Click here to switch to the map view.

The map label for this gene is Not Available

Identifier: 15835291

GI number: 15835291

Start: 807745

End: 809823

Strand: Direct

Name: Not Available

Synonym: TC0676

Alternate gene names: 15835291

Gene position: 807745-809823 (Clockwise)

Preceding gene: 15835290

Following gene: 15835292

Centisome position: 75.28

GC content: 40.6

Gene sequence:

>2079_bases
GTGGGAAAAGCTAAAAACAAAAAGAAAGTTCTAAAAAATAAACAGCAGGTTCTGGTTCCTGGTATTTTATTCGTTCATCC
TAAAAAAGGGTTCGGATTCGTTTCTCCAGATCAACCAGATCTATACCCCTTTGATATTTTTGTCCCGGCCAGTGATTTAA
AAGGCGCTTTAGATGGGGATCATGTTCTTGTTGCTCTCCCCTTCTCCCAGCGTGGAGGGGAAAAAAGAAAAGGAGTGATT
CATAAAGTTCTTTCTCGTGGGAAAACTGTCTTAGTAGGAACTATCATCTCCCTTATCAGCCCAACCTTGGCAATGGTTTG
TGTTAATGCTATCAGTCCCGAAGTTCCTTTAAAAGCAGAGCTTCTTCCTAAAAGGACATATAAGATCGGAGATCGTCTAT
TACTCAAAACTCCCGGATGGAAAGAAAATTACCCAAGTAAAGAGCCTCCTCCCCTAGCTATGTTAGAATTCATGGGGAAT
ATCTCTAATGCAAAAACAGATTTTCCTGTCATTAAGGCTGAATTTTCCATTACAGAAGAGTTCCCTGAAGCTGTTGTTCA
AGAAGCTAGTCAGTTCTTGCAAAAACACGTTACACAAGCTTTACACTCCAGAAAAGATCTTCGCGATCTTTTATGCTTTA
CCATAGACTCTGCTTCGGCTAAAGACTTCGATGATGCCGTTTCGCTAACTTATGATCATGAAGGGAATTATATTTTAGGC
GTTCATATCGCTGATGTTTCTCACTATGTTACTCCGAATTCGGCCCTAGATCAAGAGGCTGCTAAACGATGCAATTCCAT
CTATTTCCCAGGGAAAGTAATTCCTATGCTTCCCTCAGCTCTTTCTGATAATTTGTGCAGTTTAAAACCCAATGTGGATC
GTCTAGCGGTGTCCGTGTTTATGACTTTTTCCAAGGAAGGGTTCCTCTCAGATTACAGAATTTTGCGTAGTGTTATCCGC
AGTAAATACCGAATGACTTACGATGAAGTAGATGAAATTATCGAGAAGAAATTAGCTCACCCTATTTCTAAAACCATTTT
AGAGATGGCTGAGCTGAGCCGTATTTTTTCCGATATCCGCGAACAACGTGGCTGCACACGTCTCGTGCTTCCCTCTTTCA
CAATGTCTCTTGATAATTTACAAGAACCTGTAGCCCTTGTCGAAAACAAACAAACTGCTGCCCATAAACTCATTGAAGAA
TTTATGCTGAAAGCTAATGAGGTGATCGCTTATCACATTTCTCATCAGGGAATCACTATGCCTTTCCGCATACATGAGCC
CCCGAATGAAGAGAATCTTCTTCTTTTTAGAGAAACTGCGAAAGCTATGGGCTTCACTATCACACAAACTCCTACACAAG
AGCCCGATTACCAATATTTGTTACAAGAAACCTCTGCTGGACACCCTCTGGAGCCTATTCTTCATTCCCAGTTTGTGCGC
AGCATGAAGACCGCTTCTTATTCTACAGAAAACAAAGGTCATTATGGTCTTTGTTTGGATTACTATACGCATTTTACTAG
CCCGATTCGTCGATATGTGGATCTTATTGTTCACAGGCTTCTTTTCCATCCGCTTTCTGTAGAAGAAGGACATCTTGAAC
AAATTGTTCGAGCCTGTTCATCTCAGGAACGTGTTGCAGCAAAAGCTGAAGGAGCTTTTATAAATATAAAAAAAGCTCGC
TTTTTGAAAAAATTCCTTGATGAGCAGCCTGCAACACTTTACAAAGCTTTCATCATTACAGTATCTCCGGAAGGGCTCTC
TTTCGTTCTTCCTGAATTGTGTCATGAAGGGTTCATCCCCGCTGCTAAGCTTCCCAAGAAATATGTCATAAAAACAAAGC
TTGGATTGGAAGAGCTTCCTGAACATTTGCTCCCAGGAATACCTATTTCGGTACAACTTGCTTCCGTTACCTTACTTACA
CAGGCTATTGAATGGACTTTGATTGAATCTAAAGAGAGAAGCTCCTCGAAAAAAAAGAAAGCAAAAGCAAAATCCAATGC
AACGCAAGTGAAGAAAAAGAGTTCTTCTAAAAAGAAGAAAGCGGTCTCCAAAGCTAAAAAAAATCGAGGAGGAAAATAG

