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The map label for this gene is acpS

Identifier: 15834995

GI number: 15834995

Start: 438048

End: 438425

Strand: Direct

Name: acpS

Synonym: TC0376

Alternate gene names: 15834995

Gene position: 438048-438425 (Clockwise)

Preceding gene: 15834994

Following gene: 15834996

Centisome position: 40.83

GC content: 42.59

Gene sequence:

>378_bases
ATGTTTGGGATAGGGACTGACATTATAGAAATTGATAGGATTCGCAGAGCTTATCACACTTATGGGGATCGATTCCTAAA
CAAAATTTTTACGAAAGGGGAGCAGGCTTACTGTTTTTCTAAGTCGGATCCCTATGCTTCTTTGGCAGTGCGTTTTGCTG
CTAAAGAGGCTGTATCCAAAGCTTTGGGTACGGGTATAGGTAAATCTTTGAAATGGAAAGAAATCGAAATATCTAGGGGG
ACTCAACACCCCCAAGTTTCCGTTCCGGAGTCTTTGCTGGCTTTGCTGGAGGTGAAAAGAATCCTTCTTTCCATGAGTCA
CTGTCGAGAGTATGCCACCGCAGTAGCTATTGCAGAAGTAACTAATAGTAGTAAATAG

Upstream 100 bases:

>100_bases
GAGATGTTCAAGACAAGTATTATAGACAAGCCATTACTTCCGCAGGTAGCGGGTGTATGGCGGCTTTAGATGCTGAAAGA
TTTTTAGAAAAATAAGTTTT

Downstream 100 bases:

>100_bases
AGTATTTAGCTTTTAGTTCTTTAAGCAGCTTCCAGTGAGCAAGGCTTGCTTTGAAAAGGGCATAGCTGACGGAAGAGCAC
ATAAGAAATGAGAACAGTGG

Product: 4'-phosphopantetheinyl transferase

Products: NA

Alternate protein names: Holo-ACP synthase; 4'-phosphopantetheinyl transferase AcpS

Number of amino acids: Translated: 125; Mature: 125

Protein sequence:

>125_residues
MFGIGTDIIEIDRIRRAYHTYGDRFLNKIFTKGEQAYCFSKSDPYASLAVRFAAKEAVSKALGTGIGKSLKWKEIEISRG
TQHPQVSVPESLLALLEVKRILLSMSHCREYATAVAIAEVTNSSK

Sequences:

>Translated_125_residues
MFGIGTDIIEIDRIRRAYHTYGDRFLNKIFTKGEQAYCFSKSDPYASLAVRFAAKEAVSKALGTGIGKSLKWKEIEISRG
TQHPQVSVPESLLALLEVKRILLSMSHCREYATAVAIAEVTNSSK
>Mature_125_residues
MFGIGTDIIEIDRIRRAYHTYGDRFLNKIFTKGEQAYCFSKSDPYASLAVRFAAKEAVSKALGTGIGKSLKWKEIEISRG
TQHPQVSVPESLLALLEVKRILLSMSHCREYATAVAIAEVTNSSK

Specific function: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein

COG id: COG0736

COG function: function code I; Phosphopantetheinyl transferase (holo-ACP synthase)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the P-Pant transferase superfamily. AcpS family

Homologues:

Organism=Escherichia coli, GI1788916, Length=123, Percent_Identity=34.1463414634146, Blast_Score=65, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACPS_CHLMU (Q9PKT6)

Other databases:

- EMBL:   AE002160
- PIR:   D81710
- RefSeq:   NP_296754.1
- ProteinModelPortal:   Q9PKT6
- SMR:   Q9PKT6
- GeneID:   1245728
- GenomeReviews:   AE002160_GR
- KEGG:   cmu:TC0376
- TIGR:   TC_0376
- HOGENOM:   HBG734479
- OMA:   MAISPNI
- ProtClustDB:   PRK00070
- BioCyc:   CMUR243161:TC_0376-MONOMER
- BRENDA:   2.7.8.7
- GO:   GO:0005737
- HAMAP:   MF_00101
- InterPro:   IPR008278
- InterPro:   IPR002582
- InterPro:   IPR004568
- ProDom:   PD004282
- TIGRFAMs:   TIGR00516
- TIGRFAMs:   TIGR00556

Pfam domain/function: PF01648 ACPS; SSF56214 4-PPT_transf

EC number: =2.7.8.7

Molecular weight: Translated: 13897; Mature: 13897

Theoretical pI: Translated: 9.70; Mature: 9.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFGIGTDIIEIDRIRRAYHTYGDRFLNKIFTKGEQAYCFSKSDPYASLAVRFAAKEAVSK
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHH
ALGTGIGKSLKWKEIEISRGTQHPQVSVPESLLALLEVKRILLSMSHCREYATAVAIAEV
HHHCCCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TNSSK
HCCCC
>Mature Secondary Structure
MFGIGTDIIEIDRIRRAYHTYGDRFLNKIFTKGEQAYCFSKSDPYASLAVRFAAKEAVSK
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHH
ALGTGIGKSLKWKEIEISRGTQHPQVSVPESLLALLEVKRILLSMSHCREYATAVAIAEV
HHHCCCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TNSSK
HCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10684935