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The map label for this gene is tlc-2

Identifier: 15835396

GI number: 15835396

Start: 924755

End: 926386

Strand: Reverse

Name: tlc-2

Synonym: TC0782

Alternate gene names: 15835396

Gene position: 926386-924755 (Counterclockwise)

Preceding gene: 15835397

Following gene: 15835395

Centisome position: 86.34

GC content: 43.57

Gene sequence:

>1632_bases
ATGTCTTCCGAGGTAAAAACCTTTTCGAAGTTTAGAAGATACTTTTTCCCTATCCACAAATCAGAATTCCCCAAATTCAT
ACCGCTGCTTTTGTTAGCTTTTTTTGTAGGTTTTAACTACTCATTACTAAAGACCACAAAAGATTCTCTTGTTTTAGCCG
GGTCTCGAGCAGGAGCGGAAGTTATACCCTTCTTAAAAGTCTGGGGGATTGTTCCAGGTGCTGTTATTATCACCATGATT
TATGGGTGGATGAGTTGTCGTTACTCCAGAGGCTTCGTTTTCTGCGCTCTTGTTGGTGGTTTTTTGAGCTTTTTTGCTCT
ATTTGCTTGCGTGATTTACCCTATGGGGGATGCGTTGCATTTGAACGGATTGGCCGCAAAACTGCAGACTATTCTGCCTC
GAGGAGCTCGAGGTTTCGTAGTTATGGTTCAGTACTGGAGCTACAGCTTGTACTACGTAATGTCTGAGCTATGGAGTTCC
GTTGTTTTATCCACTTTATTTTGGGGGATCGCTAACCACATTACGAGTGTGCGTGAAGCAGGCCGCTTTTACGCTCTCAT
TAATGTTGGATTAAATGTCTCTTCTATTGTTGCGGGAGAAATTTCTCTCTGGCTGGGTAAACATACGTTAATTCCTTCCT
CTATGGCTGTGGATGCTTGGCACGGGGTATTACTCAATATTACTCTGTTGATTGTTGCTGCAGGAGGATTGATCCTCTAT
TTATACCGAAAACTGGACCATTTAACAGAAGAGGCTCCTGTATTAGGAGACGGATTGGTGTCAGAAATGTCGGTTGCTCA
GCTCAAGCAGGAGAAGAAGCGGCCTAAGGCAAAAGCAAAAAGTCTTCTGTCTGTTCTGTTCCGTTCCCGCTATTTAATGG
GAATTGCTGTTGTTGTTCTCGCTTACAACTTAGCTATCCATCTGTTAGAAGTTGTTTGGAAGGAGCAAGTCTGTCAAATC
TATTCCTCTCGAGTAGAATTTAATTCCTACATGAGTAGGATTACAGCTTTCACTGGGATAGTGTCTGCTCTGGCAGGGGT
TTTTGCTGCAGGGCAAAGTATCCGCCGGTGGGGGTGGACTGTTGGAGCTTTGATAACTCCGCTAACGATGTTGATAACGG
GGGGGCTCTTCTTTGGTGCGATCTATGCTGTAAAAGGCGATGCGATGATTTTAGGCGGATTTCTTGGATTTTCCCCGCTA
GTTCTCACAGCTTGGCTGGGAGGTGTGCAGAACGTCTTTTCTAGAGCAATTAAATTTACTTACTTTGATCAAACTAAAGA
AATGGCATTTATTCCTTTGGAAGATGATGAGAAAGATTATGGTAAGGCCGCTATTGATGGAGTGATTTCTAGGGTTGGTA
AGTCGGGGGGATCTTTGGTTTACCAAGCATTATTGATCATTTTCTCTTCTGTTGCAGATTGCATGAATGCGATTACTATT
GTCTTACTATTAGCTTTAGGAGGATGGATTTGGGTAGTTGCTTGGTTAGGTAAAGAGTATTCTGTTAGAACCGCTGCTTT
AGGTAAGGCGAGGGCTGCTGAAGAGCCGTCTTTGCAGGATGAAGACGAGAGTAGAGTCTCCTCTCCTATATCAGAGCCCG
AAGCTCGAGAAGAGGTAGTAACAACTTTATAG

Upstream 100 bases:

>100_bases
CGTTCAGCAATTGTTGTTCTAAAATTCAAAAAAACGCGAGTTTCTTCGCGTTAAAAAATTTTCTCCAAAAATCTTTAATA
TTTAAATTGGGAAGGAATGT

Downstream 100 bases:

>100_bases
TTTGACTAAGAAAAAGACCTGGGAAAGAACATCCCAGGTCTTTTAGGTTTTTTTGCTTAAAAATTCTTTTTATAATCCTC
ATGTTTTAGTACCGTTTTAT

Product: ADP, ATP carrier protein

Products: NA

Alternate protein names: ADP/ATP translocase 2

Number of amino acids: Translated: 543; Mature: 542

Protein sequence:

>543_residues
MSSEVKTFSKFRRYFFPIHKSEFPKFIPLLLLAFFVGFNYSLLKTTKDSLVLAGSRAGAEVIPFLKVWGIVPGAVIITMI
YGWMSCRYSRGFVFCALVGGFLSFFALFACVIYPMGDALHLNGLAAKLQTILPRGARGFVVMVQYWSYSLYYVMSELWSS
VVLSTLFWGIANHITSVREAGRFYALINVGLNVSSIVAGEISLWLGKHTLIPSSMAVDAWHGVLLNITLLIVAAGGLILY
LYRKLDHLTEEAPVLGDGLVSEMSVAQLKQEKKRPKAKAKSLLSVLFRSRYLMGIAVVVLAYNLAIHLLEVVWKEQVCQI
YSSRVEFNSYMSRITAFTGIVSALAGVFAAGQSIRRWGWTVGALITPLTMLITGGLFFGAIYAVKGDAMILGGFLGFSPL
VLTAWLGGVQNVFSRAIKFTYFDQTKEMAFIPLEDDEKDYGKAAIDGVISRVGKSGGSLVYQALLIIFSSVADCMNAITI
VLLLALGGWIWVVAWLGKEYSVRTAALGKARAAEEPSLQDEDESRVSSPISEPEAREEVVTTL

Sequences:

>Translated_543_residues
MSSEVKTFSKFRRYFFPIHKSEFPKFIPLLLLAFFVGFNYSLLKTTKDSLVLAGSRAGAEVIPFLKVWGIVPGAVIITMI
YGWMSCRYSRGFVFCALVGGFLSFFALFACVIYPMGDALHLNGLAAKLQTILPRGARGFVVMVQYWSYSLYYVMSELWSS
VVLSTLFWGIANHITSVREAGRFYALINVGLNVSSIVAGEISLWLGKHTLIPSSMAVDAWHGVLLNITLLIVAAGGLILY
LYRKLDHLTEEAPVLGDGLVSEMSVAQLKQEKKRPKAKAKSLLSVLFRSRYLMGIAVVVLAYNLAIHLLEVVWKEQVCQI
YSSRVEFNSYMSRITAFTGIVSALAGVFAAGQSIRRWGWTVGALITPLTMLITGGLFFGAIYAVKGDAMILGGFLGFSPL
VLTAWLGGVQNVFSRAIKFTYFDQTKEMAFIPLEDDEKDYGKAAIDGVISRVGKSGGSLVYQALLIIFSSVADCMNAITI
VLLLALGGWIWVVAWLGKEYSVRTAALGKARAAEEPSLQDEDESRVSSPISEPEAREEVVTTL
>Mature_542_residues
SSEVKTFSKFRRYFFPIHKSEFPKFIPLLLLAFFVGFNYSLLKTTKDSLVLAGSRAGAEVIPFLKVWGIVPGAVIITMIY
GWMSCRYSRGFVFCALVGGFLSFFALFACVIYPMGDALHLNGLAAKLQTILPRGARGFVVMVQYWSYSLYYVMSELWSSV
VLSTLFWGIANHITSVREAGRFYALINVGLNVSSIVAGEISLWLGKHTLIPSSMAVDAWHGVLLNITLLIVAAGGLILYL
YRKLDHLTEEAPVLGDGLVSEMSVAQLKQEKKRPKAKAKSLLSVLFRSRYLMGIAVVVLAYNLAIHLLEVVWKEQVCQIY
SSRVEFNSYMSRITAFTGIVSALAGVFAAGQSIRRWGWTVGALITPLTMLITGGLFFGAIYAVKGDAMILGGFLGFSPLV
LTAWLGGVQNVFSRAIKFTYFDQTKEMAFIPLEDDEKDYGKAAIDGVISRVGKSGGSLVYQALLIIFSSVADCMNAITIV
LLLALGGWIWVVAWLGKEYSVRTAALGKARAAEEPSLQDEDESRVSSPISEPEAREEVVTTL

