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Identifier: 15835275

GI number: 15835275

Start: 788320

End: 789099

Strand: Reverse

Name: Not Available

Synonym: TC0660

Alternate gene names: 15835275

Gene position: 789099-788320 (Counterclockwise)

Preceding gene: 15835276

Following gene: 15835274

Centisome position: 73.54

GC content: 38.59

Gene sequence:

>780_bases
GTGAGTATGTATATAAAAAGAAAGAAAGCTTGGATGACTTTCTTAGCAATTGTCTGTAGTTTCTGTTTGGCGGGCTGTTC
AAAAGAGAGCAAAGACTCTGTTAGTGAAAAATTTATTGTAGGAACTAACGCAACGTATCCTCCTTTTGAGTTTGTTGATG
AAAGAGGTGAGACGGTTGGCTTTGATATTGATTTAGCTAGGGAGATTAGTAAAAAGCTAGGGAAAAAATTAGAAGTCCGA
GAATTTGCTTTTGATGCACTCGTTCTCAATTTAAAACAGCATCGTATTGATGCAATTATGGCAGGGGTGTCCATTACGTC
TTCTCGATTGAAAGAAATTTTGATGATTCCCTACTATGGCGAAGAAATAAAGAGTTTGGTTTTAGTGTTTAAGGATGGAG
ACTCAAAGTCTTTACCACTAGATCAGTATAATTCTGTTGCTGTTCAAACTGGCACGTACCAAGAGGAATATTTACAGTCT
CTTCCAGGGGTGCGTATTCGCTCTTTTGATAGTACTTTAGAAGTGCTTATGGAAGTTTTGCATAGCAAGTCTCCTATAGC
TGTTTTAGAACCGTCTATTGCGCAGGTCGTTTTAAAAGATTTTCCGACGCTCACTACTGAAACGATAGATCTTCCTGAAG
ATAAATGGGTTTTAGGGTATGGAATTGGAGTTGCTTCTGATCGACCATCTCTAGCTTCTGATATAGAAGCTGCTGTACAA
GAGATCAAGAAAGAAGGAGTGTTAGCAGAGTTAGAGCAAAAATGGGGTTTGAACGGCTAA

Upstream 100 bases:

>100_bases
AAACAAGCGCATTATCGAAAGAAGAAGTTTTCGTATAGATTCTTATTTTTTTTAAGAATTATGCTGGGTATAGTCCCTGT
CGTTAGACCTTTGAGCCGGA

Downstream 100 bases:

>100_bases
ACTCAAAACGATACTAAGAGGCCCTTATATGGAGGAAATATCTTCTTCTGGGAAGGTCATTTTTTTGGGCACAGGGGATC
CGGAAGGAACTCCTGTGCCA

Product: amino acid ABC transporter, periplasmic amino acid-binding protein

Products: ADP; phosphate; L-arginine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 259; Mature: 258

Protein sequence:

>259_residues
MSMYIKRKKAWMTFLAIVCSFCLAGCSKESKDSVSEKFIVGTNATYPPFEFVDERGETVGFDIDLAREISKKLGKKLEVR
EFAFDALVLNLKQHRIDAIMAGVSITSSRLKEILMIPYYGEEIKSLVLVFKDGDSKSLPLDQYNSVAVQTGTYQEEYLQS
LPGVRIRSFDSTLEVLMEVLHSKSPIAVLEPSIAQVVLKDFPTLTTETIDLPEDKWVLGYGIGVASDRPSLASDIEAAVQ
EIKKEGVLAELEQKWGLNG

Sequences:

>Translated_259_residues
MSMYIKRKKAWMTFLAIVCSFCLAGCSKESKDSVSEKFIVGTNATYPPFEFVDERGETVGFDIDLAREISKKLGKKLEVR
EFAFDALVLNLKQHRIDAIMAGVSITSSRLKEILMIPYYGEEIKSLVLVFKDGDSKSLPLDQYNSVAVQTGTYQEEYLQS
LPGVRIRSFDSTLEVLMEVLHSKSPIAVLEPSIAQVVLKDFPTLTTETIDLPEDKWVLGYGIGVASDRPSLASDIEAAVQ
EIKKEGVLAELEQKWGLNG
>Mature_258_residues
SMYIKRKKAWMTFLAIVCSFCLAGCSKESKDSVSEKFIVGTNATYPPFEFVDERGETVGFDIDLAREISKKLGKKLEVRE
FAFDALVLNLKQHRIDAIMAGVSITSSRLKEILMIPYYGEEIKSLVLVFKDGDSKSLPLDQYNSVAVQTGTYQEEYLQSL
PGVRIRSFDSTLEVLMEVLHSKSPIAVLEPSIAQVVLKDFPTLTTETIDLPEDKWVLGYGIGVASDRPSLASDIEAAVQE
IKKEGVLAELEQKWGLNG

