLKENKDKEGVIELEPNKLQYRIVKEGTGRVLTGKPNALLHYTGS
HHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCEEEEEEECCCCEEEECCCCEEEEECCC
FINGKVFDTSEKNKDPILLPLTKVISGFSQGMQGMREGEVRVLYIHPDLAYGTSGQLPPN
CCCCEEECCCCCCCCCEEEEHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCC
SLLIFEVKLIEANDDNVSVAE
CEEEEEEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10684935 [H]