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Identifier: 15834986

GI number: 15834986

Start: 427875

End: 428969

Strand: Direct

Name: Not Available

Synonym: TC0367

Alternate gene names: 15834986

Gene position: 427875-428969 (Clockwise)

Preceding gene: 15834975

Following gene: 15834993

Centisome position: 39.88

GC content: 41.1

Gene sequence:

>1095_bases
ATGGGACAAACAGAGTGCGGAATAGTAGGGCTTCCTAATGTAGGAAAATCGGGGTTATTTAACGCGTTAACAGGTGCGCA
GGTTGCTTCTTGTAATTATCCTTTTTGCACGATTGATCCTAATGTTGGTATCGTTCCAGTTGTTGATTCTAGGTTAGAGA
TTTTGGCTCGTATTAGTCAGAGTCACAAGATTATCTATGCAGATATGAAATTTGTGGACATTGCAGGACTAGTAAAAGGT
GCTGCAAGTGGCGCTGGGTTAGGGAACCGCTTTTTATCGCATATTCGAGAAACTCATGCAATTGCTCATGTTGTGCGCTG
TTTTGATAATGATGATGTGACGCACGTATCTGGAAAGATCGATCCAGAGGAAGATATTGCTGTTATCAACCTGGAACTGA
TACTAGCAGATTTTTCTTCTGCTACTAGTGTTCGTGATAAACTTAGCAAACAGGCTAAAGGGAAGAAAGATATAGGACAA
TTAATCCCTATTTTAGATCGAGTAATTGAACATTTAGAATCGGGAAACCCTGTTCGAACGCTTTCTCTTTCTTCTGAAGA
AGGAAGTTTATTGAAACCCTATCCGTTCCTTACAGGAAAGCCTATGCTTTATATTGCTAACATTGACGAAGATTCCTTAA
CAGATTTAGACAATCCCTATGTCCAGAAAGTACGGAGGATTGCCCAACAAGAAGGGGCTAACGTCGTGCCTATTTGTGTA
AAATTAGAAGAAGAGATTCTGTCTCTTCCTCCGGAAGAGCGGCAAGACTTTTTACATAGTTTGGGCTTACAAGAATCTGG
GCTAAATCGTTTAGTAGCTTCTGCATATCAGACCTTAGGGCTAATTTCTTATTTCACTACAGGTCCACAAGAGACGAGAG
CTTGGACAATTTCTAAGGGAGCAACTGCTGCAGAAGCTGCAGGAGAAATTCATTCAGATATTCAAAAAGGATTTATTCGT
GCTGAGGTGGTGACTTTAGAAGATATCGTTACCTATAATGGAAGGGCTGGAGCTCGAGAAGCAGGTAAATTACGAGCAGA
GGGTCGGGACTATATTGTTCAGGACGGAGATATCATGCTGTTTCTGCATAACTAA

Upstream 100 bases:

>100_bases
GCTAATCTTGCTTTTTCTTTAGAATCTCTCTTCCCTTGTCAGTTAAGAAAGAAAGGCATTTTTTGCCTTTAAAAAAGAAT
CAAAATTTCTGGGTAATAAA

Downstream 100 bases:

>100_bases
AAGGGGATGTGGCTTTTTTAACTTAAACGAGCTTTGCGTATATCCTCTTGAATAGCAAGAGCAAGTTCCTTTTGAGAAGA
AAAAGTTTTTTCTTCTCTAA

Product: GTP-dependent nucleic acid-binding protein EngD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 364; Mature: 363

Protein sequence:

>364_residues
MGQTECGIVGLPNVGKSGLFNALTGAQVASCNYPFCTIDPNVGIVPVVDSRLEILARISQSHKIIYADMKFVDIAGLVKG
AASGAGLGNRFLSHIRETHAIAHVVRCFDNDDVTHVSGKIDPEEDIAVINLELILADFSSATSVRDKLSKQAKGKKDIGQ
LIPILDRVIEHLESGNPVRTLSLSSEEGSLLKPYPFLTGKPMLYIANIDEDSLTDLDNPYVQKVRRIAQQEGANVVPICV
KLEEEILSLPPEERQDFLHSLGLQESGLNRLVASAYQTLGLISYFTTGPQETRAWTISKGATAAEAAGEIHSDIQKGFIR
AEVVTLEDIVTYNGRAGAREAGKLRAEGRDYIVQDGDIMLFLHN

Sequences:

>Translated_364_residues
MGQTECGIVGLPNVGKSGLFNALTGAQVASCNYPFCTIDPNVGIVPVVDSRLEILARISQSHKIIYADMKFVDIAGLVKG
AASGAGLGNRFLSHIRETHAIAHVVRCFDNDDVTHVSGKIDPEEDIAVINLELILADFSSATSVRDKLSKQAKGKKDIGQ
LIPILDRVIEHLESGNPVRTLSLSSEEGSLLKPYPFLTGKPMLYIANIDEDSLTDLDNPYVQKVRRIAQQEGANVVPICV
KLEEEILSLPPEERQDFLHSLGLQESGLNRLVASAYQTLGLISYFTTGPQETRAWTISKGATAAEAAGEIHSDIQKGFIR
AEVVTLEDIVTYNGRAGAREAGKLRAEGRDYIVQDGDIMLFLHN
>Mature_363_residues
GQTECGIVGLPNVGKSGLFNALTGAQVASCNYPFCTIDPNVGIVPVVDSRLEILARISQSHKIIYADMKFVDIAGLVKGA
ASGAGLGNRFLSHIRETHAIAHVVRCFDNDDVTHVSGKIDPEEDIAVINLELILADFSSATSVRDKLSKQAKGKKDIGQL
IPILDRVIEHLESGNPVRTLSLSSEEGSLLKPYPFLTGKPMLYIANIDEDSLTDLDNPYVQKVRRIAQQEGANVVPICVK
LEEEILSLPPEERQDFLHSLGLQESGLNRLVASAYQTLGLISYFTTGPQETRAWTISKGATAAEAAGEIHSDIQKGFIRA
EVVTLEDIVTYNGRAGAREAGKLRAEGRDYIVQDGDIMLFLHN

