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The map label for this gene is nrdR

Identifier: 15835301

GI number: 15835301

Start: 818797

End: 819255

Strand: Direct

Name: nrdR

Synonym: TC0686

Alternate gene names: 15835301

Gene position: 818797-819255 (Clockwise)

Preceding gene: 15835292

Following gene: 15835302

Centisome position: 76.31

GC content: 39.22

Gene sequence:

>459_bases
ATGCTATGCCCATTTTGTAACCATGGAGAGCTTAAAGTTATTGACTCTCGAAACTCCCCTGAGGCGAACGCAATTAAACG
CCGCCGCGAATGTTTACGATGTAGTCAAAGATTCACCACCTTTGAAACTGTCGAATTAACGATACAGGTGTTAAAACGGG
ATGGTCGCTATGAAAACTTCCAAGAAGCTAAGCTGATAAATGGACTTAAAGCTGCTTCCAGTCACACAAGAATCGGGCAA
GAACAAGTACAAGCTATAGCCTCCAATATCAAACAAGATCTACTTGGAAAACAAAATCGAGAAATTTCTACCAAAGAAAT
AGGTGAACTAGTAATGAAATATCTAAAAAAAGCAGATATGATTGCGTACATTAGGTTCGCCTGCGTTTATAGAAGATTTA
GAGATGTAGGAGAGCTCATGGAAGTTTTATTATCTGCAACCCCAGACGGTGAAAAATAA

Upstream 100 bases:

>100_bases
AATTGTGTTACCAGATCCACTAAACTACATCTTTCATTTCTGAAGGACCTTTCAGTAGTCAATAAGGATCCAATGTTTGA
ATTTTTAGGAGGAATCTCCC

Downstream 100 bases:

>100_bases
ATACGAAAAGGAGAATTTTATGCCCCTAACGGACGAAGAAATAGCCGATTTTAAAACACGTCTTCTAGAAATGAAGGCAA
AATTGTCTCATACTTTAGAA

Product: transcriptional regulator NrdR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 152; Mature: 152

Protein sequence:

>152_residues
MLCPFCNHGELKVIDSRNSPEANAIKRRRECLRCSQRFTTFETVELTIQVLKRDGRYENFQEAKLINGLKAASSHTRIGQ
EQVQAIASNIKQDLLGKQNREISTKEIGELVMKYLKKADMIAYIRFACVYRRFRDVGELMEVLLSATPDGEK

Sequences:

>Translated_152_residues
MLCPFCNHGELKVIDSRNSPEANAIKRRRECLRCSQRFTTFETVELTIQVLKRDGRYENFQEAKLINGLKAASSHTRIGQ
EQVQAIASNIKQDLLGKQNREISTKEIGELVMKYLKKADMIAYIRFACVYRRFRDVGELMEVLLSATPDGEK
>Mature_152_residues
MLCPFCNHGELKVIDSRNSPEANAIKRRRECLRCSQRFTTFETVELTIQVLKRDGRYENFQEAKLINGLKAASSHTRIGQ
EQVQAIASNIKQDLLGKQNREISTKEIGELVMKYLKKADMIAYIRFACVYRRFRDVGELMEVLLSATPDGEK

Specific function: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes [H]

COG id: COG1327

COG function: function code K; Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-cone domain [H]

Homologues:

Organism=Escherichia coli, GI1786615, Length=142, Percent_Identity=45.0704225352113, Blast_Score=119, Evalue=7e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005144
- InterPro:   IPR003796 [H]

Pfam domain/function: PF03477 ATP-cone [H]

EC number: NA

Molecular weight: Translated: 17471; Mature: 17471

Theoretical pI: Translated: 9.28; Mature: 9.28

Prosite motif: PS51161 ATP_CONE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
3.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLCPFCNHGELKVIDSRNSPEANAIKRRRECLRCSQRFTTFETVELTIQVLKRDGRYENF
CCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCH
QEAKLINGLKAASSHTRIGQEQVQAIASNIKQDLLGKQNREISTKEIGELVMKYLKKADM
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHH
IAYIRFACVYRRFRDVGELMEVLLSATPDGEK
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MLCPFCNHGELKVIDSRNSPEANAIKRRRECLRCSQRFTTFETVELTIQVLKRDGRYENF
CCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCH
QEAKLINGLKAASSHTRIGQEQVQAIASNIKQDLLGKQNREISTKEIGELVMKYLKKADM
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHH
IAYIRFACVYRRFRDVGELMEVLLSATPDGEK
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA