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The map label for this gene is coaE

Identifier: 15835393

GI number: 15835393

Start: 920399

End: 921016

Strand: Reverse

Name: coaE

Synonym: TC0779

Alternate gene names: 15835393

Gene position: 921016-920399 (Counterclockwise)

Preceding gene: 15835394

Following gene: 15835392

Centisome position: 85.84

GC content: 40.13

Gene sequence:

>618_bases
TTGGGCGGAATGCTAGATTTATTGAAGATTTCTGTTACAGGGGATCCCTCTTCGGGGAAAACTGAGGCGTGTCAGGTTTT
TGAAGAATTGGGGGCTTTTGTAATTAGTGCTGATAAAGTTTCTCATAGTTTCCTTGTTCCTTATACCTCAGAGGGTCAGC
GTGTAGTTGATCTTTTGGGTCCAGAGATAATCGTAGAGAATACTCTCAATAGAAAGGCTATCGCTAAAAAAGTTTTTGGT
AACCGAGATTTGTTGCTGTCCTTAGAAAAGATCTTGCATCCGGGAGTATGCCGTTTTGTTGAGGAAAACTATACGCAAGT
GGTTCAAGCACAAAAATATTCTCTGTTTGTTGTAGAAGTCCCTCTGTTGTATGAGATTCAGTATGCAGATTGGTTTGATC
GGGTTATTTTGATCTCTGCAGATACCGAGATACGTAAAGAGCGTTTTCTTAAAAAAACTGGAGGCTCGGATACCAGTTTC
GATCTTCGGTGTGCGCGCTTTTCTTCTTTAGAAGAAAAAATTCTGCGAGCGGATGTGGTCATAGAGAACAATGGAACGAA
GGAAGAATTTCGTCACAAAGTAAAACAATGTTTTAAGGCTTTAAAGGGAACAATATGA

Upstream 100 bases:

>100_bases
AGGAAGAATTAGAGGAGATGAAAGTCCTTGTTCAAGAGAAGATGGAGTCCGCAATGTCGCTGTCTGTTCCTTTGGTTGTG
AATGTCTTAATTGGAAAAAA

Downstream 100 bases:

>100_bases
AAGAAGAAAGTCCAGCCGAGGTCTTACACAAGGTAAAGGAGCATAAGAGGCGCGAGGGTCCTTTACCATTGGGAAAAGAA
GGTAGTGAAGACAGTGCTGT

Product: dephospho-CoA kinase

Products: NA

Alternate protein names: Dephosphocoenzyme A kinase [H]

Number of amino acids: Translated: 205; Mature: 204

Protein sequence:

>205_residues
MGGMLDLLKISVTGDPSSGKTEACQVFEELGAFVISADKVSHSFLVPYTSEGQRVVDLLGPEIIVENTLNRKAIAKKVFG
NRDLLLSLEKILHPGVCRFVEENYTQVVQAQKYSLFVVEVPLLYEIQYADWFDRVILISADTEIRKERFLKKTGGSDTSF
DLRCARFSSLEEKILRADVVIENNGTKEEFRHKVKQCFKALKGTI

Sequences:

>Translated_205_residues
MGGMLDLLKISVTGDPSSGKTEACQVFEELGAFVISADKVSHSFLVPYTSEGQRVVDLLGPEIIVENTLNRKAIAKKVFG
NRDLLLSLEKILHPGVCRFVEENYTQVVQAQKYSLFVVEVPLLYEIQYADWFDRVILISADTEIRKERFLKKTGGSDTSF
DLRCARFSSLEEKILRADVVIENNGTKEEFRHKVKQCFKALKGTI
>Mature_204_residues
GGMLDLLKISVTGDPSSGKTEACQVFEELGAFVISADKVSHSFLVPYTSEGQRVVDLLGPEIIVENTLNRKAIAKKVFGN
RDLLLSLEKILHPGVCRFVEENYTQVVQAQKYSLFVVEVPLLYEIQYADWFDRVILISADTEIRKERFLKKTGGSDTSFD
LRCARFSSLEEKILRADVVIENNGTKEEFRHKVKQCFKALKGTI

Specific function: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A [H]

COG id: COG0237

COG function: function code H; Dephospho-CoA kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DPCK (dephospho-CoA kinase) domain [H]

Homologues:

Organism=Homo sapiens, GI191252797, Length=179, Percent_Identity=24.5810055865922, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI191252795, Length=179, Percent_Identity=24.5810055865922, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI110227607, Length=198, Percent_Identity=25.7575757575758, Blast_Score=65, Evalue=5e-11,
Organism=Escherichia coli, GI1786292, Length=189, Percent_Identity=25.9259259259259, Blast_Score=65, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17554944, Length=201, Percent_Identity=29.8507462686567, Blast_Score=90, Evalue=6e-19,
Organism=Drosophila melanogaster, GI24644728, Length=184, Percent_Identity=27.1739130434783, Blast_Score=81, Evalue=6e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001977 [H]

Pfam domain/function: PF01121 CoaE [H]

EC number: =2.7.1.24 [H]

Molecular weight: Translated: 23124; Mature: 22993

Theoretical pI: Translated: 6.78; Mature: 6.78

Prosite motif: PS01294 COAE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGGMLDLLKISVTGDPSSGKTEACQVFEELGAFVISADKVSHSFLVPYTSEGQRVVDLLG
CCCCEEEEEEEEECCCCCCHHHHHHHHHHHCCEEEECCCCCCEEEEEECCCCCEEHHHHC
PEIIVENTLNRKAIAKKVFGNRDLLLSLEKILHPGVCRFVEENYTQVVQAQKYSLFVVEV
CCEEEECCCCHHHHHHHHHCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCEEEEEEEE
PLLYEIQYADWFDRVILISADTEIRKERFLKKTGGSDTSFDLRCARFSSLEEKILRADVV
CEEEEEECCCCCCEEEEEECCCHHHHHHHHHHCCCCCCCCEEHHHHHHHHHHHHHHHHEE
IENNGTKEEFRHKVKQCFKALKGTI
EECCCCHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
GGMLDLLKISVTGDPSSGKTEACQVFEELGAFVISADKVSHSFLVPYTSEGQRVVDLLG
CCCEEEEEEEEECCCCCCHHHHHHHHHHHCCEEEECCCCCCEEEEEECCCCCEEHHHHC
PEIIVENTLNRKAIAKKVFGNRDLLLSLEKILHPGVCRFVEENYTQVVQAQKYSLFVVEV
CCEEEECCCCHHHHHHHHHCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCEEEEEEEE
PLLYEIQYADWFDRVILISADTEIRKERFLKKTGGSDTSFDLRCARFSSLEEKILRADVV
CEEEEEECCCCCCEEEEEECCCHHHHHHHHHHCCCCCCCCEEHHHHHHHHHHHHHHHHEE
IENNGTKEEFRHKVKQCFKALKGTI
EECCCCHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10684935 [H]