Specific function: GTP-dependent nucleic acid-binding protein which may act as a translation factor [H]

COG id: COG0012

COG function: function code J; Predicted GTPase, probable translation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI58761500, Length=366, Percent_Identity=42.6229508196721, Blast_Score=283, Evalue=2e-76,
Organism=Homo sapiens, GI58761502, Length=196, Percent_Identity=38.265306122449, Blast_Score=144, Evalue=1e-34,
Organism=Escherichia coli, GI1787454, Length=361, Percent_Identity=53.7396121883656, Blast_Score=411, Evalue=1e-116,
Organism=Escherichia coli, GI1789574, Length=129, Percent_Identity=33.3333333333333, Blast_Score=73, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17509631, Length=364, Percent_Identity=40.1098901098901, Blast_Score=275, Evalue=3e-74,
Organism=Saccharomyces cerevisiae, GI6319499, Length=367, Percent_Identity=38.6920980926431, Blast_Score=248, Evalue=1e-66,
Organism=Saccharomyces cerevisiae, GI6321773, Length=377, Percent_Identity=34.2175066312997, Blast_Score=211, Evalue=2e-55,
Organism=Saccharomyces cerevisiae, GI6321649, Length=200, Percent_Identity=32.5, Blast_Score=73, Evalue=9e-14,
Organism=Drosophila melanogaster, GI24640873, Length=366, Percent_Identity=39.6174863387978, Blast_Score=262, Evalue=3e-70,
Organism=Drosophila melanogaster, GI24640877, Length=366, Percent_Identity=39.6174863387978, Blast_Score=262, Evalue=3e-70,
Organism=Drosophila melanogaster, GI24640875, Length=366, Percent_Identity=39.6174863387978, Blast_Score=262, Evalue=3e-70,
Organism=Drosophila melanogaster, GI24640879, Length=328, Percent_Identity=37.5, Blast_Score=215, Evalue=5e-56,

Paralogues:

None

Copy number: 120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012675
- InterPro:   IPR004396
- InterPro:   IPR013029
- InterPro:   IPR006073
- InterPro:   IPR002917
- InterPro:   IPR012676
- InterPro:   IPR023192 [H]

Pfam domain/function: PF01926 MMR_HSR1; PF06071 YchF-GTPase_C [H]

EC number: NA

Molecular weight: Translated: 39519; Mature: 39388

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: PS00443 GATASE_TYPE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGQTECGIVGLPNVGKSGLFNALTGAQVASCNYPFCTIDPNVGIVPVVDSRLEILARISQ
CCCCCCCEEECCCCCCCHHHHHHCCCEEEECCCCEEEECCCCCEEEEHHHHHHHHHHHHH
SHKIIYADMKFVDIAGLVKGAASGAGLGNRFLSHIRETHAIAHVVRCFDNDDVTHVSGKI
CCEEEEECCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCC
DPEEDIAVINLELILADFSSATSVRDKLSKQAKGKKDIGQLIPILDRVIEHLESGNPVRT
CCCCCEEEEEEEEEEECCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCEEE
LSLSSEEGSLLKPYPFLTGKPMLYIANIDEDSLTDLDNPYVQKVRRIAQQEGANVVPICV
EEECCCCCCEECCCCCCCCCCEEEEEECCCHHHCCCCCHHHHHHHHHHHHCCCCEEEEEE
KLEEEILSLPPEERQDFLHSLGLQESGLNRLVASAYQTLGLISYFTTGPQETRAWTISKG
EEHHHHHCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCC
ATAAEAAGEIHSDIQKGFIRAEVVTLEDIVTYNGRAGAREAGKLRAEGRDYIVQDGDIML
CCHHHHHHHHHHHHHHHHHHHEEEEHHHHHEECCCCCCCHHHHHHCCCCCEEEECCCEEE
FLHN
EEEC
>Mature Secondary Structure 
GQTECGIVGLPNVGKSGLFNALTGAQVASCNYPFCTIDPNVGIVPVVDSRLEILARISQ
CCCCCCEEECCCCCCCHHHHHHCCCEEEECCCCEEEECCCCCEEEEHHHHHHHHHHHHH
SHKIIYADMKFVDIAGLVKGAASGAGLGNRFLSHIRETHAIAHVVRCFDNDDVTHVSGKI
CCEEEEECCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCC
DPEEDIAVINLELILADFSSATSVRDKLSKQAKGKKDIGQLIPILDRVIEHLESGNPVRT
CCCCCEEEEEEEEEEECCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCEEE
LSLSSEEGSLLKPYPFLTGKPMLYIANIDEDSLTDLDNPYVQKVRRIAQQEGANVVPICV
EEECCCCCCEECCCCCCCCCCEEEEEECCCHHHCCCCCHHHHHHHHHHHHCCCCEEEEEE
KLEEEILSLPPEERQDFLHSLGLQESGLNRLVASAYQTLGLISYFTTGPQETRAWTISKG
EEHHHHHCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCC
ATAAEAAGEIHSDIQKGFIRAEVVTLEDIVTYNGRAGAREAGKLRAEGRDYIVQDGDIML
CCHHHHHHHHHHHHHHHHHHHEEEEHHHHHEECCCCCCCHHHHHHCCCCCEEEECCCEEE
FLHN
EEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]