Specific function: Probably part of an ABC transporter complex involved in arginine transport. Binds arginine. Interacts with host epithelial cells, suggesting a role in host-cell adhesion during infection [H]

COG id: COG0834

COG function: function code ET; ABC-type amino acid transport/signal transduction systems, periplasmic component/domain

Gene ontology:

Cell location: Secreted. Cell surface [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 3 family [H]

Homologues:

Organism=Escherichia coli, GI1787085, Length=248, Percent_Identity=28.6290322580645, Blast_Score=107, Evalue=9e-25,
Organism=Escherichia coli, GI1787088, Length=244, Percent_Identity=28.6885245901639, Blast_Score=104, Evalue=5e-24,
Organism=Escherichia coli, GI1788648, Length=237, Percent_Identity=28.2700421940928, Blast_Score=85, Evalue=6e-18,
Organism=Escherichia coli, GI1788228, Length=261, Percent_Identity=26.8199233716475, Blast_Score=84, Evalue=8e-18,
Organism=Escherichia coli, GI1788649, Length=235, Percent_Identity=27.6595744680851, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1787031, Length=257, Percent_Identity=26.0700389105058, Blast_Score=66, Evalue=3e-12,

Paralogues:

None

Copy number: 1180 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001638 [H]

Pfam domain/function: PF00497 SBP_bac_3 [H]

EC number: NA

Molecular weight: Translated: 28842; Mature: 28710

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSMYIKRKKAWMTFLAIVCSFCLAGCSKESKDSVSEKFIVGTNATYPPFEFVDERGETVG
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCEEEECCCCCCCCHHHHHCCCCEEC
FDIDLAREISKKLGKKLEVREFAFDALVLNLKQHRIDAIMAGVSITSSRLKEILMIPYYG
CCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCC
EEIKSLVLVFKDGDSKSLPLDQYNSVAVQTGTYQEEYLQSLPGVRIRSFDSTLEVLMEVL
HHHHEEEEEEECCCCCCCCCCCCCCEEEECCCCHHHHHHHCCCCEEECHHHHHHHHHHHH
HSKSPIAVLEPSIAQVVLKDFPTLTTETIDLPEDKWVLGYGIGVASDRPSLASDIEAAVQ
HCCCCCEEECHHHHHHHHHHCCCCCEEEECCCCCCEEEEECCCCCCCCCHHHHHHHHHHH
EIKKEGVLAELEQKWGLNG
HHHHCCHHHHHHHHCCCCC
>Mature Secondary Structure 
SMYIKRKKAWMTFLAIVCSFCLAGCSKESKDSVSEKFIVGTNATYPPFEFVDERGETVG
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCEEEECCCCCCCCHHHHHCCCCEEC
FDIDLAREISKKLGKKLEVREFAFDALVLNLKQHRIDAIMAGVSITSSRLKEILMIPYYG
CCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCC
EEIKSLVLVFKDGDSKSLPLDQYNSVAVQTGTYQEEYLQSLPGVRIRSFDSTLEVLMEVL
HHHHEEEEEEECCCCCCCCCCCCCCEEEECCCCHHHHHHHCCCCEEECHHHHHHHHHHHH
HSKSPIAVLEPSIAQVVLKDFPTLTTETIDLPEDKWVLGYGIGVASDRPSLASDIEAAVQ
HCCCCCEEECHHHHHHHHHHCCCCCEEEECCCCCCEEEEECCCCCCCCCHHHHHHHHHHH
EIKKEGVLAELEQKWGLNG
HHHHCCHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-arginine [Periplasm]; H2O [C]

Specific reaction: ATP + L-arginine [Periplasm] + H2O = ADP + phosphate + L-arginine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9784136 [H]