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The map label for this gene is ruvA

Identifier: 15835402

GI number: 15835402

Start: 932430

End: 933032

Strand: Reverse

Name: ruvA

Synonym: TC0788

Alternate gene names: 15835402

Gene position: 933032-932430 (Counterclockwise)

Preceding gene: 15835403

Following gene: 15835401

Centisome position: 86.96

GC content: 39.97

Gene sequence:

>603_bases
ATGTATGAGTATATTAAAGGAAAATTAACCCATACTGATGAAGCTTATGTTGTGATTGAAAGCTTTGGTATAGGCTATTC
TATAATGCTTTCTGAGCGATTTTTAGTAGATCTGCGCGAATTGATGCATCAAGAGGTGCTTATTTATGTTCATAGCGTCA
TTCGCGAAACAGAGCATTCTCTATATGGGTTTAGTTCCCGAGCGGAAAGGGAATGTTTTCGTTTGTTGATTTCTTTTTCT
GGAATCGGTCCCAAAACTGGTTTGGCTATTTTAAACATGTTCCCTCTGCAAGAATTATGTTCAGTCGCTCGTCTAGAAAA
CGTGAAAGCCATCGCTTCTGTTCCTGGAATAGGGAAAAAAACAGCAGAGAAGTTGATGGTTGATCTTAAACAAAAGCTTC
CTGCTTTGATGCCACTTTATTTAGAGGAGCCTGTGGTGGCTTCTTCAAGTACTACTACTTCTTTTAAAGAAGGCATAGGA
GCTTTGATGAATCTTGGATTTTCCCGCCTTGCAGCTGATCGCATGATGACTGAAGCTGTAAAGGAATTATCTGAAGATGC
TTCGGTGGCAGAACTTCTTCCTGTAGCTCTAAGAAAAGGCTAG

Upstream 100 bases:

>100_bases
GATATTGCGGATGCTTTTGCTTTAGCCATGTGTCATGCACATTTAGCGCCTTATCAGGATCTAAAAAAAAGTCTTTTGTA
ATCGATGGAATTAGACTCCA

Downstream 100 bases:

>100_bases
AATCCCCAGATGCCTTCTCGGGTATTTCTGAAAAATCTCAGCTAAGTTATAGTCTTCTTAAAATTGTGTTGTAAAACAAC
CTCTTTTTCATTTCTAGCGA

Product: Holliday junction DNA helicase RuvA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 200; Mature: 200

Protein sequence:

>200_residues
MYEYIKGKLTHTDEAYVVIESFGIGYSIMLSERFLVDLRELMHQEVLIYVHSVIRETEHSLYGFSSRAERECFRLLISFS
GIGPKTGLAILNMFPLQELCSVARLENVKAIASVPGIGKKTAEKLMVDLKQKLPALMPLYLEEPVVASSSTTTSFKEGIG
ALMNLGFSRLAADRMMTEAVKELSEDASVAELLPVALRKG

Sequences:

>Translated_200_residues
MYEYIKGKLTHTDEAYVVIESFGIGYSIMLSERFLVDLRELMHQEVLIYVHSVIRETEHSLYGFSSRAERECFRLLISFS
GIGPKTGLAILNMFPLQELCSVARLENVKAIASVPGIGKKTAEKLMVDLKQKLPALMPLYLEEPVVASSSTTTSFKEGIG
ALMNLGFSRLAADRMMTEAVKELSEDASVAELLPVALRKG
>Mature_200_residues
MYEYIKGKLTHTDEAYVVIESFGIGYSIMLSERFLVDLRELMHQEVLIYVHSVIRETEHSLYGFSSRAERECFRLLISFS
GIGPKTGLAILNMFPLQELCSVARLENVKAIASVPGIGKKTAEKLMVDLKQKLPALMPLYLEEPVVASSSTTTSFKEGIG
ALMNLGFSRLAADRMMTEAVKELSEDASVAELLPVALRKG

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG0632

COG function: function code L; Holliday junction resolvasome, DNA-binding subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvA family

Homologues:

Organism=Escherichia coli, GI1788168, Length=206, Percent_Identity=34.4660194174757, Blast_Score=111, Evalue=3e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RUVA_CHLMU (Q9PJP0)

Other databases:

- EMBL:   AE002160
- PIR:   D81662
- RefSeq:   NP_297161.1
- ProteinModelPortal:   Q9PJP0
- SMR:   Q9PJP0
- GeneID:   1246154
- GenomeReviews:   AE002160_GR
- KEGG:   cmu:TC0788
- TIGR:   TC_0788
- HOGENOM:   HBG635309
- OMA:   YKTAMSI
- PhylomeDB:   Q9PJP0
- ProtClustDB:   PRK00116
- BioCyc:   CMUR243161:TC_0788-MONOMER
- HAMAP:   MF_00031
- InterPro:   IPR011114
- InterPro:   IPR013849
- InterPro:   IPR003583
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR000085
- InterPro:   IPR010994
- Gene3D:   G3DSA:2.40.50.140
- SMART:   SM00278
- TIGRFAMs:   TIGR00084

Pfam domain/function: PF07499 RuvA_C; PF01330 RuvA_N; SSF50249 Nucleic_acid_OB; SSF47781 RuvA_2_like

EC number: =3.6.4.12

Molecular weight: Translated: 22194; Mature: 22194

Theoretical pI: Translated: 6.14; Mature: 6.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYEYIKGKLTHTDEAYVVIESFGIGYSIMLSERFLVDLRELMHQEVLIYVHSVIRETEHS
CCCCCCCCCCCCCCEEEEEEECCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LYGFSSRAERECFRLLISFSGIGPKTGLAILNMFPLQELCSVARLENVKAIASVPGIGKK
HHCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCHH
TAEKLMVDLKQKLPALMPLYLEEPVVASSSTTTSFKEGIGALMNLGFSRLAADRMMTEAV
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KELSEDASVAELLPVALRKG
HHHHCCCHHHHHHHHHHCCC
>Mature Secondary Structure
MYEYIKGKLTHTDEAYVVIESFGIGYSIMLSERFLVDLRELMHQEVLIYVHSVIRETEHS
CCCCCCCCCCCCCCEEEEEEECCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LYGFSSRAERECFRLLISFSGIGPKTGLAILNMFPLQELCSVARLENVKAIASVPGIGKK
HHCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCHH
TAEKLMVDLKQKLPALMPLYLEEPVVASSSTTTSFKEGIGALMNLGFSRLAADRMMTEAV
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KELSEDASVAELLPVALRKG
HHHHCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10684935