Upstream 100 bases:

>100_bases
ACCGACTGCCCTAATACCTCTAGCTTCAAGATGCAAAACATTTTTAGAGGTTTGAGAAGCAAGACTGTACAGGCAGTACG
ACAGCAATGGAGTTTAGCTT

Downstream 100 bases:

>100_bases
CCCTATTACTCCCTCTCTTTCAAGAAATTCTTTACAAGATTGACTTTCTTCTTTTGAAAAAGGTTTTCTTAAACAAAACG
TGCTTTACTTCTTGCAGAAA

Product: VacB/Rnb family exoribonuclease

Products: NA

Alternate protein names: RNase R; VacB protein homolog

Number of amino acids: Translated: 692; Mature: 691

Protein sequence:

>692_residues
MGKAKNKKKVLKNKQQVLVPGILFVHPKKGFGFVSPDQPDLYPFDIFVPASDLKGALDGDHVLVALPFSQRGGEKRKGVI
HKVLSRGKTVLVGTIISLISPTLAMVCVNAISPEVPLKAELLPKRTYKIGDRLLLKTPGWKENYPSKEPPPLAMLEFMGN
ISNAKTDFPVIKAEFSITEEFPEAVVQEASQFLQKHVTQALHSRKDLRDLLCFTIDSASAKDFDDAVSLTYDHEGNYILG
VHIADVSHYVTPNSALDQEAAKRCNSIYFPGKVIPMLPSALSDNLCSLKPNVDRLAVSVFMTFSKEGFLSDYRILRSVIR
SKYRMTYDEVDEIIEKKLAHPISKTILEMAELSRIFSDIREQRGCTRLVLPSFTMSLDNLQEPVALVENKQTAAHKLIEE
FMLKANEVIAYHISHQGITMPFRIHEPPNEENLLLFRETAKAMGFTITQTPTQEPDYQYLLQETSAGHPLEPILHSQFVR
SMKTASYSTENKGHYGLCLDYYTHFTSPIRRYVDLIVHRLLFHPLSVEEGHLEQIVRACSSQERVAAKAEGAFINIKKAR
FLKKFLDEQPATLYKAFIITVSPEGLSFVLPELCHEGFIPAAKLPKKYVIKTKLGLEELPEHLLPGIPISVQLASVTLLT
QAIEWTLIESKERSSSKKKKAKAKSNATQVKKKSSSKKKKAVSKAKKNRGGK

Sequences:

>Translated_692_residues
MGKAKNKKKVLKNKQQVLVPGILFVHPKKGFGFVSPDQPDLYPFDIFVPASDLKGALDGDHVLVALPFSQRGGEKRKGVI
HKVLSRGKTVLVGTIISLISPTLAMVCVNAISPEVPLKAELLPKRTYKIGDRLLLKTPGWKENYPSKEPPPLAMLEFMGN
ISNAKTDFPVIKAEFSITEEFPEAVVQEASQFLQKHVTQALHSRKDLRDLLCFTIDSASAKDFDDAVSLTYDHEGNYILG
VHIADVSHYVTPNSALDQEAAKRCNSIYFPGKVIPMLPSALSDNLCSLKPNVDRLAVSVFMTFSKEGFLSDYRILRSVIR
SKYRMTYDEVDEIIEKKLAHPISKTILEMAELSRIFSDIREQRGCTRLVLPSFTMSLDNLQEPVALVENKQTAAHKLIEE
FMLKANEVIAYHISHQGITMPFRIHEPPNEENLLLFRETAKAMGFTITQTPTQEPDYQYLLQETSAGHPLEPILHSQFVR
SMKTASYSTENKGHYGLCLDYYTHFTSPIRRYVDLIVHRLLFHPLSVEEGHLEQIVRACSSQERVAAKAEGAFINIKKAR
FLKKFLDEQPATLYKAFIITVSPEGLSFVLPELCHEGFIPAAKLPKKYVIKTKLGLEELPEHLLPGIPISVQLASVTLLT
QAIEWTLIESKERSSSKKKKAKAKSNATQVKKKSSSKKKKAVSKAKKNRGGK
>Mature_691_residues
GKAKNKKKVLKNKQQVLVPGILFVHPKKGFGFVSPDQPDLYPFDIFVPASDLKGALDGDHVLVALPFSQRGGEKRKGVIH
KVLSRGKTVLVGTIISLISPTLAMVCVNAISPEVPLKAELLPKRTYKIGDRLLLKTPGWKENYPSKEPPPLAMLEFMGNI
SNAKTDFPVIKAEFSITEEFPEAVVQEASQFLQKHVTQALHSRKDLRDLLCFTIDSASAKDFDDAVSLTYDHEGNYILGV
HIADVSHYVTPNSALDQEAAKRCNSIYFPGKVIPMLPSALSDNLCSLKPNVDRLAVSVFMTFSKEGFLSDYRILRSVIRS
KYRMTYDEVDEIIEKKLAHPISKTILEMAELSRIFSDIREQRGCTRLVLPSFTMSLDNLQEPVALVENKQTAAHKLIEEF
MLKANEVIAYHISHQGITMPFRIHEPPNEENLLLFRETAKAMGFTITQTPTQEPDYQYLLQETSAGHPLEPILHSQFVRS
MKTASYSTENKGHYGLCLDYYTHFTSPIRRYVDLIVHRLLFHPLSVEEGHLEQIVRACSSQERVAAKAEGAFINIKKARF
LKKFLDEQPATLYKAFIITVSPEGLSFVLPELCHEGFIPAAKLPKKYVIKTKLGLEELPEHLLPGIPISVQLASVTLLTQ
AIEWTLIESKERSSSKKKKAKAKSNATQVKKKSSSKKKKAVSKAKKNRGGK

Specific function: 3'-5'exoribonuclease that participates in an essential cell function. Acts nonspecifically on poly(A), poly(U) and ribosomal RNAs

COG id: COG0557

COG function: function code K; Exoribonuclease R

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 S1 motif domain

Homologues:

