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The map label for this gene is trxB

Identifier: 15834994

GI number: 15834994

Start: 437104

End: 438042

Strand: Direct

Name: trxB

Synonym: TC0375

Alternate gene names: 15834994

Gene position: 437104-438042 (Clockwise)

Preceding gene: 15834993

Following gene: 15834995

Centisome position: 40.74

GC content: 42.6

Gene sequence:

>939_bases
ATGACACATGTAAAGTTAGCCATTATAGGCTCTGGGCCTGCAGGTTACACGGCTGCTATCTATGCTTCTAGAGCGCTTTT
GACCCCAATACTATTTGAAGGATTCTTTTCTGGTATCGCTGGAGGCCAATTAATGACTACGACTGAAGTGGAAAATTTTC
CGGGGTTCCCTCAAGGGGTGTTGGGTCATCAGCTCATGGAAAATATGAAAATGCAAGCCCAGCGTTTTGGCACGCAGGTG
ATTGCTAAAGACATCACTTCTGTAGATTTCAGTGTTAGACCTTTTGTTCTGAAATCCGGAGAAGATACTTTTACATGTGA
CGCGTGCATTATAGCTACAGGGGCTTCGGCCAAGAGATTATCTATTCCAGGTGCAGGGGATAATGAATTTTGGCAAAAAG
GTGTGACAGCATGTGCAGTTTGCGATGGAGCTTCCCCCATTTTTAGAGATCGGGATTTATTTGTTATTGGAGGGGGAGAT
TCTGCTTTGGAAGAGGCCATGTTTTTGACTCGTTATGGTAAGCGTGTATTCGTTGTGCATAGAAGGGATACTTTGCGTGC
TTCAAAGGCTATGGTGAATAAGGCTCAAGCTAATGAGAAAATTGTTTTTCTCTGGAATAGTGAAGTAGTAAAAATATTGG
GGGATTCTTTGGTTCGTTCCATTGATATTTTTAATAATGTCGAGAAGACTACTGTAACAATGGAAGCCGCTGGAGTTTTC
TTTGCTATTGGGCATCAGCCCAATACAGCATTCTTAGGGGGGCAGTTGTCCTTAGATGAGAATGGATATATTATTACAGA
GAAGGGAAGTTCTCGAACATCGGTTCCCGGAGTTTTTGCTGCAGGAGATGTTCAAGACAAGTATTATAGACAAGCCATTA
CTTCCGCAGGTAGCGGGTGTATGGCGGCTTTAGATGCTGAAAGATTTTTAGAAAAATAA

Upstream 100 bases:

>100_bases
AGTTTGGTTAGTTATAGTTCCTTTTTGCAAAATCAAGAAGACTTTTCCCTATATATTTGCAGCTCTTTTATCCTTATCTA
AGTTTGTATCAGGAGTTCCC

Downstream 100 bases:

>100_bases
GTTTTATGTTTGGGATAGGGACTGACATTATAGAAATTGATAGGATTCGCAGAGCTTATCACACTTATGGGGATCGATTC
CTAAACAAAATTTTTACGAA

Product: thioredoxin reductase

Products: NA

Alternate protein names: TRXR

Number of amino acids: Translated: 312; Mature: 311

Protein sequence:

>312_residues
MTHVKLAIIGSGPAGYTAAIYASRALLTPILFEGFFSGIAGGQLMTTTEVENFPGFPQGVLGHQLMENMKMQAQRFGTQV
IAKDITSVDFSVRPFVLKSGEDTFTCDACIIATGASAKRLSIPGAGDNEFWQKGVTACAVCDGASPIFRDRDLFVIGGGD
SALEEAMFLTRYGKRVFVVHRRDTLRASKAMVNKAQANEKIVFLWNSEVVKILGDSLVRSIDIFNNVEKTTVTMEAAGVF
FAIGHQPNTAFLGGQLSLDENGYIITEKGSSRTSVPGVFAAGDVQDKYYRQAITSAGSGCMAALDAERFLEK

Sequences:

>Translated_312_residues
MTHVKLAIIGSGPAGYTAAIYASRALLTPILFEGFFSGIAGGQLMTTTEVENFPGFPQGVLGHQLMENMKMQAQRFGTQV
IAKDITSVDFSVRPFVLKSGEDTFTCDACIIATGASAKRLSIPGAGDNEFWQKGVTACAVCDGASPIFRDRDLFVIGGGD
SALEEAMFLTRYGKRVFVVHRRDTLRASKAMVNKAQANEKIVFLWNSEVVKILGDSLVRSIDIFNNVEKTTVTMEAAGVF
FAIGHQPNTAFLGGQLSLDENGYIITEKGSSRTSVPGVFAAGDVQDKYYRQAITSAGSGCMAALDAERFLEK
>Mature_311_residues
THVKLAIIGSGPAGYTAAIYASRALLTPILFEGFFSGIAGGQLMTTTEVENFPGFPQGVLGHQLMENMKMQAQRFGTQVI
AKDITSVDFSVRPFVLKSGEDTFTCDACIIATGASAKRLSIPGAGDNEFWQKGVTACAVCDGASPIFRDRDLFVIGGGDS
ALEEAMFLTRYGKRVFVVHRRDTLRASKAMVNKAQANEKIVFLWNSEVVKILGDSLVRSIDIFNNVEKTTVTMEAAGVFF
AIGHQPNTAFLGGQLSLDENGYIITEKGSSRTSVPGVFAAGDVQDKYYRQAITSAGSGCMAALDAERFLEK

