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The map label for this gene is incA

Identifier: 15835015

GI number: 15835015

Start: 457696

End: 458526

Strand: Reverse

Name: incA

Synonym: TC0396

Alternate gene names: 15835015

Gene position: 458526-457696 (Counterclockwise)

Preceding gene: 15835022

Following gene: 15835007

Centisome position: 42.74

GC content: 37.91

Gene sequence:

>831_bases
ATGACATCACCTACTCTAGTTGAGATGCCTCTATCTTGCTATCCCCCAACACATACCAGTTCAACAGCCTGCACAAAAAG
AAGCTCATCACTCTATAAGCCCTCATTAATAGAAACTGTTCAACGAGTGGCTGCTTTTGTTTCCTTAGCTATCTTAAGCA
TAATAGGCTTTCTGGCTATCTTAGGGCATGCTATTGGTTTTCTGATAGCTCCACAAGTTGCCCTAGTTCTTATTGCGGTA
TTTATCATTTCCTTATTAGGAAATGCTCTCTACTTATGCAAAACGGCTCCATTACGTCTATACAAAGAGCTTCAACAAGA
GGTTGCGTCTCTAAAAGAAGTAAATTTCTTGTTAAAATCTGTTCAAAAGGAATTTTTAGGGTTATCAAAAGATTTCGCAA
CAACCTCCAAAGACCTCTCTGATGTATCCCTAGATTTTCATAATCTCCTACAAGATTTTCAATCTTCCCATCAAGGGTTT
GAGGACCTACTGGAGGACTATAAAAATTCTGCAGAGGATCTTCGTCAAATTTTTTCTCAAGAAACCGTGCAGAGTCTCAA
AAGTACTATCCTATCATTAAAAGAAGAGATAAAAGAGATCGTCCCATTGACTGAGGAAGTTCGCCGTTTGGCTGAGAATA
AAGAAGATTTACTAAAGATTGTTCAAGATCTGCAAGATATTCGAGATAAATTACGAGCAGAAATCAATAACCTTTCGCAA
GCCTCCAAAACATTAAGTGAGCAGATCGCATCGCAAATAGAAGAAAATGAAAAACTTTACGCCAATATAACAAAAGCGCT
CTCTCAATCTTATTCTGATTCTTCCGCCTAA

Upstream 100 bases:

>100_bases
AACATTTTATAGTCAAATCACAACCTATTTTCACATAGAATTTTTTATATAAAAAACCCTACAATCTGCTTACAATAAAT
TTTAAAATACGCAAGTACTT

Downstream 100 bases:

>100_bases
AATATTTGATCCTTCGCTCACGATTAAGGCACTCTTCAGAGTGAGTGCCTTTGCCAATTTTTCTATCCTAATTTAAAGGC
AAAGTCTTCCATACAGAAAC

Product: inclusion membrane localised protein IncA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 276; Mature: 275

Protein sequence:

>276_residues
MTSPTLVEMPLSCYPPTHTSSTACTKRSSSLYKPSLIETVQRVAAFVSLAILSIIGFLAILGHAIGFLIAPQVALVLIAV
FIISLLGNALYLCKTAPLRLYKELQQEVASLKEVNFLLKSVQKEFLGLSKDFATTSKDLSDVSLDFHNLLQDFQSSHQGF
EDLLEDYKNSAEDLRQIFSQETVQSLKSTILSLKEEIKEIVPLTEEVRRLAENKEDLLKIVQDLQDIRDKLRAEINNLSQ
ASKTLSEQIASQIEENEKLYANITKALSQSYSDSSA

Sequences:

>Translated_276_residues
MTSPTLVEMPLSCYPPTHTSSTACTKRSSSLYKPSLIETVQRVAAFVSLAILSIIGFLAILGHAIGFLIAPQVALVLIAV
FIISLLGNALYLCKTAPLRLYKELQQEVASLKEVNFLLKSVQKEFLGLSKDFATTSKDLSDVSLDFHNLLQDFQSSHQGF
EDLLEDYKNSAEDLRQIFSQETVQSLKSTILSLKEEIKEIVPLTEEVRRLAENKEDLLKIVQDLQDIRDKLRAEINNLSQ
ASKTLSEQIASQIEENEKLYANITKALSQSYSDSSA
>Mature_275_residues
TSPTLVEMPLSCYPPTHTSSTACTKRSSSLYKPSLIETVQRVAAFVSLAILSIIGFLAILGHAIGFLIAPQVALVLIAVF
IISLLGNALYLCKTAPLRLYKELQQEVASLKEVNFLLKSVQKEFLGLSKDFATTSKDLSDVSLDFHNLLQDFQSSHQGFE
DLLEDYKNSAEDLRQIFSQETVQSLKSTILSLKEEIKEIVPLTEEVRRLAENKEDLLKIVQDLQDIRDKLRAEINNLSQA
SKTLSEQIASQIEENEKLYANITKALSQSYSDSSA

Specific function: Chlamydia replicate within an intracellular vacuole, termed an inclusion. IncA is involved in the homotypic fusion of inclusions [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Secreted. Host cell membrane; Multi-pass membrane protein (Potential). Note=Secreted, probably via type III secretion system. Localized to the cytosolic face of the inclusion membrane (By similarity) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007285 [H]

Pfam domain/function: PF04156 IncA [H]

EC number: NA

Molecular weight: Translated: 30745; Mature: 30613

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSPTLVEMPLSCYPPTHTSSTACTKRSSSLYKPSLIETVQRVAAFVSLAILSIIGFLAI
CCCCCHHHCCCCCCCCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LGHAIGFLIAPQVALVLIAVFIISLLGNALYLCKTAPLRLYKELQQEVASLKEVNFLLKS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VQKEFLGLSKDFATTSKDLSDVSLDFHNLLQDFQSSHQGFEDLLEDYKNSAEDLRQIFSQ
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ETVQSLKSTILSLKEEIKEIVPLTEEVRRLAENKEDLLKIVQDLQDIRDKLRAEINNLSQ
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHH
ASKTLSEQIASQIEENEKLYANITKALSQSYSDSSA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TSPTLVEMPLSCYPPTHTSSTACTKRSSSLYKPSLIETVQRVAAFVSLAILSIIGFLAI
CCCCHHHCCCCCCCCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LGHAIGFLIAPQVALVLIAVFIISLLGNALYLCKTAPLRLYKELQQEVASLKEVNFLLKS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VQKEFLGLSKDFATTSKDLSDVSLDFHNLLQDFQSSHQGFEDLLEDYKNSAEDLRQIFSQ
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ETVQSLKSTILSLKEEIKEIVPLTEEVRRLAENKEDLLKIVQDLQDIRDKLRAEINNLSQ
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHH
ASKTLSEQIASQIEENEKLYANITKALSQSYSDSSA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10603409; 11402010; 12177343; 9784136 [H]