Click here to switch to the map view.

The map label for this gene is groES

Identifier: 15835006

GI number: 15835006

Start: 448832

End: 449140

Strand: Reverse

Name: groES

Synonym: TC0387

Alternate gene names: 15835006

Gene position: 449140-448832 (Counterclockwise)

Preceding gene: 15835007

Following gene: 15835005

Centisome position: 41.86

GC content: 38.83

Gene sequence:

>309_bases
ATGTCAGATCAAGCAACAACCCTCAAGATTAAACCTTTGGGAGATAGAATTTTAGTTAAAAGAGAAGAAGAAGCTTCTAC
TGCAAGAGGTGGAATCATTCTTCCTGATACTGCTAAGAAAAAACAAGACAGAGCTGAAGTTTTGGCTTTAGGAACTGGCA
AAAAAGATGATAAAGGGCAGCAGCTTCCTTTTGAAGTTCAGGTTGGCGACATCGTTTTAATTGATAAGTATTCTGGCCAA
GAACTCACTGTCGAAGGTGAAGAATATGTCATCGTTCAAATGAGCGAAGTTATAGCAGTCCTGCAATAA

Upstream 100 bases:

>100_bases
TCCCCCTCTGAACGTTCTGTCGTTCAAATCCCTACGTTGATAGCGGAGAGGCGCTGAACAACGAGGCCTCATAGAATGTG
AAAATACGAGGAGCTTAAAC

Downstream 100 bases:

>100_bases
AAACTAAGAGAGTGAAGTAAGATTTAAGGAGCGCATCGATGGTCGCTAAAAATATTAAATATAACGAAGAAGCCAGAAAA
AAAATTCAAAAAGGAGTTAA

Product: co-chaperonin GroES

Products: NA

Alternate protein names: 11.2 kDa stress response protein; GroES protein; Heat shock protein 10; HSP10; Protein Cpn10

Number of amino acids: Translated: 102; Mature: 101

Protein sequence:

>102_residues
MSDQATTLKIKPLGDRILVKREEEASTARGGIILPDTAKKKQDRAEVLALGTGKKDDKGQQLPFEVQVGDIVLIDKYSGQ
ELTVEGEEYVIVQMSEVIAVLQ

Sequences:

>Translated_102_residues
MSDQATTLKIKPLGDRILVKREEEASTARGGIILPDTAKKKQDRAEVLALGTGKKDDKGQQLPFEVQVGDIVLIDKYSGQ
ELTVEGEEYVIVQMSEVIAVLQ
>Mature_101_residues
SDQATTLKIKPLGDRILVKREEEASTARGGIILPDTAKKKQDRAEVLALGTGKKDDKGQQLPFEVQVGDIVLIDKYSGQE
LTVEGEEYVIVQMSEVIAVLQ

Specific function: Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter

COG id: COG0234

COG function: function code O; Co-chaperonin GroES (HSP10)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GroES chaperonin family

Homologues:

Organism=Escherichia coli, GI1790585, Length=96, Percent_Identity=38.5416666666667, Blast_Score=74, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17555568, Length=93, Percent_Identity=36.5591397849462, Blast_Score=68, Evalue=1e-12,
Organism=Drosophila melanogaster, GI21356029, Length=97, Percent_Identity=36.0824742268041, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: 980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 5720 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). 1274 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): CH10_CHLMU (P17204)

Other databases:

- EMBL:   L12004
- EMBL:   U52049
- EMBL:   AE002160
- PIR:   E81709
- RefSeq:   NP_296765.1
- ProteinModelPortal:   P17204
- SMR:   P17204
- GeneID:   1245739
- GenomeReviews:   AE002160_GR
- KEGG:   cmu:TC0387
- TIGR:   TC_0387
- HOGENOM:   HBG703377
- OMA:   VEYMVLE
- ProtClustDB:   PRK00364
- BioCyc:   CMUR243161:TC_0387-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00580
- InterPro:   IPR020818
- InterPro:   IPR018369
- InterPro:   IPR011032
- Gene3D:   G3DSA:2.30.33.40
- PANTHER:   PTHR10772
- PRINTS:   PR00297
- SMART:   SM00883

Pfam domain/function: PF00166 Cpn10; SSF50129 GroES_like

EC number: NA

Molecular weight: Translated: 11183; Mature: 11052

Theoretical pI: Translated: 4.58; Mature: 4.58

Prosite motif: PS00681 CHAPERONINS_CPN10

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDQATTLKIKPLGDRILVKREEEASTARGGIILPDTAKKKQDRAEVLALGTGKKDDKGQ
CCCCCEEEEEEECCCEEEEEECCCCCCCCCCEEECCCCCCCCCCEEEEEECCCCCCCCCC
QLPFEVQVGDIVLIDKYSGQELTVEGEEYVIVQMSEVIAVLQ
CCCEEEEECCEEEEECCCCCEEEECCCEEEEEEECHHHEECC
>Mature Secondary Structure 
SDQATTLKIKPLGDRILVKREEEASTARGGIILPDTAKKKQDRAEVLALGTGKKDDKGQ
CCCCEEEEEEECCCEEEEEECCCCCCCCCCEEECCCCCCCCCCEEEEEECCCCCCCCCC
QLPFEVQVGDIVLIDKYSGQELTVEGEEYVIVQMSEVIAVLQ
CCCEEEEECCEEEEECCCCCEEEECCCEEEEEEECHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7909303; 8955323; 10684935