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Identifier: 15835266

GI number: 15835266

Start: 778254

End: 779669

Strand: Direct

Name: Not Available

Synonym: TC0651

Alternate gene names: 15835266

Gene position: 778254-779669 (Clockwise)

Preceding gene: 15835265

Following gene: 15835267

Centisome position: 72.53

GC content: 42.16

Gene sequence:

>1416_bases
ATGAATGGAAAAGTTCTGTGTGAGGTTTCTGTGTCCTTCCGTTCGATTCTGCTGACGGCTCTGCTTTCACTTTCTTTTAC
AAACACTATGCAGGCTGCACACCATCATTATCACCGTTATGATGATAAACTACGCAGACAATACCATAAAAAGGACTTGC
CCACTCAAGAGAATGTTCGGAAAGAGTTTTGTAATCCCTACTCTCATAGTAGTGATCCTATCCCTTTGTCACAACAACGA
GGAGTCCTATCTCCTATCTGTGATTTAGTCTCAGAGTGCTCGTTTTTGAACGGGATTTCCGTTAGGAGTCTTAAACAAAC
ACTGAAAAATTCTGCTGGGACTCAAGTTGCTTTAGACTGGTCTATCCTTCCTCAATGGTTCAATCCTAGATCCTCTTGGG
CTCCTAAGCTCTCTATTCGAGATCTTGGATATGGTAAACCCCAGTCCCTTATTGAAGCAGATTCCCCTTGTTGTCAAACC
TGCTTCAACCCATCTGCTGCTATTACGATTTACGATTCTTCATGTGGGAAGGGTGTTGTCCAAGTGTCATACACCCTTGT
TCGTTATTGGAGAGAAACGGCTGCACTTGCAGGGCAAACTATGATGCTTGCAGGAAGTATTAATGATTATCCTGCTCGCC
AAAACATATTCTCTCAACTTACATTTTCCCAAACTTTCCCTAATGAGAGAGTAAATCTAACTGTTGGTCAATACTCTCTT
TACTCGATAGACGGAACGCTGTACAACAATGATCAGCAGCTAGGATTTATTAGTTATGCGTTGTCGCAAAATCCAACAGC
GACTTATTCCTCTGGAAGCCTTGGCGCCTATCTACAAGTCGCTCCAACAGAAAGCACCTGTCTTCAAGTTGGGTTCCAAG
ATGCCTATAATATTTCAGGTTCCTCGATCAAATGGAATAATCTTACAAAAAATAAGTATAACTTCCATGGCTATGCATCT
TGGGCTCCACACTGTTGCTTAGGACCTGGACAATACTCTGTTCTTCTTTATGTAACCAGAAAGGTTCCTGAGCAAATGAT
GCAGACAATGGGCTGGTCTGTGAATGCAAGTCAATACATCTCTTCTAAACTTTATGTATTTGGAAGATACAGCGGAGTCA
CAGGCCAATTGTCTCCTATTAACCGAACCTATTCATTTGGCTTAGTCTCTCCTAATTTATTGAACCGTAACCCACAAGAC
TTATTTGGAGTAGCTTGCGCATTCAATAATATACACGCCTCCGCCTTTCAAAATGCTCAAAGAAAATATGAAACTGTGAT
CGAGGGATTTGCAACTATTGGTTGCGGACCTTACATCTCCTTTGCTCCAGATTTCCAACTTTACCTCTATCCTGCTCTGC
GTCCAAATAAACAAAGCGCCCGAGTCTATAGCGTTCGCGCAAACCTAGCTATTTAG

Upstream 100 bases:

>100_bases
AAGCAATGAAGCTGCAGCCCTTTTATTACGTCACCGTCTCGATAAATAGTTCCTACTGAAATAGAAATTAAACCTAGATA
AAAAAATTTATTTCTACTAC

Downstream 100 bases:

>100_bases
TAGGTTTGCACGAATACCTAGGGGGGCTTTGTAGTTAAATACCTTAATAACCCCAAAAAAGGAGGCATTATGCCTTACGG
AACTCGTTATCCAACATTAG

Product: hypothetical protein

Products: NA

Alternate protein names: Outer membrane protein AaxA [H]

Number of amino acids: Translated: 471; Mature: 471

Protein sequence:

>471_residues
MNGKVLCEVSVSFRSILLTALLSLSFTNTMQAAHHHYHRYDDKLRRQYHKKDLPTQENVRKEFCNPYSHSSDPIPLSQQR
GVLSPICDLVSECSFLNGISVRSLKQTLKNSAGTQVALDWSILPQWFNPRSSWAPKLSIRDLGYGKPQSLIEADSPCCQT
CFNPSAAITIYDSSCGKGVVQVSYTLVRYWRETAALAGQTMMLAGSINDYPARQNIFSQLTFSQTFPNERVNLTVGQYSL
YSIDGTLYNNDQQLGFISYALSQNPTATYSSGSLGAYLQVAPTESTCLQVGFQDAYNISGSSIKWNNLTKNKYNFHGYAS
WAPHCCLGPGQYSVLLYVTRKVPEQMMQTMGWSVNASQYISSKLYVFGRYSGVTGQLSPINRTYSFGLVSPNLLNRNPQD
LFGVACAFNNIHASAFQNAQRKYETVIEGFATIGCGPYISFAPDFQLYLYPALRPNKQSARVYSVRANLAI

Sequences:

>Translated_471_residues
MNGKVLCEVSVSFRSILLTALLSLSFTNTMQAAHHHYHRYDDKLRRQYHKKDLPTQENVRKEFCNPYSHSSDPIPLSQQR
GVLSPICDLVSECSFLNGISVRSLKQTLKNSAGTQVALDWSILPQWFNPRSSWAPKLSIRDLGYGKPQSLIEADSPCCQT
CFNPSAAITIYDSSCGKGVVQVSYTLVRYWRETAALAGQTMMLAGSINDYPARQNIFSQLTFSQTFPNERVNLTVGQYSL
YSIDGTLYNNDQQLGFISYALSQNPTATYSSGSLGAYLQVAPTESTCLQVGFQDAYNISGSSIKWNNLTKNKYNFHGYAS
WAPHCCLGPGQYSVLLYVTRKVPEQMMQTMGWSVNASQYISSKLYVFGRYSGVTGQLSPINRTYSFGLVSPNLLNRNPQD
LFGVACAFNNIHASAFQNAQRKYETVIEGFATIGCGPYISFAPDFQLYLYPALRPNKQSARVYSVRANLAI
>Mature_471_residues
MNGKVLCEVSVSFRSILLTALLSLSFTNTMQAAHHHYHRYDDKLRRQYHKKDLPTQENVRKEFCNPYSHSSDPIPLSQQR
GVLSPICDLVSECSFLNGISVRSLKQTLKNSAGTQVALDWSILPQWFNPRSSWAPKLSIRDLGYGKPQSLIEADSPCCQT
CFNPSAAITIYDSSCGKGVVQVSYTLVRYWRETAALAGQTMMLAGSINDYPARQNIFSQLTFSQTFPNERVNLTVGQYSL
YSIDGTLYNNDQQLGFISYALSQNPTATYSSGSLGAYLQVAPTESTCLQVGFQDAYNISGSSIKWNNLTKNKYNFHGYAS
WAPHCCLGPGQYSVLLYVTRKVPEQMMQTMGWSVNASQYISSKLYVFGRYSGVTGQLSPINRTYSFGLVSPNLLNRNPQD
LFGVACAFNNIHASAFQNAQRKYETVIEGFATIGCGPYISFAPDFQLYLYPALRPNKQSARVYSVRANLAI

Specific function: Facilitates L-arginine uptake, as part of the AaxABC system. The arginine uptake by the bacterium in the macrophage may be a virulence factor against the host innate immune response [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the oprB family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007049 [H]

Pfam domain/function: PF04966 OprB [H]

EC number: NA

Molecular weight: Translated: 52550; Mature: 52550

Theoretical pI: Translated: 8.91; Mature: 8.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNGKVLCEVSVSFRSILLTALLSLSFTNTMQAAHHHYHRYDDKLRRQYHKKDLPTQENVR
CCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
KEFCNPYSHSSDPIPLSQQRGVLSPICDLVSECSFLNGISVRSLKQTLKNSAGTQVALDW
HHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCEEEEEH
SILPQWFNPRSSWAPKLSIRDLGYGKPQSLIEADSPCCQTCFNPSAAITIYDSSCGKGVV
EECCCCCCCCCCCCCCEEEECCCCCCCHHHHHCCCCHHHHHCCCCEEEEEEECCCCCCCH
QVSYTLVRYWRETAALAGQTMMLAGSINDYPARQNIFSQLTFSQTFPNERVNLTVGQYSL
HHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCEEEEECCEEE
YSIDGTLYNNDQQLGFISYALSQNPTATYSSGSLGAYLQVAPTESTCLQVGFQDAYNISG
EEECCEEECCCCCEEEEEEECCCCCCCEECCCCCCEEEEEECCCCHHEEECCCHHCCCCC
SSIKWNNLTKNKYNFHGYASWAPHCCLGPGQYSVLLYVTRKVPEQMMQTMGWSVNASQYI
CEEEECCCCCCCCCCCEECCCCCCEECCCCCEEEEEEEEHHHHHHHHHHCCCCCCHHHHH
SSKLYVFGRYSGVTGQLSPINRTYSFGLVSPNLLNRNPQDLFGVACAFNNIHASAFQNAQ
CCEEEEEEEECCCCCCCCCCCCEEEECCCCCHHHCCCHHHHHHHHHHHCCHHHHHHHHHH
RKYETVIEGFATIGCGPYISFAPDFQLYLYPALRPNKQSARVYSVRANLAI
HHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCCCCCCEEEEEEECCCC
>Mature Secondary Structure
MNGKVLCEVSVSFRSILLTALLSLSFTNTMQAAHHHYHRYDDKLRRQYHKKDLPTQENVR
CCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
KEFCNPYSHSSDPIPLSQQRGVLSPICDLVSECSFLNGISVRSLKQTLKNSAGTQVALDW
HHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCEEEEEH
SILPQWFNPRSSWAPKLSIRDLGYGKPQSLIEADSPCCQTCFNPSAAITIYDSSCGKGVV
EECCCCCCCCCCCCCCEEEECCCCCCCHHHHHCCCCHHHHHCCCCEEEEEEECCCCCCCH
QVSYTLVRYWRETAALAGQTMMLAGSINDYPARQNIFSQLTFSQTFPNERVNLTVGQYSL
HHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCEEEEECCEEE
YSIDGTLYNNDQQLGFISYALSQNPTATYSSGSLGAYLQVAPTESTCLQVGFQDAYNISG
EEECCEEECCCCCEEEEEEECCCCCCCEECCCCCCEEEEEECCCCHHEEECCCHHCCCCC
SSIKWNNLTKNKYNFHGYASWAPHCCLGPGQYSVLLYVTRKVPEQMMQTMGWSVNASQYI
CEEEECCCCCCCCCCCEECCCCCCEECCCCCEEEEEEEEHHHHHHHHHHCCCCCCHHHHH
SSKLYVFGRYSGVTGQLSPINRTYSFGLVSPNLLNRNPQDLFGVACAFNNIHASAFQNAQ
CCEEEEEEEECCCCCCCCCCCCEEEECCCCCHHHCCCHHHHHHHHHHHCCHHHHHHHHHH
RKYETVIEGFATIGCGPYISFAPDFQLYLYPALRPNKQSARVYSVRANLAI
HHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCCCCCCEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10684935 [H]