Organism=Homo sapiens, GI190014625, Length=546, Percent_Identity=28.9377289377289, Blast_Score=196, Evalue=6e-50,
Organism=Homo sapiens, GI190014623, Length=546, Percent_Identity=28.9377289377289, Blast_Score=196, Evalue=7e-50,
Organism=Homo sapiens, GI219521928, Length=536, Percent_Identity=29.8507462686567, Blast_Score=187, Evalue=4e-47,
Organism=Homo sapiens, GI19115966, Length=537, Percent_Identity=29.608938547486, Blast_Score=187, Evalue=4e-47,
Organism=Homo sapiens, GI134288890, Length=363, Percent_Identity=34.7107438016529, Blast_Score=168, Evalue=1e-41,
Organism=Homo sapiens, GI156105695, Length=420, Percent_Identity=27.6190476190476, Blast_Score=112, Evalue=1e-24,
Organism=Homo sapiens, GI156105693, Length=420, Percent_Identity=27.6190476190476, Blast_Score=112, Evalue=2e-24,
Organism=Escherichia coli, GI87082383, Length=674, Percent_Identity=30.5637982195846, Blast_Score=267, Evalue=2e-72,
Organism=Escherichia coli, GI1787542, Length=592, Percent_Identity=27.5337837837838, Blast_Score=149, Evalue=7e-37,
Organism=Caenorhabditis elegans, GI17553506, Length=389, Percent_Identity=31.6195372750643, Blast_Score=169, Evalue=3e-42,
Organism=Caenorhabditis elegans, GI212645896, Length=414, Percent_Identity=30.1932367149758, Blast_Score=166, Evalue=4e-41,
Organism=Saccharomyces cerevisiae, GI6324552, Length=424, Percent_Identity=31.8396226415094, Blast_Score=179, Evalue=1e-45,
Organism=Saccharomyces cerevisiae, GI6320499, Length=451, Percent_Identity=24.1685144124169, Blast_Score=93, Evalue=1e-19,
Organism=Saccharomyces cerevisiae, GI6323943, Length=428, Percent_Identity=23.3644859813084, Blast_Score=89, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24649634, Length=488, Percent_Identity=29.3032786885246, Blast_Score=178, Evalue=1e-44,
Organism=Drosophila melanogaster, GI19922976, Length=351, Percent_Identity=35.042735042735, Blast_Score=164, Evalue=2e-40,
Organism=Drosophila melanogaster, GI24654597, Length=351, Percent_Identity=35.042735042735, Blast_Score=164, Evalue=2e-40,
Organism=Drosophila melanogaster, GI24654592, Length=351, Percent_Identity=35.042735042735, Blast_Score=163, Evalue=3e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RNR_CHLMU (Q9PK00)

Other databases:

- EMBL:   AE002160
- RefSeq:   NP_297050.1
- ProteinModelPortal:   Q9PK00
- SMR:   Q9PK00
- GeneID:   1246037
- GenomeReviews:   AE002160_GR
- KEGG:   cmu:TC0676
- TIGR:   TC_0676
- HOGENOM:   HBG690243
- OMA:   HESPNDE
- PhylomeDB:   Q9PK00
- ProtClustDB:   CLSK871355
- BioCyc:   CMUR243161:TC_0676-MONOMER
- InterPro:   IPR011129
- InterPro:   IPR022967
- InterPro:   IPR013223
- InterPro:   IPR001900
- InterPro:   IPR022966
- InterPro:   IPR004476
- InterPro:   IPR011805
- PANTHER:   PTHR23355:SF9
- SMART:   SM00357
- SMART:   SM00955
- SMART:   SM00316
- TIGRFAMs:   TIGR00358

Pfam domain/function: PF08206 OB_RNB; PF00773 RNB

EC number: 3.1.-.- [C]

