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Identifier: 15835279

GI number: 15835279

Start: 792894

End: 793274

Strand: Reverse

Name: Not Available

Synonym: TC0664

Alternate gene names: 15835279

Gene position: 793274-792894 (Counterclockwise)

Preceding gene: 15835280

Following gene: 15835278

Centisome position: 73.93

GC content: 38.85

Gene sequence:

>381_bases
TTGCGAAGAAGCACTGAATTTGGTGTTAAAACAGCAGGGGGTAGTATGACTACAATTTTTGAACGAATTATAGAGGGAGC
TGTAGAGTGTGATAAGGTTTTTGAGGATGAAAATTTTATCGTGATTAAGGATAAATTTCCTCAAGCACCAGTGCATTTGC
TCATTATTCCAAAGAAGCATATTGAAAAATTACAAGATATGCAAAGCGACGATTTTTCCTTGCTTTCGGAAGCTGGGAAG
ATTATTCAGTTGATGGCCCGTGATTTCGGTATAGAAAATGGATATCGTGTTGTTATCAACAATGGCTTAGAAGGAGGGCA
GAGCGTATTCCATCTACATATCCATCTTCTTGGTGGAGGCTTGTTAGGCTCCATAGCATAA

Upstream 100 bases:

>100_bases
CAGGGTTGCTTGGGGATCAATTGGTTAAGGCTACAGGGATTCCTGGAGCGATTTTTTGCCATAAAGGGTTATTCCTCTCT
GTTTGGGATAGTCGGGAAAG

Downstream 100 bases:

>100_bases
TTTACTTCTTTGTAACGTGTTGTGCGGATTCTTCTGACTCTATTAGAAGGCATTTGCTTTTTCATGAGTACCGTACAGCC
GCTCAAGAGGCAAAAAATCT

Product: HIT family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 126; Mature: 126

Protein sequence:

>126_residues
MRRSTEFGVKTAGGSMTTIFERIIEGAVECDKVFEDENFIVIKDKFPQAPVHLLIIPKKHIEKLQDMQSDDFSLLSEAGK
IIQLMARDFGIENGYRVVINNGLEGGQSVFHLHIHLLGGGLLGSIA

Sequences:

>Translated_126_residues
MRRSTEFGVKTAGGSMTTIFERIIEGAVECDKVFEDENFIVIKDKFPQAPVHLLIIPKKHIEKLQDMQSDDFSLLSEAGK
IIQLMARDFGIENGYRVVINNGLEGGQSVFHLHIHLLGGGLLGSIA
>Mature_126_residues
MRRSTEFGVKTAGGSMTTIFERIIEGAVECDKVFEDENFIVIKDKFPQAPVHLLIIPKKHIEKLQDMQSDDFSLLSEAGK
IIQLMARDFGIENGYRVVINNGLEGGQSVFHLHIHLLGGGLLGSIA

Specific function: Unknown

COG id: COG0537

COG function: function code FGR; Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HIT domain

Homologues:

Organism=Homo sapiens, GI14211923, Length=109, Percent_Identity=44.954128440367, Blast_Score=106, Evalue=5e-24,
Organism=Homo sapiens, GI4885413, Length=111, Percent_Identity=44.1441441441441, Blast_Score=99, Evalue=1e-21,
Organism=Escherichia coli, GI1787346, Length=109, Percent_Identity=38.5321100917431, Blast_Score=71, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17506713, Length=102, Percent_Identity=43.1372549019608, Blast_Score=98, Evalue=8e-22,
Organism=Drosophila melanogaster, GI28574010, Length=110, Percent_Identity=42.7272727272727, Blast_Score=100, Evalue=3e-22,
Organism=Drosophila melanogaster, GI24581222, Length=110, Percent_Identity=42.7272727272727, Blast_Score=100, Evalue=4e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y664_CHLMU (Q9PK09)

Other databases:

- EMBL:   AE002160
- RefSeq:   NP_297038.1
- ProteinModelPortal:   Q9PK09
- SMR:   Q9PK09
- GeneID:   1246025
- GenomeReviews:   AE002160_GR
- KEGG:   cmu:TC0664
- TIGR:   TC_0664
- HOGENOM:   HBG743217
- OMA:   NCNRHGG
- ProtClustDB:   CLSK871348
- BioCyc:   CMUR243161:TC_0664-MONOMER
- InterPro:   IPR011146
- InterPro:   IPR011151
- InterPro:   IPR019808
- InterPro:   IPR001310
- Gene3D:   G3DSA:3.30.428.10
- PANTHER:   PTHR23089
- PRINTS:   PR00332

Pfam domain/function: PF01230 HIT; SSF54197 His_triad-like_motif

EC number: NA

Molecular weight: Translated: 13938; Mature: 13938

Theoretical pI: Translated: 5.99; Mature: 5.99

Prosite motif: PS00892 HIT_1; PS51084 HIT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRSTEFGVKTAGGSMTTIFERIIEGAVECDKVFEDENFIVIKDKFPQAPVHLLIIPKKH
CCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCEEEEEECHHH
IEKLQDMQSDDFSLLSEAGKIIQLMARDFGIENGYRVVINNGLEGGQSVFHLHIHLLGGG
HHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCEEEEEEEEEECCC
LLGSIA
HHCCCC
>Mature Secondary Structure
MRRSTEFGVKTAGGSMTTIFERIIEGAVECDKVFEDENFIVIKDKFPQAPVHLLIIPKKH
CCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCEEEEEECHHH
IEKLQDMQSDDFSLLSEAGKIIQLMARDFGIENGYRVVINNGLEGGQSVFHLHIHLLGGG
HHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCEEEEEEEEEECCC
LLGSIA
HHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10684935