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The map label for this gene is gap

Identifier: 15835406

GI number: 15835406

Start: 935384

End: 936391

Strand: Reverse

Name: gap

Synonym: TC0792

Alternate gene names: 15835406

Gene position: 936391-935384 (Counterclockwise)

Preceding gene: 15835407

Following gene: 15835405

Centisome position: 87.27

GC content: 40.58

Gene sequence:

>1008_bases
ATGAGAATTGTGATTAATGGTTTTGGACGAATTGGGCGATTAGTTTTAAGACAGATTCTGAAAAGGAATGCTCCCATAGA
AGTTGTAGCTATTAATGATTTGGTCTCAGGAGATCTTCTAACGTATTTGTTTAAGTATGATTCCACTCACGGATCTTTCG
CTTCGCAGGCAACATTCTCTGATGGATGTTTGGTTGTTGGAGAAAGAAAGATCCGTTTCTTAGCAGAGAAAGACGTTCAA
AAGCTTCCTTGGAAAGATTTGGATGTTGATGTCGTCGTTGAAAGTACTGGGTTATTTGTTAATAAAGATGATGCCGCAAA
GCACTTGGATTCTGGTGCTAAGCGAGTATTAATAACAGCTCCTGCTAAAGGAGATGTCCCTACATTTGTTATGGGAGTCA
ATCATCAAAAGTTTGATCCAGCAAATGACGTAATCATTTCTAATGCTTCTTGCACAACCAATTGTTTAGCGCCTCTAGCC
AAAGTTTTGTTGGATAATTTTGGTATAGAAGAAGGGTTGATGACAACAGTTCATGCGGCAACGGCTACACAAAGTGTGGT
TGATGGTCCTTCTCGGAAAGATTGGAGAGGGGGAAGAGGAGCTTTCCAAAATATTATCCCAGCCTCAACAGGAGCCGCTA
AAGCTGTAGGGTTATGCTTGCCTGAGCTTAAAGGGAAATTGACAGGAATGGCGTTTAGAGTGCCTGTTGCAGATGTTTCT
GTGGTAGACCTGACAGTTAAATTGAGTTCAGCTACAACCTATGAGGCTGTCTGCGAAGCTGTGAAGCATGCAGCAAGTAC
GAGTATGCGGAATATTATGCATTACACAGAAGAAGCTGTAGTTTCTTCTGATTTTATTGGTTGTGAGTATTCGTCTGTAT
TCGATGCCCAAGCCGGGGTTGCTTTGAATGATCGATTTTTCAAATTGATAGCTTGGTATGATAATGAAATAGGCTATGCA
ACTCGCATAGTAGATTTATTAGAGTACATACAAGGAAACTCGAAATAA

Upstream 100 bases:

>100_bases
TTGCAAAATAGGGTTGGTGATAATGCTCAAAAGTGTATTATAGAATTTTTAGCCGATTAGTGCTAATTTTTCGAAAATAC
TGACTACCTGGGATTTAGCA

Downstream 100 bases:

>100_bases
AGGTTAGTTCGTGTATTTTACAAGAGATCCAGTCATAGAGACTGTTATTACATCTAGAGAGGGATATAAGTTATCCATTC
GCAATTCTAAACACCTTTCT

Product: glyceraldehyde-3-phosphate dehydrogenase

Products: NA

Alternate protein names: GAPDH

Number of amino acids: Translated: 335; Mature: 335

Protein sequence:

>335_residues
MRIVINGFGRIGRLVLRQILKRNAPIEVVAINDLVSGDLLTYLFKYDSTHGSFASQATFSDGCLVVGERKIRFLAEKDVQ
KLPWKDLDVDVVVESTGLFVNKDDAAKHLDSGAKRVLITAPAKGDVPTFVMGVNHQKFDPANDVIISNASCTTNCLAPLA
KVLLDNFGIEEGLMTTVHAATATQSVVDGPSRKDWRGGRGAFQNIIPASTGAAKAVGLCLPELKGKLTGMAFRVPVADVS
VVDLTVKLSSATTYEAVCEAVKHAASTSMRNIMHYTEEAVVSSDFIGCEYSSVFDAQAGVALNDRFFKLIAWYDNEIGYA
TRIVDLLEYIQGNSK

