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The map label for this gene is lnt

Identifier: 15835435

GI number: 15835435

Start: 953304

End: 954932

Strand: Reverse

Name: lnt

Synonym: TC0821

Alternate gene names: 15835435

Gene position: 954932-953304 (Counterclockwise)

Preceding gene: 15835436

Following gene: 15835434

Centisome position: 89.0

GC content: 42.17

Gene sequence:

>1629_bases
GTGTTTAAGAGTGTTTTGTATATTGGCCTTTCCTGGGTTCTAGTCTGTTTTGCTCAGCCTGATATCAGCACTTTAGCTTC
TGTGATATGCTGCATGTGTGGATATGGATTGCTTTGGCGGGGGCTTCTTTCTTTAGTAGATAGCTCGTCCTGGAGGAAGA
TCTGGTGTCTAGCCTTTTTTTGGACTTGGTCCGTTGAAGGTTTTCATTTTTCATGGATGCTTGAAGATTTTTATGTAGGG
ACAAGTATCTACTTCGTTTGGTGCCTACTTATTTCTTATCTTGCAGTTACTTTCGCAAGTTTTTCTTGTCTTGTCGTACT
CTGTTTCCGCAAGCAATATTGGGGGGCTCTGTTTTGGCTCCCCGGAGTTTGGGTAGCTATAGAGTCTGTGCGCTATTATG
GGTTGCTTTCGGGAGTTTCTTTTGATTTCATTGGCTGGCCTCTTGCAGCAACAGCTTATGGAAGGCAATTTGGAAGCTTT
TTTGGATGGGCGGGGCAGAGCTTTGTAGTCATTGCTACCAATTTAGGATGCTGTTCGGTATTAGTCTTTAGAAAATCTTT
TTCTTACGGATTATGGCTGGTATGCTGTGCTTTCCCTTATTTTTTAGGAGGAACTTATTACGAATATGTAAGAAGGCATT
TTTCTAATGAGGAGGTTCTTCGAGTTGCTATTGTGCAACCGGGGTACAGTCCCCATATGCAAGGAGCAAGGACCGCTAGT
GCTATTTGGAGTAATCTAGTTTCTTTATGCCAAGGTATTTGTCCTCCCGTAGATGTCATTGTTTTCCCTGAGGTCAGCGT
TCCTTTTGGTTTGCATAGGCAAGCATATTCTTTCCATGAAAATCAACAAGTTTTAGAGAGTCTGGTTCCTAATAAATTTT
GGAACGAGTTTTTTACAAACCTAGATTGGATTCGTGCACTATCAGAACGTTTTCAATGTGCTGTTATCATGGGGATGGAA
AGATGGGAAGATAAAAATGGGGTTATGCACTTGTACAATGCTGCTGAATGTTTGTCTTTGCAAGGGGAAGTTACCAGCTA
TGATAAGCGCATTCTTGTGCCTGGAGGGGAATATATTCCCGGAGGTAAGTTTGGTTTTTCTTTATGCAAAGCCTTTTTTC
CTGAGTTTGCGCTCCCTTTTCAACGGCTTCCCGGGGAAAAATCTGGGATTGTACAGATCACAGAGCGAATAAAAGCTGGG
ATCTCTATCTGTTATGAAGAGACTTTTGGTTATGCAATTCTCCCATATAAAAGGCAGAAAGCGGATATTTTAGTGAATCT
TACTAATGATGGGTGGTACCCACATTCACGGCTCCCTCTAGTCCATTTTTATCATGGTGTTTTACGTAACCAAGAACTAG
GAATGCCTTGTATTCGAGCTTGTCACACAGGGGTGTCTGCGGCAGTAGATTCTTTAGGAAGAATTGTTGGAGTGCTCCCT
TGGGAGTCAAAAACTTGCCCTGTTTGTCCAGATGTTCTTCAGGTCTCTGTTCCTGTTTACAGTTATCCTACTATATATGC
AAAGTTCGGAGATGCGCCGTTATTATTCGTGGCAGTAAGTTCCGTTTTAGGAGTAGTAGGTTATTTTTTAAAGAGACGGG
GAAAGACCCTAACAGGGAGTGACATTTGA

Upstream 100 bases:

>100_bases
TGACCAGAGAAGAGCTTCCCGATTGAAACTGTGAACTACGTTTTGAGGGATTCTTTTCTTATTTTCTGTCTTTAATGCAA
GCTAATGAGGAGTCCCACCC

Downstream 100 bases:

>100_bases
AATAGCAAGTGTTTCAAAACTAATCAGTAATTTTTTGATATCGCTTGCTTGCTAAAAAAAAAAAAGGATAATATACGGGG
TCTCTTTGTCAAGGTTTTGC

Product: apolipoprotein N-acyltransferase

Products: NA

Alternate protein names: ALP N-acyltransferase

Number of amino acids: Translated: 542; Mature: 542

Protein sequence:

>542_residues
MFKSVLYIGLSWVLVCFAQPDISTLASVICCMCGYGLLWRGLLSLVDSSSWRKIWCLAFFWTWSVEGFHFSWMLEDFYVG
TSIYFVWCLLISYLAVTFASFSCLVVLCFRKQYWGALFWLPGVWVAIESVRYYGLLSGVSFDFIGWPLAATAYGRQFGSF
FGWAGQSFVVIATNLGCCSVLVFRKSFSYGLWLVCCAFPYFLGGTYYEYVRRHFSNEEVLRVAIVQPGYSPHMQGARTAS
AIWSNLVSLCQGICPPVDVIVFPEVSVPFGLHRQAYSFHENQQVLESLVPNKFWNEFFTNLDWIRALSERFQCAVIMGME
RWEDKNGVMHLYNAAECLSLQGEVTSYDKRILVPGGEYIPGGKFGFSLCKAFFPEFALPFQRLPGEKSGIVQITERIKAG
ISICYEETFGYAILPYKRQKADILVNLTNDGWYPHSRLPLVHFYHGVLRNQELGMPCIRACHTGVSAAVDSLGRIVGVLP
WESKTCPVCPDVLQVSVPVYSYPTIYAKFGDAPLLFVAVSSVLGVVGYFLKRRGKTLTGSDI

Sequences:

>Translated_542_residues
MFKSVLYIGLSWVLVCFAQPDISTLASVICCMCGYGLLWRGLLSLVDSSSWRKIWCLAFFWTWSVEGFHFSWMLEDFYVG
TSIYFVWCLLISYLAVTFASFSCLVVLCFRKQYWGALFWLPGVWVAIESVRYYGLLSGVSFDFIGWPLAATAYGRQFGSF
FGWAGQSFVVIATNLGCCSVLVFRKSFSYGLWLVCCAFPYFLGGTYYEYVRRHFSNEEVLRVAIVQPGYSPHMQGARTAS
AIWSNLVSLCQGICPPVDVIVFPEVSVPFGLHRQAYSFHENQQVLESLVPNKFWNEFFTNLDWIRALSERFQCAVIMGME
RWEDKNGVMHLYNAAECLSLQGEVTSYDKRILVPGGEYIPGGKFGFSLCKAFFPEFALPFQRLPGEKSGIVQITERIKAG
ISICYEETFGYAILPYKRQKADILVNLTNDGWYPHSRLPLVHFYHGVLRNQELGMPCIRACHTGVSAAVDSLGRIVGVLP
WESKTCPVCPDVLQVSVPVYSYPTIYAKFGDAPLLFVAVSSVLGVVGYFLKRRGKTLTGSDI
>Mature_542_residues
MFKSVLYIGLSWVLVCFAQPDISTLASVICCMCGYGLLWRGLLSLVDSSSWRKIWCLAFFWTWSVEGFHFSWMLEDFYVG
TSIYFVWCLLISYLAVTFASFSCLVVLCFRKQYWGALFWLPGVWVAIESVRYYGLLSGVSFDFIGWPLAATAYGRQFGSF
FGWAGQSFVVIATNLGCCSVLVFRKSFSYGLWLVCCAFPYFLGGTYYEYVRRHFSNEEVLRVAIVQPGYSPHMQGARTAS
AIWSNLVSLCQGICPPVDVIVFPEVSVPFGLHRQAYSFHENQQVLESLVPNKFWNEFFTNLDWIRALSERFQCAVIMGME
RWEDKNGVMHLYNAAECLSLQGEVTSYDKRILVPGGEYIPGGKFGFSLCKAFFPEFALPFQRLPGEKSGIVQITERIKAG
ISICYEETFGYAILPYKRQKADILVNLTNDGWYPHSRLPLVHFYHGVLRNQELGMPCIRACHTGVSAAVDSLGRIVGVLP
WESKTCPVCPDVLQVSVPVYSYPTIYAKFGDAPLLFVAVSSVLGVVGYFLKRRGKTLTGSDI

Specific function: Transfers the fatty acyl group on membrane lipoproteins

COG id: COG0815

COG function: function code M; Apolipoprotein N-acyltransferase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 CN hydrolase domain

Homologues:

Organism=Escherichia coli, GI1786878, Length=225, Percent_Identity=26.6666666666667, Blast_Score=73, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): LNT_CHLMU (Q9PJK8)

Other databases:

- EMBL:   AE002160
- PIR:   B81662
- RefSeq:   NP_297194.1
- ProteinModelPortal:   Q9PJK8
- GeneID:   1246188
- GenomeReviews:   AE002160_GR
- KEGG:   cmu:TC0821
- TIGR:   TC_0821
- HOGENOM:   HBG402731
- OMA:   GRQFGGF
- ProtClustDB:   PRK00302
- BioCyc:   CMUR243161:TC_0821-MONOMER
- HAMAP:   MF_01148
- InterPro:   IPR004563
- InterPro:   IPR003010
- Gene3D:   G3DSA:3.60.110.10
- TIGRFAMs:   TIGR00546