Specific function: Unknown

COG id: COG3202

COG function: function code C; ATP/ADP translocase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ADP/ATP translocase tlc family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): TLC2_CHLMU (Q9PJP6)

Other databases:

- EMBL:   AE002160
- PIR:   F81665
- RefSeq:   NP_297155.1
- GeneID:   1246147
- GenomeReviews:   AE002160_GR
- KEGG:   cmu:TC0782
- TIGR:   TC_0782
- HOGENOM:   HBG586333
- OMA:   AFFVGFN
- ProtClustDB:   CLSK870724
- BioCyc:   CMUR243161:TC_0782-MONOMER
- InterPro:   IPR004667
- TIGRFAMs:   TIGR00769

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 59673; Mature: 59542

Theoretical pI: Translated: 9.32; Mature: 9.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xd604ad0)-; HASH(0x946cbb4)-; HASH(0xd5dca24)-; HASH(0xc328278)-; HASH(0xc68bd24)-; HASH(0xd3574d0)-; HASH(0xc923650)-; HASH(0xd875860)-; HASH(0xcf924a0)-; HASH(0xcccaed8)-; HASH(0xd70f65c)-; HASH(0xd74faac)-;

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSEVKTFSKFRRYFFPIHKSEFPKFIPLLLLAFFVGFNYSLLKTTKDSLVLAGSRAGAE
CCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCHHHHCCCCCEEEECCCCCCH
VIPFLKVWGIVPGAVIITMIYGWMSCRYSRGFVFCALVGGFLSFFALFACVIYPMGDALH
HHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
LNGLAAKLQTILPRGARGFVVMVQYWSYSLYYVMSELWSSVVLSTLFWGIANHITSVREA
HHHHHHHHHHHCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GRFYALINVGLNVSSIVAGEISLWLGKHTLIPSSMAVDAWHGVLLNITLLIVAAGGLILY
CCEEEEEEECCCHHHHHHHHHHHHHCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LYRKLDHLTEEAPVLGDGLVSEMSVAQLKQEKKRPKAKAKSLLSVLFRSRYLMGIAVVVL
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
AYNLAIHLLEVVWKEQVCQIYSSRVEFNSYMSRITAFTGIVSALAGVFAAGQSIRRWGWT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VGALITPLTMLITGGLFFGAIYAVKGDAMILGGFLGFSPLVLTAWLGGVQNVFSRAIKFT
HHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YFDQTKEMAFIPLEDDEKDYGKAAIDGVISRVGKSGGSLVYQALLIIFSSVADCMNAITI
EECCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
VLLLALGGWIWVVAWLGKEYSVRTAALGKARAAEEPSLQDEDESRVSSPISEPEAREEVV
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHCCCCCCCHHHHHHH
TTL
HCH
>Mature Secondary Structure 
SSEVKTFSKFRRYFFPIHKSEFPKFIPLLLLAFFVGFNYSLLKTTKDSLVLAGSRAGAE
CCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCHHHHCCCCCEEEECCCCCCH
VIPFLKVWGIVPGAVIITMIYGWMSCRYSRGFVFCALVGGFLSFFALFACVIYPMGDALH
HHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
LNGLAAKLQTILPRGARGFVVMVQYWSYSLYYVMSELWSSVVLSTLFWGIANHITSVREA
HHHHHHHHHHHCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GRFYALINVGLNVSSIVAGEISLWLGKHTLIPSSMAVDAWHGVLLNITLLIVAAGGLILY
CCEEEEEEECCCHHHHHHHHHHHHHCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LYRKLDHLTEEAPVLGDGLVSEMSVAQLKQEKKRPKAKAKSLLSVLFRSRYLMGIAVVVL
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
AYNLAIHLLEVVWKEQVCQIYSSRVEFNSYMSRITAFTGIVSALAGVFAAGQSIRRWGWT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VGALITPLTMLITGGLFFGAIYAVKGDAMILGGFLGFSPLVLTAWLGGVQNVFSRAIKFT
HHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YFDQTKEMAFIPLEDDEKDYGKAAIDGVISRVGKSGGSLVYQALLIIFSSVADCMNAITI
EECCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
VLLLALGGWIWVVAWLGKEYSVRTAALGKARAAEEPSLQDEDESRVSSPISEPEAREEVV
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHCCCCCCCHHHHHHH
TTL
HCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10684935