Sequences:

>Translated_335_residues
MRIVINGFGRIGRLVLRQILKRNAPIEVVAINDLVSGDLLTYLFKYDSTHGSFASQATFSDGCLVVGERKIRFLAEKDVQ
KLPWKDLDVDVVVESTGLFVNKDDAAKHLDSGAKRVLITAPAKGDVPTFVMGVNHQKFDPANDVIISNASCTTNCLAPLA
KVLLDNFGIEEGLMTTVHAATATQSVVDGPSRKDWRGGRGAFQNIIPASTGAAKAVGLCLPELKGKLTGMAFRVPVADVS
VVDLTVKLSSATTYEAVCEAVKHAASTSMRNIMHYTEEAVVSSDFIGCEYSSVFDAQAGVALNDRFFKLIAWYDNEIGYA
TRIVDLLEYIQGNSK
>Mature_335_residues
MRIVINGFGRIGRLVLRQILKRNAPIEVVAINDLVSGDLLTYLFKYDSTHGSFASQATFSDGCLVVGERKIRFLAEKDVQ
KLPWKDLDVDVVVESTGLFVNKDDAAKHLDSGAKRVLITAPAKGDVPTFVMGVNHQKFDPANDVIISNASCTTNCLAPLA
KVLLDNFGIEEGLMTTVHAATATQSVVDGPSRKDWRGGRGAFQNIIPASTGAAKAVGLCLPELKGKLTGMAFRVPVADVS
VVDLTVKLSSATTYEAVCEAVKHAASTSMRNIMHYTEEAVVSSDFIGCEYSSVFDAQAGVALNDRFFKLIAWYDNEIGYA
TRIVDLLEYIQGNSK

Specific function: Second phase of glycolysis; first step. [C]

COG id: COG0057

COG function: function code G; Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family

Homologues:

Organism=Homo sapiens, GI7657116, Length=332, Percent_Identity=57.5301204819277, Blast_Score=389, Evalue=1e-108,
Organism=Homo sapiens, GI7669492, Length=331, Percent_Identity=57.0996978851964, Blast_Score=378, Evalue=1e-105,
Organism=Escherichia coli, GI1788079, Length=331, Percent_Identity=60.1208459214501, Blast_Score=408, Evalue=1e-115,
Organism=Escherichia coli, GI1789295, Length=328, Percent_Identity=38.719512195122, Blast_Score=231, Evalue=3e-62,
Organism=Caenorhabditis elegans, GI17534677, Length=332, Percent_Identity=57.5301204819277, Blast_Score=384, Evalue=1e-107,
Organism=Caenorhabditis elegans, GI17534679, Length=332, Percent_Identity=57.5301204819277, Blast_Score=383, Evalue=1e-107,
Organism=Caenorhabditis elegans, GI32566163, Length=332, Percent_Identity=57.2289156626506, Blast_Score=375, Evalue=1e-104,
Organism=Caenorhabditis elegans, GI17568413, Length=332, Percent_Identity=57.2289156626506, Blast_Score=375, Evalue=1e-104,
Organism=Saccharomyces cerevisiae, GI6322409, Length=331, Percent_Identity=60.7250755287009, Blast_Score=406, Evalue=1e-114,
Organism=Saccharomyces cerevisiae, GI6322468, Length=331, Percent_Identity=59.5166163141994, Blast_Score=404, Evalue=1e-114,
Organism=Saccharomyces cerevisiae, GI6321631, Length=331, Percent_Identity=59.214501510574, Blast_Score=403, Evalue=1e-113,
Organism=Drosophila melanogaster, GI17933600, Length=331, Percent_Identity=56.4954682779456, Blast_Score=372, Evalue=1e-103,
Organism=Drosophila melanogaster, GI18110149, Length=331, Percent_Identity=56.4954682779456, Blast_Score=372, Evalue=1e-103,
Organism=Drosophila melanogaster, GI85725000, Length=331, Percent_Identity=56.4954682779456, Blast_Score=370, Evalue=1e-103,
Organism=Drosophila melanogaster, GI22023983, Length=331, Percent_Identity=56.4954682779456, Blast_Score=370, Evalue=1e-103,
Organism=Drosophila melanogaster, GI19922412, Length=330, Percent_Identity=56.6666666666667, Blast_Score=364, Evalue=1e-101,