Pfam domain/function: PF00795 CN_hydrolase; SSF56317 Ntlse/CNhydtse

EC number: 2.3.1.- [C]

Molecular weight: Translated: 61184; Mature: 61184

Theoretical pI: Translated: 7.86; Mature: 7.86

Prosite motif: PS50263 CN_HYDROLASE

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xbf2253c)-; HASH(0xcf6e1c8)-; HASH(0xbe4de90)-; HASH(0xc9a2e74)-; HASH(0xda754b4)-; HASH(0xd4fb76c)-; HASH(0xd2621ec)-; HASH(0xca1d618)-;

Cys/Met content:

4.1 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
4.1 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFKSVLYIGLSWVLVCFAQPDISTLASVICCMCGYGLLWRGLLSLVDSSSWRKIWCLAFF
CCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCCHHHEEEH
WTWSVEGFHFSWMLEDFYVGTSIYFVWCLLISYLAVTFASFSCLVVLCFRKQYWGALFWL
HHHEECCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PGVWVAIESVRYYGLLSGVSFDFIGWPLAATAYGRQFGSFFGWAGQSFVVIATNLGCCSV
HHHHHHHHHHHHHHHHCCCCCHHCCCCHHHHHHHHHHHHHHCCCCCEEEEEEECCCHHHH
LVFRKSFSYGLWLVCCAFPYFLGGTYYEYVRRHFSNEEVLRVAIVQPGYSPHMQGARTAS
HHHHHCCCCHHHHHHHHHHHHHCCHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCHHHHH
AIWSNLVSLCQGICPPVDVIVFPEVSVPFGLHRQAYSFHENQQVLESLVPNKFWNEFFTN
HHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHCC
LDWIRALSERFQCAVIMGMERWEDKNGVMHLYNAAECLSLQGEVTSYDKRILVPGGEYIP
HHHHHHHHHHCCEEEEECHHHHCCCCCEEEEECHHHHHHCCCCCCCCCCEEECCCCCCCC
GGKFGFSLCKAFFPEFALPFQRLPGEKSGIVQITERIKAGISICYEETFGYAILPYKRQK
CCHHHHHHHHHHHHHHCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEECCCCCC
ADILVNLTNDGWYPHSRLPLVHFYHGVLRNQELGMPCIRACHTGVSAAVDSLGRIVGVLP
CEEEEEECCCCCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHCCHHHHHHHHHHHEEECC
WESKTCPVCPDVLQVSVPVYSYPTIYAKFGDAPLLFVAVSSVLGVVGYFLKRRGKTLTGS
CCCCCCCCCCHHHHEECCCEECCEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCC
DI
CH
>Mature Secondary Structure
MFKSVLYIGLSWVLVCFAQPDISTLASVICCMCGYGLLWRGLLSLVDSSSWRKIWCLAFF
CCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCCHHHEEEH
WTWSVEGFHFSWMLEDFYVGTSIYFVWCLLISYLAVTFASFSCLVVLCFRKQYWGALFWL
HHHEECCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PGVWVAIESVRYYGLLSGVSFDFIGWPLAATAYGRQFGSFFGWAGQSFVVIATNLGCCSV
HHHHHHHHHHHHHHHHCCCCCHHCCCCHHHHHHHHHHHHHHCCCCCEEEEEEECCCHHHH
LVFRKSFSYGLWLVCCAFPYFLGGTYYEYVRRHFSNEEVLRVAIVQPGYSPHMQGARTAS
HHHHHCCCCHHHHHHHHHHHHHCCHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCHHHHH
AIWSNLVSLCQGICPPVDVIVFPEVSVPFGLHRQAYSFHENQQVLESLVPNKFWNEFFTN
HHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHCC
LDWIRALSERFQCAVIMGMERWEDKNGVMHLYNAAECLSLQGEVTSYDKRILVPGGEYIP
HHHHHHHHHHCCEEEEECHHHHCCCCCEEEEECHHHHHHCCCCCCCCCCEEECCCCCCCC
GGKFGFSLCKAFFPEFALPFQRLPGEKSGIVQITERIKAGISICYEETFGYAILPYKRQK
CCHHHHHHHHHHHHHHCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEECCCCCC
ADILVNLTNDGWYPHSRLPLVHFYHGVLRNQELGMPCIRACHTGVSAAVDSLGRIVGVLP
CEEEEEECCCCCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHCCHHHHHHHHHHHEEECC
WESKTCPVCPDVLQVSVPVYSYPTIYAKFGDAPLLFVAVSSVLGVVGYFLKRRGKTLTGS
CCCCCCCCCCHHHHEECCCEECCEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCC
DI
CH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Transferases; Acyltransferases; Transferring groups other than amino-acyl groups [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10684935