Molecular weight: Translated: 77601; Mature: 77470

Theoretical pI: Translated: 9.74; Mature: 9.74

Prosite motif: PS01175 RIBONUCLEASE_II; PS50126 S1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGKAKNKKKVLKNKQQVLVPGILFVHPKKGFGFVSPDQPDLYPFDIFVPASDLKGALDGD
CCCCCCHHHHHCCCCCEEECCEEEEECCCCCCCCCCCCCCCCEEEEEEEHHHCCCCCCCC
HVLVALPFSQRGGEKRKGVIHKVLSRGKTVLVGTIISLISPTLAMVCVNAISPEVPLKAE
EEEEEECCHHCCCHHHHHHHHHHHHCCCEEHHHHHHHHHHHHHHHHHHHHCCCCCCCHHH
LLPKRTYKIGDRLLLKTPGWKENYPSKEPPPLAMLEFMGNISNAKTDFPVIKAEFSITEE
HCCHHHHHCCCEEEEECCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCEEEEEHHHHHH
FPEAVVQEASQFLQKHVTQALHSRKDLRDLLCFTIDSASAKDFDDAVSLTYDHEGNYILG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCEEEE
VHIADVSHYVTPNSALDQEAAKRCNSIYFPGKVIPMLPSALSDNLCSLKPNVDRLAVSVF
EEEECCHHCCCCCHHHHHHHHHHHCCCCCCCCHHHHCHHHHCCCCCCCCCCHHHHHHHHH
MTFSKEGFLSDYRILRSVIRSKYRMTYDEVDEIIEKKLAHPISKTILEMAELSRIFSDIR
HHHCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EQRGCTRLVLPSFTMSLDNLQEPVALVENKQTAAHKLIEEFMLKANEVIAYHISHQGITM
HHCCCCEEECCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCEEEEEECCCCEEE
PFRIHEPPNEENLLLFRETAKAMGFTITQTPTQEPDYQYLLQETSAGHPLEPILHSQFVR
EEEECCCCCCCCEEEEEEHHHHHCEEEECCCCCCCCHHHHHHHCCCCCCCHHHHHHHHHH
SMKTASYSTENKGHYGLCLDYYTHFTSPIRRYVDLIVHRLLFHPLSVEEGHLEQIVRACS
HHHHHCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHC
SQERVAAKAEGAFINIKKARFLKKFLDEQPATLYKAFIITVSPEGLSFVLPELCHEGFIP
CHHHHHHHCCCCEEEHHHHHHHHHHHCCCCHHEEEEEEEEECCCCHHHHHHHHHHCCCCC
AAKLPKKYVIKTKLGLEELPEHLLPGIPISVQLASVTLLTQAIEWTLIESKERSSSKKKK
HHHCCHHHEEHHHCCHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHEECCHHHHHHHHHH
AKAKSNATQVKKKSSSKKKKAVSKAKKNRGGK
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
GKAKNKKKVLKNKQQVLVPGILFVHPKKGFGFVSPDQPDLYPFDIFVPASDLKGALDGD
CCCCCHHHHHCCCCCEEECCEEEEECCCCCCCCCCCCCCCCEEEEEEEHHHCCCCCCCC
HVLVALPFSQRGGEKRKGVIHKVLSRGKTVLVGTIISLISPTLAMVCVNAISPEVPLKAE
EEEEEECCHHCCCHHHHHHHHHHHHCCCEEHHHHHHHHHHHHHHHHHHHHCCCCCCCHHH
LLPKRTYKIGDRLLLKTPGWKENYPSKEPPPLAMLEFMGNISNAKTDFPVIKAEFSITEE
HCCHHHHHCCCEEEEECCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCEEEEEHHHHHH
FPEAVVQEASQFLQKHVTQALHSRKDLRDLLCFTIDSASAKDFDDAVSLTYDHEGNYILG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCEEEE
VHIADVSHYVTPNSALDQEAAKRCNSIYFPGKVIPMLPSALSDNLCSLKPNVDRLAVSVF
EEEECCHHCCCCCHHHHHHHHHHHCCCCCCCCHHHHCHHHHCCCCCCCCCCHHHHHHHHH
MTFSKEGFLSDYRILRSVIRSKYRMTYDEVDEIIEKKLAHPISKTILEMAELSRIFSDIR
HHHCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EQRGCTRLVLPSFTMSLDNLQEPVALVENKQTAAHKLIEEFMLKANEVIAYHISHQGITM
HHCCCCEEECCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCEEEEEECCCCEEE
PFRIHEPPNEENLLLFRETAKAMGFTITQTPTQEPDYQYLLQETSAGHPLEPILHSQFVR
EEEECCCCCCCCEEEEEEHHHHHCEEEECCCCCCCCHHHHHHHCCCCCCCHHHHHHHHHH
SMKTASYSTENKGHYGLCLDYYTHFTSPIRRYVDLIVHRLLFHPLSVEEGHLEQIVRACS
HHHHHCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHC
SQERVAAKAEGAFINIKKARFLKKFLDEQPATLYKAFIITVSPEGLSFVLPELCHEGFIP
CHHHHHHHCCCCEEEHHHHHHHHHHHCCCCHHEEEEEEEEECCCCHHHHHHHHHHCCCCC
AAKLPKKYVIKTKLGLEELPEHLLPGIPISVQLASVTLLTQAIEWTLIESKERSSSKKKK
HHHCCHHHEEHHHCCHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHEECCHHHHHHHHHH
AKAKSNATQVKKKSSSKKKKAVSKAKKNRGGK
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10684935