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family

Homologues:

Organism=Escherichia coli, GI1787114, Length=322, Percent_Identity=49.0683229813665, Blast_Score=287, Evalue=7e-79,
Organism=Escherichia coli, GI87081763, Length=299, Percent_Identity=29.7658862876254, Blast_Score=122, Evalue=3e-29,
Organism=Saccharomyces cerevisiae, GI6320560, Length=317, Percent_Identity=56.1514195583596, Blast_Score=353, Evalue=2e-98,
Organism=Saccharomyces cerevisiae, GI6321898, Length=317, Percent_Identity=52.9968454258675, Blast_Score=331, Evalue=7e-92,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): TRXB_CHLMU (Q9PKT7)

Other databases:

- EMBL:   AE002160
- PIR:   C81710
- RefSeq:   NP_296753.1
- ProteinModelPortal:   Q9PKT7
- GeneID:   1245727
- GenomeReviews:   AE002160_GR
- KEGG:   cmu:TC0375
- TIGR:   TC_0375
- HOGENOM:   HBG669726
- OMA:   PSCGPCH
- PhylomeDB:   Q9PKT7
- ProtClustDB:   CLSK871182
- BioCyc:   CMUR243161:TC_0375-MONOMER
- BRENDA:   1.8.1.9
- GO:   GO:0005737
- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982
- PRINTS:   PR00368
- PRINTS:   PR00469
- TIGRFAMs:   TIGR01292

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2

EC number: =1.8.1.9

Molecular weight: Translated: 33557; Mature: 33426

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS00573 PYRIDINE_REDOX_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTHVKLAIIGSGPAGYTAAIYASRALLTPILFEGFFSGIAGGQLMTTTEVENFPGFPQGV
CCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCHH
LGHQLMENMKMQAQRFGTQVIAKDITSVDFSVRPFVLKSGEDTFTCDACIIATGASAKRL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCEEEECCCCCEEECEEEEECCCCCCEE
SIPGAGDNEFWQKGVTACAVCDGASPIFRDRDLFVIGGGDSALEEAMFLTRYGKRVFVVH
ECCCCCCHHHHHHCCCEEEEECCCCCCCCCCCEEEEECCCHHHHHHHHHHHCCCEEEEEE
RRDTLRASKAMVNKAQANEKIVFLWNSEVVKILGDSLVRSIDIFNNVEKTTVTMEAAGVF
CCHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHHHCCCCCEEEEEEECEEE
FAIGHQPNTAFLGGQLSLDENGYIITEKGSSRTSVPGVFAAGDVQDKYYRQAITSAGSGC
EEECCCCCCEEECCEEEECCCCEEEEECCCCCCCCCEEEEECCCHHHHHHHHHHCCCCCC
MAALDAERFLEK
EEHHHHHHHHCC
>Mature Secondary Structure 
THVKLAIIGSGPAGYTAAIYASRALLTPILFEGFFSGIAGGQLMTTTEVENFPGFPQGV
CEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCHH
LGHQLMENMKMQAQRFGTQVIAKDITSVDFSVRPFVLKSGEDTFTCDACIIATGASAKRL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCEEEECCCCCEEECEEEEECCCCCCEE
SIPGAGDNEFWQKGVTACAVCDGASPIFRDRDLFVIGGGDSALEEAMFLTRYGKRVFVVH
ECCCCCCHHHHHHCCCEEEEECCCCCCCCCCCEEEEECCCHHHHHHHHHHHCCCEEEEEE
RRDTLRASKAMVNKAQANEKIVFLWNSEVVKILGDSLVRSIDIFNNVEKTTVTMEAAGVF
CCHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHHHCCCCCEEEEEEECEEE
FAIGHQPNTAFLGGQLSLDENGYIITEKGSSRTSVPGVFAAGDVQDKYYRQAITSAGSGC
EEECCCCCCEEECCEEEECCCCEEEEECCCCCCCCCEEEEECCCHHHHHHHHHHCCCCCC
MAALDAERFLEK
EEHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10684935