Paralogues:

None

Copy number: 220 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 740 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1660 Molecules/Cell In: Growth Phase, Min

Swissprot (AC and ID): G3P_CHLMU (Q9PJN6)

Other databases:

- EMBL:   AE002160
- PIR:   H81662
- RefSeq:   NP_297165.1
- ProteinModelPortal:   Q9PJN6
- SMR:   Q9PJN6
- GeneID:   1246159
- GenomeReviews:   AE002160_GR
- KEGG:   cmu:TC0792
- TIGR:   TC_0792
- HOGENOM:   HBG571736
- OMA:   DLKWDAI
- PhylomeDB:   Q9PJN6
- ProtClustDB:   CLSK871427
- BioCyc:   CMUR243161:TC_0792-MONOMER
- BRENDA:   1.2.1.12
- GO:   GO:0005737
- GO:   GO:0006096
- InterPro:   IPR020831
- InterPro:   IPR020830
- InterPro:   IPR020829
- InterPro:   IPR020828
- InterPro:   IPR006424
- InterPro:   IPR016040
- Gene3D:   G3DSA:3.40.50.720
- PANTHER:   PTHR10836
- PIRSF:   PIRSF000149
- PRINTS:   PR00078
- SMART:   SM00846
- TIGRFAMs:   TIGR01534

Pfam domain/function: PF02800 Gp_dh_C; PF00044 Gp_dh_N

EC number: =1.2.1.12

Molecular weight: Translated: 36241; Mature: 36241

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS00071 GAPDH

Important sites: ACT_SITE 151-151 BINDING 33-33 BINDING 77-77 BINDING 181-181 BINDING 233-233 BINDING 315-315

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIVINGFGRIGRLVLRQILKRNAPIEVVAINDLVSGDLLTYLFKYDSTHGSFASQATFS
CEEEEECCHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHCCCCCCCCCCCCCC
DGCLVVGERKIRFLAEKDVQKLPWKDLDVDVVVESTGLFVNKDDAAKHLDSGAKRVLITA
CCEEEECCHHHHHHHHHHHHHCCCCCCCEEEEEECCCEEEECCHHHHHHCCCCCEEEEEC
PAKGDVPTFVMGVNHQKFDPANDVIISNASCTTNCLAPLAKVLLDNFGIEEGLMTTVHAA
CCCCCCCEEEEECCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHH
TATQSVVDGPSRKDWRGGRGAFQNIIPASTGAAKAVGLCLPELKGKLTGMAFRVPVADVS
HHHHHHHCCCCCCCCCCCCHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCEEEECCCCCEE
VVDLTVKLSSATTYEAVCEAVKHAASTSMRNIMHYTEEAVVSSDFIGCEYSSVFDAQAGV
EEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCC
ALNDRFFKLIAWYDNEIGYATRIVDLLEYIQGNSK
EECHHHEEEEEEECCCCHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MRIVINGFGRIGRLVLRQILKRNAPIEVVAINDLVSGDLLTYLFKYDSTHGSFASQATFS
CEEEEECCHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHCCCCCCCCCCCCCC
DGCLVVGERKIRFLAEKDVQKLPWKDLDVDVVVESTGLFVNKDDAAKHLDSGAKRVLITA
CCEEEECCHHHHHHHHHHHHHCCCCCCCEEEEEECCCEEEECCHHHHHHCCCCCEEEEEC
PAKGDVPTFVMGVNHQKFDPANDVIISNASCTTNCLAPLAKVLLDNFGIEEGLMTTVHAA
CCCCCCCEEEEECCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHH
TATQSVVDGPSRKDWRGGRGAFQNIIPASTGAAKAVGLCLPELKGKLTGMAFRVPVADVS
HHHHHHHCCCCCCCCCCCCHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCEEEECCCCCEE
VVDLTVKLSSATTYEAVCEAVKHAASTSMRNIMHYTEEAVVSSDFIGCEYSSVFDAQAGV
EEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCC
ALNDRFFKLIAWYDNEIGYATRIVDLLEYIQGNSK
EECHHHEEEEEEECCCCHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10684935