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Identifier: 15835436

GI number: 15835436

Start: 954999

End: 955478

Strand: Reverse

Name: Not Available

Synonym: TC0822

Alternate gene names: 15835436

Gene position: 955478-954999 (Counterclockwise)

Preceding gene: 15835437

Following gene: 15835435

Centisome position: 89.05

GC content: 38.75

Gene sequence:

>480_bases
GTGAGGAAGAATATTAAAGATAAAAAGAAAACAGTTTCTGCCAGTTGTATAAACGATCACATCTATAAAATATTTCCTAA
CGACTTGAATACAAATAATACTATCTTTGGCGGATTACTCATGAGTTTATTGGATCGGTTAGCTTTAGTGGTTGCCGAAC
GTCATTGTGAAAGTATTTGTGTAACAGCTCTTGTAGATGCTGTGCGTTTTTATGCTCCCGCTTACATGGGAGAAAATCTC
ATTTGCTGTGCTTCTGTGAATCGCTCTTGGCGAACTTCTTTAGAAGTTGGAGTAAAAGTTTGGGCGGAAAATATTTATAA
ACAGGAACAGCGACATATCACTTCTGCGTATTTTACATTTGTTGCGGTAGACGAAAATAATTCTCCTGTGGAAATTCCAG
AGCTAGTCCCTGAAACCCAAGAAGAAATTCGGCGTTTCCATGAAGCTGACCAGAGAAGAGCTTCCCGATTGAAACTGTGA

Upstream 100 bases:

>100_bases
CGGTACTACTATCCGCTACAGAGCAGGCTGGGGGATAGAGAGGGATCAATAACTCTAAGACTGGTCGGGATAGAGACTAT
TTGGTGTATAGAAGGTTTCT

Downstream 100 bases:

>100_bases
ACTACGTTTTGAGGGATTCTTTTCTTATTTTCTGTCTTTAATGCAAGCTAATGAGGAGTCCCACCCGTGTTTAAGAGTGT
TTTGTATATTGGCCTTTCCT

Product: cytosolic acyl-CoA thioester hydrolase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 159; Mature: 159

Protein sequence:

>159_residues
MRKNIKDKKKTVSASCINDHIYKIFPNDLNTNNTIFGGLLMSLLDRLALVVAERHCESICVTALVDAVRFYAPAYMGENL
ICCASVNRSWRTSLEVGVKVWAENIYKQEQRHITSAYFTFVAVDENNSPVEIPELVPETQEEIRRFHEADQRRASRLKL

Sequences:

>Translated_159_residues
MRKNIKDKKKTVSASCINDHIYKIFPNDLNTNNTIFGGLLMSLLDRLALVVAERHCESICVTALVDAVRFYAPAYMGENL
ICCASVNRSWRTSLEVGVKVWAENIYKQEQRHITSAYFTFVAVDENNSPVEIPELVPETQEEIRRFHEADQRRASRLKL
>Mature_159_residues
MRKNIKDKKKTVSASCINDHIYKIFPNDLNTNNTIFGGLLMSLLDRLALVVAERHCESICVTALVDAVRFYAPAYMGENL
ICCASVNRSWRTSLEVGVKVWAENIYKQEQRHITSAYFTFVAVDENNSPVEIPELVPETQEEIRRFHEADQRRASRLKL

Specific function: Unknown

COG id: COG1607

COG function: function code I; Acyl-CoA hydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl coenzyme A hydrolase family

Homologues:

Organism=Homo sapiens, GI32528284, Length=134, Percent_Identity=32.8358208955224, Blast_Score=86, Evalue=1e-17,
Organism=Homo sapiens, GI22165400, Length=138, Percent_Identity=33.3333333333333, Blast_Score=86, Evalue=1e-17,
Organism=Homo sapiens, GI32528286, Length=134, Percent_Identity=32.8358208955224, Blast_Score=86, Evalue=1e-17,
Organism=Homo sapiens, GI22165355, Length=138, Percent_Identity=33.3333333333333, Blast_Score=86, Evalue=1e-17,
Organism=Homo sapiens, GI75709208, Length=134, Percent_Identity=32.8358208955224, Blast_Score=86, Evalue=1e-17,
Organism=Homo sapiens, GI32528282, Length=134, Percent_Identity=32.8358208955224, Blast_Score=86, Evalue=1e-17,
Organism=Homo sapiens, GI18640736, Length=141, Percent_Identity=30.4964539007092, Blast_Score=79, Evalue=2e-15,
Organism=Escherichia coli, GI1787506, Length=112, Percent_Identity=32.1428571428571, Blast_Score=65, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y822_CHLMU (Q9PJK7)

Other databases:

- EMBL:   AE002160
- PIR:   C81662
- RefSeq:   NP_297195.1
- ProteinModelPortal:   Q9PJK7
- SMR:   Q9PJK7
- GeneID:   1246189
- GenomeReviews:   AE002160_GR
- KEGG:   cmu:TC0822
- TIGR:   TC_0822
- HOGENOM:   HBG499693
- OMA:   TFVAIKD
- ProtClustDB:   CLSK871429
- BioCyc:   CMUR243161:TC_0822-MONOMER
- InterPro:   IPR006683

Pfam domain/function: PF03061 4HBT

EC number: 3.1.2.- [C]

Molecular weight: Translated: 18248; Mature: 18248

Theoretical pI: Translated: 7.88; Mature: 7.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.1 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
3.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKNIKDKKKTVSASCINDHIYKIFPNDLNTNNTIFGGLLMSLLDRLALVVAERHCESIC
CCCCCCHHHHHHHHHHHHCHHEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
VTALVDAVRFYAPAYMGENLICCASVNRSWRTSLEVGVKVWAENIYKQEQRHITSAYFTF
HHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEE
VAVDENNSPVEIPELVPETQEEIRRFHEADQRRASRLKL
EEECCCCCCEECHHHCCCHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRKNIKDKKKTVSASCINDHIYKIFPNDLNTNNTIFGGLLMSLLDRLALVVAERHCESIC
CCCCCCHHHHHHHHHHHHCHHEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
VTALVDAVRFYAPAYMGENLICCASVNRSWRTSLEVGVKVWAENIYKQEQRHITSAYFTF
HHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEE
VAVDENNSPVEIPELVPETQEEIRRFHEADQRRASRLKL
EEECCCCCCEECHHHCCCHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on ester bonds; Thiolester hydrolases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10684935